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Items: 1 to 50 of 164

1.

Immunization with Pentraxin3 prevents transition from subclinical to clinical lupus nephritis in lupus-prone mice: Insights from renal ultrastructural findings.

Gatto M, Radu CM, Luisetto R, Ghirardello A, Bonsembiante F, Trez D, Valentino S, Bottazzi B, Simioni P, Cavicchioli L, Doria A.

J Autoimmun. 2020 Apr 4:102443. doi: 10.1016/j.jaut.2020.102443. [Epub ahead of print]

PMID:
32265078
2.

Editorial: Immunomodulation of Innate Immune Cells.

Almeida CR, Bottazzi B, De Nardo D, Lawlor KE.

Front Immunol. 2020 Feb 11;11:101. doi: 10.3389/fimmu.2020.00101. eCollection 2020. No abstract available.

3.

Correction: The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2.

Inforzato A, Baldock C, Jowitt TA, Holmes DF, Lindstedt R, Marcellini M, Rivieccio V, Briggs DC, Kadler KE, Verdoliva A, Bottazzi B, Mantovani A, Salvatori G, Day AJ.

J Biol Chem. 2020 Feb 7;295(6):1768. doi: 10.1074/jbc.AAC120.012568. No abstract available.

4.

The complement system in Aspergillus fumigatus infections and its crosstalk with pentraxins.

Parente R, Doni A, Bottazzi B, Garlanda C, Inforzato A.

FEBS Lett. 2020 Jan 28. doi: 10.1002/1873-3468.13744. [Epub ahead of print] Review.

PMID:
31994174
5.

Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium.

Weiner J, Lewis DJM, Maertzdorf J, Mollenkopf HJ, Bodinham C, Pizzoferro K, Linley C, Greenwood A, Mantovani A, Bottazzi B, Denoel P, Leroux-Roels G, Kester KE, Jonsdottir I, van den Berg R, Kaufmann SHE, Del Giudice G.

Sci Rep. 2019 Dec 30;9(1):20362. doi: 10.1038/s41598-019-56994-8.

6.

Editorial: The Role of Pentraxins: From Inflammation, Tissue Repair and Immunity to Biomarkers.

Bottazzi B, Garlanda C, Teixeira MM.

Front Immunol. 2019 Dec 3;10:2817. doi: 10.3389/fimmu.2019.02817. eCollection 2019. No abstract available.

7.

Determination of pentraxin 3 levels in cerebrospinal fluid during central nervous system infections.

Zatta M, Di Bella S, Bottazzi B, Rossi F, D'Agaro P, Segat L, Fabbiani M, Mantovani A, Luzzati R.

Eur J Clin Microbiol Infect Dis. 2020 Apr;39(4):665-670. doi: 10.1007/s10096-019-03767-w. Epub 2019 Dec 8.

PMID:
31813079
8.

The Long Pentraxin PTX3 in Bone Homeostasis and Pathology.

Parente R, Sobacchi C, Bottazzi B, Mantovani A, Grčevic D, Inforzato A.

Front Immunol. 2019 Nov 8;10:2628. doi: 10.3389/fimmu.2019.02628. eCollection 2019. Review.

9.

Imbalance between angiogenic and anti-angiogenic factors in sera from patients with large-vessel vasculitis.

Pulsatelli L, Boiardi L, Assirelli E, Pazzola G, Muratore F, Addimanda O, Dolzani P, Versari A, Casali M, Bottazzi B, Magnani L, Pignotti E, Pipitone N, Croci S, Mantovani A, Salvarani C, Meliconi R.

Clin Exp Rheumatol. 2019 Sep 17. [Epub ahead of print]

PMID:
31573481
10.

The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance.

Del Prete A, Sozio F, Schioppa T, Ponzetta A, Vermi W, Calza S, Bugatti M, Salvi V, Bernardini G, Benvenuti F, Vecchi A, Bottazzi B, Mantovani A, Sozzani S.

Cancer Immunol Res. 2019 Nov;7(11):1775-1788. doi: 10.1158/2326-6066.CIR-19-0168. Epub 2019 Sep 4.

PMID:
31484658
11.

Coronary Inflammation by Computed Tomography Pericoronary Fat Attenuation in MINOCA and Tako-Tsubo Syndrome.

Gaibazzi N, Martini C, Botti A, Pinazzi A, Bottazzi B, Palumbo AA.

J Am Heart Assoc. 2019 Sep 3;8(17):e013235. doi: 10.1161/JAHA.119.013235. Epub 2019 Aug 29.

12.

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.

Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, Doni A, Lonardi S, Astrid Boutet M, Nerviani A, Carriero R, Molgora M, Stravalaci M, Morone D, Shalova IN, Lee Y, Biswas SK, Mantovani G, Sironi M, Pitzalis C, Vermi W, Bottazzi B, Mantovani A, Locati M.

Nat Immunol. 2019 Aug;20(8):1012-1022. doi: 10.1038/s41590-019-0417-y. Epub 2019 Jul 1.

PMID:
31263276
13.

Pentraxin 3 in Cardiovascular Disease.

Ristagno G, Fumagalli F, Bottazzi B, Mantovani A, Olivari D, Novelli D, Latini R.

Front Immunol. 2019 Apr 17;10:823. doi: 10.3389/fimmu.2019.00823. eCollection 2019. Review.

14.

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis.

Porte R, Davoudian S, Asgari F, Parente R, Mantovani A, Garlanda C, Bottazzi B.

Front Immunol. 2019 Apr 12;10:794. doi: 10.3389/fimmu.2019.00794. eCollection 2019. Review.

15.

The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer.

Doni A, Stravalaci M, Inforzato A, Magrini E, Mantovani A, Garlanda C, Bottazzi B.

Front Immunol. 2019 Apr 4;10:712. doi: 10.3389/fimmu.2019.00712. eCollection 2019. Review.

16.

Interaction of C1q With Pentraxin 3 and IgM Revisited: Mutational Studies With Recombinant C1q Variants.

Bally I, Inforzato A, Dalonneau F, Stravalaci M, Bottazzi B, Gaboriaud C, Thielens NM.

Front Immunol. 2019 Mar 14;10:461. doi: 10.3389/fimmu.2019.00461. eCollection 2019.

17.

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.

Bonacina F, Moregola A, Porte R, Baragetti A, Bonavita E, Salatin A, Grigore L, Pellegatta F, Molgora M, Sironi M, Barbati E, Mantovani A, Bottazzi B, Catapano AL, Garlanda C, Norata GD.

Cardiovasc Res. 2019 Nov 1;115(13):1861-1872. doi: 10.1093/cvr/cvz068.

18.

Aging, inflammation and cancer.

Bottazzi B, Riboli E, Mantovani A.

Semin Immunol. 2018 Dec;40:74-82. doi: 10.1016/j.smim.2018.10.011. Epub 2018 Nov 6. Review.

PMID:
30409538
19.

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin.

Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F, Moretti M, Gotti C, Annis DS, Mosher DF, Garlanda C, Bottazzi B, Taraboletti G, Mantovani A, Matteoli M, Menna E.

EMBO J. 2019 Jan 3;38(1). pii: e99529. doi: 10.15252/embj.201899529. Epub 2018 Nov 5.

20.

Corrigendum to "Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation" [Biochim. Biophys. Acta, 1862 (2016) 1182-1190].

Bonacina F, Barbieri SS, Cutuli L, Amadi P, Don A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):262. doi: 10.1016/j.bbadis.2018.09.017. Epub 2018 Oct 16. No abstract available.

21.

The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair.

Grčević D, Sironi M, Valentino S, Deban L, Cvija H, Inforzato A, Kovačić N, Katavić V, Kelava T, Kalajzić I, Mantovani A, Bottazzi B.

Front Immunol. 2018 Mar 5;9:417. doi: 10.3389/fimmu.2018.00417. eCollection 2018.

22.

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer.

Garlanda C, Bottazzi B, Magrini E, Inforzato A, Mantovani A.

Physiol Rev. 2018 Apr 1;98(2):623-639. doi: 10.1152/physrev.00016.2017.

23.

Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination.

Haks MC, Bottazzi B, Cecchinato V, De Gregorio C, Del Giudice G, Kaufmann SHE, Lanzavecchia A, Lewis DJM, Maertzdorf J, Mantovani A, Sallusto F, Sironi M, Uguccioni M, Ottenhoff THM.

Front Immunol. 2017 Nov 15;8:1563. doi: 10.3389/fimmu.2017.01563. eCollection 2017. Review.

24.

Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers.

Pavanello S, Stendardo M, Mastrangelo G, Bonci M, Bottazzi B, Campisi M, Nardini M, Leone R, Mantovani A, Boschetto P.

Front Immunol. 2017 May 9;8:516. doi: 10.3389/fimmu.2017.00516. eCollection 2017.

25.

Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases.

Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, Bottazzi B, Lyberg T, Manzi S, Ahearn JM, Hollan I.

PLoS One. 2017 Mar 31;12(3):e0174577. doi: 10.1371/journal.pone.0174577. eCollection 2017.

26.

Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera.

Lussana F, Carobbio A, Salmoiraghi S, Guglielmelli P, Vannucchi AM, Bottazzi B, Leone R, Mantovani A, Barbui T, Rambaldi A.

J Hematol Oncol. 2017 Feb 22;10(1):54. doi: 10.1186/s13045-017-0425-z.

27.

Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

Deyab G, Hokstad I, Whist JE, Småstuen MC, Agewall S, Lyberg T, Bottazzi B, Meroni PL, Leone R, Hjeltnes G, Hollan I.

PLoS One. 2017 Feb 22;12(2):e0169830. doi: 10.1371/journal.pone.0169830. eCollection 2017.

28.

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation.

Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S, Cappuzzello C, Prunotto G, Pavan F, Pasqualini F, Sironi M, Cuccovillo I, Leone R, Salvatori G, Parma M, Terruzzi E, Pagni F, Locatelli F, Mantovani A, Fagioli F, Biondi A, Garlanda C, Valsecchi MG, Rovelli A, D'Amico G.

Oncotarget. 2016 Dec 13;7(50):82123-82138. doi: 10.18632/oncotarget.13488.

29.

Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial.

Caironi P, Masson S, Mauri T, Bottazzi B, Leone R, Magnoli M, Barlera S, Mamprin F, Fedele A, Mantovani A, Tognoni G, Pesenti A, Gattinoni L, Latini R; ALBIOS Biomarkers Study Investigators.

Eur J Clin Invest. 2017 Jan;47(1):73-83. doi: 10.1111/eci.12704. Epub 2016 Dec 14.

30.

Pentraxins in the activation and regulation of innate immunity.

Daigo K, Inforzato A, Barajon I, Garlanda C, Bottazzi B, Meri S, Mantovani A.

Immunol Rev. 2016 Nov;274(1):202-217. doi: 10.1111/imr.12476. Review.

31.

Endothelial cell-derived pentraxin 3 limits the vasoreparative therapeutic potential of circulating angiogenic cells.

O'Neill CL, Guduric-Fuchs J, Chambers SE, O'Doherty M, Bottazzi B, Stitt AW, Medina RJ.

Cardiovasc Res. 2016 Dec;112(3):677-688. Epub 2016 Sep 22.

32.

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation.

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta. 2016 Jun;1862(6):1182-90. doi: 10.1016/j.bbadis.2016.03.007. Epub 2016 Mar 11.

33.

Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q.

Moreau C, Bally I, Chouquet A, Bottazzi B, Ghebrehiwet B, Gaboriaud C, Thielens N.

Front Immunol. 2016 Mar 2;7:79. doi: 10.3389/fimmu.2016.00079. eCollection 2016.

34.

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling.

Bottazzi B, Inforzato A, Messa M, Barbagallo M, Magrini E, Garlanda C, Mantovani A.

J Hepatol. 2016 Jun;64(6):1416-27. doi: 10.1016/j.jhep.2016.02.029. Epub 2016 Feb 26. Review.

35.

Detection of Anti-Pentraxin-3 Autoantibodies in ANCA-Associated Vasculitis.

Simon A, Subra JF, Guilpain P, Jeannin P, Pignon P, Blanchard S, Garo E, Jaillon S, Chevailler A, Renier G, Puéchal X, Bottazzi B, Mantovani A, Delneste Y, Augusto JF.

PLoS One. 2016 Jan 21;11(1):e0147091. doi: 10.1371/journal.pone.0147091. eCollection 2016.

36.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A, Garlanda C, D'Amico G.

J Invest Dermatol. 2016 Jan;136(1):293-300. doi: 10.1038/JID.2015.346.

37.

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition.

Garlanda C, Jaillon S, Doni A, Bottazzi B, Mantovani A.

Curr Opin Immunol. 2016 Feb;38:39-44. doi: 10.1016/j.coi.2015.11.002. Epub 2015 Nov 30. Review.

38.

Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners.

Casimirri E, Stendardo M, Bonci M, Andreoli R, Bottazzi B, Leone R, Schito M, Vaccari A, Papi A, Contoli M, Corradi M, Boschetto P.

Biomarkers. 2016;21(2):115-22. doi: 10.3109/1354750X.2015.1118541. Epub 2015 Dec 9.

PMID:
26649641
39.

Pentraxin-3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease.

Ummenthum K, Peferoen LA, Finardi A, Baker D, Pryce G, Mantovani A, Bsibsi M, Bottazzi B, Peferoen-Baert R, van der Valk P, Garlanda C, Kipp M, Furlan R, van Noort JM, Amor S.

Eur J Immunol. 2016 Mar;46(3):701-11. doi: 10.1002/eji.201545950. Epub 2015 Dec 14.

40.

Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome.

Mullen L, Seavill M, Hammouz R, Bottazzi B, Chan P, Vaudry D, Ghezzi P.

Sci Rep. 2015 Sep 29;5:14630. doi: 10.1038/srep14630.

41.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A, Garlanda C, D'Amico G.

J Invest Dermatol. 2015 Sep 3. doi: 10.1038/jid.2015.346. [Epub ahead of print]

PMID:
26340034
42.

Elevations of inflammatory markers PTX3 and sST2 after resuscitation from cardiac arrest are associated with multiple organ dysfunction syndrome and early death.

Ristagno G, Varpula T, Masson S, Greco M, Bottazzi B, Milani V, Aleksova A, Sinagra G, Assandri R, Tiainen M, Vaahersalo J, Kurola J, Barlera S, Montanelli A, Latini R, Pettilä V, Bendel S, Skrifvars MB; FINNRESUSCI Study Group.

Clin Chem Lab Med. 2015 Oct;53(11):1847-57. doi: 10.1515/cclm-2014-1271.

PMID:
25993733
43.

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A.

J Exp Med. 2015 Jun 1;212(6):905-25. doi: 10.1084/jem.20141268. Epub 2015 May 11.

44.

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant.

Bottazzi B, Santini L, Savino S, Giuliani MM, Dueñas Díez AI, Mancuso G, Beninati C, Sironi M, Valentino S, Deban L, Garlanda C, Teti G, Pizza M, Rappuoli R, Mantovani A.

PLoS One. 2015 Mar 18;10(3):e0120807. doi: 10.1371/journal.pone.0120807. eCollection 2015.

45.

Systemic pentraxin-3 levels reflect vascular enhancement and progression in Takayasu arteritis.

Tombetti E, Di Chio MC, Sartorelli S, Papa M, Salerno A, Bottazzi B, Bozzolo EP, Greco M, Rovere-Querini P, Baldissera E, Del Maschio A, Mantovani A, De Cobelli F, Sabbadini MG, Manfredi AA.

Arthritis Res Ther. 2014 Nov 14;16(6):479. doi: 10.1186/s13075-014-0479-z.

46.

Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational study.

Mauri T, Coppadoro A, Bombino M, Bellani G, Zambelli V, Fornari C, Berra L, Bittner EA, Schmidt U, Sironi M, Bottazzi B, Brambilla P, Mantovani A, Pesenti A.

Crit Care. 2014 Oct 15;18(5):562. doi: 10.1186/s13054-014-0562-5.

47.

PTX3 binds MD-2 and promotes TRIF-dependent immune protection in aspergillosis.

Bozza S, Campo S, Arseni B, Inforzato A, Ragnar L, Bottazzi B, Mantovani A, Moretti S, Oikonomous V, De Santis R, Carvalho A, Salvatori G, Romani L.

J Immunol. 2014 Sep 1;193(5):2340-8. doi: 10.4049/jimmunol.1400814. Epub 2014 Jul 21.

48.

A new surface plasmon resonance-based immunoassay for rapid, reproducible and sensitive quantification of pentraxin-3 in human plasma.

Canovi M, Lucchetti J, Stravalaci M, Valentino S, Bottazzi B, Salmona M, Bastone A, Gobbi M.

Sensors (Basel). 2014 Jun 19;14(6):10864-75. doi: 10.3390/s140610864.

49.

The yin-yang of long pentraxin PTX3 in inflammation and immunity.

Daigo K, Mantovani A, Bottazzi B.

Immunol Lett. 2014 Sep;161(1):38-43. doi: 10.1016/j.imlet.2014.04.012. Epub 2014 May 1. Review.

50.

Multiplexed label-free optical biosensor for medical diagnostics.

Bottazzi B, Fornasari L, Frangolho A, Giudicatti S, Mantovani A, Marabelli F, Marchesini G, Pellacani P, Therisod R, Valsesia A.

J Biomed Opt. 2014 Jan;19(1):17006. doi: 10.1117/1.JBO.19.1.017006.

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