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Items: 47

1.

PD-1H (VISTA)-mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus.

Han X, Vesely MD, Yang W, Sanmamed MF, Badri T, Alawa J, López-Giráldez F, Gaule P, Lee SW, Zhang JP, Nie X, Nassar A, Boto A, Flies DB, Zheng L, Kim TK, Moeckel GW, McNiff JM, Chen L.

Sci Transl Med. 2019 Dec 11;11(522). pii: eaax1159. doi: 10.1126/scitranslmed.aax1159.

PMID:
31826980
2.

Conversion of "Customizable Units" into N-Alkyl Amino Acids and Generation of N-Alkyl Peptides.

Saavedra CJ, Carro C, Hernández D, Boto A.

J Org Chem. 2019 Jul 5;84(13):8392-8410. doi: 10.1021/acs.joc.9b00114. Epub 2019 Jun 24.

PMID:
31120247
3.

Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy.

Wang J, Sun J, Liu LN, Flies DB, Nie X, Toki M, Zhang J, Song C, Zarr M, Zhou X, Han X, Archer KA, O'Neill T, Herbst RS, Boto AN, Sanmamed MF, Langermann S, Rimm DL, Chen L.

Nat Med. 2019 Apr;25(4):656-666. doi: 10.1038/s41591-019-0374-x. Epub 2019 Mar 4.

PMID:
30833750
4.

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.

Wang J, Sanmamed MF, Datar I, Su TT, Ji L, Sun J, Chen L, Chen Y, Zhu G, Yin W, Zheng L, Zhou T, Badri T, Yao S, Zhu S, Boto A, Sznol M, Melero I, Vignali DAA, Schalper K, Chen L.

Cell. 2019 Jan 10;176(1-2):334-347.e12. doi: 10.1016/j.cell.2018.11.010. Epub 2018 Dec 20.

5.

Hormone producing gynecological tumors: pathologic entities and clinical significance.

Boto AN, Hui P.

Expert Rev Endocrinol Metab. 2018 Jan;13(1):9-24. doi: 10.1080/17446651.2018.1411799. Epub 2017 Dec 7. Review.

PMID:
30063444
6.

Acute arterial embolism as the clinical presentation of a disseminated hydatidosis: case report.

Rossetti E, Boto A, González Cambaceres C, Ruvinsky S, Sagray E; Colaboradores.

Arch Argent Pediatr. 2018 Aug 1;116(4):e616-e620. doi: 10.5546/aap.2018.eng.e616. English, Spanish.

7.

Strong androgen receptor expression can aid in distinguishing GATA3+ metastases.

Boto A, Harigopal M.

Hum Pathol. 2018 May;75:63-70. doi: 10.1016/j.humpath.2018.01.024. Epub 2018 Feb 2.

PMID:
29408697
8.

The Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs.

Boto A, Pérez de la Lastra JM, González CC.

Molecules. 2018 Feb 1;23(2). pii: E311. doi: 10.3390/molecules23020311. Review.

9.

Metal-Free, Site-Selective Peptide Modification by Conversion of "Customizable" Units into β-Substituted Dehydroamino Acids.

Saavedra CJ, Hernández D, Boto A.

Chemistry. 2018 Jan 12;24(3):599-607. doi: 10.1002/chem.201703758. Epub 2017 Dec 6.

PMID:
29048756
10.

Metal-free, direct conversion of α-amino acids into α-keto γ-amino esters for the synthesis of α,γ-peptides.

Hernández D, Boto A, Guzmán D, Alvarez E.

Org Biomol Chem. 2017 Sep 26;15(37):7736-7742. doi: 10.1039/c7ob02033c.

PMID:
28872167
11.

Colocalization of Estrogen Receptors with the Fluorescent Tamoxifen Derivative, FLTX1, Analyzed by Confocal Microscopy.

Morales A, Marín R, Marrero-Alonso J, Boto A, Díaz M.

Methods Mol Biol. 2016;1366:163-173. doi: 10.1007/978-1-4939-3127-9_13.

PMID:
26585134
12.

Domino Process Achieves Site-Selective Peptide Modification with High Optical Purity. Applications to Chain Diversification and Peptide Ligation.

Romero-Estudillo I, Boto A.

J Org Chem. 2015 Oct 2;80(19):9379-91. doi: 10.1021/acs.joc.5b00932. Epub 2015 Jul 20.

PMID:
26151417
13.

Site-selective modification of peptides: From "customizable units" to novel α-aryl and α-alkyl glycine derivatives, and components of branched peptides.

Romero-Estudillo I, Saavedra C, Boto A, Álvarez E.

Biopolymers. 2015 Sep;104(5):650-62. doi: 10.1002/bip.22642.

PMID:
25808670
14.

Regulation of the NaV1.5 cytoplasmic domain by calmodulin.

Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM.

Nat Commun. 2014 Nov 5;5:5126. doi: 10.1038/ncomms6126.

15.

Metal-free, one-pot conversion of proline derivatives into 2-aryl-3-iodo pyrrolidines by a sequential scission-iodination-arylation process.

Batchu VR, Romero-Estudillo I, Boto A, Miguélez J.

Org Biomol Chem. 2014 Dec 21;12(47):9547-56. doi: 10.1039/c4ob01372g. Epub 2014 Oct 21.

PMID:
25333212
16.

Unilateral punctate keratitis secondary to Wallenberg Syndrome.

Cidad P, Boto A, Del Hierro A, Capote M, Noval S, Garcia A, Santiago S.

Korean J Ophthalmol. 2014 Jun;28(3):278-83. doi: 10.3341/kjo.2014.28.3.278. Epub 2014 May 19.

17.

Creating diversity by site-selective peptide modification: a customizable unit affords amino acids with high optical purity.

Romero-Estudillo I, Boto A.

Org Lett. 2013 Nov 15;15(22):5778-81. doi: 10.1021/ol402800a. Epub 2013 Oct 30.

PMID:
24171384
18.

Simplification of antitumoral phenanthroindolizidine alkaloids: short synthesis of cytotoxic indolizidinone and pyrrolidine analogs.

Miguélez J, Boto A, Marín R, Díaz M.

Eur J Med Chem. 2013 Aug;66:540-54. doi: 10.1016/j.ejmech.2013.06.009. Epub 2013 Jun 18.

PMID:
23845713
19.

Unique SERM-like properties of the novel fluorescent tamoxifen derivative FLTX1.

Marrero-Alonso J, Morales A, García Marrero B, Boto A, Marín R, Cury D, Gómez T, Fernández-Pérez L, Lahoz F, Díaz M.

Eur J Pharm Biopharm. 2013 Nov;85(3 Pt B):898-910. doi: 10.1016/j.ejpb.2013.04.024. Epub 2013 May 31.

PMID:
23727370
20.

Whispering gallery mode laser based on antitumor drug-dye complex gain medium.

Lahoz F, Oton CJ, López D, Marrero-Alonso J, Boto A, Díaz M.

Opt Lett. 2012 Nov 15;37(22):4756-8.

PMID:
23164903
21.

Stereoselective conversion of sugar derivatives into C-nucleosides.

Miguélez J, Batchu VR, Boto A.

J Org Chem. 2012 Sep 7;77(17):7652-8. doi: 10.1021/jo301031t. Epub 2012 Aug 23.

PMID:
22897165
22.

"Customizable" units in di- and tripeptides: selective conversion into substituted dehydroamino acids.

Saavedra CJ, Boto A, Hernández R.

Org Lett. 2012 Jul 20;14(14):3788-91. doi: 10.1021/ol301676z. Epub 2012 Jul 11.

PMID:
22783874
23.

Conformation and chiral effects in α,β,α-tripeptides.

Saavedra CJ, Boto A, Hernández R, Miranda JI, Aizpurua JM.

J Org Chem. 2012 Jul 20;77(14):5907-13. doi: 10.1021/jo300892u. Epub 2012 Jul 10.

PMID:
22775557
24.

Synthesis of α,γ-peptide hybrids by selective conversion of glutamic acid units.

Saavedra CJ, Boto A, Hernández R.

Org Lett. 2012 Jul 6;14(13):3542-5. doi: 10.1021/ol301552c. Epub 2012 Jun 25.

PMID:
22731708
25.

Preparation of modified peptides: direct conversion of α-amino acids into β-amino aldehydes.

Saavedra CJ, Boto A, Hernández R.

Org Biomol Chem. 2012 Jun 14;10(22):4448-61. doi: 10.1039/c2ob25433f. Epub 2012 May 4.

PMID:
22555858
26.

Synthesis of indolizidinone analogues of cytotoxic alkaloids: monocyclic precursors are also active.

Boto A, Miguélez J, Marín R, Díaz M.

Bioorg Med Chem Lett. 2012 May 15;22(10):3402-7. doi: 10.1016/j.bmcl.2012.03.109. Epub 2012 Apr 7.

PMID:
22537449
27.

Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.

Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM.

Proteins. 2011 Aug;79(8):2455-66. doi: 10.1002/prot.23069. Epub 2011 Jun 2.

28.

One-pot stereoselective synthesis of 1,2-amino alcohol derivatives.

Boto A, Romero-Estudillo I.

Org Lett. 2011 Jul 1;13(13):3426-9. doi: 10.1021/ol201173a. Epub 2011 May 26.

PMID:
21615165
29.

Toward a resolution of a taxonomic enigma: first genetic analyses of Paradoxornis webbianus and Paradoxornis alphonsianus (Aves: Paradoxornithidae) from China and Italy.

Crottini A, Galimberti A, Boto A, Serra L, Liu Y, Yeung C, Yang X, Barbuto M, Casiraghi M.

Mol Phylogenet Evol. 2010 Dec;57(3):1312-8. doi: 10.1016/j.ympev.2010.09.009. Epub 2010 Sep 25.

PMID:
20884363
30.

Catalytic, one-pot synthesis of beta-amino acids from alpha-amino acids. Preparation of alpha,beta-peptide derivatives.

Saavedra C, Hernández R, Boto A, Alvarez E.

J Org Chem. 2009 Jul 3;74(13):4655-65. doi: 10.1021/jo9004487.

PMID:
19391617
31.

Efficient conversion of carbohydrates into 1-C-alditols: application to the synthesis of chiral gamma-substituted butenolides and bicyclic alkaloid analogues.

Boto A, Hernández D, Hernández R.

J Org Chem. 2008 Jul 18;73(14):5287-97. doi: 10.1021/jo800478a. Epub 2008 Jun 13. Erratum in: J Org Chem. 2008 Sep 5;73(17):6946.

PMID:
18549274
32.

One-pot synthesis of acyclic nucleosides from carbohydrate derivatives, by combination of tandem and sequential reactions.

Boto A, Hernández D, Hernández R, Alvarez E.

J Org Chem. 2007 Dec 7;72(25):9523-32. Epub 2007 Nov 7.

PMID:
17985924
33.

Synthesis of unnatural amino acids from serine derivatives by beta-fragmentation of primary alkoxyl radicals.

Boto A, Gallardo JA, Hernández D, Hernández R.

J Org Chem. 2007 Sep 14;72(19):7260-9. Epub 2007 Aug 15.

PMID:
17696478
34.

Short and efficient synthesis of chiral furyl carbinols from carbohydrates.

Boto A, Hernandez D, Hernandez R.

Org Lett. 2007 Apr 26;9(9):1721-4. Epub 2007 Mar 31.

PMID:
17397175
35.

Approaches to the quaternary stereocentre and to the heterocyclic core in diazonamide A using the Heck reaction and related coupling reactions.

Booker JE, Boto A, Churchill GH, Green CP, Ling M, Meek G, Prabhakaran J, Sinclair D, Blake AJ, Pattenden G.

Org Biomol Chem. 2006 Nov 21;4(22):4193-205.

PMID:
17312976
36.

Genotoxic activity of halogenated phenylglycine derivatives.

Boto A, Gallardo JA, Hernández R, Ledo F, Muñoz A, Murguía JR, Menacho-Márquez M, Orjales A, Saavedra CJ.

Bioorg Med Chem Lett. 2006 Dec 1;16(23):6073-7. Epub 2006 Sep 20.

PMID:
16990000
37.

Selective cleavage of methoxy protecting groups in carbohydrates.

Boto A, Hernández D, Hernández R, Suárez E.

J Org Chem. 2006 Mar 3;71(5):1938-48.

PMID:
16496979
38.

Efficient and selective removal of methoxy protecting groups in carbohydrates.

Boto A, Hernández D, Hernández R, Suárez E.

Org Lett. 2004 Oct 14;6(21):3785-8.

PMID:
15469349
40.

Apolipoprotein D expression in retinoblastoma.

Alvarez ML, Barbón JJ, González LO, Abelairas J, Boto A, Vizoso F.

Ophthalmic Res. 2003 Mar-Apr;35(2):111-6.

PMID:
12646752
41.

Synthesis of 2,3-disubstituted pyrrolidines and piperidines via one-pot oxidative decarboxylation-beta-iodination of amino acids.

Boto A, Hernández R, de León Y, Suárez E.

J Org Chem. 2001 Nov 16;66(23):7796-803.

PMID:
11701038
42.

Quantum interferometric optical lithography: exploiting entanglement to beat the diffraction limit

Boto AN, Kok P, Abrams DS, Braunstein SL, Williams CP, Dowling JP.

Phys Rev Lett. 2000 Sep 25;85(13):2733-6.

PMID:
10991220
44.

Tandem beta-Fragmentation-Hydrogen Abstraction Reaction of Alkoxy Radicals in Steroidal Systems.

Boto A, Freire R, Hernández R, Suárez E, Rodríguez MS.

J Org Chem. 1997 May 2;62(9):2975-2981.

PMID:
11671662
45.

Haemolytic-uraemic syndrome in a patient infected by HIV.

Benitez M, Boto A, Colchero J, Fernandez-Girón F, Rodriguez P, Paralle M, Pujol E.

Nephrol Dial Transplant. 1997 Feb;12(2):362-3. No abstract available.

PMID:
9132665
46.

Haemophilus aphrophilus as a rare cause of arthritis.

Merino D, Saavedra J, Pujol E, Vega D, Colchero J, Boto A, Pascual L.

Clin Infect Dis. 1994 Aug;19(2):320-2. Review.

PMID:
7986906
47.

[Total hysterectomy in benign diseases of the uterus].

DE QUEIROZ AP, BOTO A, DA MAIA HS.

An Bras Ginecol. 1954 Jan;37(1):1-8. Undetermined Language. No abstract available.

PMID:
13148600

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