Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 123

1.

A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion.

Boone PG, Rochelle LK, Ginzel JD, Lubkov V, Roberts WL, Nicholls PJ, Bock C, Flowers ML, von Furstenberg RJ, Stripp BR, Agarwal P, Borowsky AD, Cardiff RD, Barak LS, Caron MG, Lyerly HK, Snyder JC.

Nat Commun. 2019 Dec 2;10(1):5490. doi: 10.1038/s41467-019-13330-y.

2.

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.

Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW.

Nat Commun. 2019 Oct 11;10(1):4621. doi: 10.1038/s41467-019-12529-3.

3.

Tumor-specific delivery of gemcitabine with activatable liposomes.

Tucci ST, Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Foiret J, Hubbard NE, Borowsky AD, Baikoghli M, Cheng RH, Ferrara KW.

J Control Release. 2019 Sep 10;309:277-288. doi: 10.1016/j.jconrel.2019.07.014. Epub 2019 Jul 10.

PMID:
31301340
4.

Cancer overdiagnosis: a biological challenge and clinical dilemma.

Srivastava S, Koay EJ, Borowsky AD, De Marzo AM, Ghosh S, Wagner PD, Kramer BS.

Nat Rev Cancer. 2019 Jun;19(6):349-358. doi: 10.1038/s41568-019-0142-8. Review.

PMID:
31024081
5.

Combining activatable nanodelivery with immunotherapy in a murine breast cancer model.

Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Ferrara KW.

J Control Release. 2019 Jun 10;303:42-54. doi: 10.1016/j.jconrel.2019.04.008. Epub 2019 Apr 9.

PMID:
30978432
6.

A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials.

Pénzváltó Z, Chen JQ, Tepper CG, Davis RR, Silvestrini MT, Umeh-Garcia M, Sweeney C, Borowsky AD.

J Mammary Gland Biol Neoplasia. 2019 Jun;24(2):149-162. doi: 10.1007/s10911-019-09425-3. Epub 2019 Feb 27.

PMID:
30810966
7.

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation.

Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW.

Theranostics. 2018 Jun 7;8(13):3611-3628. doi: 10.7150/thno.25613. eCollection 2018.

8.

CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols.

Seo JW, Tavaré R, Mahakian LM, Silvestrini MT, Tam S, Ingham ES, Salazar FB, Borowsky AD, Wu AM, Ferrara KW.

Clin Cancer Res. 2018 Oct 15;24(20):4976-4987. doi: 10.1158/1078-0432.CCR-18-0261. Epub 2018 Jul 2.

9.

Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study.

Suh JH, Degagné É, Gleghorn EE, Setty M, Rodriguez A, Park KT, Verstraete SG, Heyman MB, Patel AS, Irek M, Gildengorin GL, Hubbard NE, Borowsky AD, Saba JD.

Inflamm Bowel Dis. 2018 May 18;24(6):1321-1334. doi: 10.1093/ibd/izy007.

10.

High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia.

Pelissier Vatter FA, Schapiro D, Chang H, Borowsky AD, Lee JK, Parvin B, Stampfer MR, LaBarge MA, Bodenmiller B, Lorens JB.

Cell Rep. 2018 Apr 24;23(4):1205-1219. doi: 10.1016/j.celrep.2018.03.114.

11.

Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression.

Mori H, Cardiff RD, Borowsky AD.

Front Cell Dev Biol. 2018 Mar 29;6:35. doi: 10.3389/fcell.2018.00035. eCollection 2018. Review.

12.

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry.

Gonzalez VD, Samusik N, Chen TJ, Savig ES, Aghaeepour N, Quigley DA, Huang YW, Giangarrà V, Borowsky AD, Hubbard NE, Chen SY, Han G, Ashworth A, Kipps TJ, Berek JS, Nolan GP, Fantl WJ.

Cell Rep. 2018 Feb 13;22(7):1875-1888. doi: 10.1016/j.celrep.2018.01.053.

13.

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.

Lindström LS, Yau C, Czene K, Thompson CK, Hoadley KA, Van't Veer LJ, Balassanian R, Bishop JW, Carpenter PM, Chen YY, Datnow B, Hasteh F, Krings G, Lin F, Zhang Y, Nordenskjöld B, Stål O, Benz CC, Fornander T, Borowsky AD, Esserman LJ; STO Trialists Group.

J Natl Cancer Inst. 2018 Jul 1;110(7):726-733. doi: 10.1093/jnci/djx270.

14.

Microscopy with ultraviolet surface excitation for rapid slide-free histology.

Fereidouni F, Harmany ZT, Tian M, Todd A, Kintner JA, McPherson JD, Borowsky AD, Bishop J, Lechpammer M, Demos SG, Levenson R.

Nat Biomed Eng. 2017 Dec;1(12):957-966. doi: 10.1038/s41551-017-0165-y. Epub 2017 Dec 4.

PMID:
31015706
15.

Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer.

Rowson-Hodel AR, Wald JH, Hatakeyama J, O'Neal WK, Stonebraker JR, VanderVorst K, Saldana MJ, Borowsky AD, Sweeney C, Carraway KL 3rd.

Oncogene. 2018 Jan 11;37(2):197-207. doi: 10.1038/onc.2017.327. Epub 2017 Sep 11.

16.

Pathobiology of the 129:Stat1 -/- mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotype.

Mori H, Chen JQ, Cardiff RD, Pénzváltó Z, Hubbard NE, Schuetter L, Hovey RC, Trott JF, Borowsky AD.

Breast Cancer Res. 2017 Sep 2;19(1):102. doi: 10.1186/s13058-017-0892-8.

17.

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.

Esserman LJ, Yau C, Thompson CK, van 't Veer LJ, Borowsky AD, Hoadley KA, Tobin NP, Nordenskjöld B, Fornander T, Stål O, Benz CC, Lindström LS.

JAMA Oncol. 2017 Nov 1;3(11):1503-1510. doi: 10.1001/jamaoncol.2017.1261. Erratum in: JAMA Oncol. 2017 Nov 1;3(11):1589.

18.

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy.

Sckisel GD, Mirsoian A, Minnar CM, Crittenden M, Curti B, Chen JQ, Blazar BR, Borowsky AD, Monjazeb AM, Murphy WJ.

J Immunother Cancer. 2017 Apr 18;5:33. doi: 10.1186/s40425-017-0235-4. eCollection 2017.

19.

Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin.

Fite BZ, Kheirolomoom A, Foiret JL, Seo JW, Mahakian LM, Ingham ES, Tam SM, Borowsky AD, Curry FE, Ferrara KW.

J Control Release. 2017 Jun 28;256:203-213. doi: 10.1016/j.jconrel.2017.04.007. Epub 2017 Apr 7.

20.

Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW.

JCI Insight. 2017 Mar 23;2(6):e90521. doi: 10.1172/jci.insight.90521.

21.

Microscopy with ultraviolet surface excitation for rapid slide-free histology.

Fereidouni F, Harmany ZT, Tian M, Todd A, Kintner JA, McPherson JD, Borowsky AD, Lechpammer M, Bishop J, Demos SG, Levenson R.

Nat Biomed Eng. 2017;1:957-966. Epub 2017 Dec 4.

22.

Glucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In situ (DCIS) Suggests Metabolic Heterogeneity.

Lobo RC, Hubbard NE, Damonte P, Mori H, Pénzváltó Z, Pham C, Koehne AL, Go AC, Anderson SE, Cala PM, Borowsky AD.

Front Cell Dev Biol. 2016 Aug 31;4:93. doi: 10.3389/fcell.2016.00093. eCollection 2016.

23.

New insight into the role of MMP14 in metabolic balance.

Mori H, Bhat R, Bruni-Cardoso A, Chen EI, Jorgens DM, Coutinho K, Louie K, Bowen BB, Inman JL, Tecca V, Lee SJ, Becker-Weimann S, Northen T, Seiki M, Borowsky AD, Auer M, Bissell MJ.

PeerJ. 2016 Jul 13;4:e2142. doi: 10.7717/peerj.2142. eCollection 2016.

24.

Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study.

Schmitz J, Schwab J, Schwenck J, Chen Q, Quintanilla-Martinez L, Hahn M, Wietek B, Schwenzer N, Staebler A, Kohlhofer U, Aina OH, Hubbard NE, Reischl G, Borowsky AD, Brucker S, Nikolaou K, la Fougère C, Cardiff RD, Pichler BJ, Schmid AM.

Cancer Res. 2016 Sep 15;76(18):5512-22. doi: 10.1158/0008-5472.CAN-15-0642. Epub 2016 Jul 27.

25.

Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.

Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW.

Nat Med. 2016 Jun 7;22(6):692. doi: 10.1038/nm0616-692b. No abstract available.

PMID:
27270780
26.

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.

Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW.

Cancer Lett. 2016 Aug 10;378(2):69-79. doi: 10.1016/j.canlet.2016.05.004. Epub 2016 May 6.

PMID:
27164560
27.

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.

Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW.

Nat Med. 2016 May;22(5):488-96. doi: 10.1038/nm.4070. Epub 2016 Mar 28. Erratum in: Nat Med. 2016 Jun 7;22(6):692.

28.

MAGI-2 in prostate cancer: an immunohistochemical study.

Goldstein J, Borowsky AD, Goyal R, Roland JT, Arnold SA, Gellert LL, Clark PE, Hameed O, Giannico GA.

Hum Pathol. 2016 Jun;52:83-91. doi: 10.1016/j.humpath.2016.01.003. Epub 2016 Feb 4.

PMID:
26980016
29.

184AA3: a xenograft model of ER+ breast adenocarcinoma.

Hines WC, Kuhn I, Thi K, Chu B, Stanford-Moore G, Sampayo R, Garbe JC, Stampfer M, Borowsky AD, Bissell MJ.

Breast Cancer Res Treat. 2016 Jan;155(1):37-52. doi: 10.1007/s10549-015-3649-z. Epub 2015 Dec 12.

30.

Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models.

Wong AW, Fite BZ, Liu Y, Kheirolomoom A, Seo JW, Watson KD, Mahakian LM, Tam SM, Zhang H, Foiret J, Borowsky AD, Ferrara KW.

J Clin Invest. 2016 Jan;126(1):99-111. doi: 10.1172/JCI83312. Epub 2015 Nov 23.

31.

CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.

Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW.

J Control Release. 2015 Dec 28;220(Pt A):253-264. doi: 10.1016/j.jconrel.2015.10.016. Epub 2015 Oct 22.

32.

"Score the Core" Web-based pathologist training tool improves the accuracy of breast cancer IHC4 scoring.

Engelberg JA, Retallack H, Balassanian R, Dowsett M, Zabaglo L, Ram AA, Apple SK, Bishop JW, Borowsky AD, Carpenter PM, Chen YY, Datnow B, Elson S, Hasteh F, Lin F, Moatamed NA, Zhang Y, Cardiff RD.

Hum Pathol. 2015 Nov;46(11):1694-704. doi: 10.1016/j.humpath.2015.07.008. Epub 2015 Jul 29.

PMID:
26410019
33.

Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo.

Rowson-Hodel AR, Manjarin R, Trott JF, Cardiff RD, Borowsky AD, Hovey RC.

BMC Cancer. 2015 Jul 31;15:562. doi: 10.1186/s12885-015-1572-7.

34.

Introduction of Zinc-salt Fixation for Effective Detection of Immune Cell-related Markers by Immunohistochemistry.

Mori H, Soonsawad P, Schuetter L, Chen Q, Hubbard NE, Cardiff RD, Borowsky AD.

Toxicol Pathol. 2015 Aug;43(6):883-9. doi: 10.1177/0192623315587593. Epub 2015 Jul 7.

35.

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.

Chen JQ, Mori H, Cardiff RD, Trott JF, Hovey RC, Hubbard NE, Engelberg JA, Tepper CG, Willis BJ, Khan IH, Ravindran RK, Chan SR, Schreiber RD, Borowsky AD.

PLoS One. 2015 Jun 15;10(6):e0129895. doi: 10.1371/journal.pone.0129895. eCollection 2015.

36.

Ultrasound molecular imaging of tumor angiogenesis with a neuropilin-1-targeted microbubble.

Zhang H, Tam S, Ingham ES, Mahakian LM, Lai CY, Tumbale SK, Teesalu T, Hubbard NE, Borowsky AD, Ferrara KW.

Biomaterials. 2015 Jul;56:104-13. doi: 10.1016/j.biomaterials.2015.03.043. Epub 2015 Apr 16.

37.

Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging.

Levenson RM, Borowsky AD, Angelo M.

Lab Invest. 2015 Apr;95(4):397-405. doi: 10.1038/labinvest.2015.2. Epub 2015 Mar 2. Review.

38.

Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells.

Candas D, Lu CL, Fan M, Chuang FY, Sweeney C, Borowsky AD, Li JJ.

Cancer Res. 2014 Dec 15;74(24):7498-509. doi: 10.1158/0008-5472.CAN-14-0844. Epub 2014 Nov 6.

39.

Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.

Veiseh M, Kwon DH, Borowsky AD, Tolg C, Leong HS, Lewis JD, Turley EA, Bissell MJ.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1731-9. doi: 10.1073/pnas.1402383111. Epub 2014 Apr 14.

40.

Multiplexed ion beam imaging of human breast tumors.

Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, Natkunam Y, Nolan GP.

Nat Med. 2014 Apr;20(4):436-42. doi: 10.1038/nm.3488. Epub 2014 Mar 2.

41.

At last: classification of human mammary cells elucidates breast cancer origins.

Cardiff RD, Borowsky AD.

J Clin Invest. 2014 Feb;124(2):478-80. doi: 10.1172/JCI73910. Epub 2014 Jan 27.

42.

Mouse models of prostate cancer: picking the best model for the question.

Grabowska MM, DeGraff DJ, Yu X, Jin RJ, Chen Z, Borowsky AD, Matusik RJ.

Cancer Metastasis Rev. 2014 Sep;33(2-3):377-97. doi: 10.1007/s10555-013-9487-8. Review.

43.

A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice.

Lehoczky JA, Thomas PE, Patrie KM, Owens KM, Villarreal LM, Galbraith K, Washburn J, Johnson CN, Gavino B, Borowsky AD, Millen KJ, Wakenight P, Law W, Van Keuren ML, Gavrilina G, Hughes ED, Saunders TL, Brihn L, Nadeau JH, Innis JW.

PLoS Genet. 2013;9(12):e1003967. doi: 10.1371/journal.pgen.1003967. Epub 2013 Dec 5.

44.

Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors.

Sun F, Chen HG, Li W, Yang X, Wang X, Jiang R, Guo Z, Chen H, Huang J, Borowsky AD, Qiu Y.

J Biol Chem. 2014 Jan 17;289(3):1529-39. doi: 10.1074/jbc.M113.492140. Epub 2013 Dec 2.

45.

Transgenic mammary epithelial osteopontin (spp1) expression induces proliferation and alveologenesis.

Hubbard NE, Chen QJ, Sickafoose LK, Wood MB, Gregg JP, Abrahamsson NM, Engelberg JA, Walls JE, Borowsky AD.

Genes Cancer. 2013 May;4(5-6):201-12. doi: 10.1177/1947601913496813.

46.

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y.

J Biol Chem. 2013 Jul 5;288(27):19593-603. doi: 10.1074/jbc.M113.470872. Epub 2013 May 21.

47.

Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers.

Cardiff RD, Hubbard NE, Engelberg JA, Munn RJ, Miller CH, Walls JE, Chen JQ, Velásquez-García HA, Galvez JJ, Bell KJ, Beckett LA, Li YJ, Borowsky AD.

Lab Invest. 2013 Apr;93(4):480-97. doi: 10.1038/labinvest.2013.10. Epub 2013 Feb 11.

48.

Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS.

Buckle T, Kuil J, van den Berg NS, Bunschoten A, Lamb HJ, Yuan H, Josephson L, Jonkers J, Borowsky AD, van Leeuwen FW.

PLoS One. 2013;8(1):e48324. doi: 10.1371/journal.pone.0048324. Epub 2013 Jan 11.

49.

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW.

Am J Nucl Med Mol Imaging. 2012;2(1):99-109. Epub 2011 Dec 15.

50.

Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex.

Duan Z, Zou JX, Yang P, Wang Y, Borowsky AD, Gao AC, Chen HW.

Prostate. 2013 Apr;73(5):455-66. doi: 10.1002/pros.22587. Epub 2012 Oct 4.

PMID:
23038103

Supplemental Content

Loading ...
Support Center