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Items: 31


TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.

Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM.

Cell Rep. 2019 Jun 11;27(11):3269-3283.e6. doi: 10.1016/j.celrep.2019.05.040.


Mannose Receptor 1 Restricts HIV Particle Release from Infected Macrophages.

Sukegawa S, Miyagi E, Bouamr F, Farkašová H, Strebel K.

Cell Rep. 2018 Jan 16;22(3):786-795. doi: 10.1016/j.celrep.2017.12.085.


The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation.

Lee CP, Liu GT, Kung HN, Liu PT, Liao YT, Chow LP, Chang LS, Chang YH, Chang CW, Shu WC, Angers A, Farina A, Lin SF, Tsai CH, Bouamr F, Chen MR.

J Virol. 2016 Sep 29;90(20):8994-9007. doi: 10.1128/JVI.01235-16. Print 2016 Oct 15.


HIV-1 Nucleocapsid Mimics the Membrane Adaptor Syntenin PDZ to Gain Access to ESCRTs and Promote Virus Budding.

Sette P, O'Connor SK, Yerramilli VS, Dussupt V, Nagashima K, Chutiraka K, Lingappa J, Scarlata S, Bouamr F.

Cell Host Microbe. 2016 Mar 9;19(3):336-48. doi: 10.1016/j.chom.2016.02.004.


TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization.

Campbell EM, Weingart J, Sette P, Opp S, Sastri J, O'Connor SK, Talley S, Diaz-Griffero F, Hirsch V, Bouamr F.

J Virol. 2015 Dec 16;90(4):1849-57. doi: 10.1128/JVI.01948-15. Print 2016 Feb 15.


Ubiquitin conjugation to Gag is essential for ESCRT-mediated HIV-1 budding.

Sette P, Nagashima K, Piper RC, Bouamr F.

Retrovirology. 2013 Jul 29;10:79. doi: 10.1186/1742-4690-10-79.


Identification of the HIV-1 NC binding interface in Alix Bro1 reveals a role for RNA.

Sette P, Dussupt V, Bouamr F.

J Virol. 2012 Nov;86(21):11608-15. doi: 10.1128/JVI.01260-12. Epub 2012 Aug 15.


Two distinct binding modes define the interaction of Brox with the C-terminal tails of CHMP5 and CHMP4B.

Mu R, Dussupt V, Jiang J, Sette P, Rudd V, Chuenchor W, Bello NF, Bouamr F, Xiao TS.

Structure. 2012 May 9;20(5):887-98. doi: 10.1016/j.str.2012.03.001. Epub 2012 Apr 5.


Budding of retroviruses utilizing divergent L domains requires nucleocapsid.

Bello NF, Dussupt V, Sette P, Rudd V, Nagashima K, Bibollet-Ruche F, Chen C, Montelaro RC, Hahn BH, Bouamr F.

J Virol. 2012 Apr;86(8):4182-93. doi: 10.1128/JVI.07105-11. Epub 2012 Feb 15.


Virus budding/host interactions.

Harty RN, Schmitt AP, Bouamr F, Lopez CB, Krummenacher C.

Adv Virol. 2011;2011:963192. doi: 10.1155/2011/963192. Epub 2011 Oct 20. No abstract available.


The Phe105 loop of Alix Bro1 domain plays a key role in HIV-1 release.

Sette P, Mu R, Dussupt V, Jiang J, Snyder G, Smith P, Xiao TS, Bouamr F.

Structure. 2011 Oct 12;19(10):1485-95. doi: 10.1016/j.str.2011.07.016. Epub 2011 Sep 1.


Distal leucines are key functional determinants of Alix-binding simian immunodeficiency virus SIV(smE543) and SIV(mac239) type 3 L domains.

Bello NF, Wu F, Sette P, Dussupt V, Hirsch VM, Bouamr F.

J Virol. 2011 Nov;85(21):11532-7. doi: 10.1128/JVI.05284-11. Epub 2011 Aug 17.


Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding.

Dussupt V, Sette P, Bello NF, Javid MP, Nagashima K, Bouamr F.

J Virol. 2011 Mar;85(5):2304-15. doi: 10.1128/JVI.01562-10. Epub 2010 Dec 15.


The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif.

Sette P, Jadwin JA, Dussupt V, Bello NF, Bouamr F.

J Virol. 2010 Aug;84(16):8181-92. doi: 10.1128/JVI.00634-10. Epub 2010 Jun 2.


Late domain-independent rescue of a release-deficient Moloney murine leukemia virus by the ubiquitin ligase itch.

Jadwin JA, Rudd V, Sette P, Challa S, Bouamr F.

J Virol. 2010 Jan;84(2):704-15. doi: 10.1128/JVI.01319-09. Epub 2009 Oct 28.


The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral budding.

Dussupt V, Javid MP, Abou-Jaoudé G, Jadwin JA, de La Cruz J, Nagashima K, Bouamr F.

PLoS Pathog. 2009 Mar;5(3):e1000339. doi: 10.1371/journal.ppat.1000339. Epub 2009 Mar 13.


Solution NMR characterizations of oligomerization and dynamics of equine infectious anemia virus matrix protein and its interaction with PIP2.

Chen K, Bachtiar I, Piszczek G, Bouamr F, Carter C, Tjandra N.

Biochemistry. 2008 Feb 19;47(7):1928-37. doi: 10.1021/bi701984h. Epub 2008 Jan 26.


The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production.

Bouamr F, Houck-Loomis BR, De Los Santos M, Casaday RJ, Johnson MC, Goff SP.

J Virol. 2007 Mar;81(6):2909-22. Epub 2006 Dec 20.


The functionally exchangeable L domains in RSV and HIV-1 Gag direct particle release through pathways linked by Tsg101.

Medina G, Zhang Y, Tang Y, Gottwein E, Vana ML, Bouamr F, Leis J, Carter CA.

Traffic. 2005 Oct;6(10):880-94.


Structural and dynamics studies of the D54A mutant of human T cell leukemia virus-1 capsid protein.

Bouamr F, Cornilescu CC, Goff SP, Tjandra N, Carter CA.

J Biol Chem. 2005 Feb 25;280(8):6792-801. Epub 2004 Nov 29.


PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected].

Bouamr F, Melillo JA, Wang MQ, Nagashima K, de Los Santos M, Rein A, Goff SP.

J Virol. 2003 Nov;77(22):11882-95. Erratum in: J Virol. 2004 Apr;78(8):4383.


Role of myristylation in HIV-1 Gag assembly.

Bouamr F, Scarlata S, Carter C.

Biochemistry. 2003 Jun 3;42(21):6408-17.


Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells.

Kikonyogo A, Bouamr F, Vana ML, Xiang Y, Aiyar A, Carter C, Leis J.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11199-204. Epub 2001 Sep 18.


Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag).

VerPlank L, Bouamr F, LaGrassa TJ, Agresta B, Kikonyogo A, Leis J, Carter CA.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7724-9. Epub 2001 Jun 26.


Role of the major homology region in assembly of HIV-1 Gag.

Provitera P, Goff A, Harenberg A, Bouamr F, Carter C, Scarlata S.

Biochemistry. 2001 May 8;40(18):5565-72.


Structural analysis of the N-terminal domain of the human T-cell leukemia virus capsid protein.

Cornilescu CC, Bouamr F, Yao X, Carter C, Tjandra N.

J Mol Biol. 2001 Mar 2;306(4):783-97.


Differential budding efficiencies of human T-cell leukemia virus type I (HTLV-I) Gag and Gag-Pro polyproteins from insect and mammalian cells.

Bouamr F, Garnier L, Rayne F, Verna A, Rebeyrotte N, Cerutti M, Mamoun RZ.

Virology. 2000 Dec 20;278(2):597-609.


Binding of equine infectious anemia virus matrix protein to membrane bilayers involves multiple interactions.

Provitera P, Bouamr F, Murray D, Carter C, Scarlata S.

J Mol Biol. 2000 Feb 25;296(3):887-98.


Mouse monoclonal antibodies directed against the HTLV-I protease recognize epitopes internal to the dimer.

Mamoun RZ, Dye D, Rebeyrotte N, Bouamr F, Cerutti M, Desgranges C.

J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Feb 1;14(2):184-8.


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