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Items: 40


Immunogenicity and performance of an enterovirus 71 virus-like-particle vaccine in nonhuman primates.

Lim PY, Hickey AC, Jamiluddin MF, Hamid S, Kramer J, Santos R, Bossart KN, Cardosa MJ.

Vaccine. 2015 Nov 4;33(44):6017-24. doi: 10.1016/j.vaccine.2015.05.108. Epub 2015 Aug 11.


Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody.

Geisbert TW, Mire CE, Geisbert JB, Chan YP, Agans KN, Feldmann F, Fenton KA, Zhu Z, Dimitrov DS, Scott DP, Bossart KN, Feldmann H, Broder CC.

Sci Transl Med. 2014 Jun 25;6(242):242ra82. doi: 10.1126/scitranslmed.3008929.


A recombinant Hendra virus G glycoprotein subunit vaccine protects nonhuman primates against Hendra virus challenge.

Mire CE, Geisbert JB, Agans KN, Feng YR, Fenton KA, Bossart KN, Yan L, Chan YP, Broder CC, Geisbert TW.

J Virol. 2014 May;88(9):4624-31. doi: 10.1128/JVI.00005-14. Epub 2014 Feb 12.


Serotype-specific host responses in rhesus macaques after primary dengue challenge.

Hickey AC, Koster JA, Thalmann CM, Hardcastle K, Tio PH, Cardosa MJ, Bossart KN.

Am J Trop Med Hyg. 2013 Dec;89(6):1043-57. doi: 10.4269/ajtmh.13-0145. Epub 2013 Sep 23.


Paramyxovirus entry.

Bossart KN, Fusco DL, Broder CC.

Adv Exp Med Biol. 2013;790:95-127. doi: 10.1007/978-1-4614-7651-1_6. Review.


Host cell tropism mediated by Australian bat lyssavirus envelope glycoproteins.

Weir DL, Smith IL, Bossart KN, Wang LF, Broder CC.

Virology. 2013 Sep;444(1-2):21-30. doi: 10.1016/j.virol.2013.06.016. Epub 2013 Jul 10.


A treatment for and vaccine against the deadly Hendra and Nipah viruses.

Broder CC, Xu K, Nikolov DB, Zhu Z, Dimitrov DS, Middleton D, Pallister J, Geisbert TW, Bossart KN, Wang LF.

Antiviral Res. 2013 Oct;100(1):8-13. doi: 10.1016/j.antiviral.2013.06.012. Epub 2013 Jul 6. Review.


The distribution of henipaviruses in Southeast Asia and Australasia: is Wallace's line a barrier to Nipah virus?

Breed AC, Meers J, Sendow I, Bossart KN, Barr JA, Smith I, Wacharapluesadee S, Wang L, Field HE.

PLoS One. 2013 Apr 24;8(4):e61316. doi: 10.1371/journal.pone.0061316. Print 2013.


A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge.

Bossart KN, Rockx B, Feldmann F, Brining D, Scott D, LaCasse R, Geisbert JB, Feng YR, Chan YP, Hickey AC, Broder CC, Feldmann H, Geisbert TW.

Sci Transl Med. 2012 Aug 8;4(146):146ra107. doi: 10.1126/scitranslmed.3004241.


Immunization strategies against henipaviruses.

Broder CC, Geisbert TW, Xu K, Nikolov DB, Wang LF, Middleton D, Pallister J, Bossart KN.

Curr Top Microbiol Immunol. 2012;359:197-223. doi: 10.1007/82_2012_213. Review.


Site occupancy and glycan compositional analysis of two soluble recombinant forms of the attachment glycoprotein of Hendra virus.

Colgrave ML, Snelling HJ, Shiell BJ, Feng YR, Chan YP, Bossart KN, Xu K, Nikolov DB, Broder CC, Michalski WP.

Glycobiology. 2012 Apr;22(4):572-84. doi: 10.1093/glycob/cwr180. Epub 2011 Dec 14.


A neutralizing human monoclonal antibody protects african green monkeys from hendra virus challenge.

Bossart KN, Geisbert TW, Feldmann H, Zhu Z, Feldmann F, Geisbert JB, Yan L, Feng YR, Brining D, Scott D, Wang Y, Dimitrov AS, Callison J, Chan YP, Hickey AC, Dimitrov DS, Broder CC, Rockx B.

Sci Transl Med. 2011 Oct 19;3(105):105ra103. doi: 10.1126/scitranslmed.3002901.


A novel model of lethal Hendra virus infection in African green monkeys and the effectiveness of ribavirin treatment.

Rockx B, Bossart KN, Feldmann F, Geisbert JB, Hickey AC, Brining D, Callison J, Safronetz D, Marzi A, Kercher L, Long D, Broder CC, Feldmann H, Geisbert TW.

J Virol. 2010 Oct;84(19):9831-9. doi: 10.1128/JVI.01163-10. Epub 2010 Jul 21.


Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.

Geisbert TW, Daddario-DiCaprio KM, Hickey AC, Smith MA, Chan YP, Wang LF, Mattapallil JJ, Geisbert JB, Bossart KN, Broder CC.

PLoS One. 2010 May 18;5(5):e10690. doi: 10.1371/journal.pone.0010690.


A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection.

Bossart KN, Zhu Z, Middleton D, Klippel J, Crameri G, Bingham J, McEachern JA, Green D, Hancock TJ, Chan YP, Hickey AC, Dimitrov DS, Wang LF, Broder CC.

PLoS Pathog. 2009 Oct;5(10):e1000642. doi: 10.1371/journal.ppat.1000642. Epub 2009 Oct 30.


A glycosylated peptide in the West Nile virus envelope protein is immunogenic during equine infection.

Hobson-Peters J, Toye P, Sánchez MD, Bossart KN, Wang LF, Clark DC, Cheah WY, Hall RA.

J Gen Virol. 2008 Dec;89(Pt 12):3063-72. doi: 10.1099/vir.0.2008/003731-0.


Residues in the stalk domain of the hendra virus g glycoprotein modulate conformational changes associated with receptor binding.

Bishop KA, Hickey AC, Khetawat D, Patch JR, Bossart KN, Zhu Z, Wang LF, Dimitrov DS, Broder CC.

J Virol. 2008 Nov;82(22):11398-409. doi: 10.1128/JVI.02654-07. Epub 2008 Sep 17.


A recombinant subunit vaccine formulation protects against lethal Nipah virus challenge in cats.

McEachern JA, Bingham J, Crameri G, Green DJ, Hancock TJ, Middleton D, Feng YR, Broder CC, Wang LF, Bossart KN.

Vaccine. 2008 Jul 23;26(31):3842-52. doi: 10.1016/j.vaccine.2008.05.016. Epub 2008 Jun 2.


Expression of novel genes encoded by the paramyxovirus J virus.

Jack PJ, Anderson DE, Bossart KN, Marsh GA, Yu M, Wang LF.

J Gen Virol. 2008 Jun;89(Pt 6):1434-41. doi: 10.1099/vir.0.83638-0.


Serotype-independent detection of foot-and-mouth disease virus.

Muller JD, McEachern JA, Bossart KN, Hansson E, Yu M, Clavijo A, Hammond JM, Wang LF.

J Virol Methods. 2008 Jul;151(1):146-53. doi: 10.1016/j.jviromet.2008.03.011. Epub 2008 Apr 25.


Exceptionally potent cross-reactive neutralization of Nipah and Hendra viruses by a human monoclonal antibody.

Zhu Z, Bossart KN, Bishop KA, Crameri G, Dimitrov AS, McEachern JA, Feng Y, Middleton D, Wang LF, Broder CC, Dimitrov DS.

J Infect Dis. 2008 Mar 15;197(6):846-53. doi: 10.1086/528801.


Functional studies of host-specific ephrin-B ligands as Henipavirus receptors.

Bossart KN, Tachedjian M, McEachern JA, Crameri G, Zhu Z, Dimitrov DS, Broder CC, Wang LF.

Virology. 2008 Mar 15;372(2):357-71. Epub 2007 Dec 4.


Identification of Hendra virus G glycoprotein residues that are critical for receptor binding.

Bishop KA, Stantchev TS, Hickey AC, Khetawat D, Bossart KN, Krasnoperov V, Gill P, Feng YR, Wang L, Eaton BT, Wang LF, Broder CC.

J Virol. 2007 Jun;81(11):5893-901. Epub 2007 Mar 21.


Neutralization assays for differential henipavirus serology using Bio-Plex protein array systems.

Bossart KN, McEachern JA, Hickey AC, Choudhry V, Dimitrov DS, Eaton BT, Wang LF.

J Virol Methods. 2007 Jun;142(1-2):29-40. Epub 2007 Feb 9.


Targeted strategies for henipavirus therapeutics.

Bossart KN, Bingham J, Middleton D.

Open Virol J. 2007;1:14-25. doi: 10.2174/1874357900701010014. Epub 2007 Sep 28.


Feline model of acute nipah virus infection and protection with a soluble glycoprotein-based subunit vaccine.

Mungall BA, Middleton D, Crameri G, Bingham J, Halpin K, Russell G, Green D, McEachern J, Pritchard LI, Eaton BT, Wang LF, Bossart KN, Broder CC.

J Virol. 2006 Dec;80(24):12293-302. Epub 2006 Sep 27.


Developments towards effective treatments for Nipah and Hendra virus infection.

Bossart KN, Broder CC.

Expert Rev Anti Infect Ther. 2006 Feb;4(1):43-55. Review.


Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies.

Zhu Z, Dimitrov AS, Bossart KN, Crameri G, Bishop KA, Choudhry V, Mungall BA, Feng YR, Choudhary A, Zhang MY, Feng Y, Wang LF, Xiao X, Eaton BT, Broder CC, Dimitrov DS.

J Virol. 2006 Jan;80(2):891-9.


Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein.

Bossart KN, Mungall BA, Crameri G, Wang LF, Eaton BT, Broder CC.

Virol J. 2005 Jul 18;2:57.


Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus.

Bonaparte MI, Dimitrov AS, Bossart KN, Crameri G, Mungall BA, Bishop KA, Choudhry V, Dimitrov DS, Wang LF, Eaton BT, Broder CC.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10652-7. Epub 2005 Jul 5.


Receptor binding, fusion inhibition, and induction of cross-reactive neutralizing antibodies by a soluble G glycoprotein of Hendra virus.

Bossart KN, Crameri G, Dimitrov AS, Mungall BA, Feng YR, Patch JR, Choudhary A, Wang LF, Eaton BT, Broder CC.

J Virol. 2005 Jun;79(11):6690-702.


Henipaviruses: recent observations on regulation of transcription and the nature of the cell receptor.

Eaton BT, Wright PJ, Wang LF, Sergeyev O, Michalski WP, Bossart KN, Broder CC.

Arch Virol Suppl. 2004;(18):122-31. Review.


Viral glycoprotein-mediated cell fusion assays using vaccinia virus vectors.

Bossart KN, Broder CC.

Methods Mol Biol. 2004;269:309-32. Review.


Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteins.

Bossart KN, Wang LF, Flora MN, Chua KB, Lam SK, Eaton BT, Broder CC.

J Virol. 2002 Nov;76(22):11186-98.


Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus.

Bossart KN, Wang LF, Eaton BT, Broder CC.

Virology. 2001 Nov 10;290(1):121-35.


The role of CD80 and CD86 in enhancing CD8(+) cell suppression of HIV replication.

Barker E, Bossart KN, Fujimura SH, Levy JA.

Cell Immunol. 1999 Sep 15;196(2):95-103.


Differential effects of CD28 costimulation on HIV production by CD4+ cells.

Barker E, Bossart KN, Levy JA.

J Immunol. 1998 Dec 1;161(11):6223-7.


CD28 costimulation increases CD8+ cell suppression of HIV replication.

Barker E, Bossart KN, Fujimura SH, Levy JA.

J Immunol. 1997 Nov 15;159(10):5123-31.


CD8+ cells from asymptomatic human immunodeficiency virus-infected individuals suppress superinfection of their peripheral blood mononuclear cells.

Barker E, Bossart KN, Locher CP, Patterson BK, Levy JA.

J Gen Virol. 1996 Dec;77 ( Pt 12):2953-62.


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