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Antisense inhibition of lpxB gene expression in Acinetobacter baumannii by peptide-PNA conjugates and synergy with colistin.

Martínez-Guitián M, Vázquez-Ucha JC, Álvarez-Fraga L, Conde-Pérez K, Bou G, Poza M, Beceiro A.

J Antimicrob Chemother. 2019 Oct 5. pii: dkz409. doi: 10.1093/jac/dkz409. [Epub ahead of print]


Involvement of HisF in the Persistence of Acinetobacter baumannii During a Pneumonia Infection.

Martínez-Guitián M, Vázquez-Ucha JC, Álvarez-Fraga L, Conde-Pérez K, Lasarte-Monterrubio C, Vallejo JA, Bou G, Poza M, Beceiro A.

Front Cell Infect Microbiol. 2019 Aug 29;9:310. doi: 10.3389/fcimb.2019.00310. eCollection 2019.


Association between Pseudomonas aeruginosa O-antigen serotypes, resistance profiles and high-risk clones: results from a Spanish nationwide survey.

Del Barrio-Tofiño E, Sánchez-Diener I, Zamorano L, Cortes-Lara S, López-Causapé C, Cabot G, Bou G, Martínez-Martínez L, Oliver A; GEMARA-SEIMC/REIPI .

J Antimicrob Chemother. 2019 Nov 1;74(11):3217-3220. doi: 10.1093/jac/dkz346.


Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.

Vázquez-Ucha JC, Martínez-Guitián M, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, González-Bello C, Poza M, Beceiro A.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e01092-19. doi: 10.1128/AAC.01092-19. Print 2019 Oct.


Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone.

Arca-Suárez J, Fraile-Ribot P, Vázquez-Ucha JC, Cabot G, Martínez-Guitián M, Lence E, González-Bello C, Beceiro A, Rodríguez-Iglesias M, Galán-Sánchez F, Bou G, Oliver A.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e01110-19. doi: 10.1128/AAC.01110-19. Print 2019 Oct.


Quorum and Light Signals Modulate Acetoin/Butanediol Catabolism in Acinetobacter spp.

Tuttobene MR, Fernández-García L, Blasco L, Cribb P, Ambroa A, Müller GL, Fernández-Cuenca F, Bleriot I, Rodríguez RE, Barbosa BGV, Lopez-Rojas R, Trastoy R, López M, Bou G, Tomás M, Mussi MA.

Front Microbiol. 2019 Jun 20;10:1376. doi: 10.3389/fmicb.2019.01376. eCollection 2019.


Relationship Between Quorum Sensing and Secretion Systems.

Pena RT, Blasco L, Ambroa A, González-Pedrajo B, Fernández-García L, López M, Bleriot I, Bou G, García-Contreras R, Wood TK, Tomás M.

Front Microbiol. 2019 Jun 7;10:1100. doi: 10.3389/fmicb.2019.01100. eCollection 2019. Review.


Multiplex Real-Time PCR-shortTUB Assay for Detection of the Mycobacterium tuberculosis Complex in Smear-Negative Clinical Samples with Low Mycobacterial Loads.

Alcaide F, Trastoy R, Moure R, González-Bardanca M, Ambroa A, López M, Bleriot I, Blasco L, Fernandez-García L, Tato M, Bou G, Tomás M; Mycobacterial and GEMARA SEIMC/REIPI Bacterial Clinical Adaptation Study Group.

J Clin Microbiol. 2019 Jul 26;57(8). pii: e00733-19. doi: 10.1128/JCM.00733-19. Print 2019 Aug.


Spanish nationwide survey on Pseudomonas aeruginosa antimicrobial resistance mechanisms and epidemiology.

Del Barrio-Tofiño E, Zamorano L, Cortes-Lara S, López-Causapé C, Sánchez-Diener I, Cabot G, Bou G, Martínez-Martínez L, Oliver A; GEMARA-SEIMC/REIPI Pseudomonas study Group .

J Antimicrob Chemother. 2019 Jul 1;74(7):1825-1835. doi: 10.1093/jac/dkz147.


Identification of piRNAs and piRNA clusters in the testes of the Mongolian horse.

Li B, He X, Zhao Y, Bai D, Bou G, Zhang X, Su S, Dao L, Liu R, Wang Y, Manglai D.

Sci Rep. 2019 Mar 22;9(1):5022. doi: 10.1038/s41598-019-41475-9.


Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems.

Cantón R, Oliver A, Alós JI, de Benito N, Bou G, Campos J, Calvo J, Canut A, Castillo J, Cercenado E, Domínguez MÁ, Fernández-Cuenca F, Guinea J, Larrosa N, Liñares J, López-Cerero L, López-Navas A, Marco F, Mirelis B, Moreno-Romo MÁ, Morosini MI, Navarro F, Oteo J, Pascual Á, Pérez-Trallero E, Pérez-Vázquez M, Soriano A, Torres C, Vila J, Martínez-Martínez L.

Enferm Infecc Microbiol Clin. 2019 Mar 13. pii: S0213-005X(19)30135-1. doi: 10.1016/j.eimc.2019.01.017. [Epub ahead of print] Review. English, Spanish.


In Vitro and In Vivo Activities of β-Lactams in Combination with the Novel β-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-β-Lactamase-Producing Klebsiella pneumoniae.

Moya B, Barcelo IM, Cabot G, Torrens G, Palwe S, Joshi P, Umarkar K, Takalkar S, Periasamy H, Bhagwat S, Patel M, Bou G, Oliver A.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00128-19. doi: 10.1128/AAC.00128-19. Print 2019 May.


Activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and Enterobacterales isolates recovered from intensive care unit patients in Spain: The SUPERIOR multicentre study.

García-Fernández S, García-Castillo M, Bou G, Calvo J, Cercenado E, Delgado M, Pitart C, Mulet X, Tormo N, Mendoza DL, Díaz-Regañón J, Cantón R; SUPERIOR Study Group.

Int J Antimicrob Agents. 2019 May;53(5):682-688. doi: 10.1016/j.ijantimicag.2019.02.004. Epub 2019 Feb 12.


High incidence of MDR and XDR Pseudomonas aeruginosa isolates obtained from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial.

Pérez A, Gato E, Pérez-Llarena J, Fernández-Cuenca F, Gude MJ, Oviaño M, Pachón ME, Garnacho J, González V, Pascual Á, Cisneros JM, Bou G.

J Antimicrob Chemother. 2019 May 1;74(5):1244-1252. doi: 10.1093/jac/dkz030.


Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii.

Fernandez-Garcia L, Ambroa A, Blasco L, Bleriot I, López M, Alvarez-Marin R, Fernández-Cuenca F, Martinez-Martinez L, Vila J, Rodríguez-Baño J, Garnacho-Montero J, Cisneros JM, Pascual A, Pachón J, Bou G, Smani Y, Tomás M.

Front Microbiol. 2018 Dec 17;9:3105. doi: 10.3389/fmicb.2018.03105. eCollection 2018.


Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for the Rapid Detection of Antimicrobial Resistance Mechanisms and Beyond.

Oviaño M, Bou G.

Clin Microbiol Rev. 2018 Nov 28;32(1). pii: e00037-18. doi: 10.1128/CMR.00037-18. Print 2019 Jan. Review.


Fetal bovine serum promotes the development of in vitro porcine blastocysts by activating the Rho-associated kinase signalling pathway.

Guo S, Liu S, Bou G, Guo J, Jiang L, Chai Z, Cai M, Mu Y, Liu Z.

Reprod Fertil Dev. 2019 Jan;31(2):366-376. doi: 10.1071/RD18070.


Mechanisms of Bacterial Tolerance and Persistence in the Gastrointestinal and Respiratory Environments.

Trastoy R, Manso T, Fernández-García L, Blasco L, Ambroa A, Pérez Del Molino ML, Bou G, García-Contreras R, Wood TK, Tomás M.

Clin Microbiol Rev. 2018 Aug 1;31(4). pii: e00023-18. doi: 10.1128/CMR.00023-18. Print 2018 Oct. Review.


Predictors of outcome in patients with severe sepsis or septic shock due to extended-spectrum β-lactamase-producing Enterobacteriaceae.

Russo A, Falcone M, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale PL, Oliver A, Ruiz-Garbajosa P, Gasch O, Gozalo M, Pitout J, Akova M, Peña C, Cisneros JM, Hernández-Torres A, Farcomeni A, Prim N, Origüen J, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Karaiskos I, de la Calle C, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Mora-Rillo M, Rodriguez-Gomez J, Souli M, Bonomo RA, Paterson DL, Carmeli Y, Pascual A, Rodríguez-Baño J, Venditti M; REIPI/ESGBIS/INCREMENT investigators.

Int J Antimicrob Agents. 2018 Nov;52(5):577-585. doi: 10.1016/j.ijantimicag.2018.06.018. Epub 2018 Jun 30.


Current aspects in sepsis approach. Turning things around.

Candel FJ, Borges Sá M, Belda S, Bou G, Del Pozo JL, Estrada O, Ferrer R, González Del Castillo J, Julián-Jiménez A, Martín-Loeches I, Maseda E, Matesanz M, Ramírez P, Ramos JT, Rello J, Suberviola B, Suárez de la Rica A, Vidal P.

Rev Esp Quimioter. 2018 Aug;31(4):298-315. Epub 2018 Jun 25. Review.


[Overview of the genetic control of horse coat color patterns].

Zhao RY, Zhao YP, Li B, Bou G, Zhang XZ, Mongke T, Bao T, Gereliin S, Gereltuuin T, Li C, Bai DY, Dugarjaviin ML.

Yi Chuan. 2018 May 20;40(5):357-368. doi: 10.16288/j.yczz.17-371. Review. Chinese.


Asynchronous CDX2 expression and polarization of porcine trophoblast cells reflects a species-specific trophoderm lineage determination progress model.

Liu S, Bou G, Zhao J, Guo S, Guo J, Weng X, Yin Z, Liu Z.

Mol Reprod Dev. 2018 Jul;85(7):590-598. doi: 10.1002/mrd.22994. Epub 2018 Jul 16.


Comparison of Predictors and Mortality Between Bloodstream Infections Caused by ESBL-Producing Escherichia coli and ESBL-Producing Klebsiella pneumoniae.

Scheuerman O, Schechner V, Carmeli Y, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale PL, Oliver A, Ruiz-Garbajosa P, Gasch O, Gozalo M, Pitout J, Akova M, Peña C, Molina J, Hernández-Torres A, Venditti M, Prim N, Origüen J, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Karaiskos I, de la Calle C, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Navarro-San Francisco C, Bonomo RA, Paterson DL, Pascual A, Rodríguez-Baño J; REIPI/ESGBIS/INCREMENT investigators.

Infect Control Hosp Epidemiol. 2018 Jun;39(6):660-667. doi: 10.1017/ice.2018.63. Epub 2018 Apr 5.


Rapid Determination of Resistance to Antibiotic Inhibitors of Protein Synthesis in Staphylococcus aureus Through In Situ Evaluation of DNase Activity.

Otero F, Santiso R, López I, Touzón I, Gosálvez J, Bou G, Fernández JL.

Microb Drug Resist. 2018 Jul/Aug;24(6):739-746. doi: 10.1089/mdr.2018.0023. Epub 2018 Apr 2.


Reporting identification of Acinetobacter spp genomic species: A nationwide proficiency study in Spain.

Fernández-Cuenca F, Tomás M, Tormo N, Gimeno C, Bou G, Pascual Á.

Enferm Infecc Microbiol Clin. 2019 Feb;37(2):89-92. doi: 10.1016/j.eimc.2018.02.004. Epub 2018 Mar 28. English, Spanish.


Draft Genome Sequences of Two Epidemic OXA-48-Producing Klebsiella pneumoniae Clinical Strains Isolated during a Large Outbreak in Spain.

Gato E, Álvarez-Fraga L, Vallejo JA, Rumbo-Feal S, Martínez-Guitián M, Beceiro A, Poza M, Bou G, Pérez A.

Genome Announc. 2018 Mar 29;6(13). pii: e00026-18. doi: 10.1128/genomeA.00026-18.


Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa: Guidelines by the Spanish Society of Chemotherapy.

Mensa J, Barberán J, Soriano A, Llinares P, Marco F, Cantón R, Bou G, González Del Castillo J, Maseda E, Azanza JR, Pasquau J, García-Vidal C, Reguera JM, Sousa D, Gómez J, Montejo M, Borges M, Torres A, Alvarez-Lerma F, Salavert M, Zaragoza R, Oliver A.

Rev Esp Quimioter. 2018 Feb;31(1):78-100. Epub 2018 Feb 23. Review.


Relationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System.

Fernández-García L, Fernandez-Cuenca F, Blasco L, López-Rojas R, Ambroa A, Lopez M, Pascual Á, Bou G, Tomás M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00250-18. doi: 10.1128/AAC.00250-18. Print 2018 May.


Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade.

López M, Rueda A, Florido JP, Blasco L, Fernández-García L, Trastoy R, Fernández-Cuenca F, Martínez-Martínez L, Vila J, Pascual A, Bou G, Tomas M.

Sci Rep. 2018 Feb 6;8(1):2523. doi: 10.1038/s41598-018-20847-7.


Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii.

Álvarez-Fraga L, Vázquez-Ucha JC, Martínez-Guitián M, Vallejo JA, Bou G, Beceiro A, Poza M.

Virulence. 2018 Jan 1;9(1):496-509. doi: 10.1080/21505594.2017.1420451.


A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus.

Moscoso M, García P, Cabral MP, Rumbo C, Bou G.

Virulence. 2018 Jan 1;9(1):604-620. doi: 10.1080/21505594.2017.1417723.


Reporting antimicrobial susceptibilities and resistance phenotypes in Acinetobacter spp: a nationwide proficiency study.

Fernández-Cuenca F, Tomás M, Caballero-Moyano FJ, Bou G, Pascual Á; Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC).

J Antimicrob Chemother. 2018 Mar 1;73(3):692-697. doi: 10.1093/jac/dkx464.


How to: identify non-tuberculous Mycobacterium species using MALDI-TOF mass spectrometry.

Alcaide F, Amlerová J, Bou G, Ceyssens PJ, Coll P, Corcoran D, Fangous MS, González-Álvarez I, Gorton R, Greub G, Hery-Arnaud G, Hrábak J, Ingebretsen A, Lucey B, Marekoviċ I, Mediavilla-Gradolph C, Monté MR, O'Connor J, O'Mahony J, Opota O, O'Reilly B, Orth-Höller D, Oviaño M, Palacios JJ, Palop B, Pranada AB, Quiroga L, Rodríguez-Temporal D, Ruiz-Serrano MJ, Tudó G, Van den Bossche A, van Ingen J, Rodriguez-Sanchez B; European Study Group on Genomics and Molecular Diagnosis (ESGMD).

Clin Microbiol Infect. 2018 Jun;24(6):599-603. doi: 10.1016/j.cmi.2017.11.012. Epub 2017 Nov 22. Review.


Quantitative and automated MALDI-TOF MS-based detection of the plasmid-mediated quinolone resistance determinant AAC(6')-Ib-cr in Enterobacteriaceae.

Oviaño M, Gómara M, Barba MJ, Sparbier K, Pascual Á, Bou G.

J Antimicrob Chemother. 2017 Oct 1;72(10):2952-2954. doi: 10.1093/jac/dkx218. No abstract available.


Empiric Therapy With Carbapenem-Sparing Regimens for Bloodstream Infections due to Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: Results From the INCREMENT Cohort.

Palacios-Baena ZR, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale P, Oliver A, Pintado V, Gasch O, Martínez-Martínez L, Pitout J, Akova M, Peña C, Molina Gil-Bermejo J, Hernández A, Venditti M, Prim N, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Giamarellou H, Almela M, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Paño-Pardo JR, Torre-Cisneros J, Souli M, Bonomo RA, Carmeli Y, Paterson DL, Pascual Á, Rodríguez-Baño J; Spanish Network for Research in Infectious Diseases (REIPI)/European Study Group of Bloodstream Infections and Sepsis (ESGBIS)/INCREMENT Group.

Clin Infect Dis. 2017 Oct 30;65(10):1615-1623. doi: 10.1093/cid/cix606.


Direct identification of clinical pathogens from liquid culture media by MALDI-TOF MS analysis.

Oviaño M, Rodríguez-Sánchez B, Gómara M, Alcalá L, Zvezdanova E, Ruíz A, Velasco D, Gude MJ, Bouza E, Bou G.

Clin Microbiol Infect. 2018 Jun;24(6):624-629. doi: 10.1016/j.cmi.2017.09.010. Epub 2017 Sep 27.


Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates.

Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01238-17. doi: 10.1128/AAC.01238-17. Print 2017 Nov.


Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii.

Vázquez-Ucha JC, Maneiro M, Martínez-Guitián M, Buynak J, Bethel CR, Bonomo RA, Bou G, Poza M, González-Bello C, Beceiro A.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01172-17. doi: 10.1128/AAC.01172-17. Print 2017 Nov.


Global assessment of small RNAs reveals a non-coding transcript involved in biofilm formation and attachment in Acinetobacter baumannii ATCC 17978.

Álvarez-Fraga L, Rumbo-Feal S, Pérez A, Gómez MJ, Gayoso C, Vallejo JA, Ohneck EJ, Valle J, Actis LA, Beceiro A, Bou G, Poza M.

PLoS One. 2017 Aug 1;12(8):e0182084. doi: 10.1371/journal.pone.0182084. eCollection 2017.


Rapid Detection of Bacterial Susceptibility or Resistance to Quinolones.

Otero F, Santiso R, Tamayo M, Bou G, Gosálvez J, Fernández JL.

Methods Mol Biol. 2017;1644:95-104. doi: 10.1007/978-1-4939-7187-9_7.


Increased Antimicrobial Resistance in a Novel CMY-54 AmpC-Type Enzyme with a GluLeu217-218 Insertion in the Ω-Loop.

Pérez-Llarena FJ, Vázquez-Ucha JC, Kerff F, Zamorano L, Miró E, Cabral MP, Fleites A, Lantero M, Martínez-Martínez L, Oliver A, Galleni M, Navarro F, Beceiro A, Bou G.

Microb Drug Resist. 2018 Jun;24(5):527-533. doi: 10.1089/mdr.2017.0017. Epub 2017 Jun 30.


Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy.

Cabral MP, García P, Beceiro A, Rumbo C, Pérez A, Moscoso M, Bou G.

Nat Commun. 2017 May 26;8:15480. doi: 10.1038/ncomms15480.


Response to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing.

López M, Blasco L, Gato E, Perez A, Fernández-Garcia L, Martínez-Martinez L, Fernández-Cuenca F, Rodríguez-Baño J, Pascual A, Bou G, Tomás M.

Front Cell Infect Microbiol. 2017 May 9;7:143. doi: 10.3389/fcimb.2017.00143. eCollection 2017.


Mutations in the β-Subunit of the RNA Polymerase Impair the Surface-Associated Motility and Virulence of Acinetobacter baumannii.

Pérez-Varela M, Corral J, Vallejo JA, Rumbo-Feal S, Bou G, Aranda J, Barbé J.

Infect Immun. 2017 Jul 19;85(8). pii: e00327-17. doi: 10.1128/IAI.00327-17. Print 2017 Aug.


Simple and Fast Detection of Resistance to Antibiotic Inhibitors of Protein Synthesis in Gram-Negative Pathogens Through Evaluation of Mitomycin C-Induced Cell Elongation.

Otero F, Gosálvez J, Bou G, Fernández JL.

Microb Drug Resist. 2017 Dec;23(8):973-981. doi: 10.1089/mdr.2017.0028. Epub 2017 May 3.


Overproduction of Outer Membrane Protein A by Acinetobacter baumannii as a Risk Factor for Nosocomial Pneumonia, Bacteremia, and Mortality Rate Increase.

Sánchez-Encinales V, Álvarez-Marín R, Pachón-Ibáñez ME, Fernández-Cuenca F, Pascual A, Garnacho-Montero J, Martínez-Martínez L, Vila J, Tomás MM, Cisneros JM, Bou G, Rodríguez-Baño J, Pachón J, Smani Y.

J Infect Dis. 2017 Mar 15;215(6):966-974. doi: 10.1093/infdis/jix010.


Towards the early detection of β-lactamase-producing Enterobacteriaceae by MALDI-TOF MS analysis.

Oviaño M, Gómara M, Barba MJ, Revillo MJ, Barbeyto LP, Bou G.

J Antimicrob Chemother. 2017 Aug 1;72(8):2259-2262. doi: 10.1093/jac/dkx127.


Contribution of the A. baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence.

Rumbo-Feal S, Pérez A, Ramelot TA, Álvarez-Fraga L, Vallejo JA, Beceiro A, Ohneck EJ, Arivett BA, Merino M, Fiester SE, Kennedy MA, Actis LA, Bou G, Poza M.

Front Cell Infect Microbiol. 2017 Apr 3;7:108. doi: 10.3389/fcimb.2017.00108. eCollection 2017.


Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme.

López M, Mayer C, Fernández-García L, Blasco L, Muras A, Ruiz FM, Bou G, Otero A, Tomás M; GEIH-GEMARA (SEIMC).

PLoS One. 2017 Mar 22;12(3):e0174454. doi: 10.1371/journal.pone.0174454. eCollection 2017.


WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones.

Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02529-16. doi: 10.1128/AAC.02529-16. Print 2017 Jun.

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