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Items: 15

1.

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.

Ellis SJ, Lostchuck E, Goult BT, Bouaouina M, Fairchild MJ, López-Ceballos P, Calderwood DA, Tanentzapf G.

PLoS Genet. 2014 Nov 13;10(11):e1004756. doi: 10.1371/journal.pgen.1004756. eCollection 2014 Nov.

2.

Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.

Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR.

J Biol Chem. 2015 Jan 2;290(1):409-22. doi: 10.1074/jbc.M114.618421. Epub 2014 Nov 11.

3.

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.

Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC.

Development. 2014 Apr;141(7):1465-72. doi: 10.1242/dev.104539. Epub 2014 Mar 5.

4.

Zasp regulates integrin activation.

Bouaouina M, Jani K, Long JY, Czerniecki S, Morse EM, Ellis SJ, Tanentzapf G, Schöck F, Calderwood DA.

J Cell Sci. 2012 Dec 1;125(Pt 23):5647-57. doi: 10.1242/jcs.103291. Epub 2012 Sep 19.

5.

A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.

Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA.

J Biol Chem. 2012 Mar 2;287(10):6979-90. doi: 10.1074/jbc.M111.330845. Epub 2012 Jan 10.

6.

Talin and signaling through integrins.

Bouaouina M, Harburger DS, Calderwood DA.

Methods Mol Biol. 2012;757:325-47. doi: 10.1007/978-1-61779-166-6_20.

7.

The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain.

Razinia Z, Baldassarre M, Bouaouina M, Lamsoul I, Lutz PG, Calderwood DA.

J Cell Sci. 2011 Aug 1;124(Pt 15):2631-41. doi: 10.1242/jcs.084343. Epub 2011 Jul 12.

8.

Kindlins.

Bouaouina M, Calderwood DA.

Curr Biol. 2011 Feb 8;21(3):R99-101. doi: 10.1016/j.cub.2010.12.002. No abstract available.

9.

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.

Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL.

EMBO J. 2010 Mar 17;29(6):1069-80. doi: 10.1038/emboj.2010.4. Epub 2010 Feb 11.

10.

The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.

Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR.

J Mol Biol. 2009 Dec 18;394(5):944-56. doi: 10.1016/j.jmb.2009.09.061. Epub 2009 Oct 3.

11.

Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.

Harburger DS, Bouaouina M, Calderwood DA.

J Biol Chem. 2009 Apr 24;284(17):11485-97. doi: 10.1074/jbc.M809233200. Epub 2009 Feb 23.

12.

Prevalence of the metabolic syndrome among urban schoolchildren in Sousse, Tunisia.

Harrabi I, Bouaouina M, Maatoug J, Gaha R, Ghannem H.

Int J Cardiol. 2009 Jun 12;135(1):130-1. doi: 10.1016/j.ijcard.2008.01.035. Epub 2008 May 20.

PMID:
18495275
13.

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.

Bouaouina M, Lad Y, Calderwood DA.

J Biol Chem. 2008 Mar 7;283(10):6118-25. doi: 10.1074/jbc.M709527200. Epub 2007 Dec 28.

14.

Distinct signaling pathways are involved in leukosialin (CD43) down-regulation, membrane blebbing, and phospholipid scrambling during neutrophil apoptosis.

Nusbaum P, Lainé C, Bouaouina M, Seveau S, Cramer EM, Masse JM, Lesavre P, Halbwachs-Mecarelli L.

J Biol Chem. 2005 Feb 18;280(7):5843-53. Epub 2004 Dec 2.

15.

TNF-induced beta2 integrin activation involves Src kinases and a redox-regulated activation of p38 MAPK.

Bouaouina M, Blouin E, Halbwachs-Mecarelli L, Lesavre P, Rieu P.

J Immunol. 2004 Jul 15;173(2):1313-20.

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