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Items: 1 to 50 of 134

1.

HIV status does not have an impact on positron emission tomography-computed tomography (PET-CT) findings or radiotherapy treatment recommendations in patients with locally advanced cervical cancer.

Simonds H, Botha MH, Ellmann A, Warwick J, Doruyter A, Neugut AI, Van Der Merwe H, Jacobson JS.

Int J Gynecol Cancer. 2019 Aug 13. pii: ijgc-2019-000641. doi: 10.1136/ijgc-2019-000641. [Epub ahead of print]

PMID:
31413068
2.

Nutrition and allergic diseases in urban and rural communities from the South African Food Allergy cohort.

Botha M, Basera W, Facey-Thomas HE, Gaunt B, Genuneit J, Gray CL, Kiragu W, Ramjith J, Watkins A, Levin ME.

Pediatr Allergy Immunol. 2019 Aug;30(5):511-521. doi: 10.1111/pai.13058. Epub 2019 Jun 2.

PMID:
30945339
3.

Exploring the feasibility of using mobile phones to improve the management of clients with cervical cancer precursor lesions.

Moodley J, Constant D, Botha MH, van der Merwe FH, Edwards A, Momberg M.

BMC Womens Health. 2019 Jan 7;19(1):2. doi: 10.1186/s12905-018-0702-1.

4.

Effects of diet on the childhood gut microbiome and its implications for atopic dermatitis.

Mahdavinia M, Rasmussen HE, Botha M, Binh Tran TD, Van den Berg JP, Sodergren E, Davis E, Engen K, Gray C, Lunjani N, Hlela C, Preite NZ, Basera W, Hobane L, Watkins A, Engen P, Mankahla A, Gaunt B, Thomas F, Tobin MC, Landay A, Weinstock GM, Keshavarzian A, Levin ME.

J Allergy Clin Immunol. 2019 Apr;143(4):1636-1637.e5. doi: 10.1016/j.jaci.2018.11.034. Epub 2018 Dec 19. No abstract available.

PMID:
30578881
5.

Competence in performing emergency skills: How good do doctors really think they are?

Dufourq N, Nicole Goldstein L, Botha M.

Afr J Emerg Med. 2017 Dec;7(4):151-156. doi: 10.1016/j.afjem.2017.05.011. Epub 2017 Aug 9.

6.

'This place is not for children like her': disability, ambiguous belonging and the claiming of disadvantage in postapartheid South Africa.

Botha M, Watermeyer B.

Med Humanit. 2018 Nov 13. pii: medhum-2018-011560. doi: 10.1136/medhum-2018-011560. [Epub ahead of print]

PMID:
30425117
7.

Cancer in pregnancy.

Botha MH, Rajaram S, Karunaratne K.

Int J Gynaecol Obstet. 2018 Oct;143 Suppl 2:137-142. doi: 10.1002/ijgo.12621.

PMID:
30306590
8.

Five-year overall survival following chemoradiation among HIV-positive and HIV-negative patients with locally advanced cervical carcinoma in a South African cohort.

Simonds HM, Botha MH, Neugut AI, Van Der Merwe FH, Jacobson JS.

Gynecol Oncol. 2018 Nov;151(2):215-220. doi: 10.1016/j.ygyno.2018.08.038. Epub 2018 Sep 5.

PMID:
30194006
9.

Predictive values of alpha-gal IgE levels and alpha-gal IgE: Total IgE ratio and oral food challenge-proven meat allergy in a population with a high prevalence of reported red meat allergy.

Mabelane T, Basera W, Botha M, Thomas HF, Ramjith J, Levin ME.

Pediatr Allergy Immunol. 2018 Dec;29(8):841-849. doi: 10.1111/pai.12969. Epub 2018 Sep 28.

PMID:
30144162
10.

Rural and urban food allergy prevalence from the South African Food Allergy (SAFFA) study.

Botha M, Basera W, Facey-Thomas HE, Gaunt B, Gray CL, Ramjith J, Watkins A, Levin ME.

J Allergy Clin Immunol. 2019 Feb;143(2):662-668.e2. doi: 10.1016/j.jaci.2018.07.023. Epub 2018 Aug 7.

PMID:
30096388
11.

Vulvar cancer is not a disease of the elderly: Treatment and outcome at a tertiary referral centre in South Africa.

Butt JL, Botha MH.

S Afr Med J. 2017 Oct 31;107(11):1000-1004. doi: 10.7196/SAMJ.2017.v107i11.12497.

12.

Synthesis and Antibacterial Activity of Benzo[4,5]isothiazolo[2,3-a]pyrazine-6,6-dioxide Derivatives.

Bassin JP, Botha MJ, Garikipati R, Goyal M, Martin L, Shah A.

Molecules. 2017 Nov 4;22(11). pii: E1889. doi: 10.3390/molecules22111889.

13.

Atopic dermatitis and food sensitization in South African toddlers: Role of fiber and gut microbiota.

Mahdavinia M, Rasmussen HE, Engen P, Van den Berg JP, Davis E, Engen K, Green SJ, Naqib A, Botha M, Gray C, Lunjani N, Hlela C, Basera W, Hobane L, Watkins A, Tobin MC, Landay A, Keshavarzian A, Levin ME.

Ann Allergy Asthma Immunol. 2017 Jun;118(6):742-743.e3. doi: 10.1016/j.anai.2017.04.011. No abstract available.

PMID:
28583264
14.

Patterns of prevalent HPV and STI co-infections and associated factors among HIV-negative young Western Cape, South African women: the EVRI trial.

Menezes LJ, Pokharel U, Sudenga SL, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim van der Loeff MF, van der Laan LE, Kipping S, Taylor D, Giuliano AR.

Sex Transm Infect. 2018 Feb;94(1):55-61. doi: 10.1136/sextrans-2016-053046. Epub 2017 May 10.

15.

HPV SEROSTATUS PRE- AND POST-VACCINATION IN A RANDOMIZED PHASE II PREPAREDNESS TRIAL AMONG YOUNG WESTERN CAPE, SOUTH AFRICAN WOMEN: THE EVRI TRIAL.

Sudenga SL, Torres BN, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim Van der Loeff MF, Van der Laan LE, Kipping S, Taylor D, Giuliano AR.

Papillomavirus Res. 2017 Jun;3:50-56. doi: 10.1016/j.pvr.2017.02.001. Epub 2017 Feb 16.

16.

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

Paquet T, Le Manach C, Cabrera DG, Younis Y, Henrich PP, Abraham TS, Lee MCS, Basak R, Ghidelli-Disse S, Lafuente-Monasterio MJ, Bantscheff M, Ruecker A, Blagborough AM, Zakutansky SE, Zeeman AM, White KL, Shackleford DM, Mannila J, Morizzi J, Scheurer C, Angulo-Barturen I, Martínez MS, Ferrer S, Sanz LM, Gamo FJ, Reader J, Botha M, Dechering KJ, Sauerwein RW, Tungtaeng A, Vanachayangkul P, Lim CS, Burrows J, Witty MJ, Marsh KC, Bodenreider C, Rochford R, Solapure SM, Jiménez-Díaz MB, Wittlin S, Charman SA, Donini C, Campo B, Birkholtz LM, Hanson KK, Drewes G, Kocken CHM, Delves MJ, Leroy D, Fidock DA, Waterson D, Street LJ, Chibale K.

Sci Transl Med. 2017 Apr 26;9(387). pii: eaad9735. doi: 10.1126/scitranslmed.aad9735.

17.

Women's experiences with cervical cancer screening in a colposcopy referral clinic in Cape Town, South Africa: a qualitative analysis.

Momberg M, Botha MH, Van der Merwe FH, Moodley J.

BMJ Open. 2017 Feb 17;7(2):e013914. doi: 10.1136/bmjopen-2016-013914.

18.

Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.

Singh K, Okombo J, Brunschwig C, Ndubi F, Barnard L, Wilkinson C, Njogu PM, Njoroge M, Laing L, Machado M, Prudêncio M, Reader J, Botha M, Nondaba S, Birkholtz LM, Lauterbach S, Churchyard A, Coetzer TL, Burrows JN, Yeates C, Denti P, Wiesner L, Egan TJ, Wittlin S, Chibale K.

J Med Chem. 2017 Feb 23;60(4):1432-1448. doi: 10.1021/acs.jmedchem.6b01641. Epub 2017 Feb 7.

PMID:
28094524
19.

Final Results of the Randomized Phase II NorCap-CA223 Trial Comparing First-Line All-Oral Versus Taxane-Based Chemotherapy for HER2-Negative Metastatic Breast Cancer.

Cinieri S, Chan A, Altundag K, Vandebroek A, Tubiana-Mathieu N, Barnadas A, Dodyk P, Lazzarelli S, Botha M, Rauch D, Villanova G, Coskun U.

Clin Breast Cancer. 2017 Apr;17(2):91-99.e1. doi: 10.1016/j.clbc.2016.06.014. Epub 2016 Jun 25.

PMID:
27756583
20.

Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.

Le Manach C, Nchinda AT, Paquet T, Gonzàlez Cabrera D, Younis Y, Han Z, Bashyam S, Zabiulla M, Taylor D, Lawrence N, White KL, Charman SA, Waterson D, Witty MJ, Wittlin S, Botha ME, Nondaba SH, Reader J, Birkholtz LM, Jiménez-Díaz MB, Martínez MS, Ferrer S, Angulo-Barturen I, Meister S, Antonova-Koch Y, Winzeler EA, Street LJ, Chibale K.

J Med Chem. 2016 Nov 10;59(21):9890-9905. Epub 2016 Oct 26.

PMID:
27748596
21.

In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species.

Moyo P, Botha ME, Nondaba S, Niemand J, Maharaj VJ, Eloff JN, Louw AI, Birkholtz L.

J Ethnopharmacol. 2016 Jun 5;185:235-42. doi: 10.1016/j.jep.2016.03.036. Epub 2016 Mar 16.

PMID:
26994818
22.

School-based human papillomavirus vaccination: An opportunity to increase knowledge about cervical cancer and improve uptake of screening.

Dreyer G, van der Merwe FH, Botha MH, Snyman LC, Constant D, Visser C, Harvey J.

S Afr Med J. 2015 Nov;105(11):912-6. doi: 10.7196/SAMJ.2015.v105i11.9814.

PMID:
26632317
23.

A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.

Le Manach C, Paquet T, Brunschwig C, Njoroge M, Han Z, Gonzàlez Cabrera D, Bashyam S, Dhinakaran R, Taylor D, Reader J, Botha M, Churchyard A, Lauterbach S, Coetzer TL, Birkholtz LM, Meister S, Winzeler EA, Waterson D, Witty MJ, Wittlin S, Jiménez-Díaz MB, Santos Martínez M, Ferrer S, Angulo-Barturen I, Street LJ, Chibale K.

J Med Chem. 2015 Nov 12;58(21):8713-22. doi: 10.1021/acs.jmedchem.5b01605. Epub 2015 Nov 2.

PMID:
26502160
24.

Cervical HPV natural history among young Western Cape, South African women: The randomized control EVRI Trial.

Sudenga SL, Torres BN, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim Van der Loeff MF, Van der Laan LE, Kipping S, Taylor D, Giuliano AR.

J Infect. 2016 Jan;72(1):60-9. doi: 10.1016/j.jinf.2015.10.001. Epub 2015 Oct 19.

25.

Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance.

Leisching G, Loos B, Botha M, Engelbrecht AM.

J Transl Med. 2015 Oct 16;13:328. doi: 10.1186/s12967-015-0689-4.

26.

HPV vaccine: Can we afford to hesitate?

South African HPV Advisory Board, Richter KL, Dreyer G, Lindeque BG, Botha MH.

S Afr Med J. 2014 Aug;104(8):522-3. No abstract available.

PMID:
26307795
28.

The Vaccine and Cervical Cancer Screen (VACCS) project: Linking cervical cancer screening to HPV vaccination in the South-West District of Tshwane, Gauteng, South Africa.

Snyman LC, Dreyer G, Botha MH, van der Merwe FH, Becker PJ.

S Afr Med J. 2015 Jan 6;105(2):115-20. doi: 10.7196/samj.8418.

PMID:
26242529
29.

The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer.

Leisching GR, Loos B, Botha MH, Engelbrecht AM.

Toxicology. 2015 Sep 1;335:72-8. doi: 10.1016/j.tox.2015.07.010. Epub 2015 Jul 19.

PMID:
26201060
30.

The South African Food Sensitisation and Food Allergy population-based study of IgE-mediated food allergy: validity, safety, and acceptability.

Basera W, Botha M, Gray CL, Lunjani N, Watkins AS, Venter C, Allen KJ, Hlela C, Zar HJ, Levin ME.

Ann Allergy Asthma Immunol. 2015 Aug;115(2):113-9. doi: 10.1016/j.anai.2015.06.003. Epub 2015 Jun 20.

PMID:
26105048
31.
32.
33.

Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.

Reader J, Botha M, Theron A, Lauterbach SB, Rossouw C, Engelbrecht D, Wepener M, Smit A, Leroy D, Mancama D, Coetzer TL, Birkholtz LM.

Malar J. 2015 May 22;14:213. doi: 10.1186/s12936-015-0718-z.

34.

A nontoxic concentration of cisplatin induces autophagy in cervical cancer: selective cancer cell death with autophagy inhibition as an adjuvant treatment.

Leisching G, Loos B, Botha M, Engelbrecht AM.

Int J Gynecol Cancer. 2015 Mar;25(3):380-8. doi: 10.1097/IGC.0000000000000365.

PMID:
25695544
35.

A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.

Burger PB, Williams M, Sprenger J, Reeksting SB, Botha M, Müller IB, Joubert F, Birkholtz LM, Louw AI.

Malar J. 2015 Feb 5;14:54. doi: 10.1186/s12936-015-0572-z.

36.

High HIV, HPV, and STI prevalence among young Western Cape, South African women: EVRI HIV prevention preparedness trial.

Giuliano AR, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, van der Laan LE, Papenfuss M, Engelbrecht S, Schim van der Loeff MF, Sudenga SL, Torres BN, Kipping S, Taylor D.

J Acquir Immune Defic Syndr. 2015 Feb 1;68(2):227-35. doi: 10.1097/QAI.0000000000000425. Erratum in: J Acquir Immune Defic Syndr. 2015 Oct 1;70(2):e72.

37.

Combination antiretroviral therapy reduces the detection risk of cervical human papilloma virus infection in women living with HIV.

Zeier MD, Botha MH, Engelbrecht S, Machekano RN, Jacobs GB, Isaacs S, van Schalkwyk M, van der Merwe H, Mason D, Nachega JB.

AIDS. 2015 Jan 2;29(1):59-66. doi: 10.1097/QAD.0000000000000512.

PMID:
25387313
38.

Safewards: the empirical basis of the model and a critical appraisal.

Bowers L, Alexander J, Bilgin H, Botha M, Dack C, James K, Jarrett M, Jeffery D, Nijman H, Owiti JA, Papadopoulos C, Ross J, Wright S, Stewart D.

J Psychiatr Ment Health Nurs. 2014 May;21(4):354-64. doi: 10.1111/jpm.12085. Epub 2014 Jan 24.

39.

Adrenaline and amiodarone dosages in resuscitation: rectifying misinformation.

Botha M, Wells M, Dickerson R, Wallis L, Stander M; ARREST Special Interest Group of EMSSA.

S Afr Med J. 2013 Sep 3;103(10):713-4. doi: 10.7196/samj.7347. Review.

PMID:
24079618
40.

The impact of voluntary exercise on relative telomere length in a rat model of developmental stress.

Botha M, Grace L, Bugarith K, Russell VA, Kidd M, Seedat S, Hemmings SM.

BMC Res Notes. 2012 Dec 27;5:697. doi: 10.1186/1756-0500-5-697.

41.

Impact of timing of antiretroviral therapy initiation on survival of cervical squamous intraepithelial lesions: a cohort analysis from South Africa.

Zeier MD, Nachega JB, Van Der Merwe FH, Eshun-Wilson I, Van Schalkwyk M, La Grange M, Mason D, Louw M, Botha MH.

Int J STD AIDS. 2012 Dec;23(12):890-6. doi: 10.1258/ijsa.2012.012040.

PMID:
23258831
42.

Introducing human papillomavirus vaccines into the health system in South Africa.

Botha MH, Dochez C.

Vaccine. 2012 Sep 7;30 Suppl 3:C28-34. doi: 10.1016/j.vaccine.2012.03.032. Review.

PMID:
22939017
43.

Practical management of sudden cardiac arrest on the football field.

Kramer EB, Botha M, Drezner J, Abdelrahman Y, Dvorak J.

Br J Sports Med. 2012 Dec;46(16):1094-6. doi: 10.1136/bjsports-2012-091376. Epub 2012 Aug 3.

PMID:
22864010
44.

Neutron radiotherapy in South Africa: neutron radiotherapy: society comments.

Fourie S, Abratt R, Botha M, De Muellenaere R, Gouws L, Hart G, Jordaan A, Szpak W.

S Afr Med J. 2012 Mar 23;102(5):271. No abstract available.

PMID:
22554323
45.

Lactobacillus equigenerosi strain Le1 invades equine epithelial cells.

Botha M, Botes M, Loos B, Smith C, Dicks LM.

Appl Environ Microbiol. 2012 Jun;78(12):4248-55. doi: 10.1128/AEM.00552-12. Epub 2012 Apr 13.

46.

Progression and persistence of low-grade cervical squamous intraepithelial lesions in women living with human immunodeficiency virus.

Zeier MD, Botha MH, van der Merwe FH, Eshun-Wilson I, van Schalkwyk M, la Grange M, Mason D, Louw M, Nachega JB.

J Low Genit Tract Dis. 2012 Jul;16(3):243-50. doi: 10.1097/LGT.0b013e3182403d18.

PMID:
22460273
47.

Part V. Surveillance activities.

Bamford C, Brink A, Govender N, Lewis DA, Perovic O, Botha M, Harris B, Keddy KH, Gelband H, Duse AG.

S Afr Med J. 2011 Jul 28;101(8 Pt 2):579-82. No abstract available.

PMID:
21920136
48.

Part IV. Human infections and antibiotic resistance.

Crowther-Gibson P, Govender N, Lewis DA, Bamford C, Brink A, von Gottberg A, Klugman K, du Plessis M, Fali A, Harris B, Keddy K, Botha M.

S Afr Med J. 2011 Jul 28;101(8 Pt 2):567-78. No abstract available.

PMID:
21920135
49.

Position statement. Pre-hospital rapid sequence intubation.

Stein C, Botha M, Kramer E, Nevin D, Dickerson R, Goldstein L, Wells M, Muhlbauer D, Vincent-Lambert C; Emergency Medicine Society of South Africa (EMSSA) and the Resuscitation Council of Southern Africa.

S Afr Med J. 2011 Mar 1;101(3):163. No abstract available.

PMID:
21382243
50.

Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock.

Botha M, Chiang AN, Needham PG, Stephens LL, Hoppe HC, Külzer S, Przyborski JM, Lingelbach K, Wipf P, Brodsky JL, Shonhai A, Blatch GL.

Cell Stress Chaperones. 2011 Jul;16(4):389-401. doi: 10.1007/s12192-010-0250-6. Epub 2010 Dec 30.

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