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Items: 11

1.

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer.

Borovski T, Vellinga TT, Laoukili J, Santo EE, Fatrai S, van Schelven S, Verheem A, Marvin DL, Ubink I, Borel Rinkes IHM, Kranenburg O.

Gut. 2017 Jun;66(6):1106-1115. doi: 10.1136/gutjnl-2016-311547. Epub 2016 Sep 26.

PMID:
27670374
2.

Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF.

Fessler E, Borovski T, Medema JP.

Mol Cancer. 2015 Aug 19;14:157. doi: 10.1186/s12943-015-0420-3.

3.

SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer.

Vellinga TT, Borovski T, de Boer VC, Fatrai S, van Schelven S, Trumpi K, Verheem A, Snoeren N, Emmink BL, Koster J, Rinkes IH, Kranenburg O.

Clin Cancer Res. 2015 Jun 15;21(12):2870-9. doi: 10.1158/1078-0432.CCR-14-2290. Epub 2015 Mar 16.

4.

Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining.

Bergs JW, Krawczyk PM, Borovski T, ten Cate R, Rodermond HM, Stap J, Medema JP, Haveman J, Essers J, van Bree C, Stalpers LJ, Kanaar R, Aten JA, Franken NA.

DNA Repair (Amst). 2013 Jan 1;12(1):38-45. doi: 10.1016/j.dnarep.2012.10.008. Epub 2012 Dec 11.

PMID:
23237939
5.

Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme.

Borovski T, Beke P, van Tellingen O, Rodermond HM, Verhoeff JJ, Lascano V, Daalhuisen JB, Medema JP, Sprick MR.

Oncogene. 2013 Mar 21;32(12):1539-48. doi: 10.1038/onc.2012.172. Epub 2012 May 21.

PMID:
22614016
6.

Chromatin mobility is increased at sites of DNA double-strand breaks.

Krawczyk PM, Borovski T, Stap J, Cijsouw T, ten Cate R, Medema JP, Kanaar R, Franken NA, Aten JA.

J Cell Sci. 2012 May 1;125(Pt 9):2127-33. doi: 10.1242/jcs.089847. Epub 2012 Feb 10.

7.

Cancer stem cell niche: the place to be.

Borovski T, De Sousa E Melo F, Vermeulen L, Medema JP.

Cancer Res. 2011 Feb 1;71(3):634-9. doi: 10.1158/0008-5472.CAN-10-3220. Epub 2011 Jan 25. Review.

8.

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.

Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP.

Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25.

PMID:
20418870
9.

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

Sottoriva A, Verhoeff JJ, Borovski T, McWeeney SK, Naumov L, Medema JP, Sloot PM, Vermeulen L.

Cancer Res. 2010 Jan 1;70(1):46-56. doi: 10.1158/0008-5472.CAN-09-3663.

10.

Tumor microvasculature supports proliferation and expansion of glioma-propagating cells.

Borovski T, Verhoeff JJ, ten Cate R, Cameron K, de Vries NA, van Tellingen O, Richel DJ, van Furth WR, Medema JP, Sprick MR.

Int J Cancer. 2009 Sep 1;125(5):1222-30. doi: 10.1002/ijc.24408.

11.

One renegade cancer stem cell?

Borovski T, Vermeulen L, Sprick MR, Medema JP.

Cell Cycle. 2009 Mar 15;8(6):803-8. Epub 2009 Mar 26.

PMID:
19221496

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