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Items: 28


The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse.

Moui A, Klein M, Hassoun D, Dijoux E, Cheminant MA, Magnan A, Bouchaud G.

Respir Res. 2020 Jan 29;21(1):33. doi: 10.1186/s12931-020-1301-x.


Deamidation and Enzymatic Hydrolysis of Gliadins Alter Their Processing by Dendritic Cells in Vitro.

Villemin C, Tranquet O, Solé-Jamault V, Smit JJ, Pieters RHH, Denery-Papini S, Bouchaud G.

J Agric Food Chem. 2020 Feb 5;68(5):1447-1456. doi: 10.1021/acs.jafc.9b06075. Epub 2020 Jan 22.


Overview of in vivo and ex vivo endpoints in murine food allergy models: Suitable for evaluation of the sensitizing capacity of novel proteins?

Castan L, Bøgh KL, Maryniak NZ, Epstein MM, Kazemi S, O'Mahony L, Bodinier M, Smit JJ, van Bilsen JHM, Blanchard C, Głogowski R, Kozáková H, Schwarzer M, Noti M, de Wit N, Bouchaud G, Bastiaan-Net S.

Allergy. 2020 Feb;75(2):289-301. doi: 10.1111/all.13943. Epub 2019 Jul 9. Review.


[Allergen-derived peptide: A promising approach in asthma].

Klein M, Magnan A, Bouchaud G.

Rev Mal Respir. 2019 Apr;36(4):442-446. doi: 10.1016/j.rmr.2019.03.005. Epub 2019 Apr 18. Review. French.


[New protagonists in asthma pathophysiology].

Klein M, Dijoux E, Dilasser F, Hassoun D, Moui A, Loirand G, Colas L, Magnan A, Sauzeau V, Bouchaud G.

Presse Med. 2019 Mar;48(3 Pt 1):255-261. doi: 10.1016/j.lpm.2019.01.004. Epub 2019 Mar 8. Review. French.


CD9+ Regulatory B Cells Induce T Cell Apoptosis via IL-10 and Are Reduced in Severe Asthmatic Patients.

Brosseau C, Durand M, Colas L, Durand E, Foureau A, Cheminant MA, Bouchaud G, Castan L, Klein M, Magnan A, Brouard S.

Front Immunol. 2018 Dec 21;9:3034. doi: 10.3389/fimmu.2018.03034. eCollection 2018.


Piperidinyl-embeded chalcones possessing anti PI3Kδ inhibitory properties exhibit anti-atopic properties in preclinical models.

Dumontet C, Beck G, Gardebien F, Haudecoeur R, Mathé D, Matera EL, Tourette A, Mattei E, Esmenjaud J, Boyère C, Nurisso A, Peuchmaur M, Pérès B, Bouchaud G, Magnan A, Monneret G, Boumendjel A.

Eur J Med Chem. 2018 Oct 5;158:405-413. doi: 10.1016/j.ejmech.2018.09.033. Epub 2018 Sep 12.


Acid-Hydrolyzed Gliadins Worsen Food Allergies through Early Sensitization.

Castan L, Villemin C, Claude M, Aubert P, Durand T, Neunlist M, Brossard C, Magnan A, Bodinier M, Bouchaud G.

Mol Nutr Food Res. 2018 Sep;62(17):e1800159. doi: 10.1002/mnfr.201800159. Epub 2018 Jul 30.


Food allergen-sensitized CCR9+ lymphocytes enhance airways allergic inflammation in mice.

Castan L, Cheminant MA, Colas L, Brouard S, Magnan A, Bouchaud G.

Allergy. 2018 Jul;73(7):1505-1514. doi: 10.1111/all.13386. Epub 2018 Feb 20.


The β and α2δ auxiliary subunits of voltage-gated calcium channel 1 (Cav1) are required for TH2 lymphocyte function and acute allergic airway inflammation.

Rosa N, Triffaux E, Robert V, Mars M, Klein M, Bouchaud G, Canivet A, Magnan A, Guéry JC, Pelletier L, Savignac M.

J Allergy Clin Immunol. 2018 Sep;142(3):892-903.e8. doi: 10.1016/j.jaci.2017.09.045. Epub 2017 Nov 10.


How Proteins Aggregate Can Reduce Allergenicity: Comparison of Ovalbumins Heated under Opposite Electrostatic Conditions.

Claude M, Bouchaud G, Lupi R, Castan L, Tranquet O, Denery-Papini S, Bodinier M, Brossard C.

J Agric Food Chem. 2017 May 10;65(18):3693-3701. doi: 10.1021/acs.jafc.7b00676. Epub 2017 May 2.


Chemokine receptors in allergic diseases.

Castan L, Magnan A, Bouchaud G.

Allergy. 2017 May;72(5):682-690. doi: 10.1111/all.13089. Epub 2016 Dec 9. Review.


Endogenous polyclonal anti-IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation.

Spohn G, Arenas-Ramirez N, Bouchaud G, Boyman O.

J Allergy Clin Immunol. 2017 Jun;139(6):1957-1965.e3. doi: 10.1016/j.jaci.2016.09.033. Epub 2016 Nov 7.


Current challenges facing the assessment of the allergenic capacity of food allergens in animal models.

Bøgh KL, van Bilsen J, Głogowski R, López-Expósito I, Bouchaud G, Blanchard C, Bodinier M, Smit J, Pieters R, Bastiaan-Net S, de Wit N, Untersmayr E, Adel-Patient K, Knippels L, Epstein MM, Noti M, Nygaard UC, Kimber I, Verhoeckx K, O'Mahony L.

Clin Transl Allergy. 2016 Jun 16;6:21. doi: 10.1186/s13601-016-0110-2. eCollection 2016. Review.


The thermal aggregation of ovalbumin as large particles decreases its allergenicity for egg allergic patients and in a murine model.

Claude M, Lupi R, Bouchaud G, Bodinier M, Brossard C, Denery-Papini S.

Food Chem. 2016 Jul 15;203:136-144. doi: 10.1016/j.foodchem.2016.02.054. Epub 2016 Feb 10.


Maternal exposure to GOS/inulin mixture prevents food allergies and promotes tolerance in offspring in mice.

Bouchaud G, Castan L, Chesné J, Braza F, Aubert P, Neunlist M, Magnan A, Bodinier M.

Allergy. 2016 Jan;71(1):68-76. doi: 10.1111/all.12777. Epub 2015 Oct 26.


Consecutive Food and Respiratory Allergies Amplify Systemic and Gut but Not Lung Outcomes in Mice.

Bouchaud G, Gourbeyre P, Bihouée T, Aubert P, Lair D, Cheminant MA, Denery-Papini S, Neunlist M, Magnan A, Bodinier M.

J Agric Food Chem. 2015 Jul 22;63(28):6475-83. doi: 10.1021/acs.jafc.5b02338. Epub 2015 Jul 14.


Prevention of allergic asthma through Der p 2 peptide vaccination.

Bouchaud G, Braza F, Chesné J, Lair D, Chen KW, Rolland-Debord C, Hassoun D, Roussey-Bihouée T, Cheminant MA, Brouard S, Bodinier M, Vrtala S, Magnan A.

J Allergy Clin Immunol. 2015 Jul;136(1):197-200.e1. doi: 10.1016/j.jaci.2014.12.1938. Epub 2015 Feb 11. No abstract available.


Food allergy enhances allergic asthma in mice.

Bihouée T, Bouchaud G, Chesné J, Lair D, Rolland-Debord C, Braza F, Cheminant MA, Aubert P, Mahay G, Sagan C, Neunlist M, Brouard S, Bodinier M, Magnan A.

Respir Res. 2014 Nov 30;15:142. doi: 10.1186/s12931-014-0142-x.


Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer.

Rosalia RA, Arenas-Ramirez N, Bouchaud G, Raeber ME, Boyman O.

Curr Opin Chem Biol. 2014 Dec;23:39-46. doi: 10.1016/j.cbpa.2014.09.006. Epub 2014 Sep 29. Review.


Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.

Bouchaud G, Gehrke S, Krieg C, Kolios A, Hafner J, Navarini AA, French LE, Boyman O.

J Exp Med. 2013 Sep 23;210(10):2105-17. doi: 10.1084/jem.20130291. Epub 2013 Sep 9.


Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage.

Iolyeva M, Aebischer D, Proulx ST, Willrodt AH, Ecoiffier T, Häner S, Bouchaud G, Krieg C, Onder L, Ludewig B, Santambrogio L, Boyman O, Chen L, Finke D, Halin C.

Blood. 2013 Sep 26;122(13):2271-81. doi: 10.1182/blood-2013-01-478073. Epub 2013 Aug 20.


Cytokine complex-expanded natural killer cells improve allogeneic lung transplant function via depletion of donor dendritic cells.

Jungraithmayr W, Codarri L, Bouchaud G, Krieg C, Boyman O, Gyülvészi G, Becher B, Weder W, Münz C.

Am J Respir Crit Care Med. 2013 Jun 15;187(12):1349-59. doi: 10.1164/rccm.201209-1749OC.


Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation.

Perdreau H, Mortier E, Bouchaud G, Solé V, Boublik Y, Plet A, Jacques Y.

Eur Cytokine Netw. 2010 Dec;21(4):297-307. doi: 10.1684/ecn.2010.0207. Epub 2010 Nov 16.


Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease.

Bouchaud G, Mortier E, Flamant M, Barbieux I, Plet A, Galmiche JP, Jacques Y, Bourreille A.

Gastroenterology. 2010 Jun;138(7):2378-87. doi: 10.1053/j.gastro.2010.02.044. Epub 2010 Feb 23.


High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer.

Bessard A, Solé V, Bouchaud G, Quéméner A, Jacques Y.

Mol Cancer Ther. 2009 Sep;8(9):2736-45. doi: 10.1158/1535-7163.MCT-09-0275. Epub 2009 Sep 1.


The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.

Bouchaud G, Garrigue-Antar L, Solé V, Quéméner A, Boublik Y, Mortier E, Perdreau H, Jacques Y, Plet A.

J Mol Biol. 2008 Sep 26;382(1):1-12. doi: 10.1016/j.jmb.2008.07.019. Epub 2008 Jul 16.


The soluble alpha chain of interleukin-15 receptor: a proinflammatory molecule associated with tumor progression in head and neck cancer.

Badoual C, Bouchaud G, Agueznay Nel H, Mortier E, Hans S, Gey A, Fernani F, Peyrard S, -Puig PL, Bruneval P, Sastre X, Plet A, Garrigue-Antar L, Quintin-Colonna F, Fridman WH, Brasnu D, Jacques Y, Tartour E.

Cancer Res. 2008 May 15;68(10):3907-14. doi: 10.1158/0008-5472.CAN-07-6842.

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