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Items: 33

1.

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.

Boudny M, Zemanova J, Khirsariya P, Borsky M, Verner J, Cerna J, Oltova A, Seda V, Mraz M, Jaros J, Jaskova Z, Spunarova M, Brychtova Y, Soucek K, Drapela S, Kasparkova M, Mayer J, Paruch K, Trbusek M.

Haematologica. 2019 Apr 11. pii: haematol.2018.203430. doi: 10.3324/haematol.2018.203430. [Epub ahead of print]

2.

Rituximab primarily targets an intra-clonal BCR signaling proficient CLL subpopulation characterized by high CD20 levels.

Pavlasova G, Borsky M, Svobodova V, Oppelt J, Cerna K, Novotna J, Seda V, Fojtova M, Fajkus J, Brychtova Y, Doubek M, Pospisilova S, Mayer J, Mraz M.

Leukemia. 2018 Sep;32(9):2028-2031. doi: 10.1038/s41375-018-0211-0. Epub 2018 Jul 20. No abstract available.

PMID:
30030508
3.

Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL.

Brazdilova K, Plevova K, Skuhrova Francova H, Kockova H, Borsky M, Bikos V, Malcikova J, Oltova A, Kotaskova J, Tichy B, Brychtova Y, Mayer J, Doubek M, Pospisilova S.

Leukemia. 2018 Jan;32(1):234-236. doi: 10.1038/leu.2017.274. Epub 2017 Aug 29. No abstract available.

4.

Decreased WNT3 expression in chronic lymphocytic leukaemia is a hallmark of disease progression and identifies patients with worse prognosis in the subgroup with mutated IGHV.

Poppova L, Janovska P, Plevova K, Radova L, Plesingerova H, Borsky M, Kotaskova J, Kantorova B, Hlozkova M, Figulova J, Brychtova Y, Machalova M, Urik M, Doubek M, Kozubik A, Pospisilova S, Pavlova S, Bryja V.

Br J Haematol. 2016 Dec;175(5):851-859. doi: 10.1111/bjh.14312. Epub 2016 Sep 21.

PMID:
27651098
5.

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.

Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, Paruch K, Trbusek M.

Oncotarget. 2016 Sep 20;7(38):62091-62106. doi: 10.18632/oncotarget.11388.

6.

Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis.

Pavlasova G, Borsky M, Seda V, Cerna K, Osickova J, Doubek M, Mayer J, Calogero R, Trbusek M, Pospisilova S, Davids MS, Kipps TJ, Brown JR, Mraz M.

Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1.

7.

Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients.

Kantorova B, Malcikova J, Brazdilova K, Borsky M, Plevova K, Smardova J, Radova L, Tom N, Trbusek M, Diviskova E, Francova HS, Navrkalova V, Doubek M, Brychtova Y, Mayer J, Pospisilova S.

Br J Haematol. 2017 Sep;178(6):979-982. doi: 10.1111/bjh.14176. Epub 2016 Jul 29. No abstract available.

PMID:
27470445
8.

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects.

Culen M, Borsky M, Nemethova V, Razga F, Smejkal J, Jurcek T, Dvorakova D, Zackova D, Weinbergerova B, Semerad L, Sadovnik I, Eisenwort G, Herrmann H, Valent P, Mayer J, Racil Z.

Oncotarget. 2016 May 31;7(22):33016-24. doi: 10.18632/oncotarget.9108.

9.

Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.

Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V.

Clin Cancer Res. 2016 Jan 15;22(2):459-69. doi: 10.1158/1078-0432.CCR-15-0154. Epub 2015 Aug 3.

10.

BCR-ABL1 kinase domain mutational analysis of CD34+ stem/progenitor cells in newly diagnosed CML patients by next-generation sequencing.

Musilova M, Razga F, Jurcek T, Jeziskova I, Borsky M, Nemethova V, Zackova D, Culen M, Dvorakova D, Mayer J, Racil Z.

Am J Hematol. 2014 Oct;89(10):1016-7. doi: 10.1002/ajh.23794. Epub 2014 Jul 22. No abstract available.

11.

Distinct in vitro sensitivity of p53-mutated and ATM-mutated chronic lymphocytic leukemia cells to ofatumumab and rituximab.

Sebejova L, Borsky M, Jaskova Z, Potesil D, Navrkalova V, Malcikova J, Sramek M, Doubek M, Loja T, Pospisilova S, Mayer J, Trbusek M.

Exp Hematol. 2014 Oct;42(10):867-74.e1. doi: 10.1016/j.exphem.2014.06.003. Epub 2014 Jun 23.

PMID:
24970561
12.

Prospective analysis of low-level BCR-ABL1 T315I mutation in CD34 + cells of patients with de novo chronic myeloid leukemia.

Jurcek T, Razga F, Mazancova P, Musilova M, Dvorakova D, Borsky M, Zackova D, Dobesova B, Semerad L, Mayer J, Racil Z.

Leuk Lymphoma. 2014 Aug;55(8):1915-7. doi: 10.3109/10428194.2013.842988. Epub 2014 Feb 6. No abstract available.

PMID:
24304421
13.

Detecting minimal residual disease in patients with chronic lymphocytic leukemia using 8-color flow cytometry protocol in routine hematological practice.

Stehlíková O, Chovancová J, Tichý B, Krejčí M, Brychtová Y, Panovská A, Francová Skuhrová H, Burčková K, Borský M, Loja T, Mayer J, Pospíšilová S, Doubek M.

Int J Lab Hematol. 2014 Apr;36(2):165-71. doi: 10.1111/ijlh.12149. Epub 2013 Sep 13.

PMID:
24028768
14.

The origin of deletion 22q11 in chronic lymphocytic leukemia is related to the rearrangement of immunoglobulin lambda light chain locus.

Mraz M, Stano Kozubik K, Plevova K, Musilova K, Tichy B, Borsky M, Kuglik P, Doubek M, Brychtova Y, Mayer J, Pospisilova S.

Leuk Res. 2013 Jul;37(7):802-8. doi: 10.1016/j.leukres.2013.03.018. Epub 2013 Apr 20.

PMID:
23608880
15.

Clonal heterogeneity in patients with cytogenetically normal acute myeloid leukemia with NPM1 mutations.

Dvorakova D, Racil Z, Borsky M, Robesova B, Jeziskova I, Razga F, Lengerova M, Mayer J.

Leuk Lymphoma. 2013 May;54(5):1056-60. doi: 10.3109/10428194.2012.734618. Epub 2012 Oct 16.

PMID:
23020761
16.

Analysis of mutations in the BCR-ABL1 kinase domain, using direct sequencing: detection of the T315I mutation in bone marrow CD34+ cells of a patient with chronic myelogenous leukemia 6 months prior to its emergence in peripheral blood.

Razga F, Jurcek T, Jeziskova I, Zackova D, Dvorakova D, Borsky M, Mayer J, Racil Z.

Mol Diagn Ther. 2012 Jun 1;16(3):163-6. doi: 10.2165/11632420-000000000-00000.

PMID:
22489663
17.

MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia.

Mraz M, Dolezalova D, Plevova K, Stano Kozubik K, Mayerova V, Cerna K, Musilova K, Tichy B, Pavlova S, Borsky M, Verner J, Doubek M, Brychtova Y, Trbusek M, Hampl A, Mayer J, Pospisilova S.

Blood. 2012 Mar 1;119(9):2110-3. doi: 10.1182/blood-2011-11-394874. Epub 2012 Jan 10.

18.

Increasing hematopoietic microchimerism is a reliable indicator of incipient AML relapse.

Horky O, Mayer J, Kablaskova L, Razga F, Krejci M, Kissova J, Borsky M, Jeziskova I, Dvorakova D.

Int J Lab Hematol. 2011 Feb;33(1):57-66. doi: 10.1111/j.1751-553X.2010.01249.x.

PMID:
20681999
19.

Detection and treatment of molecular relapse in acute myeloid leukemia with RUNX1 (AML1), CBFB, or MLL gene translocations: frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.

Doubek M, Palasek I, Pospisil Z, Borsky M, Klabusay M, Brychtova Y, Jurcek T, Jeziskova I, Krejci M, Dvorakova D, Mayer J.

Exp Hematol. 2009 Jun;37(6):659-72. doi: 10.1016/j.exphem.2009.03.004.

PMID:
19463768
20.

Inactivation of p53 and amplification of MYCN gene in a terminal lymphoblastic relapse in a chronic lymphocytic leukemia patient.

Stano-Kozubik K, Malcikova J, Tichy B, Kotaskova J, Borsky M, Hrabcakova V, Francova H, Valaskova I, Bourkova L, Smardova J, Doubek M, Brychtova Y, Pospisilova S, Mayer J, Trbusek M.

Cancer Genet Cytogenet. 2009 Feb;189(1):53-8. doi: 10.1016/j.cancergencyto.2008.10.003.

PMID:
19167613
21.

Presence of heterozygous ATM deletion may not be critical in the primary response of chronic lymphocytic leukemia cells to fludarabine.

Cejkova S, Rocnova L, Potesil D, Smardova J, Novakova V, Chumchalova J, Zezulkova D, Borsky M, Doubek M, Brychtova Y, Pospisilova S, Klabusay M, Mayer J, Trbusek M.

Eur J Haematol. 2009 Feb;82(2):133-42. doi: 10.1111/j.1600-0609.2008.01177.x. Epub 2008 Nov 6.

PMID:
19018867
22.

Mutation analysis of the ATP7B gene and genotype/phenotype correlation in 227 patients with Wilson disease.

Vrabelova S, Letocha O, Borsky M, Kozak L.

Mol Genet Metab. 2005 Sep-Oct;86(1-2):277-85. Epub 2005 Jun 20.

PMID:
15967699
23.

Telomerase as a diagnostic and predictive marker in colorectal carcinoma.

Maláska J, Kunická Z, Borský M, Sklenicková M, Novotná M, Fajkusová L, Zaloudík J, Fajkus J.

Neoplasma. 2004;51(2):90-6.

PMID:
15190417
24.

Changes in telomerase activity, expression and splicing in response to differentiation of normal and carcinoma colon cells.

Fajkus J, Borsky M, Kunická Z, Kovaríková M, Dvoráková D, Hofmanová J, Kozubík A.

Anticancer Res. 2003 Mar-Apr;23(2B):1605-12.

PMID:
12820429
25.

[Direct DNA diagnosis of Friedreich's ataxia].

Borský M, Pekarík V, Tvrdíková M, Kozák L.

Cas Lek Cesk. 1999 Oct 20;138(18):557-9. Czech.

PMID:
10596471
26.

[Does insurance status have an effect on frequency of appendectomies?].

Borsky M, Gutzwiller F.

Schweiz Med Wochenschr. 1994 Sep 17;124(37):1619-25. German.

PMID:
7939529
27.

[Long-term results of replacement of the head of the radius with a silastic prosthesis].

Borsky M, Marty A.

Z Unfallchir Versicherungsmed. 1993;86(1):40-5. German.

PMID:
8357687
28.

[Acute ischemia syndrome: analysis of 144 cases].

Duff C, Borsky M, Simmen HP, von Segesser L, Turina M.

Vasa Suppl. 1989;27:233-4. German. No abstract available.

PMID:
2623503
29.

Arotinoid acid (Ro 13-7410): a pilot study in dermatology.

Saurat JH, Mérot Y, Borsky M, Abba Z, Hirschel-Scholz S.

Dermatologica. 1988;176(4):191-9.

PMID:
3378655
30.

[Osteomalacia following gastrectomy. A case report].

Borsky M, Ritter R.

Schweiz Rundsch Med Prax. 1986 Oct 7;75(41):1206-9. German. No abstract available.

PMID:
3024284
31.

[Microsporosis familiaris (author's transl)].

Kejda J, Borský M, Spousta J.

Cesk Dermatol. 1981 Aug;56(4):252-5. Czech. No abstract available.

PMID:
7273163
32.

[Melanosis Becker (author's transl)].

Schwank R, Borský M, Vosmík F.

Cesk Dermatol. 1977 Mar;52(2):115-20. Czech. No abstract available.

PMID:
890749
33.

[Relationship between dental and bone maturation].

Bleha P, Havlík J, Borský M, Pelech L.

Cesk Stomatol. 1976 Jan;76(1):15-24. Czech. No abstract available.

PMID:
175961

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