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Items: 37

1.

The RNA exosome contributes to gene expression regulation during stem cell differentiation.

Lloret-Llinares M, Karadoulama E, Chen Y, Wojenski LA, Villafano GJ, Bornholdt J, Andersson R, Core L, Sandelin A, Jensen TH.

Nucleic Acids Res. 2018 Sep 13. doi: 10.1093/nar/gky817. [Epub ahead of print]

PMID:
30212902
2.

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.

Boyd M, Thodberg M, Vitezic M, Bornholdt J, Vitting-Seerup K, Chen Y, Coskun M, Li Y, Lo BZS, Klausen P, Jan Schweiger P, Pedersen AG, Rapin N, Skovgaard K, Dahlgaard K, Andersson R, Terkelsen TB, Lilje B, Troelsen JT, Petersen AM, Jensen KB, Gögenur I, Thielsen P, Seidelin JB, Nielsen OH, Bjerrum JT, Sandelin A.

Nat Commun. 2018 Apr 25;9(1):1661. doi: 10.1038/s41467-018-03766-z.

3.

A new class of genic nuclear RNA species in Arabidopsis.

van Wonterghem M, Thieffry A, Boyd M, Bornholdt J, Brodersen P.

FEBS Lett. 2018 Feb;592(4):631-643. doi: 10.1002/1873-3468.12981. Epub 2018 Feb 6.

PMID:
29355922
4.

Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels.

Chen Y, Salem M, Boyd M, Bornholdt J, Li Y, Coskun M, Seidelin JB, Sandelin A, Nielsen OH.

NPJ Genom Med. 2017 Feb 8;2:3. doi: 10.1038/s41525-016-0001-4. eCollection 2017.

5.

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo.

Bornholdt J, Saber AT, Lilje B, Boyd M, Jørgensen M, Chen Y, Vitezic M, Jacobsen NR, Poulsen SS, Berthing T, Bressendorff S, Vitting-Seerup K, Andersson R, Hougaard KS, Yauk CL, Halappanavar S, Wallin H, Vogel U, Sandelin A.

ACS Nano. 2017 Apr 25;11(4):3597-3613. doi: 10.1021/acsnano.6b07533. Epub 2017 Mar 31.

PMID:
28345861
6.

On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase.

Ienasescu H, Li K, Andersson R, Vitezic M, Rennie S, Chen Y, Vitting-Seerup K, Lagoni E, Boyd M, Bornholdt J, de Hoon MJ, Kawaji H, Lassmann T; FANTOM Consortium, Hayashizaki Y, Forrest AR, Carninci P, Sandelin A.

Database (Oxford). 2016 Dec 26;2016. pii: baw144. doi: 10.1093/database/baw144. Print 2016.

7.

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.

Rydén M, Hrydziuszko O, Mileti E, Raman A, Bornholdt J, Boyd M, Toft E, Qvist V, Näslund E, Thorell A, Andersson DP, Dahlman I, Gao H, Sandelin A, Daub CO, Arner P.

Cell Rep. 2016 Aug 30;16(9):2317-26. doi: 10.1016/j.celrep.2016.07.070. Epub 2016 Aug 18.

8.

Regulating retrotransposon activity through the use of alternative transcription start sites.

Persson J, Steglich B, Smialowska A, Boyd M, Bornholdt J, Andersson R, Schurra C, Arcangioli B, Sandelin A, Nielsen O, Ekwall K.

EMBO Rep. 2016 May;17(5):753-68. doi: 10.15252/embr.201541866. Epub 2016 Feb 22.

9.

Nuclear stability and transcriptional directionality separate functionally distinct RNA species.

Andersson R, Refsing Andersen P, Valen E, Core LJ, Bornholdt J, Boyd M, Heick Jensen T, Sandelin A.

Nat Commun. 2014 Nov 12;5:5336. doi: 10.1038/ncomms6336.

PMID:
25387874
10.

Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.

Boyd M, Coskun M, Lilje B, Andersson R, Hoof I, Bornholdt J, Dahlgaard K, Olsen J, Vitezic M, Bjerrum JT, Seidelin JB, Nielsen OH, Troelsen JT, Sandelin A.

DNA Res. 2014 Dec;21(6):569-83. doi: 10.1093/dnares/dsu022. Epub 2014 Jul 2.

11.

An atlas of active enhancers across human cell types and tissues.

Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E, Valen E, Li K, Schwarzfischer L, Glatz D, Raithel J, Lilje B, Rapin N, Bagger FO, Jørgensen M, Andersen PR, Bertin N, Rackham O, Burroughs AM, Baillie JK, Ishizu Y, Shimizu Y, Furuhata E, Maeda S, Negishi Y, Mungall CJ, Meehan TF, Lassmann T, Itoh M, Kawaji H, Kondo N, Kawai J, Lennartsson A, Daub CO, Heutink P, Hume DA, Jensen TH, Suzuki H, Hayashizaki Y, Müller F, Forrest ARR, Carninci P, Rehli M, Sandelin A.

Nature. 2014 Mar 27;507(7493):455-461. doi: 10.1038/nature12787.

12.

Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair.

Vestentoft PS, Jelnes P, Andersen JB, Tran TA, Jørgensen T, Rasmussen M, Bornholdt J, Grøvdal LM, Jensen CH, Vogel LK, Thorgeirsson SS, Bisgaard HC.

Fibrogenesis Tissue Repair. 2013 Dec 20;6(1):21. doi: 10.1186/1755-1536-6-21.

13.

Detection of active matriptase using a biotinylated chloromethyl ketone peptide.

Godiksen S, Soendergaard C, Friis S, Jensen JK, Bornholdt J, Sales KU, Huang M, Bugge TH, Vogel LK.

PLoS One. 2013 Oct 18;8(10):e77146. doi: 10.1371/journal.pone.0077146. eCollection 2013.

14.

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality.

Ntini E, Järvelin AI, Bornholdt J, Chen Y, Boyd M, Jørgensen M, Andersson R, Hoof I, Schein A, Andersen PR, Andersen PK, Preker P, Valen E, Zhao X, Pelechano V, Steinmetz LM, Sandelin A, Jensen TH.

Nat Struct Mol Biol. 2013 Aug;20(8):923-8. doi: 10.1038/nsmb.2640. Epub 2013 Jul 14.

PMID:
23851456
15.

Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase.

Larsen BR, Steffensen SD, Nielsen NV, Friis S, Godiksen S, Bornholdt J, Soendergaard C, Nonboe AW, Andersen MN, Poulsen SS, Szabo R, Bugge TH, Lin CY, Skovbjerg H, Jensen JK, Vogel LK.

Exp Cell Res. 2013 Apr 1;319(6):918-29. doi: 10.1016/j.yexcr.2013.01.008. Epub 2013 Jan 16.

16.

The level of claudin-7 is reduced as an early event in colorectal carcinogenesis.

Bornholdt J, Friis S, Godiksen S, Poulsen SS, Santoni-Rugiu E, Bisgaard HC, Lothe IM, Ikdahl T, Tveit KM, Johnson E, Kure EH, Vogel LK.

BMC Cancer. 2011 Feb 10;11:65. doi: 10.1186/1471-2407-11-65.

17.

Expression profile of the N-myc Downstream Regulated Gene 2 (NDRG2) in human cancers with focus on breast cancer.

Lorentzen A, Lewinsky RH, Bornholdt J, Vogel LK, Mitchelmore C.

BMC Cancer. 2011 Jan 12;11:14. doi: 10.1186/1471-2407-11-14.

18.

Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase.

Friis S, Godiksen S, Bornholdt J, Selzer-Plon J, Rasmussen HB, Bugge TH, Lin CY, Vogel LK.

J Biol Chem. 2011 Feb 18;286(7):5793-802. doi: 10.1074/jbc.M110.186874. Epub 2010 Dec 10.

19.

Synthesis of enantiopure 3-substituted morpholines.

Bornholdt J, Felding J, Kristensen JL.

J Org Chem. 2010 Nov 5;75(21):7454-7. doi: 10.1021/jo101339g.

PMID:
20879782
20.

Ring opening of pymisyl-protected aziridines with organocuprates.

Bornholdt J, Felding J, Clausen RP, Kristensen JL.

Chemistry. 2010 Nov 2;16(41):12474-80. doi: 10.1002/chem.201001026.

PMID:
20839183
21.

Profile of TP53 gene mutations in sinonasal cancer.

Holmila R, Bornholdt J, Suitiala T, Cyr D, Dictor M, Steiniche T, Wolff H, Wallin H, Luce D, Husgafvel-Pursiainen K.

Mutat Res. 2010 Apr 1;686(1-2):9-14. doi: 10.1016/j.mrfmmm.2009.12.003. Epub 2009 Dec 16.

PMID:
20025891
22.

Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer.

Holmila R, Bornholdt J, Heikkilä P, Suitiala T, Févotte J, Cyr D, Hansen J, Snellman SM, Dictor M, Steiniche T, Schlünssen V, Schneider T, Pukkala E, Savolainen K, Wolff H, Wallin H, Luce D, Husgafvel-Pursiainen K.

Int J Cancer. 2010 Aug 1;127(3):578-88. doi: 10.1002/ijc.25064.

23.

Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.

Selzer-Plon J, Bornholdt J, Friis S, Bisgaard HC, Lothe IM, Tveit KM, Kure EH, Vogel U, Vogel LK.

BMC Cancer. 2009 Jun 25;9:201. doi: 10.1186/1471-2407-9-201.

24.

Lack of acute phase response in the livers of mice exposed to diesel exhaust particles or carbon black by inhalation.

Saber AT, Halappanavar S, Folkmann JK, Bornholdt J, Boisen AM, Møller P, Williams A, Yauk C, Vogel U, Loft S, Wallin H.

Part Fibre Toxicol. 2009 Apr 20;6:12. doi: 10.1186/1743-8977-6-12.

25.

K-ras mutations in sinonasal cancers in relation to wood dust exposure.

Bornholdt J, Hansen J, Steiniche T, Dictor M, Antonsen A, Wolff H, Schlünssen V, Holmila R, Luce D, Vogel U, Husgafvel-Pursiainen K, Wallin H.

BMC Cancer. 2008 Feb 20;8:53. doi: 10.1186/1471-2407-8-53.

26.

COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure.

Holmila R, Cyr D, Luce D, Heikkilä P, Dictor M, Steiniche T, Stjernvall T, Bornholdt J, Wallin H, Wolff H, Husgafvel-Pursiainen K.

Int J Cancer. 2008 May 1;122(9):2154-9. doi: 10.1002/ijc.23360.

27.

Inflammatory response and genotoxicity of seven wood dusts in the human epithelial cell line A549.

Bornholdt J, Saber AT, Sharma AK, Savolainen K, Vogel U, Wallin H.

Mutat Res. 2007 Aug 15;632(1-2):78-88. Epub 2007 May 21.

PMID:
17590384
28.

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor.

Saber AT, Jacobsen NR, Bornholdt J, Kjaer SL, Dybdahl M, Risom L, Loft S, Vogel U, Wallin H.

Part Fibre Toxicol. 2006 Feb 20;3:4.

29.

Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation.

Saber AT, Bornholdt J, Dybdahl M, Sharma AK, Loft S, Vogel U, Wallin H.

Arch Toxicol. 2005 Mar;79(3):177-82. Epub 2004 Nov 11.

PMID:
15798890
30.

Sucrose and IQ induced mutations in rat colon by independent mechanism.

Hansen M, Hald MT, Autrup H, Vogel U, Bornholdt J, Møller P, Mølck AM, Lindecrona R, Poulsen HE, Wallin H, Loft S, Dragsted LO.

Mutat Res. 2004 Oct 4;554(1-2):279-86.

PMID:
15450425
31.

Inflammatory and genotoxic effects of diesel particles in vitro and in vivo.

Dybdahl M, Risom L, Bornholdt J, Autrup H, Loft S, Wallin H.

Mutat Res. 2004 Aug 8;562(1-2):119-31.

PMID:
15279835
32.

Cell-specific oxidative DNA damage induced by estrogen in rat testicular cells in vitro.

Wellejus A, Bornholdt J, Vogel UB, Risom L, Wiger R, Loft S.

Toxicol Lett. 2004 May 2;150(3):317-23.

PMID:
15110083
33.

Dietary elevated sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big Blue rats.

Risom L, Møller P, Hansen M, Autrup H, Bornholdt J, Vogel U, Wallin H, Poulsen HE, Dragsted LO, Loft S.

Arch Toxicol. 2003 Nov;77(11):651-6. Epub 2003 Aug 23.

PMID:
12937889
34.

DNA adduct formation and oxidative stress in colon and liver of Big Blue rats after dietary exposure to diesel particles.

Dybdahl M, Risom L, Møller P, Autrup H, Wallin H, Vogel U, Bornholdt J, Daneshvar B, Dragsted LO, Weimann A, Poulsen HE, Loft S.

Carcinogenesis. 2003 Nov;24(11):1759-66. Epub 2003 Aug 14.

PMID:
12919963
35.

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation.

Risom L, Dybdahl M, Bornholdt J, Vogel U, Wallin H, Møller P, Loft S.

Carcinogenesis. 2003 Nov;24(11):1847-52. Epub 2003 Aug 14.

PMID:
12919962
36.

Inhalation of ozone induces DNA strand breaks and inflammation in mice.

Bornholdt J, Dybdahl M, Vogel U, Hansen M, Loft S, Wallin H.

Mutat Res. 2002 Sep 26;520(1-2):63-71.

PMID:
12297145
37.

Fears of dying.

Bornholdt J.

N Z Nurs J. 1986 Apr;79(4):17-9. No abstract available.

PMID:
3459108

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