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Items: 40


A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death.

Bosnakovski D, da Silva MT, Sunny ST, Ener ET, Toso EA, Yuan C, Cui Z, Walters MA, Jadhav A, Kyba M.

Sci Adv. 2019 Sep 11;5(9):eaaw7781. doi: 10.1126/sciadv.aaw7781. eCollection 2019 Sep.


n-3 polyunsaturated fatty acids provoke a specific transcriptional profile in rabbit adipose-derived stem cells in vitro.

Vackova E, Bosnakovski D, Bjørndal B, Yonkova P, Grigorova N, Ivanova Z, Penchev G, Simeonova G, Miteva L, Milanova A, Vachkova T, Stanilova S, Penchev Georgiev I.

J Anim Physiol Anim Nutr (Berl). 2019 May;103(3):925-934. doi: 10.1111/jpn.13075. Epub 2019 Feb 28.


Contemporary Formulations for Drug Delivery of Anticancer Bioactive Compounds.

Ackova DG, Smilkov K, Bosnakovski D.

Recent Pat Anticancer Drug Discov. 2019;14(1):19-31. doi: 10.2174/1574892814666190111104834. Review.


Inflammatory Cytokines and Biodegradable Scaffolds in Dental Mesenchymal Stem Cells Priming.

Kanjevac T, Gustafson C, Ivanovska A, Ravanetti F, Cacchioli A, Bosnakovski D.

Curr Stem Cell Res Ther. 2019;14(4):320-326. doi: 10.2174/1574888X14666190103170109. Review.


Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.

Lee JK, Bosnakovski D, Toso EA, Dinh T, Banerjee S, Bohl TE, Shi K, Orellana K, Kyba M, Aihara H.

Cell Rep. 2018 Dec 11;25(11):2955-2962.e3. doi: 10.1016/j.celrep.2018.11.060.


Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression.

Bosnakovski D, Gearhart MD, Toso EA, Ener ET, Choi SH, Kyba M.

Sci Rep. 2018 Nov 16;8(1):16957. doi: 10.1038/s41598-018-35150-8.


Comment on structural basis of DUX4/IGH-driven transactivation.

Aihara H, Shi K, Lee JK, Bosnakovski D, Kyba M.

Leukemia. 2018 Sep;32(9):2090-2092. doi: 10.1038/s41375-018-0217-7. Epub 2018 Jul 27. No abstract available.


Author Correction: Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model.

Bosnakovski D, Chan SSK, Recht OO, Hartweck LM, Gustafson CJ, Athman LL, Lowe DA, Kyba M.

Nat Commun. 2018 Feb 22;9(1):856. doi: 10.1038/s41467-018-03449-9.


The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain.

Bosnakovski D, Toso EA, Hartweck LM, Magli A, Lee HA, Thompson ER, Dandapat A, Perlingeiro RCR, Kyba M.

J Cell Sci. 2017 Nov 1;130(21):3685-3697. doi: 10.1242/jcs.205427. Epub 2017 Sep 21.


Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model.

Bosnakovski D, Chan SSK, Recht OO, Hartweck LM, Gustafson CJ, Athman LL, Lowe DA, Kyba M.

Nat Commun. 2017 Sep 15;8(1):550. doi: 10.1038/s41467-017-00730-1. Erratum in: Nat Commun. 2018 Feb 22;9(1):856.


p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.

Bosnakovski D, Gearhart MD, Toso EA, Recht OO, Cucak A, Jain AK, Barton MC, Kyba M.

Dis Model Mech. 2017 Oct 1;10(10):1211-1216. doi: 10.1242/dmm.030064. Epub 2017 Jul 28.


Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen.

Choi SH, Bosnakovski D, Strasser JM, Toso EA, Walters MA, Kyba M.

J Biomol Screen. 2016 Aug;21(7):680-8. doi: 10.1177/1087057116651868. Epub 2016 May 31.


Adipogenic potential of stem cells derived from rabbit subcutaneous and visceral adipose tissue in vitro.

Vachkova E, Bosnakovski D, Yonkova P, Grigorova N, Ivanova Zh, Todorov P, Penchev G, Milanova A, Simeonova G, Stanilova S, Georgiev IP.

In Vitro Cell Dev Biol Anim. 2016 Sep;52(8):829-37. doi: 10.1007/s11626-016-0048-7. Epub 2016 May 12.


DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

Choi SH, Gearhart MD, Cui Z, Bosnakovski D, Kim M, Schennum N, Kyba M.

Nucleic Acids Res. 2016 Jun 20;44(11):5161-73. doi: 10.1093/nar/gkw141. Epub 2016 Mar 6.


Perspectives in Engineered Mesenchymal Stem/Stromal Cells Based Anti- Cancer Drug Delivery Systems.

Ackova DG, Kanjevac T, Rimondini L, Bosnakovski D.

Recent Pat Anticancer Drug Discov. 2016;11(1):98-111. Review.


Dominant lethal pathologies in male mice engineered to contain an X-linked DUX4 transgene.

Dandapat A, Bosnakovski D, Hartweck LM, Arpke RW, Baltgalvis KA, Vang D, Baik J, Darabi R, Perlingeiro RC, Hamra FK, Gupta K, Lowe DA, Kyba M.

Cell Rep. 2014 Sep 11;8(5):1484-96. doi: 10.1016/j.celrep.2014.07.056. Epub 2014 Aug 28.


High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity.

Bosnakovski D, Choi SH, Strasser JM, Toso EA, Walters MA, Kyba M.

Skelet Muscle. 2014 Feb 1;4(1):4. doi: 10.1186/2044-5040-4-4.


Mesenchymal stem cells for anti-cancer drug delivery.

Gjorgieva D, Zaidman N, Bosnakovski D.

Recent Pat Anticancer Drug Discov. 2013 Sep;8(3):310-8. Review.


Expression of the human FSHD-linked DUX4 gene induces neurogenesis during differentiation of murine embryonic stem cells.

Dandapat A, Hartweck LM, Bosnakovski D, Kyba M.

Stem Cells Dev. 2013 Sep 1;22(17):2440-8. doi: 10.1089/scd.2012.0643. Epub 2013 May 9.


Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells.

Iacovino M, Bosnakovski D, Fey H, Rux D, Bajwa G, Mahen E, Mitanoska A, Xu Z, Kyba M.

Stem Cells. 2011 Oct;29(10):1580-8.


Decreased proliferation kinetics of mouse myoblasts overexpressing FRG1.

Chen SC, Frett E, Marx J, Bosnakovski D, Reed X, Kyba M, Kennedy BK.

PLoS One. 2011;6(5):e19780. doi: 10.1371/journal.pone.0019780. Epub 2011 May 16.


Functional myogenic engraftment from mouse iPS cells.

Darabi R, Pan W, Bosnakovski D, Baik J, Kyba M, Perlingeiro RC.

Stem Cell Rev Rep. 2011 Nov;7(4):948-57. doi: 10.1007/s12015-011-9258-2.


Biphasic myopathic phenotype of mouse DUX, an ORF within conserved FSHD-related repeats.

Bosnakovski D, Daughters RS, Xu Z, Slack JM, Kyba M.

PLoS One. 2009 Sep 16;4(9):e7003. doi: 10.1371/journal.pone.0007003.


Engraftment of mesenchymal stem cells into dystrophin-deficient mice is not accompanied by functional recovery.

Gang EJ, Darabi R, Bosnakovski D, Xu Z, Kamm KE, Kyba M, Perlingeiro RC.

Exp Cell Res. 2009 Sep 10;315(15):2624-36. doi: 10.1016/j.yexcr.2009.05.009. Epub 2009 May 19.


An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies.

Bosnakovski D, Xu Z, Gang EJ, Galindo CL, Liu M, Simsek T, Garner HR, Agha-Mohammadi S, Tassin A, Coppée F, Belayew A, Perlingeiro RR, Kyba M.

EMBO J. 2008 Oct 22;27(20):2766-79. doi: 10.1038/emboj.2008.201. Epub 2008 Oct 2.


Prospective isolation of skeletal muscle stem cells with a Pax7 reporter.

Bosnakovski D, Xu Z, Li W, Thet S, Cleaver O, Perlingeiro RC, Kyba M.

Stem Cells. 2008 Dec;26(12):3194-204. doi: 10.1634/stemcells.2007-1017. Epub 2008 Sep 18.


White fat progenitor cells reside in the adipose vasculature.

Tang W, Zeve D, Suh JM, Bosnakovski D, Kyba M, Hammer RE, Tallquist MD, Graff JM.

Science. 2008 Oct 24;322(5901):583-6. doi: 10.1126/science.1156232. Epub 2008 Sep 18.


DUX4c, an FSHD candidate gene, interferes with myogenic regulators and abolishes myoblast differentiation.

Bosnakovski D, Lamb S, Simsek T, Xu Z, Belayew A, Perlingeiro R, Kyba M.

Exp Neurol. 2008 Nov;214(1):87-96. doi: 10.1016/j.expneurol.2008.07.022. Epub 2008 Aug 6.


Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage.

Gang EJ, Bosnakovski D, Simsek T, To K, Perlingeiro RC.

Exp Cell Res. 2008 May 1;314(8):1721-33. doi: 10.1016/j.yexcr.2008.02.016. Epub 2008 Mar 5.


SSEA-4 identifies mesenchymal stem cells from bone marrow.

Gang EJ, Bosnakovski D, Figueiredo CA, Visser JW, Perlingeiro RC.

Blood. 2007 Feb 15;109(4):1743-51. Epub 2006 Oct 24.


Gene expression profile of bovine bone marrow mesenchymal stem cell during spontaneous chondrogenic differentiation in pellet culture system.

Bosnakovski D, Mizuno M, Kim G, Takagi S, Okumur M, Fujinag T.

Jpn J Vet Res. 2006 Feb;53(3-4):127-39.


Matrix metalloproteinase inhibitor RECK expression in canine tumors.

Takagi S, Kato Y, Asano K, Ohsaki T, Bosnakovski D, Hoshino Y, Okumura M, Kadosawa T, Fujinaga T.

J Vet Med Sci. 2005 Aug;67(8):761-7.


Molecular cloning of canine membrane-anchored inhibitor of matrix metalloproteinase, RECK.

Takagi S, Kitamura T, Hosaka Y, Ohsaki T, Bosnakovski D, Kadosawa T, Okumura M, Fujinaga T.

J Vet Med Sci. 2005 Apr;67(4):385-91.


Isolation and multilineage differentiation of bovine bone marrow mesenchymal stem cells.

Bosnakovski D, Mizuno M, Kim G, Takagi S, Okumura M, Fujinaga T.

Cell Tissue Res. 2005 Feb;319(2):243-53. Epub 2004 Nov 20.


Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells in pellet cultural system.

Bosnakovski D, Mizuno M, Kim G, Ishiguro T, Okumura M, Iwanaga T, Kadosawa T, Fujinaga T.

Exp Hematol. 2004 May;32(5):502-9.


Regeneration of cartilage tissue by autologous chondrocytes transplantation for cartilage defects in a experimental bovine model.

Kim G, Okumura M, Bosnakovski D, Ishiguro T, Kadosawa T, Fujinaga T.

J Vet Med Sci. 2004 Mar;66(3):263-7.


Biological properties of allogenic articular chondrocytes on the surface of bovine cartilage explants in vitro.

Kim G, Okumura M, Bosnakovski D, Ishiguro T, Kadosawa T, Fujinaga T.

J Vet Med A Physiol Pathol Clin Med. 2003 Oct;50(8):418-23.


Effects of ascorbic acid on proliferation and biological properties of bovine chondrocytes in alginate beads.

Kim G, Okumura M, Bosnakovski D, Ishiguro T, Park CH, Kadosawa T, Fujinaga T.

Jpn J Vet Res. 2003 Aug;51(2):83-94.


Relationship of disease progression and plasma histamine concentrations in 11 dogs with mast cell tumors.

Ishiguro T, Kadosawa T, Takagi S, Kim G, Ohsaki T, Bosnakovski D, Okumura M, Fujinaga T.

J Vet Intern Med. 2003 Mar-Apr;17(2):194-8.

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