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Items: 1 to 50 of 116

1.

Idiopathic Normal-Pressure Hydrocephalus: Diagnostic Accuracy of Automated Sulcal Morphometry in Patients With Ventriculomegaly.

Kuchcinski G, Jacquiez C, Baroncini M, Machuron F, Béhal H, Dumont J, Lopes R, Delmaire C, Lebouvier T, Bottlaender M, Bordet R, Defebvre L, Pruvo JP, Leclerc X, Hodel J.

Neurosurgery. 2019 May 22. pii: nyz121. doi: 10.1093/neuros/nyz121. [Epub ahead of print]

PMID:
31115469
2.

11C-glyburide PET imaging unveils the negligible brain penetration of glyburide in humans.

Marie S, Comtat C, Caillé F, Becquemont L, Bottlaender M, Tournier N.

Neurology. 2019 Apr 23;92(17):813-814. doi: 10.1212/WNL.0000000000007378. No abstract available.

PMID:
31010910
3.

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies.

Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR Jr, Farlow MR, Salloway S, Snider BJ, Berman SB, Roberson ED, Brosch J, Jimenez-Velazques I, van Dyck CH, Galasko D, Yuan SH, Jayadev S, Honig LS, Gauthier S, Hsiung GR, Masellis M, Brooks WS, Fulham M, Clarnette R, Masters CL, Wallon D, Hannequin D, Dubois B, Pariente J, Sanchez-Valle R, Mummery C, Ringman JM, Bottlaender M, Klein G, Milosavljevic-Ristic S, McDade E, Xiong C, Morris JC, Bateman RJ, Benzinger TLS.

Alzheimers Dement (Amst). 2019 Feb 22;11:180-190. doi: 10.1016/j.dadm.2018.12.008. eCollection 2019 Dec.

4.

A Resting-State Functional MR Imaging and Spectroscopy Study of the Dorsal Hippocampus in the Chronic Unpredictable Stress Rat Model.

Magalhães R, Novais A, Barrière DA, Marques P, Marques F, Sousa JC, Cerqueira JJ, Cachia A, Jay TM, Bottlaender M, Sousa N, Mériaux S, Boumezbeur F.

J Neurosci. 2019 May 8;39(19):3640-3650. doi: 10.1523/JNEUROSCI.2192-18.2019. Epub 2019 Feb 25.

PMID:
30804096
5.

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau-Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Nora K, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M, Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R.

Ann Neurol. 2018 Nov;84(5):729-740. doi: 10.1002/ana.25333.

6.

Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease.

Hamelin L, Lagarde J, Dorothée G, Potier MC, Corlier F, Kuhnast B, Caillé F, Dubois B, Fillon L, Chupin M, Bottlaender M, Sarazin M.

Brain. 2018 Jun 1;141(6):1855-1870. doi: 10.1093/brain/awy079.

PMID:
29608645
7.

Neutrophil hyperactivation correlates with Alzheimer's disease progression.

Dong Y, Lagarde J, Xicota L, Corne H, Chantran Y, Chaigneau T, Crestani B, Bottlaender M, Potier MC, Aucouturier P, Dorothée G, Sarazin M, Elbim C.

Ann Neurol. 2018 Feb;83(2):387-405. doi: 10.1002/ana.25159.

PMID:
29369398
8.

The dynamics of stress: a longitudinal MRI study of rat brain structure and connectome.

Magalhães R, Barrière DA, Novais A, Marques F, Marques P, Cerqueira J, Sousa JC, Cachia A, Boumezbeur F, Bottlaender M, Jay TM, Mériaux S, Sousa N.

Mol Psychiatry. 2018 Oct;23(10):1998-2006. doi: 10.1038/mp.2017.244. Epub 2017 Dec 5.

PMID:
29203852
9.

Generalization of endothelial modelling of TSPO PET imaging: Considerations on tracer affinities.

Rizzo G, Veronese M, Tonietto M, Bodini B, Stankoff B, Wimberley C, Lavisse S, Bottlaender M, Bloomfield PS, Howes O, Zanotti-Fregonara P, Turkheimer FE, Bertoldo A.

J Cereb Blood Flow Metab. 2019 May;39(5):874-885. doi: 10.1177/0271678X17742004. Epub 2017 Nov 14.

PMID:
29135382
10.

Impact of Endothelial 18-kDa Translocator Protein on the Quantification of 18F-DPA-714.

Wimberley C, Lavisse S, Brulon V, Peyronneau MA, Leroy C, Bodini B, Remy P, Stankoff B, Buvat I, Bottlaender M.

J Nucl Med. 2018 Feb;59(2):307-314. doi: 10.2967/jnumed.117.195396. Epub 2017 Aug 3.

11.

In vivo PET imaging of neuroinflammation in Alzheimer's disease.

Lagarde J, Sarazin M, Bottlaender M.

J Neural Transm (Vienna). 2018 May;125(5):847-867. doi: 10.1007/s00702-017-1731-x. Epub 2017 May 17. Review.

PMID:
28516240
12.

Validation of an automatic reference region extraction for the quantification of [18F]DPA-714 in dynamic brain PET studies.

García-Lorenzo D, Lavisse S, Leroy C, Wimberley C, Bodini B, Remy P, Veronese M, Turkheimer F, Stankoff B, Bottlaender M.

J Cereb Blood Flow Metab. 2018 Feb;38(2):333-346. doi: 10.1177/0271678X17692599. Epub 2017 Feb 9.

13.

White matter changes in microstructure associated with a maladaptive response to stress in rats.

Magalhães R, Bourgin J, Boumezbeur F, Marques P, Bottlaender M, Poupon C, Djemaï B, Duchesnay E, Mériaux S, Sousa N, Jay TM, Cachia A.

Transl Psychiatry. 2017 Jan 24;7(1):e1009. doi: 10.1038/tp.2016.283.

14.

Acute Morphine Exposure Increases the Brain Distribution of [18F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates.

Auvity S, Saba W, Goutal S, Leroy C, Buvat I, Cayla J, Caillé F, Bottlaender M, Cisternino S, Tournier N.

Int J Neuropsychopharmacol. 2017 Jan 1;20(1):67-71. doi: 10.1093/ijnp/pyw077.

15.

Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage.

Bertoux M, Sarazin M, Pasquier F, Bottlaender M, de Souza LC, Mioshi E, Hornberger M, Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL.

Neurology. 2016 Oct 4;87(14):1523. No abstract available.

16.

Cholinergic Changes in Aging and Alzheimer Disease: An [18F]-F-A-85380 Exploratory PET Study.

Lagarde J, Sarazin M, Chauviré V, Stankoff B, Kas A, Lacomblez L, Peyronneau MA, Bottlaender M.

Alzheimer Dis Assoc Disord. 2017 Jan-Mar;31(1):8-12. doi: 10.1097/WAD.0000000000000163.

PMID:
27680780
17.

So Close Yet So Far: Executive Contribution to Memory Processing in Behavioral Variant Frontotemporal Dementia.

Bertoux M, Ramanan S, Slachevsky A, Wong S, Henriquez F, Musa G, Delgado C, Flanagan E, Bottlaender M, Sarazin M, Hornberger M, Dubois B.

J Alzheimers Dis. 2016 Oct 4;54(3):1005-1014.

PMID:
27567869
18.

Distinct tau PET imaging patterns in typical and atypical Alzheimer's disease.

Sarazin M, Lagarde J, Bottlaender M.

Brain. 2016 May;139(Pt 5):1321-4. doi: 10.1093/brain/aww041. No abstract available.

PMID:
27189580
19.

CATI: A Large Distributed Infrastructure for the Neuroimaging of Cohorts.

Operto G, Chupin M, Batrancourt B, Habert MO, Colliot O, Benali H, Poupon C, Champseix C, Delmaire C, Marie S, Rivière D, Pélégrini-Issac M, Perlbarg V, Trebossen R, Bottlaender M, Frouin V, Grigis A, Orfanos DP, Dary H, Fillon L, Azouani C, Bouyahia A, Fischer C, Edward L, Bouin M, Thoprakarn U, Li J, Makkaoui L, Poret S, Dufouil C, Bouteloup V, Chételat G, Dubois B, Lehéricy S, Mangin JF, Cointepas Y; CATI Consortium.

Neuroinformatics. 2016 Jul;14(3):253-64. doi: 10.1007/s12021-016-9295-8. Review.

PMID:
27066973
20.

Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging.

Hamelin L, Lagarde J, Dorothée G, Leroy C, Labit M, Comley RA, de Souza LC, Corne H, Dauphinot L, Bertoux M, Dubois B, Gervais P, Colliot O, Potier MC, Bottlaender M, Sarazin M; Clinical IMABio3 team.

Brain. 2016 Apr;139(Pt 4):1252-64. doi: 10.1093/brain/aww017. Epub 2016 Mar 15.

PMID:
26984188
21.

Dynamic Imaging of Individual Remyelination Profiles in Multiple Sclerosis.

Bodini B, Veronese M, García-Lorenzo D, Battaglini M, Poirion E, Chardain A, Freeman L, Louapre C, Tchikviladze M, Papeix C, Dollé F, Zalc B, Lubetzki C, Bottlaender M, Turkheimer F, Stankoff B.

Ann Neurol. 2016 May;79(5):726-738. doi: 10.1002/ana.24620.

22.

The neuronal component of gray matter damage in multiple sclerosis: A [(11) C]flumazenil positron emission tomography study.

Freeman L, Garcia-Lorenzo D, Bottin L, Leroy C, Louapre C, Bodini B, Papeix C, Assouad R, Granger B, Tourbah A, Dollé F, Lubetzki C, Bottlaender M, Stankoff B.

Ann Neurol. 2015 Oct;78(4):554-67. doi: 10.1002/ana.24468. Epub 2015 Aug 21.

PMID:
26292991
23.

Sulcal morphology as a new imaging marker for the diagnosis of early onset Alzheimer's disease.

Hamelin L, Bertoux M, Bottlaender M, Corne H, Lagarde J, Hahn V, Mangin JF, Dubois B, Chupin M, de Souza LC, Colliot O, Sarazin M.

Neurobiol Aging. 2015 Nov;36(11):2932-2939. doi: 10.1016/j.neurobiolaging.2015.04.019. Epub 2015 Jul 15.

PMID:
26256787
24.

Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer's disease patients.

Corlier F, Rivals I, Lagarde J, Hamelin L, Corne H, Dauphinot L, Ando K, Cossec JC, Fontaine G, Dorothée G, Malaplate-Armand C, Olivier JL, Dubois B, Bottlaender M, Duyckaerts C, Sarazin M, Potier MC; Clinical ImaBio3 Team.

Transl Psychiatry. 2015 Jul 7;5:e595. doi: 10.1038/tp.2015.87.

25.

Quantification of [(11)C]PIB PET for imaging myelin in the human brain: a test-retest reproducibility study in high-resolution research tomography.

Veronese M, Bodini B, García-Lorenzo D, Battaglini M, Bongarzone S, Comtat C, Bottlaender M, Stankoff B, Turkheimer FE.

J Cereb Blood Flow Metab. 2015 Nov;35(11):1771-82. doi: 10.1038/jcbfm.2015.120. Epub 2015 Jun 10.

26.

Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers.

Lavisse S, García-Lorenzo D, Peyronneau MA, Bodini B, Thiriez C, Kuhnast B, Comtat C, Remy P, Stankoff B, Bottlaender M.

J Nucl Med. 2015 Jul;56(7):1048-54. doi: 10.2967/jnumed.115.156083. Epub 2015 May 29.

27.

Hyper-responsivity to stress in rats is associated with a large increase in amygdala volume. A 7T MRI study.

Bourgin J, Cachia A, Boumezbeur F, Djemaï B, Bottlaender M, Duchesnay E, Mériaux S, Jay TM.

Eur Neuropsychopharmacol. 2015 Jun;25(6):828-35. doi: 10.1016/j.euroneuro.2015.02.010. Epub 2015 Mar 11.

PMID:
25823695
28.

Influence of P-Glycoprotein Inhibition or Deficiency at the Blood-Brain Barrier on (18)F-2-Fluoro-2-Deoxy-D-glucose ( (18)F-FDG) Brain Kinetics.

Tournier N, Saba W, Goutal S, Gervais P, Valette H, Scherrmann JM, Bottlaender M, Cisternino S.

AAPS J. 2015 May;17(3):652-9. doi: 10.1208/s12248-015-9739-3. Epub 2015 Feb 26.

29.

FID navigator-based MR thermometry method to monitor small temperature changes in the brain of ventilated animals.

Boulant N, Bottlaender M, Uhrig L, Giacomini E, Luong M, Amadon A, Massire A, Larrat B, Vignaud A.

NMR Biomed. 2015 Jan;28(1):101-7. doi: 10.1002/nbm.3232. Epub 2014 Nov 11.

PMID:
25388870
30.

[11C]befloxatone distribution is well correlated to monoamine oxidase A protein levels in the human brain.

Zanotti-Fregonara P, Bottlaender M.

J Cereb Blood Flow Metab. 2014 Dec;34(12):1951-2. doi: 10.1038/jcbfm.2014.157. Epub 2014 Sep 17.

31.

Imaging of monoamine oxidase-A in the human brain with [11C]befloxatone: quantification strategies and correlation with mRNA transcription maps.

Zanotti-Fregonara P, Leroy C, Rizzo G, Roumenov D, Trichard C, Martinot JL, Bottlaender M.

Nucl Med Commun. 2014 Dec;35(12):1254-61. doi: 10.1097/MNM.0000000000000196.

PMID:
25185897
32.

Plasma DYRK1A as a novel risk factor for Alzheimer's disease.

Janel N, Sarazin M, Corlier F, Corne H, de Souza LC, Hamelin L, Aka A, Lagarde J, Blehaut H, Hindié V, Rain JC, Arbones ML, Dubois B, Potier MC, Bottlaender M, Delabar JM.

Transl Psychiatry. 2014 Aug 12;4:e425. doi: 10.1038/tp.2014.61.

33.

Kinetic analysis of [11C]befloxatone in the human brain, a selective radioligand to image monoamine oxidase A.

Zanotti-Fregonara P, Leroy C, Roumenov D, Trichard C, Martinot JL, Bottlaender M.

EJNMMI Res. 2013 Nov 25;3(1):78. doi: 10.1186/2191-219X-3-78.

34.

Two distinct amnesic profiles in behavioral variant frontotemporal dementia.

Bertoux M, de Souza LC, Corlier F, Lamari F, Bottlaender M, Dubois B, Sarazin M.

Biol Psychiatry. 2014 Apr 1;75(7):582-8. doi: 10.1016/j.biopsych.2013.08.017. Epub 2013 Oct 3.

PMID:
24090793
35.

Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide.

Tournier N, Saba W, Cisternino S, Peyronneau MA, Damont A, Goutal S, Dubois A, Dollé F, Scherrmann JM, Valette H, Kuhnast B, Bottlaender M.

AAPS J. 2013 Oct;15(4):1082-90. doi: 10.1208/s12248-013-9514-2. Epub 2013 Aug 2.

36.

[(18)F]Fallypride: metabolism studies and quantification of the radiotracer and its radiometabolites in plasma using a simple and rapid solid-phase extraction method.

Peyronneau MA, Saba W, Goutal S, Kuhnast B, Dollé F, Bottlaender M, Valette H.

Nucl Med Biol. 2013 Oct;40(7):887-95. doi: 10.1016/j.nucmedbio.2013.06.003. Epub 2013 Jul 25.

PMID:
23891202
37.

High density of nicotinic receptors in the cingulo-insular network.

Picard F, Sadaghiani S, Leroy C, Courvoisier DS, Maroy R, Bottlaender M.

Neuroimage. 2013 Oct 1;79:42-51. doi: 10.1016/j.neuroimage.2013.04.074. Epub 2013 Apr 28.

PMID:
23631995
38.

Is hippocampal volume a good marker to differentiate Alzheimer's disease from frontotemporal dementia?

de Souza LC, Chupin M, Bertoux M, Lehéricy S, Dubois B, Lamari F, Le Ber I, Bottlaender M, Colliot O, Sarazin M.

J Alzheimers Dis. 2013;36(1):57-66. doi: 10.3233/JAD-122293.

39.

Metabolism and quantification of [(18)F]DPA-714, a new TSPO positron emission tomography radioligand.

Peyronneau MA, Saba W, Goutal S, Damont A, Dollé F, Kassiou M, Bottlaender M, Valette H.

Drug Metab Dispos. 2013 Jan;41(1):122-31. doi: 10.1124/dmd.112.046342. Epub 2012 Oct 12.

PMID:
23065531
40.

Distinct patterns of antiamyloid-β antibodies in typical and atypical Alzheimer disease.

Dorothée G, Bottlaender M, Moukari E, de Souza LC, Maroy R, Corlier F, Colliot O, Chupin M, Lamari F, Lehéricy S, Dubois B, Sarazin M, Aucouturier P.

Arch Neurol. 2012 Sep;69(9):1181-5. doi: 10.1001/archneurol.2012.604.

PMID:
22710357
41.

Discrepancies in the P-glycoprotein-mediated transport of (18)F-MPPF: a pharmacokinetic study in mice and non-human primates.

Tournier N, Cisternino S, Peyronneau MA, Goutal S, Dolle F, Scherrmann JM, Bottlaender M, Saba W, Valette H.

Pharm Res. 2012 Sep;29(9):2468-76. doi: 10.1007/s11095-012-0776-7. Epub 2012 May 30.

PMID:
22644589
42.

Minimally invasive input function for 2-18F-fluoro-A-85380 brain PET studies.

Zanotti-Fregonara P, Maroy R, Peyronneau MA, Trebossen R, Bottlaender M.

Eur J Nucl Med Mol Imaging. 2012 Apr;39(4):651-9. doi: 10.1007/s00259-011-2004-9. Epub 2012 Jan 10.

PMID:
22231015
43.

Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling: part II: Metabolism studies.

Peyronneau MA, Saba W, Dollé F, Goutal S, Coulon C, Bottlaender M, Valette H.

Nucl Med Biol. 2012 Apr;39(3):347-59. doi: 10.1016/j.nucmedbio.2011.09.006. Epub 2011 Dec 11.

PMID:
22154687
44.

Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling Part I: PET studies.

Saba W, Peyronneau MA, Dollé F, Goutal S, Bottlaender M, Valette H.

Nucl Med Biol. 2012 Feb;39(2):227-33. doi: 10.1016/j.nucmedbio.2011.08.003. Epub 2011 Oct 26.

PMID:
22033025
45.

Similar amyloid-β burden in posterior cortical atrophy and Alzheimer's disease.

de Souza LC, Corlier F, Habert MO, Uspenskaya O, Maroy R, Lamari F, Chupin M, Lehéricy S, Colliot O, Hahn-Barma V, Samri D, Dubois B, Bottlaender M, Sarazin M.

Brain. 2011 Jul;134(Pt 7):2036-43. doi: 10.1093/brain/awr130.

PMID:
21705422
46.

Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-¹¹C]-2-(4'-methylaminophenyl)- 6-hydroxybenzothiazole.

Stankoff B, Freeman L, Aigrot MS, Chardain A, Dollé F, Williams A, Galanaud D, Armand L, Lehericy S, Lubetzki C, Zalc B, Bottlaender M.

Ann Neurol. 2011 Apr;69(4):673-80. doi: 10.1002/ana.22320. Epub 2011 Feb 18.

PMID:
21337603
47.

Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening.

Tournier N, Valette H, Peyronneau MA, Saba W, Goutal S, Kuhnast B, Dollé F, Scherrmann JM, Cisternino S, Bottlaender M.

J Nucl Med. 2011 Mar;52(3):415-23. doi: 10.2967/jnumed.110.079608. Epub 2011 Feb 14.

48.

Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.

Mabondzo A, Bottlaender M, Guyot AC, Tsaouin K, Deverre JR, Balimane PV.

Mol Pharm. 2010 Oct 4;7(5):1805-15. doi: 10.1021/mp1002366. Epub 2010 Sep 15.

PMID:
20795735
49.

[18F]ZW-104, a new radioligand for imaging alpha2-alpha3-alpha4/beta2 central nicotinic acetylcholine receptors: Evaluation in mutant mice.

Saba W, Valette H, Granon S, Xiao Y, Kellar KJ, Dollé F, Bottlaender M.

Synapse. 2010 Jul;64(7):570-2. doi: 10.1002/syn.20776. No abstract available.

PMID:
20222155
50.

In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [(11)C]befloxatone and the multi-injection approach.

Bottlaender M, Valette H, Delforge J, Saba W, Guenther I, Curet O, George P, Dollé F, Grégoire MC.

J Cereb Blood Flow Metab. 2010 Apr;30(4):792-800. doi: 10.1038/jcbfm.2009.242. Epub 2009 Nov 18.

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