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Items: 1 to 50 of 52

1.

Safety, Feasibility, and Efficiency of a New Cooling Device Using Intravenous Cold Infusions for Fever Control.

Willms JF, Boss O, Keller E.

Neurocrit Care. 2019 Feb;30(1):149-156. doi: 10.1007/s12028-018-0588-7.

PMID:
30097980
2.

Cerebral venous thrombosis requiring invasive treatment for elevated intracranial pressure in women with combined hormonal contraceptive intake: risk factors, anatomical distribution, and clinical presentation.

Roethlisberger M, Gut L, Zumofen DW, Fisch U, Boss O, Maldaner N, Croci DM, Taub E, Corti N, Burkhardt JK, Guzman R, Bozinov O, Mariani L.

Neurosurg Focus. 2018 Jul;45(1):E12. doi: 10.3171/2018.4.FOCUS1891.

PMID:
29961388
3.

Decision tree analysis in subarachnoid hemorrhage: prediction of outcome parameters during the course of aneurysmal subarachnoid hemorrhage using decision tree analysis.

Hostettler IC, Muroi C, Richter JK, Schmid J, Neidert MC, Seule M, Boss O, Pangalu A, Germans MR, Keller E.

J Neurosurg. 2018 Dec 1;129(6):1499-1510. doi: 10.3171/2017.7.JNS17677.

PMID:
29350603
4.

Temperature variability in the day-night cycle is associated with further intracranial pressure during therapeutic hypothermia.

Nogueira AB, Annen E, Boss O, Farokhzad F, Sikorski C, Keller E.

J Transl Med. 2017 Aug 3;15(1):170. doi: 10.1186/s12967-017-1272-y.

5.

Lumbar total disc replacement: correlation of clinical outcome and radiological parameters.

Boss OL, Tomasi SO, Bäurle B, Sgier F, Hausmann ON.

Acta Neurochir (Wien). 2013 Oct;155(10):1923-30. doi: 10.1007/s00701-013-1774-1. Epub 2013 Jun 8.

PMID:
23748926
6.

Recruitment of brown adipose tissue as a therapy for obesity-associated diseases.

Boss O, Farmer SR.

Front Endocrinol (Lausanne). 2012 Feb 6;3:14. doi: 10.3389/fendo.2012.00014. eCollection 2012.

7.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM.

Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.

8.

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.

Smith JJ, Kenney RD, Gagne DJ, Frushour BP, Ladd W, Galonek HL, Israelian K, Song J, Razvadauskaite G, Lynch AV, Carney DP, Johnson RJ, Lavu S, Iffland A, Elliott PJ, Lambert PD, Elliston KO, Jirousek MR, Milne JC, Boss O.

BMC Syst Biol. 2009 Mar 10;3:31. doi: 10.1186/1752-0509-3-31.

9.

Sirtuins--novel therapeutic targets to treat age-associated diseases.

Lavu S, Boss O, Elliott PJ, Lambert PD.

Nat Rev Drug Discov. 2008 Oct;7(10):841-53. doi: 10.1038/nrd2665. Review. Erratum in: Nat Rev Drug Discov. 2009 Jun;8(6):516.

PMID:
18827827
10.

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH.

Nature. 2007 Nov 29;450(7170):712-6.

11.

Targeting PGC-1 alpha to control energy homeostasis.

Wu Z, Boss O.

Expert Opin Ther Targets. 2007 Oct;11(10):1329-38. Review.

PMID:
17907962
12.

Resveratrol improves health and survival of mice on a high-calorie diet.

Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA.

Nature. 2006 Nov 16;444(7117):337-42. Epub 2006 Nov 1.

13.

The obesity epidemic: current and future pharmacological treatments.

Hofbauer KG, Nicholson JR, Boss O.

Annu Rev Pharmacol Toxicol. 2007;47:565-92. Review.

PMID:
17002599
14.

Serotonin reciprocally regulates melanocortin neurons to modulate food intake.

Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, Mountjoy KG, Clifton PG, Lowell BB, Friedman JM, Horvath T, Butler AA, Elmquist JK, Cowley MA.

Neuron. 2006 Jul 20;51(2):239-49.

15.

A role for skeletal muscle stearoyl-CoA desaturase 1 in control of thermogenesis.

Mainieri D, Summermatter S, Seydoux J, Montani JP, Rusconi S, Russell AP, Boss O, Buchala AJ, Dulloo AG.

FASEB J. 2006 Aug;20(10):1751-3. Epub 2006 Jun 29.

PMID:
16809433
16.

beta-Adrenergic control of stearoyl-CoA desaturase 1 repression in relation to sympathoadrenal regulation of thermogenesis.

Mainieri D, Montani JP, Seydoux J, Giacobino JP, Boss O, Dulloo AG.

Int J Obes (Lond). 2007 Feb;31(2):378-81. Epub 2006 Jun 27.

PMID:
16801925
17.

Adipose targets for obesity drug development.

Boss O, Bergenhem N.

Expert Opin Ther Targets. 2006 Feb;10(1):119-34. Review.

PMID:
16441232
18.

Divergence of melanocortin pathways in the control of food intake and energy expenditure.

Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB.

Cell. 2005 Nov 4;123(3):493-505.

19.

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB.

J Clin Invest. 2004 Dec;114(11):1666-75.

20.

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.

Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM.

Nature. 2002 Aug 15;418(6899):797-801.

PMID:
12181572
21.

Leptin directly stimulates thermogenesis in skeletal muscle.

Dulloo AG, Stock MJ, Solinas G, Boss O, Montani JP, Seydoux J.

FEBS Lett. 2002 Mar 27;515(1-3):109-13.

22.

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB.

Cell. 2001 Jun 15;105(6):745-55.

23.

Effects of estrous cycle and steroid replacement on the expression of leptin and uncoupling proteins in adipose tissue in the rat.

Luukkaa V, Savontaus E, Rouru J, Virtanen KA, Boss O, Huhtaniemi I, Koulu M, Pesonen U, Huupponen R.

Gynecol Endocrinol. 2001 Apr;15(2):103-12.

PMID:
11379006
24.

Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance.

Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB, Neel BG.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5187-92. Epub 2001 Apr 17.

25.

Cloning and functional characterization of an uncoupling protein homolog in hummingbirds.

Vianna CR, Hagen T, Zhang CY, Bachman E, Boss O, Gereben B, Moriscot AS, Lowell BB, Bicudo JE, Bianco AC.

Physiol Genomics. 2001 Apr 2;5(3):137-45.

PMID:
11285367
26.

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver.

Abel ED, Peroni O, Kim JK, Kim YB, Boss O, Hadro E, Minnemann T, Shulman GI, Kahn BB.

Nature. 2001 Feb 8;409(6821):729-33.

PMID:
11217863
27.

Linkage exclusion analysis of the chromosome 11 region containing UCP2 and UCP3 with obesity-related phenotypes in Mexican Americans.

Comuzzie AG, Almasy L, Cole SA, Boss O, Giacobino JP, Muzzin P, Stern MP, MacCluer JW, Blangero J, Hixson JE.

Int J Obes Relat Metab Disord. 2000 Aug;24(8):1065-8.

PMID:
10951548
28.

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.

Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB.

Mol Cell Biol. 2000 Aug;20(15):5479-89.

29.

Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.

Boss O, Hagen T, Lowell BB.

Diabetes. 2000 Feb;49(2):143-56. Review.

PMID:
10868929
30.

Physiological relationships of uncoupling protein-2 gene expression in human adipose tissue in vivo.

Pinkney JH, Boss O, Bray GA, Bulmer K, Coppack SW, Mohamed-Ali V.

J Clin Endocrinol Metab. 2000 Jun;85(6):2312-7.

PMID:
10852469
31.

Synthesis and evaluation of aminocyclopentitol inhibitors of beta-glucosidases.

Boss O, Leroy E, Blaser A, Reymond JL.

Org Lett. 2000 Jan 27;2(2):151-4.

PMID:
10814269
32.

Energy metabolism in uncoupling protein 3 gene knockout mice.

Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB.

J Biol Chem. 2000 May 26;275(21):16258-66.

33.

Uncoupling protein 3: its possible biological role and mode of regulation in rodents and humans.

Muzzin P, Boss O, Giacobino JP.

J Bioenerg Biomembr. 1999 Oct;31(5):467-73. Review.

PMID:
10653475
34.

Expression of peroxisome proliferator-activated receptors in lean and obese Zucker rats.

Gorla-Bajszczak A, Siegrist-Kaiser C, Boss O, Burger AG, Meier CA.

Eur J Endocrinol. 2000 Jan;142(1):71-8.

PMID:
10633225
35.
36.

Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat.

Zakrzewska KE, Cusin I, Stricker-Krongrad A, Boss O, Ricquier D, Jeanrenaud B, Rohner-Jeanrenaud F.

Diabetes. 1999 Feb;48(2):365-70.

PMID:
10334315
37.

Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle.

Lanni A, Beneduce L, Lombardi A, Moreno M, Boss O, Muzzin P, Giacobino JP, Goglia F.

FEBS Lett. 1999 Feb 12;444(2-3):250-4.

38.

The uncoupling proteins, a review.

Boss O, Muzzin P, Giacobino JP.

Eur J Endocrinol. 1998 Jul;139(1):1-9. Review. No abstract available.

PMID:
9703368
39.

Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity.

Boss O, Bobbioni-Harsch E, Assimacopoulos-Jeannet F, Muzzin P, Munger R, Giacobino JP, Golay A.

Lancet. 1998 Jun 27;351(9120):1933. No abstract available.

PMID:
9654269
40.

Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins.

Cusin I, Zakrzewska KE, Boss O, Muzzin P, Giacobino JP, Ricquier D, Jeanrenaud B, Rohner-Jeanrenaud F.

Diabetes. 1998 Jul;47(7):1014-9.

PMID:
9648822
41.

Differential regulation of uncoupling proteins by chronic treatments with beta 3-adrenergic agonist BRL 35135 and metformin in obese fa/fa Zucker rats.

Savontaus E, Rouru J, Boss O, Huupponen R, Koulu M.

Biochem Biophys Res Commun. 1998 May 29;246(3):899-904.

PMID:
9618309
42.

Genomic structure of uncoupling protein-3 (UCP3) and its assignment to chromosome 11q13.

Boss O, Giacobino JP, Muzzin P.

Genomics. 1998 Feb 1;47(3):425-6. No abstract available.

PMID:
9480760
43.

Effect of endurance training on mRNA expression of uncoupling proteins 1, 2, and 3 in the rat.

Boss O, Samec S, Desplanches D, Mayet MH, Seydoux J, Muzzin P, Giacobino JP.

FASEB J. 1998 Mar;12(3):335-9.

PMID:
9506477
44.

Direct effects of leptin on brown and white adipose tissue.

Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, Boss O, Pernin A, Chin WW, Cusin I, Rohner-Jeanrenaud F, Burger AG, Zapf J, Meier CA.

J Clin Invest. 1997 Dec 1;100(11):2858-64.

45.

Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature.

Boss O, Samec S, Kühne F, Bijlenga P, Assimacopoulos-Jeannet F, Seydoux J, Giacobino JP, Muzzin P.

J Biol Chem. 1998 Jan 2;273(1):5-8.

46.

Quantification of the full length leptin receptor (OB-Rb) in human brown and white adipose tissue.

Kutoh E, Boss O, Levasseur F, Giacobino JP.

Life Sci. 1998;62(5):445-51.

PMID:
9449235
47.

Targeted gene disruption reveals a leptin-independent role for the mouse beta3-adrenoceptor in the regulation of body composition.

Revelli JP, Preitner F, Samec S, Muniesa P, Kuehne F, Boss O, Vassalli JD, Dulloo A, Seydoux J, Giacobino JP, Huarte J, Ody C.

J Clin Invest. 1997 Sep 1;100(5):1098-106.

48.

Tissue-dependent upregulation of rat uncoupling protein-2 expression in response to fasting or cold.

Boss O, Samec S, Dulloo A, Seydoux J, Muzzin P, Giacobino JP.

FEBS Lett. 1997 Jul 21;412(1):111-4.

49.

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression.

Boss O, Samec S, Paoloni-Giacobino A, Rossier C, Dulloo A, Seydoux J, Muzzin P, Giacobino JP.

FEBS Lett. 1997 May 12;408(1):39-42.

50.

Effects of beta-adrenoceptor subtype stimulation on obese gene messenger ribonucleic acid and on leptin secretion in mouse brown adipocytes differentiated in culture.

Deng C, Moinat M, Curtis L, Nadakal A, Preitner F, Boss O, Assimacopoulos-Jeannet F, Seydoux J, Giacobino JP.

Endocrinology. 1997 Feb;138(2):548-52.

PMID:
9002984

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