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Items: 1 to 50 of 78

1.

CpALS4770 and CpALS4780 contribution to the virulence of Candida parapsilosis.

Zoppo M, Di Luca M, Franco M, Rizzato C, Lupetti A, Stringaro A, De Bernardis F, Schaudinn C, Barrasa MI, Bottai D, Vyas VK, Tavanti A.

Microbiol Res. 2019 Oct 18;231:126351. doi: 10.1016/j.micres.2019.126351. [Epub ahead of print]

PMID:
31707298
2.

A CRISPR/Cas9-based strategy to simultaneously inactivate the entire ALS gene family in Candida orthopsilosis.

Zoppo M, Di Luca M, Villarreal SN, Poma N, Barrasa MI, Bottai D, Vyas VK, Tavanti A.

Future Microbiol. 2019 Oct 29. doi: 10.2217/fmb-2019-0168. [Epub ahead of print]

PMID:
31659913
3.

Brain cancer-activated microglia: A potential role for sphingolipids.

Bottai D, Adami R, Paroni R, Ghidoni R.

Curr Med Chem. 2019 May 6. doi: 10.2174/0929867326666190506120213. [Epub ahead of print]

PMID:
31057101
4.

Characterization of the Candida orthopsilosis agglutinin-like sequence (ALS) genes.

Lombardi L, Zoppo M, Rizzato C, Bottai D, Hernandez AG, Hoyer LL, Tavanti A.

PLoS One. 2019 Apr 24;14(4):e0215912. doi: 10.1371/journal.pone.0215912. eCollection 2019.

5.

The crosstalk between glycosphingolipids and neural stem cells.

Bottai D, Adami R, Ghidoni R.

J Neurochem. 2019 Mar;148(6):698-711. doi: 10.1111/jnc.14600. Epub 2018 Dec 3. Review.

PMID:
30269334
6.

Modeling Cornelia de Lange syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation.

Bottai D, Spreafico M, Pistocchi A, Fazio G, Adami R, Grazioli P, Canu A, Bragato C, Rigamonti S, Parodi C, Cazzaniga G, Biondi A, Cotelli F, Selicorni A, Massa V.

Hum Mol Genet. 2019 Jan 1;28(1):64-73. doi: 10.1093/hmg/ddy329.

PMID:
30239720
7.

CORT0C04210 is required for Candida orthopsilosis adhesion to human buccal cells.

Zoppo M, Lombardi L, Rizzato C, Lupetti A, Bottai D, Papp C, Gácser A, Tavanti A.

Fungal Genet Biol. 2018 Nov;120:19-29. doi: 10.1016/j.fgb.2018.09.001. Epub 2018 Sep 8.

PMID:
30205198
8.

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.

Ates LS, Sayes F, Frigui W, Ummels R, Damen MPM, Bottai D, Behr MA, van Heijst JWJ, Bitter W, Majlessi L, Brosch R.

PLoS Pathog. 2018 Jun 18;14(6):e1007139. doi: 10.1371/journal.ppat.1007139. eCollection 2018 Jun.

9.

Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics.

Adami R, Pagano J, Colombo M, Platonova N, Recchia D, Chiaramonte R, Bottinelli R, Canepari M, Bottai D.

Front Neurosci. 2018 May 23;12:336. doi: 10.3389/fnins.2018.00336. eCollection 2018.

10.

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.

Sayes F, Blanc C, Ates LS, Deboosere N, Orgeur M, Le Chevalier F, Gröschel MI, Frigui W, Song OR, Lo-Man R, Brossier F, Sougakoff W, Bottai D, Brodin P, Charneau P, Brosch R, Majlessi L.

Cell Rep. 2018 Apr 24;23(4):1072-1084. doi: 10.1016/j.celrep.2018.03.125.

11.

CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates.

Rizzato C, Poma N, Zoppo M, Posteraro B, Mello E, Bottai D, Lupetti A, Sanguinetti M, Tavanti A.

J Antimicrob Chemother. 2018 Jul 1;73(7):1815-1822. doi: 10.1093/jac/dky122.

PMID:
29635519
12.

The N-Terminus of Human Lactoferrin Displays Anti-biofilm Activity on Candida parapsilosis in Lumen Catheters.

Fais R, Di Luca M, Rizzato C, Morici P, Bottai D, Tavanti A, Lupetti A.

Front Microbiol. 2017 Nov 13;8:2218. doi: 10.3389/fmicb.2017.02218. eCollection 2017.

13.

Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia.

Marsoner F, Marcatili M, Karnavas T, Bottai D, D'Agostino A, Scarone S, Conti L.

Stem Cell Res. 2016 Nov;17(3):661-664. doi: 10.1016/j.scr.2016.11.005. Epub 2016 Nov 10.

14.

Establishment of an induced pluripotent stem cell (iPSC) line from a patient with Clozapine-responder Schizophrenia.

Marcatili M, Marsoner F, D'Agostino A, Karnavas T, Bottai D, Scarone S, Conti L.

Stem Cell Res. 2016 Nov;17(3):630-633. doi: 10.1016/j.scr.2016.11.009. Epub 2016 Nov 9.

15.

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection.

Sayes F, Pawlik A, Frigui W, Gröschel MI, Crommelynck S, Fayolle C, Cia F, Bancroft GJ, Bottai D, Leclerc C, Brosch R, Majlessi L.

PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770. eCollection 2016 Jul.

16.

The BCG Strain Pool: Diversity Matters.

Bottai D, Brosch R.

Mol Ther. 2016 Feb;24(2):201-203. doi: 10.1038/mt.2016.18. No abstract available.

17.

Type VII Secretion Systems in Gram-Positive Bacteria.

Bottai D, Gröschel MI, Brosch R.

Curr Top Microbiol Immunol. 2017;404:235-265. doi: 10.1007/82_2015_5015. Review.

PMID:
26847354
18.

Movement impairment: Focus on the brain.

Adami R, Bottai D.

J Neurosci Res. 2016 Apr;94(4):310-7. doi: 10.1002/jnr.23711. Epub 2016 Jan 13. Review.

PMID:
26762181
19.

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis.

Le Chevalier F, Cascioferro A, Frigui W, Pawlik A, Boritsch EC, Bottai D, Majlessi L, Herrmann JL, Brosch R.

Sci Rep. 2015 Nov 25;5:16918. doi: 10.1038/srep16918.

20.

Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions.

Etna MP, Giacomini E, Pardini M, Severa M, Bottai D, Cruciani M, Rizzo F, Calogero R, Brosch R, Coccia EM.

Sci Rep. 2015 Nov 25;5:17078. doi: 10.1038/srep17078.

21.

The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.

Slama N, Jamet S, Frigui W, Pawlik A, Bottai D, Laval F, Constant P, Lemassu A, Cam K, Daffé M, Brosch R, Eynard N, Quémard A.

Mol Microbiol. 2016 Feb;99(4):794-807. doi: 10.1111/mmi.13266. Epub 2015 Nov 27.

22.

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system.

Bottai D, Frigui W, Clark S, Rayner E, Zelmer A, Andreu N, de Jonge MI, Bancroft GJ, Williams A, Brodin P, Brosch R.

Vaccine. 2015 May 28;33(23):2710-8. doi: 10.1016/j.vaccine.2015.03.083. Epub 2015 Apr 11.

PMID:
25869896
23.

ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection.

Simeone R, Bottai D, Frigui W, Majlessi L, Brosch R.

Tuberculosis (Edinb). 2015 Jun;95 Suppl 1:S150-4. doi: 10.1016/j.tube.2015.02.019. Epub 2015 Feb 13.

PMID:
25732627
24.

Stem cell transplantation in neurological diseases: improving effectiveness in animal models.

Adami R, Scesa G, Bottai D.

Front Cell Dev Biol. 2014 May 14;2:17. doi: 10.3389/fcell.2014.00017. eCollection 2014. Review.

25.

Inhibitory effect of the human liver-derived antimicrobial peptide hepcidin 20 on biofilms of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains of Staphylococcus epidermidis.

Brancatisano FL, Maisetta G, Di Luca M, Esin S, Bottai D, Bizzarri R, Campa M, Batoni G.

Biofouling. 2014;30(4):435-46. doi: 10.1080/08927014.2014.888062. Epub 2014 Mar 19.

PMID:
24645694
26.

Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.

Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Wu TD, Poincloux R, Brosch R, Guerquin-Kern JL, Schnappinger D, Sório de Carvalho LP, Poquet Y, Neyrolles O.

PLoS Pathog. 2014 Feb 20;10(2):e1003928. doi: 10.1371/journal.ppat.1003928. eCollection 2014 Feb.

27.

Third trimester NG2-positive amniotic fluid cells are effective in improving repair in spinal cord injury.

Bottai D, Scesa G, Cigognini D, Adami R, Nicora E, Abrignani S, Di Giulio AM, Gorio A.

Exp Neurol. 2014 Apr;254:121-33. doi: 10.1016/j.expneurol.2014.01.015. Epub 2014 Jan 29.

PMID:
24485983
28.

Mycobacterial Pathogenomics and Evolution.

Bottai D, Stinear TP, Supply P, Brosch R.

Microbiol Spectr. 2014 Feb;2(1):MGM2-0025-2013. doi: 10.1128/microbiolspec.MGM2-0025-2013. Review.

PMID:
26082120
29.

Targeting type VII/ESX secretion systems for development of novel antimycobacterial drugs.

Bottai D, Serafini A, Cascioferro A, Brosch R, Manganelli R.

Curr Pharm Des. 2014;20(27):4346-56. Review.

PMID:
24245757
30.

Spinal muscular atrophy: new findings for an old pathology.

Bottai D, Adami R.

Brain Pathol. 2013 Nov;23(6):613-22. doi: 10.1111/bpa.12071. Epub 2013 Jun 28. Review.

PMID:
23750936
31.

Interaction of Mycobacterium tuberculosis cell wall components with the human natural killer cell receptors NKp44 and Toll-like receptor 2.

Esin S, Counoupas C, Aulicino A, Brancatisano FL, Maisetta G, Bottai D, Di Luca M, Florio W, Campa M, Batoni G.

Scand J Immunol. 2013 Jun;77(6):460-9. doi: 10.1111/sji.12052.

32.

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability.

Di Luca M, Bottai D, Batoni G, Orgeur M, Aulicino A, Counoupas C, Campa M, Brosch R, Esin S.

PLoS One. 2012;7(12):e52059. doi: 10.1371/journal.pone.0052059. Epub 2012 Dec 17.

33.

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria.

Houben D, Demangel C, van Ingen J, Perez J, Baldeón L, Abdallah AM, Caleechurn L, Bottai D, van Zon M, de Punder K, van der Laan T, Kant A, Bossers-de Vries R, Willemsen P, Bitter W, van Soolingen D, Brosch R, van der Wel N, Peters PJ.

Cell Microbiol. 2012 Aug;14(8):1287-98. doi: 10.1111/j.1462-5822.2012.01799.x. Epub 2012 May 8.

PMID:
22524898
34.

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential.

Sayes F, Sun L, Di Luca M, Simeone R, Degaiffier N, Fiette L, Esin S, Brosch R, Bottai D, Leclerc C, Majlessi L.

Cell Host Microbe. 2012 Apr 19;11(4):352-63. doi: 10.1016/j.chom.2012.03.003.

35.

Third trimester amniotic fluid cells with the capacity to develop neural phenotypes and with heterogeneity among sub-populations.

Bottai D, Cigognini D, Nicora E, Moro M, Grimoldi MG, Adami R, Abrignani S, Marconi AM, Di Giulio AM, Gorio A.

Restor Neurol Neurosci. 2012;30(1):55-68. doi: 10.3233/RNN-2011-0620.

PMID:
22377907
36.

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.

Bottai D, Di Luca M, Majlessi L, Frigui W, Simeone R, Sayes F, Bitter W, Brennan MJ, Leclerc C, Batoni G, Campa M, Brosch R, Esin S.

Mol Microbiol. 2012 Mar;83(6):1195-209. doi: 10.1111/j.1365-2958.2012.08001.x. Epub 2012 Feb 20.

37.

Adult neural precursors isolated from post mortem brain yield mostly neurons: an erythropoietin-dependent process.

Marfia G, Madaschi L, Marra F, Menarini M, Bottai D, Formenti A, Bellardita C, Di Giulio AM, Carelli S, Gorio A.

Neurobiol Dis. 2011 Jul;43(1):86-98. doi: 10.1016/j.nbd.2011.02.004. Epub 2011 Feb 13.

PMID:
21324364
38.

ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.

Bottai D, Majlessi L, Simeone R, Frigui W, Laurent C, Lenormand P, Chen J, Rosenkrands I, Huerre M, Leclerc C, Cole ST, Brosch R.

J Infect Dis. 2011 Apr 15;203(8):1155-64. doi: 10.1093/infdis/jiq089. Epub 2010 Dec 31.

PMID:
21196469
39.

Embryonic stem cells promote motor recovery and affect inflammatory cell infiltration in spinal cord injured mice.

Bottai D, Cigognini D, Madaschi L, Adami R, Nicora E, Menarini M, Di Giulio AM, Gorio A.

Exp Neurol. 2010 Jun;223(2):452-63. doi: 10.1016/j.expneurol.2010.01.010. Epub 2010 Jan 25.

PMID:
20100476
40.

The BCG1619c gene is not essential for invasion and intracellular persistence of Mycobacterium bovis BCG in human THP-1 and A549 cell lines.

Florio W, Brancatisano FL, Bottai D, Esin S, Di Luca M, Counoupas C, Maisetta G, Lupetti A, Batoni G, Campa M.

Can J Microbiol. 2009 Aug;55(8):975-82. doi: 10.1139/w09-053.

PMID:
19898537
41.

Systematic genetic nomenclature for type VII secretion systems.

Bitter W, Houben EN, Bottai D, Brodin P, Brown EJ, Cox JS, Derbyshire K, Fortune SM, Gao LY, Liu J, Gey van Pittius NC, Pym AS, Rubin EJ, Sherman DR, Cole ST, Brosch R.

PLoS Pathog. 2009 Oct;5(10):e1000507. doi: 10.1371/journal.ppat.1000507. Epub 2009 Oct 30. No abstract available.

42.

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families.

Bottai D, Brosch R.

Mol Microbiol. 2009 Aug;73(3):325-8. doi: 10.1111/j.1365-2958.2009.06784.x. Epub 2009 Jul 7.

43.

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants.

Gordon SV, Bottai D, Simeone R, Stinear TP, Brosch R.

Bioessays. 2009 Apr;31(4):378-88. doi: 10.1002/bies.200800191. Review.

PMID:
19274661
44.

ESX/type VII secretion systems and their role in host-pathogen interaction.

Simeone R, Bottai D, Brosch R.

Curr Opin Microbiol. 2009 Feb;12(1):4-10. doi: 10.1016/j.mib.2008.11.003. Epub 2009 Jan 18. Review.

PMID:
19155186
45.

Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction.

Givogri MI, Bottai D, Zhu HL, Fasano S, Lamorte G, Brambilla R, Vescovi A, Wrabetz L, Bongarzone E.

Dev Neurosci. 2008;30(5):340-57. doi: 10.1159/000150127. Epub 2008 Jul 30. Erratum in: Dev Neurosci. 2008;30(5):357.

PMID:
18667806
46.

Viability-dependent promoting action of adult neural precursors in spinal cord injury.

Bottai D, Madaschi L, Di Giulio AM, Gorio A.

Mol Med. 2008 Sep-Oct;14(9-10):634-44. doi: 10.2119/2008-00077.Bottai.

47.

The stem cells as a potential treatment for neurodegeneration.

Daniela F, Vescovi AL, Bottai D.

Methods Mol Biol. 2007;399:199-213. doi: 10.1007/978-1-59745-504-6_14. Review.

PMID:
18309934
48.

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.

Frigui W, Bottai D, Majlessi L, Monot M, Josselin E, Brodin P, Garnier T, Gicquel B, Martin C, Leclerc C, Cole ST, Brosch R.

PLoS Pathog. 2008 Feb 8;4(2):e33. doi: 10.1371/journal.ppat.0040033.

49.

Acrylate end-capped poly(ester-carbonate) and poly(ether-ester)s for polymer-on-multielectrode array devices: synthesis, photocuring, and biocompatibility.

Henry GR, Heise A, Bottai D, Formenti A, Gorio A, Di Giulio AM, Koning CE.

Biomacromolecules. 2008 Mar;9(3):867-78. doi: 10.1021/bm701191e. Epub 2008 Feb 8.

PMID:
18257527
50.

Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3.

Maisetta G, Di Luca M, Esin S, Florio W, Brancatisano FL, Bottai D, Campa M, Batoni G.

Peptides. 2008 Jan;29(1):1-6. Epub 2007 Oct 24.

PMID:
18045738

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