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Items: 34

1.

The Effects of Sindbis Viral Vectors on Neuronal Function.

Uyaniker S, van der Spek SJF, Reinders NR, Xiong H, Li KW, Bossers K, Smit AB, Verhaagen J, Kessels HW.

Front Cell Neurosci. 2019 Aug 8;13:362. doi: 10.3389/fncel.2019.00362. eCollection 2019.

2.

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis.

Melief J, Orre M, Bossers K, van Eden CG, Schuurman KG, Mason MRJ, Verhaagen J, Hamann J, Huitinga I.

Acta Neuropathol Commun. 2019 Apr 25;7(1):60. doi: 10.1186/s40478-019-0705-7.

3.

Capturing the Genesis of an Active Fischer-Tropsch Synthesis Catalyst with Operando X-ray Nanospectroscopy.

van Ravenhorst IK, Vogt C, Oosterbeek H, Bossers KW, Moya-Cancino JG, van Bavel AP, van der Eerden AMJ, Vine D, de Groot FMF, Meirer F, Weckhuysen BM.

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):11957-11962. doi: 10.1002/anie.201806354. Epub 2018 Aug 17.

PMID:
30070756
4.

Genesis of MgCl2 -based Ziegler-Natta Catalysts as Probed with Operando Spectroscopy.

Piovano A, Pletcher P, Velthoen MEZ, Zanoni S, Chung SH, Bossers K, Jongkind MK, Fiore G, Groppo E, Weckhuysen BM.

Chemphyschem. 2018 Oct 19;19(20):2662-2671. doi: 10.1002/cphc.201800592. Epub 2018 Aug 3.

PMID:
30051629
5.

Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions.

Hendrickx DAE, van Scheppingen J, van der Poel M, Bossers K, Schuurman KG, van Eden CG, Hol EM, Hamann J, Huitinga I.

Front Immunol. 2017 Dec 21;8:1810. doi: 10.3389/fimmu.2017.01810. eCollection 2017.

6.

Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.

Korecka JA, Moloney EB, Eggers R, Hobo B, Scheffer S, Ras-Verloop N, Pasterkamp RJ, Swaab DF, Smit AB, van Kesteren RE, Bossers K, Verhaagen J.

J Neurosci. 2017 Sep 27;37(39):9361-9379. doi: 10.1523/JNEUROSCI.0084-17.2017. Epub 2017 Aug 21.

7.

MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer's disease.

Zhu QB, Unmehopa U, Bossers K, Hu YT, Verwer R, Balesar R, Zhao J, Bao AM, Swaab D.

Brain. 2016 Mar;139(Pt 3):908-21. doi: 10.1093/brain/awv383. Epub 2016 Jan 20.

PMID:
26792551
8.

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

Bennis A, Gorgels TG, Ten Brink JB, van der Spek PJ, Bossers K, Heine VM, Bergen AA.

PLoS One. 2015 Oct 30;10(10):e0141597. doi: 10.1371/journal.pone.0141597. eCollection 2015.

9.

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.

Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A.

Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492.

PMID:
26468326
10.

Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes.

Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE, Shaw PJ, Kirby J, Veldink JH, Macklis JD, Powell JF, Al-Chalabi A.

Neurobiol Aging. 2015 May;36(5):2006.e1-9. doi: 10.1016/j.neurobiolaging.2015.02.017. Epub 2015 Feb 19.

PMID:
25801576
11.

Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.

Marquer C, Laine J, Dauphinot L, Hanbouch L, Lemercier-Neuillet C, Pierrot N, Bossers K, Le M, Corlier F, Benstaali C, Saudou F, Thinakaran G, Cartier N, Octave JN, Duyckaerts C, Potier MC.

Mol Neurodegener. 2014 Dec 18;9:60. doi: 10.1186/1750-1326-9-60.

12.

Storm before the quiet: neuronal hyperactivity and Aβ in the presymptomatic stages of Alzheimer's disease.

Stargardt A, Swaab DF, Bossers K.

Neurobiol Aging. 2015 Jan;36(1):1-11. doi: 10.1016/j.neurobiolaging.2014.08.014. Epub 2014 Sep 28.

PMID:
25444609
13.

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.

Orre M, Kamphuis W, Osborn LM, Jansen AHP, Kooijman L, Bossers K, Hol EM.

Neurobiol Aging. 2014 Dec;35(12):2746-2760. doi: 10.1016/j.neurobiolaging.2014.06.004. Epub 2014 Jun 14.

PMID:
25002035
14.

Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.

Alves CH, Bossers K, Vos RM, Essing AH, Swagemakers S, van der Spek PJ, Verhaagen J, Wijnholds J.

PLoS One. 2013 Dec 6;8(12):e82532. doi: 10.1371/journal.pone.0082532. eCollection 2013.

15.

Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease.

Sala Frigerio C, Lau P, Salta E, Tournoy J, Bossers K, Vandenberghe R, Wallin A, Bjerke M, Zetterberg H, Blennow K, De Strooper B.

Neurology. 2013 Dec 10;81(24):2103-6. doi: 10.1212/01.wnl.0000437306.37850.22. Epub 2013 Nov 8.

PMID:
24212398
16.

Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase?

Wirz KT, Keitel S, Swaab DF, Verhaagen J, Bossers K.

J Alzheimers Dis. 2014;38(4):719-40. doi: 10.3233/JAD-130920. Review.

PMID:
24072070
17.

Alteration of the microRNA network during the progression of Alzheimer's disease.

Lau P, Bossers K, Janky R, Salta E, Frigerio CS, Barbash S, Rothman R, Sierksma AS, Thathiah A, Greenberg D, Papadopoulou AS, Achsel T, Ayoubi T, Soreq H, Verhaagen J, Swaab DF, Aerts S, De Strooper B.

EMBO Mol Med. 2013 Oct;5(10):1613-34. doi: 10.1002/emmm.201201974. Epub 2013 Sep 9.

18.

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice.

Orre M, Kamphuis W, Osborn LM, Melief J, Kooijman L, Huitinga I, Klooster J, Bossers K, Hol EM.

Neurobiol Aging. 2014 Jan;35(1):1-14. doi: 10.1016/j.neurobiolaging.2013.07.008. Epub 2013 Aug 15.

PMID:
23954174
19.

Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling.

Korecka JA, van Kesteren RE, Blaas E, Spitzer SO, Kamstra JH, Smit AB, Swaab DF, Verhaagen J, Bossers K.

PLoS One. 2013 May 28;8(5):e63862. doi: 10.1371/journal.pone.0063862. Print 2013.

20.

Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment.

Korecka JA, Eggers R, Swaab DF, Bossers K, Verhaagen J.

Restor Neurol Neurosci. 2013;31(2):155-67. doi: 10.3233/RNN-110222.

PMID:
23271419
21.

Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model.

Wirz KT, Bossers K, Stargardt A, Kamphuis W, Swaab DF, Hol EM, Verhaagen J.

Neurobiol Aging. 2013 May;34(5):1328-42. doi: 10.1016/j.neurobiolaging.2012.11.008. Epub 2012 Dec 12.

22.

β-arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology.

Liu X, Zhao X, Zeng X, Bossers K, Swaab DF, Zhao J, Pei G.

Cell Res. 2013 Mar;23(3):351-65. doi: 10.1038/cr.2012.167. Epub 2012 Dec 4.

23.

Molecular target discovery for neural repair in the functional genomics era.

Verhaagen J, Van Kesteren RE, Bossers KA, Macgillavry HD, Mason MR, Smit AB.

Handb Clin Neurol. 2012;109:595-616. doi: 10.1016/B978-0-444-52137-8.00037-1. Review.

PMID:
23098739
24.

Gene expression and functional annotation of the human ciliary body epithelia.

Janssen SF, Gorgels TG, Bossers K, Ten Brink JB, Essing AH, Nagtegaal M, van der Spek PJ, Jansonius NM, Bergen AA.

PLoS One. 2012;7(9):e44973. doi: 10.1371/journal.pone.0044973. Epub 2012 Sep 18.

25.

A novel peptidomics approach to detect markers of Alzheimer's disease in cerebrospinal fluid.

Wijte D, McDonnell LA, Balog CI, Bossers K, Deelder AM, Swaab DF, Verhaagen J, Mayboroda OA.

Methods. 2012 Apr;56(4):500-7. doi: 10.1016/j.ymeth.2012.03.018. Epub 2012 Mar 24.

PMID:
22465281
26.

Alterations in the histaminergic system in Alzheimer's disease: a postmortem study.

Shan L, Bossers K, Unmehopa U, Bao AM, Swaab DF.

Neurobiol Aging. 2012 Nov;33(11):2585-98. doi: 10.1016/j.neurobiolaging.2011.12.026. Epub 2012 Jan 26.

PMID:
22284987
27.

Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.

Shan L, Bossers K, Luchetti S, Balesar R, Lethbridge N, Chazot PL, Bao AM, Swaab DF.

Neurobiol Aging. 2012 Jul;33(7):1488.e1-13. doi: 10.1016/j.neurobiolaging.2011.10.016. Epub 2011 Nov 26.

PMID:
22118942
28.

Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair.

Nandoe Tewarie RD, Bossers K, Ritfeld GJ, Blits B, Grotenhuis JA, Verhaagen J, Oudega M.

Restor Neurol Neurosci. 2011;29(3):187-201. doi: 10.3233/RNN-2011-0591.

PMID:
21586825
29.

A meta-analysis of microarray-based gene expression studies of olfactory bulb-derived olfactory ensheathing cells.

Roet KC, Bossers K, Franssen EH, Ruitenberg MJ, Verhaagen J.

Exp Neurol. 2011 May;229(1):10-45. doi: 10.1016/j.expneurol.2011.03.001. Epub 2011 Mar 23. Review.

PMID:
21396936
30.

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease.

Bossers K, Wirz KT, Meerhoff GF, Essing AH, van Dongen JW, Houba P, Kruse CG, Verhaagen J, Swaab DF.

Brain. 2010 Dec;133(Pt 12):3699-723. doi: 10.1093/brain/awq258. Epub 2010 Oct 1.

PMID:
20889584
31.

Neurosteroid biosynthetic pathway changes in substantia nigra and caudate nucleus in Parkinson's disease.

Luchetti S, Bossers K, Frajese GV, Swaab DF.

Brain Pathol. 2010 Sep;20(5):945-51. doi: 10.1111/j.1750-3639.2010.00396.x. Epub 2010 Mar 19.

PMID:
20406233
32.

Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility.

Bossers K, Ylstra B, Brakenhoff RH, Smeets SJ, Verhaagen J, van de Wiel MA.

BMC Genomics. 2010 Feb 17;11:112. doi: 10.1186/1471-2164-11-112.

33.

Neurosteroid biosynthetic pathways changes in prefrontal cortex in Alzheimer's disease.

Luchetti S, Bossers K, Van de Bilt S, Agrapart V, Morales RR, Frajese GV, Swaab DF.

Neurobiol Aging. 2011 Nov;32(11):1964-76. doi: 10.1016/j.neurobiolaging.2009.12.014. Epub 2009 Dec 31.

PMID:
20045216
34.

Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death.

Bossers K, Meerhoff G, Balesar R, van Dongen JW, Kruse CG, Swaab DF, Verhaagen J.

Brain Pathol. 2009 Jan;19(1):91-107. doi: 10.1111/j.1750-3639.2008.00171.x. Epub 2008 May 7.

PMID:
18462474

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