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Items: 1 to 50 of 58

1.

Surface-dependent endocytosis of poly(isobutylcyanoacrylate) nanoparticles by Trichomonas vaginalis.

Malli S, Bories C, Bourge M, Loiseau PM, Bouchemal K.

Int J Pharm. 2018 Sep 5;548(1):276-287. doi: 10.1016/j.ijpharm.2018.07.006. Epub 2018 Jul 3.

PMID:
29991450
2.

Hierarchical supramolecular platelets from hydrophobically-modified polysaccharides and α-cyclodextrin: Effect of hydrophobization and α-cyclodextrin concentration on platelet formation.

Diaz-Salmeron R, Ponchel G, Gallard JF, Bouchemal K.

Int J Pharm. 2018 Sep 5;548(1):227-236. doi: 10.1016/j.ijpharm.2018.06.061. Epub 2018 Jun 30.

PMID:
29966742
3.

New insights on the structure of hexagonally faceted platelets from hydrophobically modified chitosan and α-cyclodextrin.

Ahmed Z, Malli S, Diaz-Salmeron R, Destruel PL, Da Costa A, Guigner JM, Porcher F, Baptiste B, Ponchel G, Bouchemal K.

Int J Pharm. 2018 Sep 5;548(1):23-33. doi: 10.1016/j.ijpharm.2018.06.035. Epub 2018 Jun 21.

PMID:
29936201
4.

Phase solubility studies and anti-Trichomonas vaginalis activity evaluations of metronidazole and methylated β-cyclodextrin complexes: Comparison of CRYSMEB and RAMEB.

Malli S, Bories C, Ponchel G, Loiseau PM, Bouchemal K.

Exp Parasitol. 2018 Jun;189:72-75. doi: 10.1016/j.exppara.2018.04.019. Epub 2018 Apr 27.

PMID:
29730454
5.

Autoassemblies of α-Cyclodextrin and Grafted Polysaccharides: Crystal Structure and Specific Properties of the Platelets.

Carn F, Nowak S, Chaab I, Diaz-Salmeron R, Djabourov M, Bouchemal K.

J Phys Chem B. 2018 Jun 7;122(22):6055-6063. doi: 10.1021/acs.jpcb.8b01417. Epub 2018 May 25.

PMID:
29624401
6.

Strategies for Prevention and Treatment of Trichomonas vaginalis Infections.

Bouchemal K, Bories C, Loiseau PM.

Clin Microbiol Rev. 2017 Jul;30(3):811-825. doi: 10.1128/CMR.00109-16. Review.

7.

Supramolecular Chitosan Micro-Platelets Synergistically Enhance Anti-Candida albicans Activity of Amphotericin B Using an Immunocompetent Murine Model.

Grisin T, Bories C, Bombardi M, Loiseau PM, Rouffiac V, Solgadi A, Mallet JM, Ponchel G, Bouchemal K.

Pharm Res. 2017 May;34(5):1067-1082. doi: 10.1007/s11095-017-2117-3. Epub 2017 Feb 6.

PMID:
28168390
8.

M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures.

Musumeci G, Bon I, Lembo D, Cagno V, Re MC, Signoretto C, Diani E, Lopalco L, Pastori C, Martin L, Ponchel G, Gibellini D, Bouchemal K.

Sci Rep. 2017 Feb 1;7:41018. doi: 10.1038/srep41018.

9.

Cyclodextrin-mediated self-associating chitosan micro-platelets act as a drug booster against Candida glabrata mucosal infection in immunocompetent mice.

Grisin T, Bories C, Loiseau PM, Bouchemal K.

Int J Pharm. 2017 Mar 15;519(1-2):381-389. doi: 10.1016/j.ijpharm.2017.01.048. Epub 2017 Jan 24.

PMID:
28130196
10.

In situ forming pluronic® F127/chitosan hydrogel limits metronidazole transmucosal absorption.

Malli S, Bories C, Pradines B, Loiseau PM, Ponchel G, Bouchemal K.

Eur J Pharm Biopharm. 2017 Mar;112:143-147. doi: 10.1016/j.ejpb.2016.11.024. Epub 2016 Nov 24.

PMID:
27890510
11.

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge.

Ariën KK, Baleux F, Desjardins D, Porrot F, Coïc YM, Michiels J, Bouchemal K, Bonnaffé D, Bruel T, Schwartz O, Le Grand R, Vanham G, Dereuddre-Bosquet N, Lortat-Jacob H.

Sci Rep. 2016 Oct 10;6:34829. doi: 10.1038/srep34829.

12.

Pickering emulsions with α-cyclodextrin inclusions: Structure and thermal stability.

Diaz-Salmeron R, Chaab I, Carn F, Djabourov M, Bouchemal K.

J Colloid Interface Sci. 2016 Nov 15;482:48-57. doi: 10.1016/j.jcis.2016.07.033. Epub 2016 Jul 18.

PMID:
27491001
13.

Hexagonal-shaped chondroitin sulfate self-assemblies have exalted anti-HSV-2 activity.

Galus A, Mallet JM, Lembo D, Cagno V, Djabourov M, Lortat-Jacob H, Bouchemal K.

Carbohydr Polym. 2016 Jan 20;136:113-20. doi: 10.1016/j.carbpol.2015.08.054. Epub 2015 Aug 20.

PMID:
26572336
14.

Gelation and micellization behaviors of pluronic(®) F127 hydrogel containing poly(isobutylcyanoacrylate) nanoparticles specifically designed for mucosal application.

Pradines B, Djabourov M, Vauthier C, Loiseau PM, Ponchel G, Bouchemal K.

Colloids Surf B Biointerfaces. 2015 Nov 1;135:669-76. doi: 10.1016/j.colsurfb.2015.08.021. Epub 2015 Aug 22.

PMID:
26340355
15.

Cell line-dependent cytotoxicity of poly(isobutylcyanoacrylate) nanoparticles coated with chitosan and thiolated chitosan: Insights from cultured human epithelial HeLa, Caco2/TC7 and HT-29/MTX cells.

Pradines B, Lievin-Le Moal V, Vauthier C, Ponchel G, Loiseau PM, Bouchemal K.

Int J Pharm. 2015 Aug 1;491(1-2):17-20. doi: 10.1016/j.ijpharm.2015.06.001. Epub 2015 Jun 5.

PMID:
26051544
16.

Thermosensitive and mucoadhesive pluronic-hydroxypropylmethylcellulose hydrogel containing the mini-CD4 M48U1 is a promising efficient barrier against HIV diffusion through macaque cervicovaginal mucus.

Bouchemal K, Aka-Any-Grah A, Dereuddre-Bosquet N, Martin L, Lievin-Le-Moal V, Le Grand R, Nicolas V, Gibellini D, Lembo D, Poüs C, Koffi A, Ponchel G.

Antimicrob Agents Chemother. 2015 Apr;59(4):2215-22. doi: 10.1128/AAC.03503-14. Epub 2015 Feb 2.

17.

The unexpected increase of clotrimazole apparent solubility using randomly methylated β-cyclodextrin.

Pradines B, Gallard JF, Iorga BI, Gueutin C, Ponchel G, Loiseau PM, Bouchemal K.

J Mol Recognit. 2015 Feb;28(2):96-102. doi: 10.1002/jmr.2432. Epub 2015 Jan 21.

PMID:
25604751
18.

Dehydration, dissolution, and melting of cyclodextrin crystals.

Specogna E, Li KW, Djabourov M, Carn F, Bouchemal K.

J Phys Chem B. 2015 Jan 29;119(4):1433-42. doi: 10.1021/jp511631e. Epub 2015 Jan 17.

PMID:
25565266
19.

Drug-free chitosan coated poly(isobutylcyanoacrylate) nanoparticles are active against trichomonas vaginalis and non-toxic towards pig vaginal mucosa.

Pradines B, Bories C, Vauthier C, Ponchel G, Loiseau PM, Bouchemal K.

Pharm Res. 2015 Apr;32(4):1229-36. doi: 10.1007/s11095-014-1528-7. Epub 2014 Oct 16.

PMID:
25319099
20.

Investigation of the complexation of albendazole with cyclodextrins for the design of new antiparasitic formulations.

Pradines B, Gallard JF, Iorga BI, Gueutin C, Loiseau PM, Ponchel G, Bouchemal K.

Carbohydr Res. 2014 Oct 29;398:50-5. doi: 10.1016/j.carres.2014.06.008. Epub 2014 Jun 17.

PMID:
25240182
21.

Auto-associative heparin nanoassemblies: a biomimetic platform against the heparan sulfate-dependent viruses HSV-1, HSV-2, HPV-16 and RSV.

Lembo D, Donalisio M, Laine C, Cagno V, Civra A, Bianchini EP, Zeghbib N, Bouchemal K.

Eur J Pharm Biopharm. 2014 Sep;88(1):275-82. doi: 10.1016/j.ejpb.2014.05.007. Epub 2014 May 14.

22.

Scale-up of polyamide and polyester Parsol® MCX nanocapsules by interfacial polycondensation and solvent diffusion method.

Stumpo M, Anselmi C, Vauthier C, Mitri K, Hanno I, Huang N, Bouchemal K.

Int J Pharm. 2013 Oct 1;454(2):678-85. doi: 10.1016/j.ijpharm.2013.06.062. Epub 2013 Jul 5.

PMID:
23834834
23.

Clotrimazole-loaded nanostructured lipid carrier hydrogels: thermal analysis and in vitro studies.

Ravani L, Esposito E, Bories C, Moal VL, Loiseau PM, Djabourov M, Cortesi R, Bouchemal K.

Int J Pharm. 2013 Oct 1;454(2):695-702. doi: 10.1016/j.ijpharm.2013.06.015. Epub 2013 Jun 21.

PMID:
23792467
24.

Towards an improved anti-HIV activity of NRTI via metal-organic frameworks nanoparticles.

Agostoni V, Chalati T, Horcajada P, Willaime H, Anand R, Semiramoth N, Baati T, Hall S, Maurin G, Chacun H, Bouchemal K, Martineau C, Taulelle F, Couvreur P, Rogez-Kreuz C, Clayette P, Monti S, Serre C, Gref R.

Adv Healthc Mater. 2013 Dec;2(12):1630-7. doi: 10.1002/adhm.201200454. Epub 2013 Jun 17.

PMID:
23776182
25.

Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide.

Bouchemal K, Frelichowska J, Martin L, Lievin-Le Moal V, Le Grand R, Dereuddre-Bosquet N, Djabourov M, Aka-Any-Grah A, Koffi A, Ponchel G.

Int J Pharm. 2013 Oct 1;454(2):649-52. doi: 10.1016/j.ijpharm.2013.02.055. Epub 2013 Mar 7.

PMID:
23500765
26.

Nanostructured fluids from pluronic® mixtures.

Zhang M, Djabourov M, Bourgaux C, Bouchemal K.

Int J Pharm. 2013 Oct 1;454(2):599-610. doi: 10.1016/j.ijpharm.2013.01.043. Epub 2013 Jan 28.

PMID:
23370436
27.

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques.

Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, Augustijns P, Bouchemal K, Ponchel G, Ramos OH, Herrera C, Stefanidou M, Shattock R, Heyndrickx L, Vanham G, Kessler P, Le Grand R, Martin L.

PLoS Pathog. 2012;8(12):e1003071. doi: 10.1371/journal.ppat.1003071. Epub 2012 Dec 6.

28.

Oral delivery of anticancer drugs III: formulation using drug delivery systems.

Mazzaferro S, Bouchemal K, Ponchel G.

Drug Discov Today. 2013 Jan;18(1-2):99-104. doi: 10.1016/j.drudis.2012.08.007. Epub 2012 Sep 5. Review.

PMID:
22981667
29.

Oral delivery of anticancer drugs II: the prodrug strategy.

Mazzaferro S, Bouchemal K, Ponchel G.

Drug Discov Today. 2013 Jan;18(1-2):93-8. doi: 10.1016/j.drudis.2012.08.006. Epub 2012 Aug 30. Review.

PMID:
22960308
30.

Oral delivery of anticancer drugs I: general considerations.

Mazzaferro S, Bouchemal K, Ponchel G.

Drug Discov Today. 2013 Jan;18(1-2):25-34. doi: 10.1016/j.drudis.2012.08.004. Epub 2012 Aug 22. Review.

PMID:
22951365
31.

Intestinal permeation enhancement of docetaxel encapsulated into methyl-β-cyclodextrin/poly(isobutylcyanoacrylate) nanoparticles coated with thiolated chitosan.

Mazzaferro S, Bouchemal K, Skanji R, Gueutin C, Chacun H, Ponchel G.

J Control Release. 2012 Sep 28;162(3):568-74. doi: 10.1016/j.jconrel.2012.08.005. Epub 2012 Aug 10.

PMID:
22902592
32.

Scale-up of nanoemulsion produced by emulsification and solvent diffusion.

Mitri K, Vauthier C, Huang N, Menas A, Ringard-Lefebvre C, Anselmi C, Stambouli M, Rosilio V, Vachon JJ, Bouchemal K.

J Pharm Sci. 2012 Nov;101(11):4240-7. doi: 10.1002/jps.23291. Epub 2012 Aug 8.

PMID:
22886515
33.

How to conduct and interpret ITC experiments accurately for cyclodextrin-guest interactions.

Bouchemal K, Mazzaferro S.

Drug Discov Today. 2012 Jun;17(11-12):623-9. doi: 10.1016/j.drudis.2012.01.023. Epub 2012 Feb 3. Review.

PMID:
22326233
34.

Auto-associative amphiphilic polysaccharides as drug delivery systems.

Hassani LN, Hendra F, Bouchemal K.

Drug Discov Today. 2012 Jun;17(11-12):608-14. doi: 10.1016/j.drudis.2012.01.016. Epub 2012 Jan 25. Review.

PMID:
22305936
35.

The counterbalanced effect of size and surface properties of chitosan-coated poly(isobutylcyanoacrylate) nanoparticles on mucoadhesion due to pluronic F68 addition.

Petit B, Bouchemal K, Vauthier C, Djabourov M, Ponchel G.

Pharm Res. 2012 Apr;29(4):943-52. doi: 10.1007/s11095-011-0634-z. Epub 2011 Dec 7.

PMID:
22146804
36.

Polyamide nanocapsules and nano-emulsions containing Parsol® MCX and Parsol® 1789: in vitro release, ex vivo skin penetration and photo-stability studies.

Hanno I, Anselmi C, Bouchemal K.

Pharm Res. 2012 Feb;29(2):559-73. doi: 10.1007/s11095-011-0592-5. Epub 2011 Sep 23.

PMID:
21938595
37.

Bivalent sequential binding of docetaxel to methyl-β-cyclodextrin.

Mazzaferro S, Bouchemal K, Gallard JF, Iorga BI, Cheron M, Gueutin C, Steinmesse C, Ponchel G.

Int J Pharm. 2011 Sep 15;416(1):171-80. doi: 10.1016/j.ijpharm.2011.06.034. Epub 2011 Jun 25.

PMID:
21736931
38.

Synthesis and characterization of surface-modified PBLG nanoparticles for bone targeting: in vitro and in vivo evaluations.

Ozcan I, Bouchemal K, Segura-Sánchez F, Ozer O, Güneri T, Ponchel G.

J Pharm Sci. 2011 Nov;100(11):4877-87. doi: 10.1002/jps.22678. Epub 2011 Jun 22.

PMID:
21698603
39.

Pegylation of poly(γ-benzyl-L-glutamate) nanoparticles is efficient for avoiding mononuclear phagocyte system capture in rats.

Ozcan I, Segura-Sánchez F, Bouchemal K, Sezak M, Ozer O, Güneri T, Ponchel G.

Int J Nanomedicine. 2010 Dec 8;5:1103-11. doi: 10.2147/IJN.S15493.

40.

A comprehensive study of the spontaneous formation of nanoassemblies in water by a "lock-and-key" interaction between two associative polymers.

Othman M, Bouchemal K, Couvreur P, Desmaële D, Morvan E, Pouget T, Gref R.

J Colloid Interface Sci. 2011 Feb 15;354(2):517-27. doi: 10.1016/j.jcis.2010.11.015. Epub 2010 Dec 4.

PMID:
21131000
41.

PEGylation and preliminary biocompatibility evaluation of magnetite-silica nanocomposites obtained by high energy ball milling.

Pilloni M, Nicolas J, Marsaud V, Bouchemal K, Frongia F, Scano A, Ennas G, Dubernet C.

Int J Pharm. 2010 Nov 30;401(1-2):103-12. doi: 10.1016/j.ijpharm.2010.09.010. Epub 2010 Sep 18.

PMID:
20854884
42.

Cyclodextrin complexed insulin encapsulated hydrogel microparticles: An oral delivery system for insulin.

Sajeesh S, Bouchemal K, Marsaud V, Vauthier C, Sharma CP.

J Control Release. 2010 Nov 1;147(3):377-84. doi: 10.1016/j.jconrel.2010.08.007. Epub 2010 Aug 19.

PMID:
20727924
43.

Formulation of mucoadhesive vaginal hydrogels insensitive to dilution with vaginal fluids.

Aka-Any-Grah A, Bouchemal K, Koffi A, Agnely F, Zhang M, Djabourov M, Ponchel G.

Eur J Pharm Biopharm. 2010 Oct;76(2):296-303. doi: 10.1016/j.ejpb.2010.07.004. Epub 2010 Jul 23.

PMID:
20656027
44.

Synthesis and characterization of functionalized poly(gamma-benzyl-L-glutamate) derivates and corresponding nanoparticles preparation and characterization.

Segura-Sánchez F, Montembault V, Fontaine L, Martínez-Barbosa ME, Bouchemal K, Ponchel G.

Int J Pharm. 2010 Mar 15;387(1-2):244-52. doi: 10.1016/j.ijpharm.2009.12.016. Epub 2009 Dec 18.

PMID:
20005933
45.

What can isothermal titration microcalorimetry experiments tell us about the self-organization of surfactants into micelles?

Bouchemal K, Agnely F, Koffi A, Djabourov M, Ponchel G.

J Mol Recognit. 2010 Jul-Aug;23(4):335-42. doi: 10.1002/jmr.998. Review.

PMID:
19941321
46.

Combined hydroxypropyl-beta-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel.

Agüeros M, Ruiz-Gatón L, Vauthier C, Bouchemal K, Espuelas S, Ponchel G, Irache JM.

Eur J Pharm Sci. 2009 Nov 5;38(4):405-13. doi: 10.1016/j.ejps.2009.09.010. Epub 2009 Sep 16.

PMID:
19765652
47.

Surface-functionalized polymethacrylic acid based hydrogel microparticles for oral drug delivery.

Sajeesh S, Bouchemal K, Sharma CP, Vauthier C.

Eur J Pharm Biopharm. 2010 Feb;74(2):209-18. doi: 10.1016/j.ejpb.2009.09.001. Epub 2009 Sep 6.

PMID:
19737614
48.

A concise analysis of the effect of temperature and propanediol-1, 2 on Pluronic F127 micellization using isothermal titration microcalorimetry.

Bouchemal K, Agnely F, Koffi A, Ponchel G.

J Colloid Interface Sci. 2009 Oct 1;338(1):169-76. doi: 10.1016/j.jcis.2009.05.075. Epub 2009 Jun 6.

PMID:
19580975
49.

Microcalorimetric investigation on the formation of supramolecular nanoassemblies of associative polymers loaded with gadolinium chelate derivatives.

Othman M, Bouchemal K, Couvreur P, Gref R.

Int J Pharm. 2009 Sep 11;379(2):218-25. doi: 10.1016/j.ijpharm.2009.05.061. Epub 2009 Jun 6.

PMID:
19505542
50.

Parameters affecting organization and transfection efficiency of amphiphilic copolymers/DNA carriers.

Roques C, Bouchemal K, Ponchel G, Fromes Y, Fattal E.

J Control Release. 2009 Aug 19;138(1):71-7. doi: 10.1016/j.jconrel.2009.04.030. Epub 2009 May 4.

PMID:
19410613

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