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Items: 1 to 50 of 118

1.

Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics.

Adami R, Pagano J, Colombo M, Platonova N, Recchia D, Chiaramonte R, Bottinelli R, Canepari M, Bottai D.

Front Neurosci. 2018 May 23;12:336. doi: 10.3389/fnins.2018.00336. eCollection 2018.

2.

High mobility group box 1 orchestrates tissue regeneration via CXCR4.

Tirone M, Tran NL, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, Raucci A, Di Maggio S, Santiago C, Mellado M, Saclier M, François S, Careccia G, He M, De Marchis F, Conti V, Ben Larbi S, Cuvellier S, Casalgrandi M, Preti A, Chazaud B, Al-Abed Y, Messina G, Sitia G, Brunelli S, Bianchi ME, Vénéreau E.

J Exp Med. 2018 Jan 2;215(1):303-318. doi: 10.1084/jem.20160217. Epub 2017 Dec 4.

3.

Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill.

van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1544-1558. doi: 10.1164/rccm.201703-0501OC.

PMID:
28787181
4.

Exercise training in Tgαq*44 mice during the progression of chronic heart failure: cardiac vs. peripheral (soleus muscle) impairments to oxidative metabolism.

Grassi B, Majerczak J, Bardi E, Buso A, Comelli M, Chlopicki S, Guzik M, Mavelli I, Nieckarz Z, Salvadego D, Tyrankiewicz U, Skórka T, Bottinelli R, Zoladz JA, Pellegrino MA.

J Appl Physiol (1985). 2017 Aug 1;123(2):326-336. doi: 10.1152/japplphysiol.00342.2017. Epub 2017 May 18.

PMID:
28522765
5.

Structure and function of human muscle fibres and muscle proteome in physically active older men.

Brocca L, McPhee JS, Longa E, Canepari M, Seynnes O, De Vito G, Pellegrino MA, Narici M, Bottinelli R.

J Physiol. 2017 Jul 15;595(14):4823-4844. doi: 10.1113/JP274148. Epub 2017 Jun 5.

6.

Myosin content of single muscle fibers following short-term disuse and active recovery in young and old healthy men.

Hvid LG, Brocca L, Ørtenblad N, Suetta C, Aagaard P, Kjaer M, Bottinelli R, Pellegrino MA.

Exp Gerontol. 2017 Jan;87(Pt A):100-107. doi: 10.1016/j.exger.2016.10.009. Epub 2016 Oct 26.

PMID:
27794458
7.

FoxO-dependent atrogenes vary among catabolic conditions and play a key role in muscle atrophy induced by hindlimb suspension.

Brocca L, Toniolo L, Reggiani C, Bottinelli R, Sandri M, Pellegrino MA.

J Physiol. 2017 Feb 15;595(4):1143-1158. doi: 10.1113/JP273097. Epub 2016 Dec 12.

8.

Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery.

Brocca L, Longa E, Cannavino J, Seynnes O, de Vito G, McPhee J, Narici M, Pellegrino MA, Bottinelli R.

J Physiol. 2015 Dec 15;593(24):5361-85. doi: 10.1113/JP271188.

9.

In vivo generation of a mature and functional artificial skeletal muscle.

Fuoco C, Rizzi R, Biondo A, Longa E, Mascaro A, Shapira-Schweitzer K, Kossovar O, Benedetti S, Salvatori ML, Santoleri S, Testa S, Bernardini S, Bottinelli R, Bearzi C, Cannata SM, Seliktar D, Cossu G, Gargioli C.

EMBO Mol Med. 2015 Apr;7(4):411-22. doi: 10.15252/emmm.201404062.

10.

Quantitative and qualitative adaptations of muscle fibers to glucocorticoids.

Minetto MA, Qaisar R, Agoni V, Motta G, Longa E, Miotti D, Pellegrino MA, Bottinelli R.

Muscle Nerve. 2015 Oct;52(4):631-9. doi: 10.1002/mus.24572. Epub 2015 Jun 30.

PMID:
25594832
11.

The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading.

Cannavino J, Brocca L, Sandri M, Grassi B, Bottinelli R, Pellegrino MA.

J Physiol. 2015 Apr 15;593(8):1981-95. doi: 10.1113/jphysiol.2014.286740. Epub 2015 Feb 4.

12.

Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging.

Carnio S, LoVerso F, Baraibar MA, Longa E, Khan MM, Maffei M, Reischl M, Canepari M, Loefler S, Kern H, Blaauw B, Friguet B, Bottinelli R, Rudolf R, Sandri M.

Cell Rep. 2014 Sep 11;8(5):1509-21. doi: 10.1016/j.celrep.2014.07.061. Epub 2014 Aug 28.

13.

PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice.

Cannavino J, Brocca L, Sandri M, Bottinelli R, Pellegrino MA.

J Physiol. 2014 Oct 15;592(20):4575-89. doi: 10.1113/jphysiol.2014.275545. Epub 2014 Aug 15.

14.

Molecular mechanism regulating myosin and cardiac functions by ELC.

Lossie J, Köhncke C, Mahmoodzadeh S, Steffen W, Canepari M, Maffei M, Taube M, Larchevêque O, Baumert P, Haase H, Bottinelli R, Regitz-Zagrosek V, Morano I.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):464-9. doi: 10.1016/j.bbrc.2014.05.142. Epub 2014 Jun 6.

PMID:
24911555
15.

Actin sliding velocity on pure myosin isoforms from hindlimb unloaded mice.

Maffei M, Longa E, Qaisar R, Agoni V, Desaphy JF, Camerino DC, Bottinelli R, Canepari M.

Acta Physiol (Oxf). 2014 Dec;212(4):316-29. doi: 10.1111/apha.12320. Epub 2014 Jun 30.

PMID:
24888432
16.

Physiological and functional evaluation of healthy young and older men and women: design of the European MyoAge study.

McPhee JS, Hogrel JY, Maier AB, Seppet E, Seynnes OR, Sipilä S, Bottinelli R, Barnouin Y, Bijlsma AY, Gapeyeva H, Maden-Wilkinson TM, Meskers CG, Pääsuke M, Sillanpää E, Stenroth L, Butler-Browne G, Narici MV, Jones DA.

Biogerontology. 2013 Jun;14(3):325-37. doi: 10.1007/s10522-013-9434-7. Epub 2013 May 31.

PMID:
23722256
17.

Skeletal muscle adaptations to physical inactivity and subsequent retraining in young men.

Campbell EL, Seynnes OR, Bottinelli R, McPhee JS, Atherton PJ, Jones DA, Butler-Browne G, Narici MV.

Biogerontology. 2013 Jun;14(3):247-59. doi: 10.1007/s10522-013-9427-6. Epub 2013 May 12.

PMID:
23666342
18.

Corrigendum: Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs.

Sampaolesi M, Blot S, D'Antona G, Granger N, Tonlorenzi R, Innocenzi A, Mognol P, Thibaud JL, Galvez BG, Barthélémy I, Perani L, Mantero S, Guttinger M, Pansarasa O, Rinaldi C, De Angelis MG, Torrente Y, Bordignon C, Bottinelli R, Cossu G.

Nature. 2013 Feb 20;494(7438):506. doi: 10.1038/nature11976. Epub 2013 Feb 20. No abstract available.

PMID:
23426261
19.

Variability in muscle adaptation to electrical stimulation.

Minetto MA, Botter A, Bottinelli O, Miotti D, Bottinelli R, D'Antona G.

Int J Sports Med. 2013 Jun;34(6):544-53. doi: 10.1055/s-0032-1321799. Epub 2013 Jan 7.

PMID:
23296400
20.

Nitric oxide prevents atorvastatin-induced skeletal muscle dysfunction and alterations in mice.

D'Antona G, Mascaro A, Monopoli A, Miglietta D, Ongini E, Bottinelli R.

Muscle Nerve. 2013 Jan;47(1):72-80. doi: 10.1002/mus.23465. Epub 2012 Oct 5.

PMID:
23042511
21.

Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke.

Capitanio M, Canepari M, Maffei M, Beneventi D, Monico C, Vanzi F, Bottinelli R, Pavone FS.

Nat Methods. 2012 Oct;9(10):1013-9. doi: 10.1038/nmeth.2152. Epub 2012 Sep 2.

PMID:
22941363
22.

Lack of functional effects of neuromuscular electrical stimulation on skeletal muscle oxidative metabolism in healthy humans.

Porcelli S, Marzorati M, Pugliese L, Adamo S, Gondin J, Bottinelli R, Grassi B.

J Appl Physiol (1985). 2012 Oct;113(7):1101-9. doi: 10.1152/japplphysiol.01627.2011. Epub 2012 Aug 16.

23.

The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms.

Brocca L, Cannavino J, Coletto L, Biolo G, Sandri M, Bottinelli R, Pellegrino MA.

J Physiol. 2012 Oct 15;590(20):5211-30. doi: 10.1113/jphysiol.2012.240267. Epub 2012 Jul 30.

24.

Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.

Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G.

Sci Transl Med. 2012 Jun 27;4(140):140ra89. doi: 10.1126/scitranslmed.3003541.

25.

Actomyosin kinetics of pure fast and slow rat myosin isoforms studied by in vitro motility assay approach.

Canepari M, Maffei M, Longa E, Geeves M, Bottinelli R.

Exp Physiol. 2012 Jul;97(7):873-81. doi: 10.1113/expphysiol.2012.064576. Epub 2012 Mar 30.

26.

Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model.

Farini A, Sitzia C, Navarro C, D'Antona G, Belicchi M, Parolini D, Del Fraro G, Razini P, Bottinelli R, Meregalli M, Torrente Y.

Exp Cell Res. 2012 Jun 10;318(10):1160-74. doi: 10.1016/j.yexcr.2012.03.010. Epub 2012 Mar 23.

PMID:
22465227
27.

Electrical stimulation for neuromuscular testing and training: state-of-the art and unresolved issues.

Maffiuletti NA, Minetto MA, Farina D, Bottinelli R.

Eur J Appl Physiol. 2011 Oct;111(10):2391-7. doi: 10.1007/s00421-011-2133-7. Epub 2011 Aug 25. No abstract available.

PMID:
21866361
28.

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.

Tedesco FS, Hoshiya H, D'Antona G, Gerli MF, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M, Cossu G.

Sci Transl Med. 2011 Aug 17;3(96):96ra78. doi: 10.1126/scitranslmed.3002342.

29.

Reactive oxygen and nitrogen species in skeletal muscle: acute and long-term effects.

Bottinelli R, Westerblad H.

J Physiol. 2011 May 1;589(Pt 9):2117-8. doi: 10.1113/jphysiol.2011.209437. No abstract available.

30.

Redox homeostasis, oxidative stress and disuse muscle atrophy.

Pellegrino MA, Desaphy JF, Brocca L, Pierno S, Camerino DC, Bottinelli R.

J Physiol. 2011 May 1;589(Pt 9):2147-60. doi: 10.1113/jphysiol.2010.203232. Epub 2011 Feb 14. Review.

31.

Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle.

Camerino GM, Pellegrino MA, Brocca L, Digennaro C, Camerino DC, Pierno S, Bottinelli R.

Biochem Pharmacol. 2011 Apr 15;81(8):1054-64. doi: 10.1016/j.bcp.2011.01.022. Epub 2011 Feb 15.

PMID:
21300028
32.

Neuromuscular electrical stimulation training induces atypical adaptations of the human skeletal muscle phenotype: a functional and proteomic analysis.

Gondin J, Brocca L, Bellinzona E, D'Antona G, Maffiuletti NA, Miotti D, Pellegrino MA, Bottinelli R.

J Appl Physiol (1985). 2011 Feb;110(2):433-50. doi: 10.1152/japplphysiol.00914.2010. Epub 2010 Dec 2.

33.

Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice.

D'Antona G, Ragni M, Cardile A, Tedesco L, Dossena M, Bruttini F, Caliaro F, Corsetti G, Bottinelli R, Carruba MO, Valerio A, Nisoli E.

Cell Metab. 2010 Oct 6;12(4):362-372. doi: 10.1016/j.cmet.2010.08.016.

34.

Essential amino acids improve insulin activation of AKT/MTOR signaling in soleus muscle of aged rats.

Flati V, Caliaro F, Speca S, Corsetti G, Cardile A, Nisoli E, Bottinelli R, D' Antona G.

Int J Immunopathol Pharmacol. 2010 Jan-Mar;23(1):81-9.

PMID:
20377997
35.

Skeletal muscle fibre diversity and the underlying mechanisms.

Canepari M, Pellegrino MA, D'Antona G, Bottinelli R.

Acta Physiol (Oxf). 2010 Aug;199(4):465-76. doi: 10.1111/j.1748-1716.2010.02118.x. Epub 2010 Mar 24. Review.

PMID:
20345415
36.

Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles.

Desaphy JF, Pierno S, Liantonio A, Giannuzzi V, Digennaro C, Dinardo MM, Camerino GM, Ricciuti P, Brocca L, Pellegrino MA, Bottinelli R, Camerino DC.

Pharmacol Res. 2010 Jun;61(6):553-63. doi: 10.1016/j.phrs.2010.01.012. Epub 2010 Jan 29.

PMID:
20116431
37.

The KATP channel is a molecular sensor of atrophy in skeletal muscle.

Tricarico D, Mele A, Camerino GM, Bottinelli R, Brocca L, Frigeri A, Svelto M, George AL Jr, Camerino DC.

J Physiol. 2010 Mar 1;588(Pt 5):773-84. doi: 10.1113/jphysiol.2009.185835. Epub 2010 Jan 11.

38.

Myosin and actin content of human skeletal muscle fibers following 35 days bed rest.

Borina E, Pellegrino MA, D'Antona G, Bottinelli R.

Scand J Med Sci Sports. 2010 Feb;20(1):65-73. doi: 10.1111/j.1600-0838.2009.01029.x.

PMID:
19883388
39.

Single muscle fiber properties in aging and disuse.

Canepari M, Pellegrino MA, D'Antona G, Bottinelli R.

Scand J Med Sci Sports. 2010 Feb;20(1):10-9. doi: 10.1111/j.1600-0838.2009.00965.x. Epub 2009 Oct 14. Review.

PMID:
19843264
40.

Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb-unloaded mice.

Brocca L, Pellegrino MA, Desaphy JF, Pierno S, Camerino DC, Bottinelli R.

Exp Physiol. 2010 Feb;95(2):331-50. doi: 10.1113/expphysiol.2009.050245. Epub 2009 Oct 9.

41.

Actin sliding velocity on pure myosin isoforms from dystrophic mouse muscles.

Canepari M, Rossi R, Pansarasa O, Maffei M, Bottinelli R.

Muscle Nerve. 2009 Aug;40(2):249-56. doi: 10.1002/mus.21302.

PMID:
19609904
42.

Focal adhesion kinase is a load-dependent governor of the slow contractile and oxidative muscle phenotype.

Durieux AC, D'Antona G, Desplanches D, Freyssenet D, Klossner S, Bottinelli R, Flück M.

J Physiol. 2009 Jul 15;587(Pt 14):3703-17. doi: 10.1113/jphysiol.2009.171355. Epub 2009 May 26.

43.

Resistance training of long duration modulates force and unloaded shortening velocity of single muscle fibres of young women.

Pansarasa O, Rinaldi C, Parente V, Miotti D, Capodaglio P, Bottinelli R.

J Electromyogr Kinesiol. 2009 Oct;19(5):e290-300. doi: 10.1016/j.jelekin.2008.07.007. Epub 2008 Sep 17.

PMID:
18801662
44.

Long-term resistance training improves force and unloaded shortening velocity of single muscle fibres of elderly women.

Parente V, D'Antona G, Adami R, Miotti D, Capodaglio P, De Vito G, Bottinelli R.

Eur J Appl Physiol. 2008 Nov;104(5):885-93. doi: 10.1007/s00421-008-0845-0. Epub 2008 Aug 2.

PMID:
18677504
45.

Restoration of human dystrophin following transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice.

Benchaouir R, Meregalli M, Farini A, D'Antona G, Belicchi M, Goyenvalle A, Battistelli M, Bresolin N, Bottinelli R, Garcia L, Torrente Y.

Cell Stem Cell. 2007 Dec 13;1(6):646-57. doi: 10.1016/j.stem.2007.09.016.

46.

[Restoration of human dystrophin following transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice].

Benchaouir R, Meregalli M, Farini A, D'Antona G, Belicchi M, Goyenvalle A, Battistelli M, Bresolin N, Bottinelli R, Garcia L, Torrente Y.

Med Sci (Paris). 2008 Jan;24(1):99-101. doi: 10.1051/medsci/200824199. French. No abstract available.

47.

Autologous transplantation of muscle-derived CD133+ stem cells in Duchenne muscle patients.

Torrente Y, Belicchi M, Marchesi C, D'Antona G, Cogiamanian F, Pisati F, Gavina M, Giordano R, Tonlorenzi R, Fagiolari G, Lamperti C, Porretti L, Lopa R, Sampaolesi M, Vicentini L, Grimoldi N, Tiberio F, Songa V, Baratta P, Prelle A, Forzenigo L, Guglieri M, Pansarasa O, Rinaldi C, Mouly V, Butler-Browne GS, Comi GP, Biondetti P, Moggio M, Gaini SM, Stocchetti N, Priori A, D'Angelo MG, Turconi A, Bottinelli R, Cossu G, Rebulla P, Bresolin N.

Cell Transplant. 2007;16(6):563-77.

PMID:
17912948
48.

Structural and functional alterations of muscle fibres in the novel mouse model of facioscapulohumeral muscular dystrophy.

D'Antona G, Brocca L, Pansarasa O, Rinaldi C, Tupler R, Bottinelli R.

J Physiol. 2007 Nov 1;584(Pt 3):997-1009. Epub 2007 Sep 13.

49.

T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.

Farini A, Meregalli M, Belicchi M, Battistelli M, Parolini D, D'Antona G, Gavina M, Ottoboni L, Constantin G, Bottinelli R, Torrente Y.

J Pathol. 2007 Oct;213(2):229-38.

PMID:
17668421
50.

Deterioration of contractile properties of muscle fibres in elderly subjects is modulated by the level of physical activity.

D'Antona G, Pellegrino MA, Carlizzi CN, Bottinelli R.

Eur J Appl Physiol. 2007 Jul;100(5):603-11. Epub 2007 Feb 2.

PMID:
17273882

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