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Items: 1 to 50 of 179

1.

TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life.

Eschenbrenner E, Jouannet S, Clay D, Chaker J, Boucheix C, Brou C, Tomlinson MG, Charrin S, Rubinstein E.

Life Sci Alliance. 2019 Dec 2;3(1). pii: e201900444. doi: 10.26508/lsa.201900444. Print 2020 Jan.

2.

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression.

Lazareth H, Henique C, Lenoir O, Puelles VG, Flamant M, Bollée G, Fligny C, Camus M, Guyonnet L, Millien C, Gaillard F, Chipont A, Robin B, Fabrega S, Dhaun N, Camerer E, Kretz O, Grahammer F, Braun F, Huber TB, Nochy D, Mandet C, Bruneval P, Mesnard L, Thervet E, Karras A, Le Naour F, Rubinstein E, Boucheix C, Alexandrou A, Moeller MJ, Bouzigues C, Tharaux PL.

Nat Commun. 2019 Jul 24;10(1):3303. doi: 10.1038/s41467-019-11013-2.

3.

Tspan8 is expressed in breast cancer and regulates E-cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles.

Voglstaetter M, Thomsen AR, Nouvel J, Koch A, Jank P, Navarro EG, Gainey-Schleicher T, Khanduri R, Groß A, Rossner F, Blaue C, Franz CM, Veil M, Puetz G, Hippe A, Dindorf J, Kashef J, Thiele W, Homey B, Greco C, Boucheix C, Baur A, Erbes T, Waller CF, Follo M, Hossein G, Sers C, Sleeman J, Nazarenko I.

J Pathol. 2019 Aug;248(4):421-437. doi: 10.1002/path.5281. Epub 2019 Jun 18.

4.

Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination.

Machover D, Rossi L, Hamelin J, Desterke C, Goldschmidt E, Chadefaux-Vekemans B, Bonnarme P, Briozzo P, Kopečný D, Pierigè F, Magnani M, Mollicone R, Haghighi-Rad F, Gaston-Mathé Y, Dairou J, Boucheix C, Saffroy R.

J Pharmacol Exp Ther. 2019 Jun;369(3):489-502. doi: 10.1124/jpet.119.256537. Epub 2019 Apr 2.

PMID:
30940696
5.

Targeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029.

Bonnet M, Maisonial-Besset A, Zhu Y, Witkowski T, Roche G, Boucheix C, Greco C, Degoul F.

Cancers (Basel). 2019 Feb 3;11(2). pii: E179. doi: 10.3390/cancers11020179. Review.

6.

JUNO, the receptor of sperm IZUMO1, is expressed by the human oocyte and is essential for human fertilisation.

Jean C, Haghighirad F, Zhu Y, Chalbi M, Ziyyat A, Rubinstein E, Gourier C, Yip P, Wolf JP, Lee JE, Boucheix C, Barraud-Lange V.

Hum Reprod. 2019 Jan 1;34(1):118-126. doi: 10.1093/humrep/dey340.

PMID:
30517645
7.

RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance.

Cajigas-Du Ross CK, Martinez SR, Woods-Burnham L, Durán AM, Roy S, Basu A, Ramirez JA, Ortiz-Hernández GL, Ríos-Colón L, Chirshev E, Sanchez-Hernandez ES, Soto U, Greco C, Boucheix C, Chen X, Unternaehrer J, Wang C, Casiano CA.

Oncotarget. 2018 Jul 13;9(54):30363-30384. doi: 10.18632/oncotarget.25744. eCollection 2018 Jul 13.

8.

Enhancement of 5-Fluorouracil Cytotoxicity by Pyridoxal 5'-Phosphate and Folinic Acid in Tandem.

Machover D, Goldschmidt E, Mollicone R, Haghighi-Rad F, Desterke C, Gaston-Mathé Y, Saffroy R, Boucheix C, Dairou J.

J Pharmacol Exp Ther. 2018 Aug;366(2):238-243. doi: 10.1124/jpet.118.249367. Epub 2018 Jun 1.

PMID:
29858389
9.

Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models.

Rondon A, Ty N, Bequignat JB, Quintana M, Briat A, Witkowski T, Bouchon B, Boucheix C, Miot-Noirault E, Pouget JP, Chezal JM, Navarro-Teulon I, Moreau E, Degoul F.

Sci Rep. 2017 Nov 2;7(1):14918. doi: 10.1038/s41598-017-15051-y.

10.

Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins.

Saint-Pol J, Eschenbrenner E, Dornier E, Boucheix C, Charrin S, Rubinstein E.

Biochem Soc Trans. 2017 Aug 15;45(4):937-44. doi: 10.1042/BST20160296. Epub 2017 Jul 7. Review.

PMID:
28687716
11.

CD9 Regulates Major Histocompatibility Complex Class II Trafficking in Monocyte-Derived Dendritic Cells.

Rocha-Perugini V, Martínez Del Hoyo G, González-Granado JM, Ramírez-Huesca M, Zorita V, Rubinstein E, Boucheix C, Sánchez-Madrid F.

Mol Cell Biol. 2017 Jul 14;37(15). pii: e00202-17. doi: 10.1128/MCB.00202-17. Print 2017 Aug 1.

12.

New insights into the tetraspanin Tspan5 using novel monoclonal antibodies.

Saint-Pol J, Billard M, Dornier E, Eschenbrenner E, Danglot L, Boucheix C, Charrin S, Rubinstein E.

J Biol Chem. 2017 Jun 9;292(23):9551-9566. doi: 10.1074/jbc.M116.765669. Epub 2017 Apr 20.

13.

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer.

Maisonial-Besset A, Witkowski T, Navarro-Teulon I, Berthier-Vergnes O, Fois G, Zhu Y, Besse S, Bawa O, Briat A, Quintana M, Pichard A, Bonnet M, Rubinstein E, Pouget JP, Opolon P, Maigne L, Miot-Noirault E, Chezal JM, Boucheix C, Degoul F.

Oncotarget. 2017 Mar 28;8(13):22034-22047. doi: 10.18632/oncotarget.15787.

14.

Multi-factorial modulation of colorectal carcinoma cells motility - partial coordination by the tetraspanin Co-029/tspan8.

Zhu Y, Ailane N, Sala-Valdés M, Haghighi-Rad F, Billard M, Nguyen V, Saffroy R, Lemoine A, Rubinstein E, Boucheix C, Greco C.

Oncotarget. 2017 Apr 18;8(16):27454-27470. doi: 10.18632/oncotarget.16247.

15.

IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process.

Le Coz V, Zhu C, Devocelle A, Vazquez A, Boucheix C, Azzi S, Gallerne C, Eid P, Lecourt S, Giron-Michel J.

Oncotarget. 2016 Dec 13;7(50):82511-82527. doi: 10.18632/oncotarget.12733.

16.

Correction: TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals.

Dornier E, Coumailleau F, Ottavi JF, Moretti J, Boucheix C, Mauduit P, Schweisguth F, Rubinstein E.

J Cell Biol. 2016 May 23;213(4):495-6. doi: 10.1083/jcb.20120113304262016c. Epub 2016 May 16. No abstract available.

17.

TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.

Jouannet S, Saint-Pol J, Fernandez L, Nguyen V, Charrin S, Boucheix C, Brou C, Milhiet PE, Rubinstein E.

Cell Mol Life Sci. 2016 May;73(9):1895-915. doi: 10.1007/s00018-015-2111-z. Epub 2015 Dec 19.

18.

CD81 controls immunity to Listeria infection through rac-dependent inhibition of proinflammatory mediator release and activation of cytotoxic T cells.

Martínez del Hoyo G, Ramírez-Huesca M, Levy S, Boucheix C, Rubinstein E, Minguito de la Escalera M, González-Cintado L, Ardavín C, Veiga E, Yáñez-Mó M, Sánchez-Madrid F.

J Immunol. 2015 Jun 15;194(12):6090-101. doi: 10.4049/jimmunol.1402957. Epub 2015 May 13.

19.

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis.

Desterke C, Martinaud C, Guerton B, Pieri L, Bogani C, Clay D, Torossian F, Lataillade JJ, Hasselbach HC, Gisslinger H, Demory JL, Dupriez B, Boucheix C, Rubinstein E, Amsellem S, Vannucchi AM, Le Bousse-Kerdilès MC.

Haematologica. 2015 Jun;100(6):757-67. doi: 10.3324/haematol.2014.118497. Epub 2015 Apr 3.

20.

Effect of an anti-human Co-029/tspan8 mouse monoclonal antibody on tumor growth in a nude mouse model.

Ailane N, Greco C, Zhu Y, Sala-Valdés M, Billard M, Casal I, Bawa O, Opolon P, Rubinstein E, Boucheix C.

Front Physiol. 2014 Sep 19;5:364. doi: 10.3389/fphys.2014.00364. eCollection 2014.

21.

Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilization.

Chalbi M, Barraud-Lange V, Ravaux B, Howan K, Rodriguez N, Soule P, Ndzoudi A, Boucheix C, Rubinstein E, Wolf JP, Ziyyat A, Perez E, Pincet F, Gourier C.

Development. 2014 Oct;141(19):3732-9. doi: 10.1242/dev.111534. Epub 2014 Sep 10.

22.

Tetraspanins at a glance.

Charrin S, Jouannet S, Boucheix C, Rubinstein E.

J Cell Sci. 2014 Sep 1;127(Pt 17):3641-8. doi: 10.1242/jcs.154906. Epub 2014 Aug 15. Review.

23.

Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner.

Copeland BT, Bowman MJ, Boucheix C, Ashman LK.

Int J Cancer. 2013 Oct 15;133(8):1803-12. doi: 10.1002/ijc.28204. Epub 2013 May 15.

24.

Normal muscle regeneration requires tight control of muscle cell fusion by tetraspanins CD9 and CD81.

Charrin S, Latil M, Soave S, Polesskaya A, Chrétien F, Boucheix C, Rubinstein E.

Nat Commun. 2013;4:1674. doi: 10.1038/ncomms2675.

PMID:
23575678
25.

Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria.

Obeid M, Franetich JF, Lorthiois A, Gego A, Grüner AC, Tefit M, Boucheix C, Snounou G, Mazier D.

EMBO Mol Med. 2013 Feb;5(2):250-63. doi: 10.1002/emmm.201201677. Epub 2012 Dec 19.

26.

TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals.

Dornier E, Coumailleau F, Ottavi JF, Moretti J, Boucheix C, Mauduit P, Schweisguth F, Rubinstein E.

J Cell Biol. 2012 Oct 29;199(3):481-96. doi: 10.1083/jcb.201201133. Epub 2012 Oct 22. Erratum in: J Cell Biol. 2016 May 23;213(4):495-6.

27.

Targeting tetraspanins in cancer.

Sala-Valdés M, Ailane N, Greco C, Rubinstein E, Boucheix C.

Expert Opin Ther Targets. 2012 Oct;16(10):985-97. doi: 10.1517/14728222.2012.712688. Epub 2012 Aug 10. Review.

PMID:
22880813
28.

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

Bollée G, Flamant M, Schordan S, Fligny C, Rumpel E, Milon M, Schordan E, Sabaa N, Vandermeersch S, Galaup A, Rodenas A, Casal I, Sunnarborg SW, Salant DJ, Kopp JB, Threadgill DW, Quaggin SE, Dussaule JC, Germain S, Mesnard L, Endlich K, Boucheix C, Belenfant X, Callard P, Endlich N, Tharaux PL.

Nat Med. 2011 Sep 25;17(10):1242-50. doi: 10.1038/nm.2491. Erratum in: Nat Med. 2011 Nov;17(11):1521. Nat Med. 2011 Oct;17(10):2 p following 1250.

29.

E-cadherin/p120-catenin and tetraspanin Co-029 cooperate for cell motility control in human colon carcinoma.

Greco C, Bralet MP, Ailane N, Dubart-Kupperschmitt A, Rubinstein E, Le Naour F, Boucheix C.

Cancer Res. 2010 Oct 1;70(19):7674-83. doi: 10.1158/0008-5472.CAN-09-4482. Epub 2010 Sep 21.

30.

alpha2beta1 integrin controls association of Rac with the membrane and triggers quiescence of endothelial cells.

Cailleteau L, Estrach S, Thyss R, Boyer L, Doye A, Domange B, Johnsson N, Rubinstein E, Boucheix C, Ebrahimian T, Silvestre JS, Lemichez E, Meneguzzi G, Mettouchi A.

J Cell Sci. 2010 Jul 15;123(Pt 14):2491-501. doi: 10.1242/jcs.058875.

31.

Tetraspanin CD81 is required for Listeria monocytogenes invasion.

Tham TN, Gouin E, Rubinstein E, Boucheix C, Cossart P, Pizarro-Cerda J.

Infect Immun. 2010 Jan;78(1):204-9. doi: 10.1128/IAI.00661-09. Epub 2009 Nov 9.

32.

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains.

Wakabayashi T, Craessaerts K, Bammens L, Bentahir M, Borgions F, Herdewijn P, Staes A, Timmerman E, Vandekerckhove J, Rubinstein E, Boucheix C, Gevaert K, De Strooper B.

Nat Cell Biol. 2009 Nov;11(11):1340-6. doi: 10.1038/ncb1978. Epub 2009 Oct 18.

PMID:
19838174
33.

The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection.

Charrin S, Yalaoui S, Bartosch B, Cocquerel L, Franetich JF, Boucheix C, Mazier D, Rubinstein E, Silvie O.

J Biol Chem. 2009 Nov 13;284(46):31572-8. doi: 10.1074/jbc.M109.057927. Epub 2009 Sep 17.

34.

In situ chemical cross-linking on living cells reveals CD9P-1 cis-oligomer at cell surface.

André M, Chambrion C, Charrin S, Soave S, Chaker J, Boucheix C, Rubinstein E, Le Naour F.

J Proteomics. 2009 Nov 2;73(1):93-102. doi: 10.1016/j.jprot.2009.08.005. Epub 2009 Aug 22.

PMID:
19703604
35.

A novel therapeutic strategy with anti-CD9 antibody in gastric cancers.

Nakamoto T, Murayama Y, Oritani K, Boucheix C, Rubinstein E, Nishida M, Katsube F, Watabe K, Kiso S, Tsutsui S, Tamura S, Shinomura Y, Hayashi N.

J Gastroenterol. 2009;44(9):889-96. doi: 10.1007/s00535-009-0081-3. Epub 2009 May 26.

PMID:
19468669
36.

Lateral organization of membrane proteins: tetraspanins spin their web.

Charrin S, le Naour F, Silvie O, Milhiet PE, Boucheix C, Rubinstein E.

Biochem J. 2009 May 13;420(2):133-54. doi: 10.1042/BJ20082422. Review.

PMID:
19426143
37.

CD9 negatively regulates integrin alphaIIbbeta3 activation and could thus prevent excessive platelet recruitment at sites of vascular injury.

Mangin PH, Kleitz L, Boucheix C, Gachet C, Lanza F.

J Thromb Haemost. 2009 May;7(5):900-2. doi: 10.1111/j.1538-7836.2009.03322.x. Epub 2009 Feb 18. No abstract available.

38.

Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor.

Arduise C, Abache T, Li L, Billard M, Chabanon A, Ludwig A, Mauduit P, Boucheix C, Rubinstein E, Le Naour F.

J Immunol. 2008 Nov 15;181(10):7002-13.

39.

Single-molecule analysis of CD9 dynamics and partitioning reveals multiple modes of interaction in the tetraspanin web.

Espenel C, Margeat E, Dosset P, Arduise C, Le Grimellec C, Royer CA, Boucheix C, Rubinstein E, Milhiet PE.

J Cell Biol. 2008 Aug 25;182(4):765-76. doi: 10.1083/jcb.200803010. Epub 2008 Aug 18.

40.

Genes contributing to prion pathogenesis.

Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB.

J Gen Virol. 2008 Jul;89(Pt 7):1777-88. doi: 10.1099/vir.0.2008/001255-0.

41.

Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis and/or at first relapse: results from the GET-LALA group.

Reman O, Pigneux A, Huguet F, Vey N, Delannoy A, Fegueux N, de Botton S, Stamatoullas A, Tournilhac O, Buzyn A, Charrin C, Boucheix C, Gabert J, Lhéritier V, Vernant JP, Fière D, Dombret H, Thomas X; GET-LALA group.

Leuk Res. 2008 Nov;32(11):1741-50. doi: 10.1016/j.leukres.2008.04.011. Epub 2008 May 27.

PMID:
18508120
42.

Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain.

Yalaoui S, Zougbédé S, Charrin S, Silvie O, Arduise C, Farhati K, Boucheix C, Mazier D, Rubinstein E, Froissard P.

PLoS Pathog. 2008 Feb 29;4(2):e1000010. doi: 10.1371/journal.ppat.1000010.

43.

Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial.

Tavernier E, Boiron JM, Huguet F, Bradstock K, Vey N, Kovacsovics T, Delannoy A, Fegueux N, Fenaux P, Stamatoullas A, Tournilhac O, Buzyn A, Reman O, Charrin C, Boucheix C, Gabert J, Lhéritier V, Vernant JP, Dombret H, Thomas X; GET-LALA Group; Swiss Group for Clinical Cancer Research SAKK; Australasian Leukaemia and Lymphoma Group.

Leukemia. 2007 Sep;21(9):1907-14. Epub 2007 Jul 5.

PMID:
17611565
44.

The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells.

Abache T, Le Naour F, Planchon S, Harper F, Boucheix C, Rubinstein E.

J Cell Biochem. 2007 Oct 15;102(3):650-64.

PMID:
17407154
45.

Alternative invasion pathways for Plasmodium berghei sporozoites.

Silvie O, Franetich JF, Boucheix C, Rubinstein E, Mazier D.

Int J Parasitol. 2007 Feb;37(2):173-82. Epub 2006 Oct 30.

PMID:
17112526
46.

Membrane microdomains and proteomics: lessons from tetraspanin microdomains and comparison with lipid rafts.

Le Naour F, André M, Boucheix C, Rubinstein E.

Proteomics. 2006 Dec;6(24):6447-54. Review.

PMID:
17109380
47.

Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience.

Picard C, Hayette S, Bilhou-Nabera C, Cayuela JM, Delabesse E, Frenoy N, Preudhomme C, Dupont M, Bastard C, Bories D, Vaerman JL, Davi F, Dastugue N, Raynaud S, Lafage M, Deschaseaux F, Fest T, Gaub MP, Lhéritier V, Thomas X, Charrin C, Boucheix C, Dombret H, Macintyre E, Fière D, Gabert J.

Leukemia. 2006 Dec;20(12):2178-81. Epub 2006 Oct 12. No abstract available.

PMID:
17039237
48.

Allogeneic stem cell transplantation improves the outcome of adults with t(1;19)/E2A-PBX1 and t(4;11)/MLL-AF4 positive B-cell acute lymphoblastic leukemia: results of the prospective multicenter LALA-94 study.

Vey N, Thomas X, Picard C, Kovascovicz T, Charin C, Cayuela JM, Dombret H, Dastugue N, Huguet F, Bastard C, Stamatoulas A, Giollant M, Tournilhac O, Macintyre E, Buzyn A, Bories D, Kuentz M, Dreyfus F, Delannoy A, Raynaud S, Gratecos N, Bordessoule D, de Botton S, Preudhomme C, Reman O, Troussard X, Pigneux A, Bilhou C, Vernant JP, Boucheix C, Gabert J; GET-LALA Group the Swiss Group for Clinical Cancer Research (SAKK).

Leukemia. 2006 Dec;20(12):2155-61. Epub 2006 Oct 12.

PMID:
17039234
49.

Expression of human CD81 differently affects host cell susceptibility to malaria sporozoites depending on the Plasmodium species.

Silvie O, Greco C, Franetich JF, Dubart-Kupperschmitt A, Hannoun L, van Gemert GJ, Sauerwein RW, Levy S, Boucheix C, Rubinstein E, Mazier D.

Cell Microbiol. 2006 Jul;8(7):1134-46.

PMID:
16819966
50.

Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites.

Silvie O, Charrin S, Billard M, Franetich JF, Clark KL, van Gemert GJ, Sauerwein RW, Dautry F, Boucheix C, Mazier D, Rubinstein E.

J Cell Sci. 2006 May 15;119(Pt 10):1992-2002.

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