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CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.

Hwang JH, Seo JH, Beshiri ML, Wankowicz S, Liu D, Cheung A, Li J, Qiu X, Hong AL, Botta G, Golumb L, Richter C, So J, Sandoval GJ, Giacomelli AO, Ly SH, Han C, Dai C, Pakula H, Sheahan A, Piccioni F, Gjoerup O, Loda M, Sowalsky AG, Ellis L, Long H, Root DE, Kelly K, Van Allen EM, Freedman ML, Choudhury AD, Hahn WC.

Cell Rep. 2019 Nov 19;29(8):2355-2370.e6. doi: 10.1016/j.celrep.2019.10.068.


Two autopsy cases of siblings with alveolar capillary dysplasia: clinical and post-mortem issues.

Petetta C, Tattoli L, Botta G, Di Vella G.

Forensic Sci Med Pathol. 2019 Sep 11. doi: 10.1007/s12024-019-00153-y. [Epub ahead of print]


Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue.

Spadaro M, Martire S, Marozio L, Mastromauro D, Montanari E, Perga S, Montarolo F, Brescia F, Balbo A, Botta G, Benedetto C, Bertolotto A.

Front Immunol. 2019 Aug 16;10:1935. doi: 10.3389/fimmu.2019.01935. eCollection 2019.


Infantile Hypertrophic Cardiomyopathy and Bronchopneumonia as Causes of an Unexpected Death in an 11-Month-Old Child.

Lupariello F, Di Vella G, Botta G.

Fetal Pediatr Pathol. 2019 Aug 26:1-3. doi: 10.1080/15513815.2019.1655820. [Epub ahead of print]


Death Shortly after Delivery Caused by Congenital High Airway Obstruction Syndrome.

Lupariello F, Di Vella G, Botta G.

Fetal Pediatr Pathol. 2019 Jul 25:1-5. doi: 10.1080/15513815.2019.1644688. [Epub ahead of print]


Evaluating human basal metabolism: the erroneous and misleading use of so-called "prediction equations".

Bottà G, Binelli G, Agostoni C, Aliverti A, Scarì G, Manenti R, La Vecchia C.

Int J Food Sci Nutr. 2020 Mar;71(2):249-255. doi: 10.1080/09637486.2019.1641472. Epub 2019 Jul 17.


Micro-computed tomography: a new diagnostic tool in postmortem assessment of brain anatomy in small fetuses.

Lombardi S, Scola E, Ippolito D, Zambelli V, Botta G, Cuttin S, Triulzi F, Lombardi CM.

Neuroradiology. 2019 Jul;61(7):737-746. doi: 10.1007/s00234-019-02168-2. Epub 2019 Jan 28.


Birth defects surveillance: experiences in Argentina and Colombia.

Groisman B, Liascovich R, Bidondo MP, Barbero P, Duarte S, Tellechea AL, Holguín J, Rodríguez C, Hurtado-Villa P, Caicedo N, Botta G, Zarante I.

J Community Genet. 2019 Jul;10(3):385-393. doi: 10.1007/s12687-018-00403-6. Epub 2019 Jan 3.


Hemorrhagic Cystitis: Treatment With Hyperbaric Oxygen Therapy in Patients With Acute Lymphoblastic Leukemia.

Botta LM, Botta GP.

Clin J Oncol Nurs. 2018 Dec 1;22(6):E146-E151. doi: 10.1188/18.CJON.E146-E151. Review.


A fetal case of microphthalmia and limb anomalies with abnormal neuronal migration associated with SMOC1 biallelic variants.

Mancini C, Zonta A, Botta G, Breda Klobus A, Valbonesi S, Pasini B, Giorgio E, Viora E, Brusco A, Brussino A.

Eur J Med Genet. 2019 Nov;62(11):103578. doi: 10.1016/j.ejmg.2018.11.012. Epub 2018 Nov 13.


Reversible intrahepatic cholestasis in metastatic prostate cancer: An uncommon paraneoplastic syndrome.

Bhangoo MS, Cheng B, Botta GP, Thorson P, Kosty MP.

Mol Clin Oncol. 2018 Apr;8(4):613-616. doi: 10.3892/mco.2018.1564. Epub 2018 Feb 2.


Autolytic debridement and management of bacterial load with an occlusive hydroactive deressing impregnated with polyhexamethylene biguanide.

Mancini S, Cuomo R, Poggialini M, D'Aniello C, Botta G.

Acta Biomed. 2018 Jan 16;88(4):409-413. doi: 10.23750/abm.v88i4.5802.


Advances on immunotherapy in genitourinary and renal cell carcinoma.

Botta GP, Granowicz E, Costantini C.

Transl Cancer Res. 2017 Feb;6(1):17-29. doi: 10.21037/tcr.2017.02.09.


High-resolution MR lymphangiography for planning lymphaticovenous anastomosis treatment: a single-centre experience.

Mazzei MA, Gentili F, Mazzei FG, Gennaro P, Guerrieri D, Nigri A, Gabriele G, Weber E, Fausto A, Botta G, Volterrani L.

Radiol Med. 2017 Dec;122(12):918-927. doi: 10.1007/s11547-017-0795-x. Epub 2017 Aug 2.


Association between genital mycoplasmas, acute chorioamnionitis and fetal pneumonia in spontaneous abortions.

Latino MA, Botta G, Badino C, Maria D, Petrozziello A, Sensini A, Leli C.

J Perinat Med. 2018 Jul 26;46(5):503-508. doi: 10.1515/jpm-2016-0305.


Massive introgression drives species radiation at the range limit of Anopheles gambiae.

Vicente JL, Clarkson CS, Caputo B, Gomes B, Pombi M, Sousa CA, Antao T, Dinis J, Bottà G, Mancini E, Petrarca V, Mead D, Drury E, Stalker J, Miles A, Kwiatkowski DP, Donnelly MJ, Rodrigues A, Torre AD, Weetman D, Pinto J.

Sci Rep. 2017 Apr 18;7:46451. doi: 10.1038/srep46451.


Glutathione S-transferase M1 null genotype, household pesticides exposure and cutaneous melanoma.

Fortes C, Mastroeni S, Bottà G, Boffetta P, Antonelli G, Venanzetti F.

Melanoma Res. 2016 Dec;26(6):625-630.


Extensive Myocardial Infarction in a Fetus With Cystic Fibrosis and Meconium Peritonitis.

Terlizzi V, Sciarrone A, Cook AC, Botta G, Chiappa E.

J Ultrasound Med. 2016 Aug;35(8):1826-8. doi: 10.7863/ultra.15.09037. No abstract available.


Spontaneous Iliopsoas Muscle Hemorrhage Secondary to Ibrutinib (Imbruvica; Pharmacyclics): Brief Report.

Sarcon A, Botta GP, Patel N, Saven A.

J Investig Med High Impact Case Rep. 2016 May 9;4(2):2324709616648457. doi: 10.1177/2324709616648457. eCollection 2016 Apr-Jun.


A Global Scale Scenario for Prebiotic Chemistry: Silica-Based Self-Assembled Mineral Structures and Formamide.

Saladino R, Botta G, Bizzarri BM, Di Mauro E, Garcia Ruiz JM.

Biochemistry. 2016 May 17;55(19):2806-11. doi: 10.1021/acs.biochem.6b00255. Epub 2016 May 2.


First Evidence on the Role of Heavy Ion Irradiation of Meteorites and Formamide in the Origin of Biomolecules.

Saladino R, Carota E, Botta G, Kapralov M, Timoshenko GN, Rozanov A, Krasavin E, Di Mauro E.

Orig Life Evol Biosph. 2016 Nov;46(4):515-521. Epub 2016 Apr 6.


Assessment of the Effectiveness of a Seasonal-Long Insecticide-Based Control Strategy against Aedes albopictus Nuisance in an Urban Area.

Caputo B, Manica M, D'Alessandro A, Bottà G, Filipponi F, Protano C, Vitali M, Rosà R, della Torre A.

PLoS Negl Trop Dis. 2016 Mar 3;10(3):e0004463. doi: 10.1371/journal.pntd.0004463. eCollection 2016 Mar.


Free radical scavenging capacity and protective effect of natural substances in peloids from the thermal spring pool Bagnaccio (Viterbo, Italy).

Saladino R, Chiocchini U, Botta G, Delfino M, Conigliaro R, Mosesso P.

J Cosmet Sci. 2016 Mar-Apr;67(2):71-92.


Array-Comparative Genomic Hybridization Analysis in Fetuses with Major Congenital Malformations Reveals that 24% of Cases Have Pathogenic Deletions/Duplications.

Di Gregorio E, Gai G, Botta G, Calcia A, Pappi P, Talarico F, Savin E, Ribotta M, Zonta A, Mancini C, Giorgio E, Cavalieri S, Restagno G, Ferrero GB, Viora E, Pasini B, Grosso E, Brusco A, Brussino A.

Cytogenet Genome Res. 2015;147(1):10-6. doi: 10.1159/000442308. Epub 2015 Dec 12.


Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses.

Botta G, Bizzarri BM, Garozzo A, Timpanaro R, Bisignano B, Amatore D, Palamara AT, Nencioni L, Saladino R.

Bioorg Med Chem. 2015 Sep 1;23(17):5345-51. doi: 10.1016/j.bmc.2015.07.061. Epub 2015 Jul 30.


Current Advances in L-DOPA and DOPA-Peptidomimetics: Chemistry, Applications and Biological Activity.

Bizzarri BM, Tortolini S, Rotelli L, Botta G, Saladino R.

Curr Med Chem. 2015;22(36):4138-65. Review.


Accuracy of ultrasound in antenatal diagnosis of placental attachment disorders.

Pilloni E, Alemanno MG, Gaglioti P, Sciarrone A, Garofalo A, Biolcati M, Botta G, Viora E, Todros T.

Ultrasound Obstet Gynecol. 2016 Mar;47(3):302-7. doi: 10.1002/uog.14893. Epub 2016 Feb 9.


Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation.

Saladino R, Carota E, Botta G, Kapralov M, Timoshenko GN, Rozanov AY, Krasavin E, Di Mauro E.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2746-55. doi: 10.1073/pnas.1422225112. Epub 2015 Apr 13.


PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.

Hsieh CL, Botta G, Gao S, Li T, Van Allen EM, Treacy DJ, Cai C, He HH, Sweeney CJ, Brown M, Balk SP, Nelson PS, Garraway LA, Kantoff PW.

Cancer Res. 2015 May 15;75(10):1944-8. doi: 10.1158/0008-5472.CAN-14-3602. Epub 2015 Mar 25.


Large cryptic genomic rearrangements with apparently normal karyotypes detected by array-CGH.

Di Gregorio E, Savin E, Biamino E, Belligni EF, Naretto VG, D'Alessandro G, Gai G, Fiocchi F, Calcia A, Mancini C, Giorgio E, Cavalieri S, Talarico F, Pappi P, Gandione M, Grosso M, Asnaghi V, Restagno G, Mandrile G, Botta G, Silengo MC, Grosso E, Ferrero GB, Brusco A.

Mol Cytogenet. 2014 Nov 19;7(1):82. doi: 10.1186/s13039-014-0082-7. eCollection 2014.


PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma.

Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, Libertini S, Portella G.

Mol Oncol. 2015 Jan;9(1):78-92. doi: 10.1016/j.molonc.2014.07.022. Epub 2014 Aug 2.


Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes.

Rotili D, Tarantino D, Nawrozkij MB, Babushkin AS, Botta G, Marrocco B, Cirilli R, Menta S, Badia R, Crespan E, Ballante F, Ragno R, Esté JA, Maga G, Mai A.

J Med Chem. 2014 Jun 26;57(12):5212-25. doi: 10.1021/jm500284x. Epub 2014 Jun 16.


Postmortem microcomputed tomography (micro-CT) of small fetuses and hearts.

Lombardi CM, Zambelli V, Botta G, Moltrasio F, Cattoretti G, Lucchini V, Fesslova V, Cuttin MS.

Ultrasound Obstet Gynecol. 2014 Nov;44(5):600-9. doi: 10.1002/uog.13330. Epub 2014 Oct 13.


Right gastroepiploic artery arising from the dorsal pancreatic artery: a very rare anatomic variation underlying interesting embryologic implications.

Di Gregorio F, Regoli M, Botta G, Bertelli E.

Surg Radiol Anat. 2015 Jan;37(1):109-14. doi: 10.1007/s00276-014-1273-y. Epub 2014 Mar 2.


Cephalopods in neuroscience: regulations, research and the 3Rs.

Fiorito G, Affuso A, Anderson DB, Basil J, Bonnaud L, Botta G, Cole A, D'Angelo L, De Girolamo P, Dennison N, Dickel L, Di Cosmo A, Di Cristo C, Gestal C, Fonseca R, Grasso F, Kristiansen T, Kuba M, Maffucci F, Manciocco A, Mark FC, Melillo D, Osorio D, Palumbo A, Perkins K, Ponte G, Raspa M, Shashar N, Smith J, Smith D, Sykes A, Villanueva R, Tublitz N, Zullo L, Andrews P.

Invert Neurosci. 2014 Mar;14(1):13-36. doi: 10.1007/s10158-013-0165-x. Epub 2014 Jan 3. Review.


Meteorites as catalysts for prebiotic chemistry.

Saladino R, Botta G, Delfino M, Di Mauro E.

Chemistry. 2013 Dec 9;19(50):16916-22. doi: 10.1002/chem.201303690. Epub 2013 Nov 7. No abstract available.


Tyrosinase and Layer-by-Layer supported tyrosinases in the synthesis of lipophilic catechols with antiinfluenza activity.

Bozzini T, Botta G, Delfino M, Onofri S, Saladino R, Amatore D, Sgarbanti R, Nencioni L, Palamara AT.

Bioorg Med Chem. 2013 Dec 15;21(24):7699-708. doi: 10.1016/j.bmc.2013.10.026. Epub 2013 Oct 30.


Fetal thrombotic vasculopathy and perinatal thrombosis: should all placentas be examined?

Magnetti F, Bagna R, Botta G, Viano A, Dorati G, Raia M, Bertino E, Saracco P.

Am J Perinatol. 2014 Sep;31(8):695-700. doi: 10.1055/s-0033-1357267. Epub 2013 Oct 9.


The protective effect of coffee consumption on cutaneous melanoma risk and the role of GSTM1 and GSTT1 polymorphisms.

Fortes C, Mastroeni S, Boffetta P, Antonelli G, Pilla MA, Bottà G, Anzidei P, Venanzetti F.

Cancer Causes Control. 2013 Oct;24(10):1779-87. doi: 10.1007/s10552-013-0255-4. Epub 2013 Jul 17.


Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells.

Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G.

Endocr Relat Cancer. 2013 Aug 19;20(5):633-47. doi: 10.1530/ERC-13-0001. Print 2013 Oct.


Isolation, culture and genetic manipulation of mouse pancreatic ductal cells.

Reichert M, Takano S, Heeg S, Bakir B, Botta GP, Rustgi AK.

Nat Protoc. 2013;8(7):1354-65. doi: 10.1038/nprot.2013.079. Epub 2013 Jun 20.


Materials for the onset. A story of necessity and chance.

Saladino R, Botta G, Pino S, Costanzo G, Di Mauro E.

Front Biosci (Landmark Ed). 2013 Jun 1;18:1275-89. Review.


ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.

Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK, Lelkes PI.

Neoplasia. 2013 Apr;15(4):359-72.


Life-threatening tumors of the heart in fetal and postnatal age.

Pucci A, Botta G, Sina N, Tibaldi M, Valori A, Grosso E, Zonta A, Giudici M, Agnoletti G, Bergamasco L, Abbruzzese PA, Bartoloni G.

J Pediatr. 2013 May;162(5):964-9.e1. doi: 10.1016/j.jpeds.2012.10.055. Epub 2012 Dec 7.


Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.

Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, Fraga M, Esteller M, Altucci L, Mai A.

J Med Chem. 2012 Dec 27;55(24):10937-47. doi: 10.1021/jm3011614. Epub 2012 Dec 12.


Emergence and spread of antimicrobial-resistant pathogens in an era of globalization.

Senok AC, Botta GA, Soge OO.

Interdiscip Perspect Infect Dis. 2012;2012:286703. doi: 10.1155/2012/286703. Epub 2012 Oct 16. No abstract available.


Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering.

Frohbergh ME, Katsman A, Botta GP, Lazarovici P, Schauer CL, Wegst UG, Lelkes PI.

Biomaterials. 2012 Dec;33(36):9167-78. doi: 10.1016/j.biomaterials.2012.09.009. Epub 2012 Sep 27.


Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.

Rotili D, Tarantino D, Carafa V, Paolini C, Schemies J, Jung M, Botta G, Di Maro S, Novellino E, Steinkühler C, De Maria R, Gallinari P, Altucci L, Mai A.

J Med Chem. 2012 Sep 27;55(18):8193-7. Epub 2012 Sep 7.


From the one-carbon amide formamide to RNA all the steps are prebiotically possible.

Saladino R, Botta G, Pino S, Costanzo G, Di Mauro E.

Biochimie. 2012 Jul;94(7):1451-6. doi: 10.1016/j.biochi.2012.02.018. Epub 2012 Feb 22. Review.


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