Sort by
Items per page

Send to

Choose Destination

Search results

Items: 12


RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer.

Šuštić T, Bosdriesz E, van Wageningen S, Wessels LFA, Bernards R.

Transl Oncol. 2019 Dec 19;13(2):201-211. doi: 10.1016/j.tranon.2019.10.006. [Epub ahead of print]


A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

Šuštić T, van Wageningen S, Bosdriesz E, Reid RJD, Dittmar J, Lieftink C, Beijersbergen RL, Wessels LFA, Rothstein R, Bernards R.

Genome Med. 2018 Nov 27;10(1):90. doi: 10.1186/s13073-018-0600-z.


Comparative Network Reconstruction using mixed integer programming.

Bosdriesz E, Prahallad A, Klinger B, Sieber A, Bosma A, Bernards R, Blüthgen N, Wessels LFA.

Bioinformatics. 2018 Sep 1;34(17):i997-i1004. doi: 10.1093/bioinformatics/bty616.


A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.

Ressa A, Bosdriesz E, de Ligt J, Mainardi S, Maddalo G, Prahallad A, Jager M, de la Fonteijne L, Fitzpatrick M, Groten S, Altelaar AFM, Bernards R, Cuppen E, Wessels L, Heck AJR.

Mol Cell Proteomics. 2018 Oct;17(10):1892-1908. doi: 10.1074/mcp.RA117.000486. Epub 2018 Jul 3.


Modelling signalling networks from perturbation data.

Dorel M, Klinger B, Gross T, Sieber A, Prahallad A, Bosdriesz E, Wessels LFA, Blüthgen N.

Bioinformatics. 2018 Dec 1;34(23):4079-4086. doi: 10.1093/bioinformatics/bty473.


MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

Xue Z, Vis DJ, Bruna A, Sustic T, van Wageningen S, Batra AS, Rueda OM, Bosdriesz E, Caldas C, Wessels LFA, Bernards R.

Cell Res. 2018 Jul;28(7):719-729. doi: 10.1038/s41422-018-0044-4. Epub 2018 May 24.


An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.

Wang L, Leite de Oliveira R, Huijberts S, Bosdriesz E, Pencheva N, Brunen D, Bosma A, Song JY, Zevenhoven J, Los-de Vries GT, Horlings H, Nuijen B, Beijnen JH, Schellens JHM, Bernards R.

Cell. 2018 May 31;173(6):1413-1425.e14. doi: 10.1016/j.cell.2018.04.012. Epub 2018 May 10.


Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux.

Bosdriesz E, Wortel MT, Haanstra JR, Wagner MJ, de la Torre Cortés P, Teusink B.

Sci Rep. 2018 Apr 3;8(1):5576. doi: 10.1038/s41598-018-23528-7.


Evolutionary pressures on microbial metabolic strategies in the chemostat.

Wortel MT, Bosdriesz E, Teusink B, Bruggeman FJ.

Sci Rep. 2016 Jul 6;6:29503. doi: 10.1038/srep29503.


Binding proteins enhance specific uptake rate by increasing the substrate-transporter encounter rate.

Bosdriesz E, Magnúsdóttir S, Bruggeman FJ, Teusink B, Molenaar D.

FEBS J. 2015 Jun;282(12):2394-407. doi: 10.1111/febs.13289. Epub 2015 Apr 24.


How fast-growing bacteria robustly tune their ribosome concentration to approximate growth-rate maximization.

Bosdriesz E, Molenaar D, Teusink B, Bruggeman FJ.

FEBS J. 2015 May;282(10):2029-44. doi: 10.1111/febs.13258. Epub 2015 Mar 26.


How biochemical constraints of cellular growth shape evolutionary adaptations in metabolism.

Berkhout J, Bosdriesz E, Nikerel E, Molenaar D, de Ridder D, Teusink B, Bruggeman FJ.

Genetics. 2013 Jun;194(2):505-12. doi: 10.1534/genetics.113.150631. Epub 2013 Mar 27.

Supplemental Content

Loading ...
Support Center