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Paediatric acute kidney injury hospital admissions in England 1997-2014: burden and risk factors.

Henderson A, Iwagami M, Bottomley C, Tomlinson L, Mansfield K, Nitsch D.

Clin Kidney J. 2019 Jun 7;12(6):859-860. doi: 10.1093/ckj/sfz075. eCollection 2019 Dec. No abstract available.


Challenges and opportunities in evaluating programmes incorporating human-centred design: lessons learnt from the evaluation of Adolescents 360.

Doyle AM, Mulhern E, Rosen J, Appleford G, Atchison C, Bottomley C, Hargreaves JR, Weinberger M.

Version 2. Gates Open Res. 2019 Sep 25 [revised 2019 Jan 1];3:1472. doi: 10.12688/gatesopenres.12998.2. eCollection 2019.


Impact of the introduction of rotavirus vaccine on hospital admissions for diarrhoea among children in Kenya: A controlled interrupted time series analysis.

Otieno GP, Bottomley C, Khagayi S, Adetifa I, Ngama M, Omore R, Ogwel B, Owor BE, Bigogo G, Ochieng JB, Onyango C, Juma J, Mwenda J, Tabu C, Tate JE, Addo Y, Britton T, Parashar UD, Breiman RF, Verani JR, Nokes DJ.

Clin Infect Dis. 2019 Sep 23. pii: ciz912. doi: 10.1093/cid/ciz912. [Epub ahead of print]


Modern contraceptive use among sexually active women aged 15-19 years in North-Western Tanzania: results from the Adolescent 360 (A360) baseline survey.

Nsanya MK, Atchison CJ, Bottomley C, Doyle AM, Kapiga SH.

BMJ Open. 2019 Aug 28;9(8):e030485. doi: 10.1136/bmjopen-2019-030485.


Genomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin.

Bojang A, Baines SL, Donovan L, Guerillot R, Stevens K, Higgs C, Bottomley C, Secka O, Schultz MB, Gonçalves da Silva A, Seemann T, Stinear TP, Roca A, Howden BP.

J Antimicrob Chemother. 2019 Nov 1;74(11):3170-3178. doi: 10.1093/jac/dkz341.


Triaging women with pregnancy of unknown location using two-step protocol including M6 model: clinical implementation study.

Bobdiwala S, Christodoulou E, Farren J, Mitchell-Jones N, Kyriacou C, Al-Memar M, Ayim F, Chohan B, Kirk E, Abughazza O, Guruwadahyarhalli B, Guha S, Vathanan V, Bottomley C, Gould D, Stalder C, Timmerman D, van Calster B, Bourne T.

Ultrasound Obstet Gynecol. 2020 Jan;55(1):105-114. doi: 10.1002/uog.20420.


Cryptococcal meningitis screening and community-based early adherence support in people with advanced HIV infection starting antiretroviral therapy in Tanzania and Zambia: a cost-effectiveness analysis.

Kimaro GD, Guinness L, Shiri T, Kivuyo S, Chanda D, Bottomley C, Chen T, Kahwa A, Hawkins N, Mwaba P, Mfinanga SG, Harrison TS, Jaffar S, Niessen LW.

Clin Infect Dis. 2019 May 31. pii: ciz453. doi: 10.1093/cid/ciz453. [Epub ahead of print]


Effect of strikes by health workers on mortality between 2010 and 2016 in Kilifi, Kenya: a population-based cohort analysis.

Ong'ayo G, Ooko M, Wang'ondu R, Bottomley C, Nyaguara A, Tsofa BK, Williams TN, Bejon P, Scott JAG, Etyang AO.

Lancet Glob Health. 2019 Jul;7(7):e961-e967. doi: 10.1016/S2214-109X(19)30188-3. Epub 2019 May 22.


A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy.

Coomarasamy A, Devall AJ, Cheed V, Harb H, Middleton LJ, Gallos ID, Williams H, Eapen AK, Roberts T, Ogwulu CC, Goranitis I, Daniels JP, Ahmed A, Bender-Atik R, Bhatia K, Bottomley C, Brewin J, Choudhary M, Crosfill F, Deb S, Duncan WC, Ewer A, Hinshaw K, Holland T, Izzat F, Johns J, Kriedt K, Lumsden MA, Manda P, Norman JE, Nunes N, Overton CE, Quenby S, Rao S, Ross J, Shahid A, Underwood M, Vaithilingam N, Watkins L, Wykes C, Horne A, Jurkovic D.

N Engl J Med. 2019 May 9;380(19):1815-1824. doi: 10.1056/NEJMoa1813730.


Effect of morphological type of extrauterine ectopic pregnancy on accuracy of preoperative ultrasound diagnosis.

Dooley WM, Chaggar P, De Braud LV, Bottomley C, Jauniaux E, Jurkovic D.

Ultrasound Obstet Gynecol. 2019 Oct;54(4):538-544. doi: 10.1002/uog.20274. Epub 2019 Sep 6.


A mixed methods analysis of factors affecting antenatal care content: A Syrian case study.

Mourtada R, Bottomley C, Houben F, Bashour H, Campbell OMR.

PLoS One. 2019 Mar 25;14(3):e0214375. doi: 10.1371/journal.pone.0214375. eCollection 2019.


Staphylococcus aureus Bacteremia in Children of Rural Areas of The Gambia, 2008-2015.

Odutola A, Bottomley C, Zaman SA, Lindsay J, Shah M, Hossain I, Ndiaye M, Osuorah CDI, Olatunji Y, Badji H, Ikumapayi UNA, Manjang A, Salaudeen R, Ceesay L, Jasseh M, Adegbola RA, Corrah T, Hill PC, Greenwood BM, Mackenzie GA.

Emerg Infect Dis. 2019 Apr;25(4):701-709. doi: 10.3201/eid2504.180935.


Carriage and Acquisition of Extended-spectrum β-Lactamase-producing Enterobacterales Among Neonates Admitted to Hospital in Kilifi, Kenya.

Kagia N, Kosgei P, Ooko M, Wafula L, Mturi N, Anampiu K, Mwarumba S, Njuguna P, Seale AC, Berkley JA, Bottomley C, Scott JAG, Morpeth SC.

Clin Infect Dis. 2019 Aug 16;69(5):751-759. doi: 10.1093/cid/ciy976.


Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis.

Silaba M, Ooko M, Bottomley C, Sande J, Benamore R, Park K, Ignas J, Maitland K, Mturi N, Makumi A, Otiende M, Kagwanja S, Safari S, Ochola V, Bwanaali T, Bauni E, Gleeson F, Deloria Knoll M, Adetifa I, Marsh K, Williams TN, Kamau T, Sharif S, Levine OS, Hammitt LL, Scott JAG.

Lancet Glob Health. 2019 Mar;7(3):e337-e346. doi: 10.1016/S2214-109X(18)30491-1.


Sexuality, fertility and family planning characteristics of married women aged 15 to 19 years in Ethiopia, Nigeria and Tanzania: a comparative analysis of cross-sectional data.

Atchison CJ, Cresswell JA, Kapiga S, Nsanya MK, Crawford EE, Mussa M, Bottomley C, Hargreaves JR, Doyle AM.

Reprod Health. 2019 Jan 21;16(1):6. doi: 10.1186/s12978-019-0666-0.


A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol.

May J, Duncan C, Mol B, Bhattacharya S, Daniels J, Middleton L, Hewitt C, Coomarasamy A, Jurkovic D, Bourne T, Bottomley C, Peace-Gadsby A, Doust A, Tong S, Horne AW.

Trials. 2018 Nov 20;19(1):643. doi: 10.1186/s13063-018-3008-6.


Long-lasting effect of oral azithromycin taken by women during labour on infant nutrition: Follow-up cohort of a randomized clinical trial in western Gambia.

Roca A, Camara B, Oluwalana C, Lette K, Bottomley C, D'Alessandro U.

PLoS One. 2018 Oct 25;13(10):e0206348. doi: 10.1371/journal.pone.0206348. eCollection 2018.


Persistence of Nasopharyngeal Pneumococcal Vaccine Serotypes and Increase of Nonvaccine Serotypes Among Vaccinated Infants and Their Mothers 5 Years After Introduction of Pneumococcal Conjugate Vaccine 13 in The Gambia.

Usuf E, Bottomley C, Bojang E, Cox I, Bojang A, Gladstone R, Kampmann B, Hill PC, Roca A.

Clin Infect Dis. 2019 Apr 24;68(9):1512-1521. doi: 10.1093/cid/ciy726.


Relationship between Anaemia, Haemolysis, Inflammation and Haem Oxygenase-1 at Admission with Sepsis: a pilot study.

Ekregbesi P, Shankar-Hari M, Bottomley C, Riley EM, Mooney JP.

Sci Rep. 2018 Jul 25;8(1):11198. doi: 10.1038/s41598-018-29558-5.


Reliability and validity of the World Health Organization reading standards for paediatric chest radiographs used in the field in an impact study of Pneumococcal Conjugate Vaccine in Kilifi, Kenya.

Ominde M, Sande J, Ooko M, Bottomley C, Benamore R, Park K, Ignas J, Maitland K, Bwanaali T, Gleeson F, Scott A.

PLoS One. 2018 Jul 25;13(7):e0200715. doi: 10.1371/journal.pone.0200715. eCollection 2018.


Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan children.

Morpeth SC, Munywoki P, Hammitt LL, Bett A, Bottomley C, Onyango CO, Murdoch DR, Nokes DJ, Scott JAG.

Sci Rep. 2018 Jul 23;8(1):11030. doi: 10.1038/s41598-018-29119-w.


Haemolysis and haem oxygenase-1 induction during persistent "asymptomatic" malaria infection in Burkinabé children.

Mooney JP, Barry A, Gonçalves BP, Tiono AB, Awandu SS, Grignard L, Drakeley CJ, Bottomley C, Bousema T, Riley EM.

Malar J. 2018 Jul 6;17(1):253. doi: 10.1186/s12936-018-2402-6.


Imaging of acute abdominal pain in the third trimester of pregnancy.

Shur J, Bottomley C, Walton K, Patel JH.

BMJ. 2018 Jun 21;361:k2511. doi: 10.1136/bmj.k2511. No abstract available.


Evaluating the impact of an intervention to increase uptake of modern contraceptives among adolescent girls (15-19 years) in Nigeria, Ethiopia and Tanzania: the Adolescents 360 quasi-experimental study protocol.

Atchison CJ, Mulhern E, Kapiga S, Nsanya MK, Crawford EE, Mussa M, Bottomley C, Hargreaves JR, Doyle AM.

BMJ Open. 2018 May 31;8(5):e021834. doi: 10.1136/bmjopen-2018-021834.


Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial.

Howie S, Bottomley C, Chimah O, Ideh R, Ebruke B, Okomo U, Onyeama C, Donkor S, Rodrigues O, Tapgun M, Janneh M, Oluwalana C, Kuti B, Enwere G, Esangbedo P, Doherty C, Mackenzie G, Greenwood B, Corrah T, Prentice A, Adegbola R, Zaman S.

J Glob Health. 2018 Jun;8(1):010418. doi: 10.7189/jogh.08.010418.


Caesarean scar pregnancy in the UK: a national cohort study.

Harb HM, Knight M, Bottomley C, Overton C, Tobias A, Gallos ID, Shehmar M, Farquharson R, Horne A, Latthe P, Edi-Osagie E, MacLean M, Marston E, Zamora J, Dawood F, Small R, Ross J, Bourne T, Coomarasamy A, Jurkovic D.

BJOG. 2018 Dec;125(13):1663-1670. doi: 10.1111/1471-0528.15255. Epub 2018 Jun 5.


Long-term Impact of Oral Azithromycin Taken by Gambian Women During Labor on Prevalence and Antibiotic Susceptibility of Streptococcus pneumoniae and Staphylococcus aureus in Their Infants: Follow-up of a Randomized Clinical Trial.

Bojang A, Camara B, Jagne Cox I, Oluwalana C, Lette K, Usuf E, Bottomley C, Howden BP, D'Alessandro U, Roca A.

Clin Infect Dis. 2018 Sep 28;67(8):1191-1197. doi: 10.1093/cid/ciy254. Erratum in: Clin Infect Dis. 2018 Sep 14;67(7):1150.


Adverse perinatal events, treatment gap, and positive family history linked to the high burden of active convulsive epilepsy in Uganda: A population-based study.

Kakooza-Mwesige A, Ndyomugyenyi D, Pariyo G, Peterson SS, Waiswa PM, Galiwango E, Chengo E, Odhiambo R, Ssewanyana D, Bottomley C, Ngugi AK, Newton CRJC; SEEDS Writing Group.

Epilepsia Open. 2017 Mar 13;2(2):188-198. doi: 10.1002/epi4.12048. eCollection 2017 Jun.


Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea.

Marks M, Mitjà O, Bottomley C, Kwakye C, Houinei W, Bauri M, Adwere P, Abdulai AA, Dua F, Boateng L, Wangi J, Ohene SA, Wangnapi R, Simpson SV, Miag H, Addo KK, Basing LA, Danavall D, Chi KH, Pillay A, Ballard R, Solomon AW, Chen CY, Bieb SV, Adu-Sarkodie Y, Mabey DCW, Asiedu K; study team.

Lancet Glob Health. 2018 Apr;6(4):e401-e410. doi: 10.1016/S2214-109X(18)30023-8. Epub 2018 Feb 16.


Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial.

Burr SE, Camara B, Oluwalana C, Bojang E, Bottomley C, Bojang A, Bailey RL, D'Alessandro U, Roca A.

BMC Infect Dis. 2017 Dec 28;17(1):799. doi: 10.1186/s12879-017-2909-4.


Ambulatory versus inpatient management of severe nausea and vomiting of pregnancy: a randomised control trial with patient preference arm.

Mitchell-Jones N, Farren JA, Tobias A, Bourne T, Bottomley C.

BMJ Open. 2017 Dec 5;7(12):e017566. doi: 10.1136/bmjopen-2017-017566.


Going paperless: a new era for patient-reported outcome measures in dermatology.

Bottomley CJ.

Br J Dermatol. 2017 Nov;177(5):1157-1158. doi: 10.1111/bjd.15731. No abstract available.


Exploring the role of competition induced by non-vaccine serotypes for herd protection following pneumococcal vaccination.

Masala GL, Lipsitch M, Bottomley C, Flasche S.

J R Soc Interface. 2017 Nov;14(136). pii: 20170620. doi: 10.1098/rsif.2017.0620.


Evaluating patient preference and satisfaction for human immunodeficiency virus therapy in France.

Brégigeon-Ronot S, Cheret A, Cabié A, Prazuck T, Volny-Anne A, Ali S, Bottomley C, Finkielsztejn L, Philippe C, Parienti JJ.

Patient Prefer Adherence. 2017 Jul 10;11:1159-1169. doi: 10.2147/PPA.S130276. eCollection 2017.


Maternal pneumococcal nasopharyngeal carriage and risk factors for neonatal carriage after the introduction of pneumococcal conjugate vaccines in The Gambia.

Usuf E, Bojang A, Camara B, Jagne I, Oluwalana C, Bottomley C, D'Alessandro U, Roca A.

Clin Microbiol Infect. 2018 Apr;24(4):389-395. doi: 10.1016/j.cmi.2017.07.018. Epub 2017 Jul 23.


Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies.

Mackenzie GA, Hill PC, Sahito SM, Jeffries DJ, Hossain I, Bottomley C, Uchendu U, Ameh D, Ndiaye M, Osuorah CD, Adeyemi O, Pathirana J, Olatunji Y, Abatan B, Ahameefula E, Muhammad BS, Fombah AE, Saha D, Mackenzie R, Plumb I, Akano A, Ebruke B, Ideh RC, Kuti B, Githua P, Olutunde E, Ofordile O, Green E, Usuf E, Badji H, Ikumapayi UNA, Manjang A, Salaudeen R, Nsekpong ED, Jarju S, Antonio M, Sambou S, Ceesay L, Lowe-Jallow Y, Sowe D, Jasseh M, Mulholland K, Knoll M, Levine OS, Howie SR, Adegbola RA, Greenwood BM, Corrah T.

Lancet Infect Dis. 2017 Sep;17(9):965-973. doi: 10.1016/S1473-3099(17)30321-3. Epub 2017 Jun 7. Erratum in: Lancet Infect Dis. 2018 Jul;18(7):715.


A discrete choice experiment to determine UK patient preference for attributes of disease modifying treatments in Multiple Sclerosis.

Bottomley C, Lloyd A, Bennett G, Adlard N.

J Med Econ. 2017 Aug;20(8):863-870. doi: 10.1080/13696998.2017.1336099. Epub 2017 Jun 14.


Response to the Letter to the Editor by Eberhard et al.

Bottomley C, Isham V, Vivas-Martínez S, Kuesel AC, Attah SK, Opoku NO, Lustigman S, Walker M, Basáñez MG.

Parasit Vectors. 2017 May 16;10(1):240. doi: 10.1186/s13071-017-2125-5.


Maternal colonization with Staphylococcus aureus and Group B streptococcus is associated with colonization in newborns.

Roca A, Bojang A, Camara B, Oluwalana C, Lette K, West P, D'Alessandro U, Bottomley C.

Clin Microbiol Infect. 2017 Dec;23(12):974-979. doi: 10.1016/j.cmi.2017.04.020. Epub 2017 May 3.


Modelling the elimination of river blindness using long-term epidemiological and programmatic data from Mali and Senegal.

Walker M, Stolk WA, Dixon MA, Bottomley C, Diawara L, Traoré MO, de Vlas SJ, Basáñez MG.

Epidemics. 2017 Mar;18:4-15. doi: 10.1016/j.epidem.2017.02.005.


The importance of physical function to people with osteoporosis.

Kerr C, Bottomley C, Shingler S, Giangregorio L, de Freitas HM, Patel C, Randall S, Gold DT.

Osteoporos Int. 2017 May;28(5):1597-1607. doi: 10.1007/s00198-017-3911-9. Epub 2017 Mar 6. Review.


The costs of providing antiretroviral therapy services to HIV-infected individuals presenting with advanced HIV disease at public health centres in Dar es Salaam, Tanzania: Findings from a randomised trial evaluating different health care strategies.

Kimaro GD, Mfinanga S, Simms V, Kivuyo S, Bottomley C, Hawkins N, Harrison TS, Jaffar S, Guinness L; REMSTART trial team.

PLoS One. 2017 Feb 24;12(2):e0171917. doi: 10.1371/journal.pone.0171917. eCollection 2017.


Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data.

Tusting LS, Bottomley C, Gibson H, Kleinschmidt I, Tatem AJ, Lindsay SW, Gething PW.

PLoS Med. 2017 Feb 21;14(2):e1002234. doi: 10.1371/journal.pmed.1002234. eCollection 2017 Feb.


Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial.

Oluwalana C, Camara B, Bottomley C, Goodier S, Bojang A, Kampmann B, Ceesay S, D'Alessandro U, Roca A.

Pediatrics. 2017 Feb;139(2). pii: e20162281. doi: 10.1542/peds.2016-2281.


Calorie Restriction Attenuates Terminal Differentiation of Immune Cells.

White MJ, Beaver CM, Goodier MR, Bottomley C, Nielsen CM, Wolf AF, Boldrin L, Whitmore C, Morgan J, Pearce DJ, Riley EM.

Front Immunol. 2017 Jan 12;7:667. doi: 10.3389/fimmu.2016.00667. eCollection 2016.


Can risk factors, clinical history and symptoms be used to predict risk of ectopic pregnancy in women attending an early pregnancy assessment unit?

Ayim F, Tapp S, Guha S, Ameye L, Al-Memar M, Sayasneh A, Bottomley C, Gould D, Stalder C, Timmerman D, Bourne T.

Ultrasound Obstet Gynecol. 2016 Nov;48(5):656-662. doi: 10.1002/uog.16007.


Childhood pneumonia and crowding, bed-sharing and nutrition: a case-control study from The Gambia.

Howie SR, Schellenberg J, Chimah O, Ideh RC, Ebruke BE, Oluwalana C, Mackenzie G, Jallow M, Njie M, Donkor S, Dionisio KL, Goldberg G, Fornace K, Bottomley C, Hill PC, Grant CC, Corrah T, Prentice AM, Ezzati M, Greenwood BM, Smith PG, Adegbola RA, Mulholland K.

Int J Tuberc Lung Dis. 2016 Oct;20(10):1405-1415.


Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma.

Marks M, Sokana O, Nachamkin E, Puiahi E, Kilua G, Pillay A, Bottomley C, Solomon AW, Mabey DC.

PLoS Negl Trop Dis. 2016 Aug 23;10(8):e0004927. doi: 10.1371/journal.pntd.0004927. eCollection 2016 Aug. Erratum in: PLoS Negl Trop Dis. 2018 Mar 7;12 (3):e0006308.


Why is malaria associated with poverty? Findings from a cohort study in rural Uganda.

Tusting LS, Rek J, Arinaitwe E, Staedke SG, Kamya MR, Cano J, Bottomley C, Johnston D, Dorsey G, Lindsay SW, Lines J.

Infect Dis Poverty. 2016 Aug 4;5(1):78. doi: 10.1186/s40249-016-0164-3.


Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta-analysis.

Mitchell-Jones N, Gallos I, Farren J, Tobias A, Bottomley C, Bourne T.

BJOG. 2017 Jan;124(1):20-30. doi: 10.1111/1471-0528.14180. Epub 2016 Jul 14. Review.

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