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Items: 1 to 50 of 72

1.

Quantification of Opioids in Urine Using an Aptamer-Based Free-Solution Assay.

Kammer MN, Kussrow A, Gandhi I, Drabek R, Batchelor RH, Jackson GW, Bornhop DJ.

Anal Chem. 2019 Aug 20;91(16):10582-10588. doi: 10.1021/acs.analchem.9b01638. Epub 2019 Jul 31.

PMID:
31314489
2.

Compensated Interferometry Measures of CYFRA 21-1 Improve Diagnosis of Lung Cancer.

Kammer MN, Kussrow AK, Webster RL, Chen H, Hoeksema M, Christenson R, Massion PP, Bornhop DJ.

ACS Comb Sci. 2019 Jun 10;21(6):465-472. doi: 10.1021/acscombsci.9b00022. Epub 2019 May 10.

PMID:
31022347
3.

Rapid quantification of two chemical nerve agent metabolites in serum.

Kammer M, Kussrow A, Carter MD, Isenberg SL, Johnson RC, Batchelor RH, Jackson GW, Bornhop DJ.

Biosens Bioelectron. 2019 Apr 15;131:119-127. doi: 10.1016/j.bios.2019.01.056. Epub 2019 Jan 31.

4.

Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry.

Mizuno H, Kihara Y, Kussrow A, Chen A, Ray M, Rivera R, Bornhop DJ, Chun J.

J Lipid Res. 2019 Jan;60(1):212-217. doi: 10.1194/jlr.D089938. Epub 2018 Nov 21.

PMID:
30463988
5.

A Highly Compensated Interferometer for Biochemical Analysis.

Kammer MN, Kussrow AK, Olmsted IR, Bornhop DJ.

ACS Sens. 2018 Aug 24;3(8):1546-1552. doi: 10.1021/acssensors.8b00361. Epub 2018 Jul 25.

PMID:
29984991
6.

Longitudinal pixel averaging for improved compensation in backscattering interferometry.

Kammer MN, Kussrow AK, Bornhop DJ.

Opt Lett. 2018 Feb 1;43(3):482-485. doi: 10.1364/OL.43.000482.

PMID:
29400820
7.

Metallo-β-lactamase Domain-Containing Protein 1 (MBLAC1) Is a Specific, High-Affinity Target for the Glutamate Transporter Inducer Ceftriaxone.

Retzlaff CL, Kussrow A, Schorkopf T, Saetear P, Bornhop DJ, Hardaway JA, Sturgeon SM, Wright J, Blakely RD.

ACS Chem Neurosci. 2017 Oct 18;8(10):2132-2138. doi: 10.1021/acschemneuro.7b00232. Epub 2017 Aug 14.

PMID:
28783953
8.

Taylor Dispersion Analysis of Polysaccharides Using Backscattering Interferometry.

Saetear P, Chamieh J, Kammer MN, Manuel TJ, Biron JP, Bornhop DJ, Cottet H.

Anal Chem. 2017 Jun 20;89(12):6710-6718. doi: 10.1021/acs.analchem.7b00946. Epub 2017 Jun 7.

PMID:
28528548
9.
10.

Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.

Wang M, Kussrow AK, Ocana MF, Chabot JR, Lepsy CS, Bornhop DJ, O'Hara DM.

Br J Pharmacol. 2017 Jan;174(1):70-81. doi: 10.1111/bph.13654. Epub 2016 Nov 30.

11.

Reply to Varma: Elucidation of the signal origin for label-free, free-solution interactions.

Bornhop DJ, Kammer MN, Kussrow A, Flowers RA 2nd.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4931-2. doi: 10.1073/pnas.1609553113. Epub 2016 Jul 26. No abstract available.

12.

Origin and prediction of free-solution interaction studies performed label-free.

Bornhop DJ, Kammer MN, Kussrow A, Flowers RA 2nd, Meiler J.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1595-604. doi: 10.1073/pnas.1515706113. Epub 2016 Mar 9.

13.

Quantification of Plasmodium-host protein interactions on intact, unmodified erythrocytes by back-scattering interferometry.

Saetear P, Perrin AJ, Bartholdson SJ, Wanaguru M, Kussrow A, Bornhop DJ, Wright GJ.

Malar J. 2015 Feb 21;14:88. doi: 10.1186/s12936-015-0553-2.

14.

New tools for the quantitative assessment of prodrug delivery and neurotoxicity.

Samuelson LE, Scherer RL, VanSaun MN, Fan KH, Dozier EA, Carter KJ, Koyama T, Shyr Y, Aschner M, Stanwood GD, Bornhop DJ, Matrisian LM, McIntyre JO.

Neurotoxicology. 2015 Mar;47:88-98. doi: 10.1016/j.neuro.2015.02.005. Epub 2015 Feb 27.

15.

Characterizing aptamer small molecule interactions with backscattering interferometry.

Kammer MN, Olmsted IR, Kussrow AK, Morris MJ, Jackson GW, Bornhop DJ.

Analyst. 2014 Nov 21;139(22):5879-84. doi: 10.1039/c4an01227e.

PMID:
25229067
16.

Toward rapid, high-sensitivity, volume-constrained biomarker quantification and validation using backscattering interferometry.

Olmsted IR, Hassanein M, Kussrow A, Hoeksema M, Li M, Massion PP, Bornhop DJ.

Anal Chem. 2014 Aug 5;86(15):7566-74. doi: 10.1021/ac501355q. Epub 2014 Jul 7.

17.

Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4.

Guyon A, Kussrow A, Olmsted IR, Sandoz G, Bornhop DJ, Nahon JL.

J Neurosci. 2013 Jul 10;33(28):11643-54. doi: 10.1523/JNEUROSCI.6070-11.2013.

18.

Synthesis and in vitro efficacy of MMP9-activated NanoDendrons.

Samuelson LE, Scherer RL, Matrisian LM, McIntyre JO, Bornhop DJ.

Mol Pharm. 2013 Aug 5;10(8):3164-74. doi: 10.1021/mp4002206. Epub 2013 Jun 24.

19.

The effect of hybridization-induced secondary structure alterations on RNA detection using backscattering interferometry.

Adams NM, Olmsted IR, Haselton FR, Bornhop DJ, Wright DW.

Nucleic Acids Res. 2013 May;41(9):e103. doi: 10.1093/nar/gkt165. Epub 2013 Mar 21.

20.

Comparison of free-solution and surface-immobilized molecular interactions using a single platform.

Olmsted IR, Kussrow A, Bornhop DJ.

Anal Chem. 2012 Dec 18;84(24):10817-22. doi: 10.1021/ac302933h. Epub 2012 Dec 3.

PMID:
23173653
21.

Back-scattering interferometry: an ultrasensitive method for the unperturbed detection of acetylcholinesterase-inhibitor interactions.

Haddad GL, Young SC, Heindel ND, Bornhop DJ, Flowers RA 2nd.

Angew Chem Int Ed Engl. 2012 Oct 29;51(44):11126-30. doi: 10.1002/anie.201203640. Epub 2012 Oct 4.

22.

Recent advances in receptor-targeted fluorescent probes for in vivo cancer imaging.

Bai M, Bornhop DJ.

Curr Med Chem. 2012;19(28):4742-58. Review.

PMID:
22873663
23.

Preclinical molecular imaging of the translocator protein (TSPO) in a metastases model based on breast cancer xenografts propagated in the murine brain.

Wyatt SK, Manning HC, Bai M, Ehtesham M, Mapara KY, Thompson RC, Bornhop DJ.

Curr Mol Med. 2012 May;12(4):458-66.

24.

Interferometric methods for label-free molecular interaction studies.

Kussrow A, Enders CS, Bornhop DJ.

Anal Chem. 2012 Jan 17;84(2):779-92. doi: 10.1021/ac202812h. Epub 2011 Nov 7. Review. No abstract available.

25.

Measurement of aptamer-protein interactions with back-scattering interferometry.

Olmsted IR, Xiao Y, Cho M, Csordas AT, Sheehan JH, Meiler J, Soh HT, Bornhop DJ.

Anal Chem. 2011 Dec 1;83(23):8867-70. doi: 10.1021/ac202823m. Epub 2011 Nov 8.

PMID:
22032342
26.

Evolution and protein packaging of small-molecule RNA aptamers.

Lau JL, Baksh MM, Fiedler JD, Brown SD, Kussrow A, Bornhop DJ, Ordoukhanian P, Finn MG.

ACS Nano. 2011 Oct 25;5(10):7722-9. doi: 10.1021/nn2006927. Epub 2011 Sep 7.

27.

NIR-mbc94, a fluorescent ligand that binds to endogenous CB(2) receptors and is amenable to high-throughput screening.

Sexton M, Woodruff G, Horne EA, Lin YH, Muccioli GG, Bai M, Stern E, Bornhop DJ, Stella N.

Chem Biol. 2011 May 27;18(5):563-8. doi: 10.1016/j.chembiol.2011.02.016.

28.

Histone demethylase LSD1 is a folate-binding protein.

Luka Z, Moss F, Loukachevitch LV, Bornhop DJ, Wagner C.

Biochemistry. 2011 May 31;50(21):4750-6. doi: 10.1021/bi200247b. Epub 2011 May 5.

29.

Backscattering interferometry: an alternative approach for the study of hydrogen bonding interactions in organic solvents.

Pesciotta EN, Bornhop DJ, Flowers RA 2nd.

Org Lett. 2011 May 20;13(10):2654-7. doi: 10.1021/ol200757a. Epub 2011 Apr 21.

PMID:
21510617
30.

Label-free quantification of membrane-ligand interactions using backscattering interferometry.

Baksh MM, Kussrow AK, Mileni M, Finn MG, Bornhop DJ.

Nat Biotechnol. 2011 Apr;29(4):357-60. doi: 10.1038/nbt.1790. Epub 2011 Mar 13.

31.

Universal sensing by transduction of antibody binding with backscattering interferometry.

Kussrow A, Baksh MM, Bornhop DJ, Finn MG.

Chembiochem. 2011 Feb 11;12(3):367-70. doi: 10.1002/cbic.201000671. Epub 2010 Dec 29. No abstract available.

32.

Back-scattering interferometry: a versatile platform for the study of free-solution versus surface-immobilized hybridization.

Pesciotta EN, Bornhop DJ, Flowers RA 2nd.

Chem Asian J. 2011 Jan 3;6(1):70-3. doi: 10.1002/asia.201000614. No abstract available.

PMID:
21082726
33.

The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease.

Kussrow A, Enders CS, Castro AR, Cox DL, Ballard RC, Bornhop DJ.

Analyst. 2010 Jul;135(7):1535-7. doi: 10.1039/c0an00098a. Epub 2010 Apr 22.

34.

Molecular imaging of the translocator protein (TSPO) in a pre-clinical model of breast cancer.

Wyatt SK, Manning HC, Bai M, Bailey SN, Gallant P, Ma G, McIntosh L, Bornhop DJ.

Mol Imaging Biol. 2010 Jun;12(3):349-58. doi: 10.1007/s11307-009-0270-8. Epub 2009 Dec 1.

35.

TSPO targeted dendrimer imaging agent: synthesis, characterization, and cellular internalization.

Samuelson LE, Dukes MJ, Hunt CR, Casey JD, Bornhop DJ.

Bioconjug Chem. 2009 Nov;20(11):2082-9. doi: 10.1021/bc9002053.

36.

Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scattering interferometry.

Kussrow A, Kaltgrad E, Wolfenden ML, Cloninger MJ, Finn MG, Bornhop DJ.

Anal Chem. 2009 Jun 15;81(12):4889-97. doi: 10.1021/ac900569c.

37.

Free-solution label-free detection of alpha-crystallin chaperone interactions by back-scattering interferometry.

Latham JC, Stein RA, Bornhop DJ, Mchaourab HS.

Anal Chem. 2009 Mar 1;81(5):1865-71. doi: 10.1021/ac802327h.

38.

Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.

Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, Rothenberg ML, Bornhop DJ, Gore JC, Coffey RJ.

Clin Cancer Res. 2008 Nov 15;14(22):7413-22. doi: 10.1158/1078-0432.CCR-08-0239.

39.

MBC94, a conjugable ligand for cannabinoid CB 2 receptor imaging.

Bai M, Sexton M, Stella N, Bornhop DJ.

Bioconjug Chem. 2008 May;19(5):988-92. doi: 10.1021/bc700419e. Epub 2008 Apr 30.

40.

Role of the antenna in tissue selective probes built of lanthanide-organic chelates.

Hess BA Jr, Kedziorski A, Smentek L, Bornhop DJ.

J Phys Chem A. 2008 Mar 20;112(11):2397-407. doi: 10.1021/jp075736y. Epub 2008 Feb 26.

PMID:
18298101
41.

A novel functional translocator protein ligand for cancer imaging.

Bai M, Rone MB, Papadopoulos V, Bornhop DJ.

Bioconjug Chem. 2007 Nov-Dec;18(6):2018-23. Epub 2007 Nov 3.

PMID:
17979225
42.

Free-solution, label-free molecular interactions studied by back-scattering interferometry.

Bornhop DJ, Latham JC, Kussrow A, Markov DA, Jones RD, Sørensen HS.

Science. 2007 Sep 21;317(5845):1732-6.

43.

A novel conjugable translocator protein ligand labeled with a fluorescence dye for in vitro imaging.

Bai M, Wyatt SK, Han Z, Papadopoulos V, Bornhop DJ.

Bioconjug Chem. 2007 Jul-Aug;18(4):1118-22. Epub 2007 Jun 7.

PMID:
17552492
44.

Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation.

Deane NG, Manning HC, Foutch AC, Washington MK, Aronow BJ, Bornhop DJ, Coffey RJ.

Mol Cancer Res. 2007 Apr;5(4):341-9. Erratum in: Mol Cancer Res. 2007 May;5(5):521. Aronow, Bruce A [corrected to Aronow, Bruce J].

45.

A peripheral benzodiazepine receptor targeted agent for in vitro imaging and screening.

Manning HC, Smith SM, Sexton M, Haviland S, Bai M, Cederquist K, Stella N, Bornhop DJ.

Bioconjug Chem. 2006 May-Jun;17(3):735-40.

PMID:
16704212
46.

Density-functional theory structures of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid complexes for ions across the lanthanide series.

Smentek L, Andes Hess B, Cross JP, Charles Manning H, Bornhop DJ.

J Chem Phys. 2005 Dec 22;123(24):244302.

PMID:
16396532
47.

Photobiotin surface chemistry improves label-free interferometric sensing of biochemical interactions.

Latham JC, Markov DA, Sørensen HS, Bornhop DJ.

Angew Chem Int Ed Engl. 2006 Jan 30;45(6):955-8. No abstract available.

PMID:
16385602
49.

Label-free molecular interaction determinations with nanoscale interferometry.

Markov DA, Swinney K, Bornhop DJ.

J Am Chem Soc. 2004 Dec 22;126(50):16659-64.

PMID:
15600372
50.

Noninvasive fluid flow measurements in microfluidic channels with backscatter interferometry.

Markov DA, Dotson S, Wood S, Bornhop DJ.

Electrophoresis. 2004 Nov;25(21-22):3805-9.

PMID:
15565690

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