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Items: 36

1.

Pharmacological abrogation of S-phase checkpoint enhances the anti-tumor activity of gemcitabine in vivo.

Matthews DJ, Yakes FM, Chen J, Tadano M, Bornheim L, Clary DO, Tai A, Wagner JM, Miller N, Kim YD, Robertson S, Murray L, Karnitz LM.

Cell Cycle. 2007 Jan 1;6(1):104-10. Epub 2007 Jan 7.

PMID:
17245119
2.

Cannabinoid-induced alterations in brain disposition of drugs of abuse.

Reid MJ, Bornheim LM.

Biochem Pharmacol. 2001 Jun 1;61(11):1357-67.

PMID:
11331071
3.

The effects of phencyclidine pretreatment on cocaine-mediated hepatotoxicity in mice.

Reid MJ, Bornheim LM.

Toxicol Appl Pharmacol. 2001 May 1;172(3):194-202.

PMID:
11312647
4.

Effects of unsaturated side-chain analogs of tetrahydrocannabinol on cytochromes P450.

Bornheim LM.

Biochem Pharmacol. 2000 Oct 1;60(7):955-61.

PMID:
10974204
5.

The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver.

Schuetz EG, Schmid W, Schutz G, Brimer C, Yasuda K, Kamataki T, Bornheim L, Myles K, Cole TJ.

Drug Metab Dispos. 2000 Mar;28(3):268-78.

PMID:
10681370
6.

Ethynylestradiol-mediated induction of hepatic CYP3A9 in female rats: implication for cyclosporine metabolism.

J├Ąger W, Correia MA, Bornheim LM, Mahnke A, Hanstein WG, Xue L, Benet LZ.

Drug Metab Dispos. 1999 Dec;27(12):1505-11.

PMID:
10570034
7.

Identification of the heme-modified peptides from cumene hydroperoxide-inactivated cytochrome P450 3A4.

He K, Bornheim LM, Falick AM, Maltby D, Yin H, Correia MA.

Biochemistry. 1998 Dec 15;37(50):17448-57.

PMID:
9860860
9.

Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity.

Bornheim LM.

Toxicol Appl Pharmacol. 1998 May;150(1):158-65.

PMID:
9630465
10.

Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration.

Yost CS, Hampson AJ, Leonoudakis D, Koblin DD, Bornheim LM, Gray AT.

Anesth Analg. 1998 Jun;86(6):1294-300.

PMID:
9620523
11.

Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission.

Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ, Bickler PE.

J Neurochem. 1998 Feb;70(2):671-6.

13.
14.

Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor.

Hampson AJ, Hill WA, Zan-Phillips M, Makriyannis A, Leung E, Eglen RM, Bornheim LM.

Biochim Biophys Acta. 1995 Nov 16;1259(2):173-9.

PMID:
7488638
15.

A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli.

Richardson TH, Jung F, Griffin KJ, Wester M, Raucy JL, Kemper B, Bornheim LM, Hassett C, Omiecinski CJ, Johnson EF.

Arch Biochem Biophys. 1995 Oct 20;323(1):87-96.

PMID:
7487078
16.

Microsomal cytochrome P450-mediated liver and brain anandamide metabolism.

Bornheim LM, Kim KY, Chen B, Correia MA.

Biochem Pharmacol. 1995 Aug 25;50(5):677-86.

PMID:
7669071
17.

Effect of cannabidiol pretreatment on the kinetics of tetrahydrocannabinol metabolites in mouse brain.

Bornheim LM, Kim KY, Li J, Perotti BY, Benet LZ.

Drug Metab Dispos. 1995 Aug;23(8):825-31.

PMID:
7493549
18.

Induction and genetic regulation of mouse hepatic cytochrome P450 by cannabidiol.

Bornheim LM, Everhart ET, Li J, Correia MA.

Biochem Pharmacol. 1994 Jul 5;48(1):161-71.

PMID:
8043019
19.

The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism.

Bornheim LM, Kim KY, Chen B, Correia MA.

Biochem Biophys Res Commun. 1993 Dec 15;197(2):740-6.

PMID:
8267610
20.

Characterization of cannabidiol-mediated cytochrome P450 inactivation.

Bornheim LM, Everhart ET, Li J, Correia MA.

Biochem Pharmacol. 1993 Mar 24;45(6):1323-31.

PMID:
8466552
21.

Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol.

Bornheim LM, Lasker JM, Raucy JL.

Drug Metab Dispos. 1992 Mar-Apr;20(2):241-6.

PMID:
1352216
22.
24.

Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol.

Bornheim LM, Correia MA.

Mol Pharmacol. 1990 Sep;38(3):319-26.

PMID:
2402224
25.

Enantioselective S-oxygenation by flavin-containing and cytochrome P-450 monooxygenases.

Cashman JR, Olsen LD, Bornheim LM.

Chem Res Toxicol. 1990 Jul-Aug;3(4):344-9.

PMID:
2133083
26.

Purification and characterization of a mouse liver cytochrome P-450 induced by cannabidiol.

Bornheim LM, Correia MA.

Mol Pharmacol. 1989 Sep;36(3):377-83.

PMID:
2779523
27.

Effect of cannabidiol on cytochrome P-450 isozymes.

Bornheim LM, Correia MA.

Biochem Pharmacol. 1989 Sep 1;38(17):2789-94.

PMID:
2550010
28.

Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts.

Correia MA, Decker C, Sugiyama K, Caldera P, Bornheim L, Wrighton SA, Rettie AE, Trager WF.

Arch Biochem Biophys. 1987 Nov 1;258(2):436-51.

PMID:
3674884
29.

Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implications.

Bornheim LM, Underwood MC, Caldera P, Rettie AE, Trager WF, Wrighton SA, Correia MA.

Mol Pharmacol. 1987 Aug;32(1):299-308.

PMID:
3302670
31.

The influence of side chain modifications of the heme moiety on prosthetic acceptance and function of rat hepatic cytochrome P-450 and tryptophan pyrrolase.

Bornheim LM, Parish DW, Smith KM, Litman DA, Correia MA.

Arch Biochem Biophys. 1986 Apr;246(1):63-74.

PMID:
3963832
32.
33.

Functional reconstitution of rat liver cytochrome P-450 with mesohemin.

Bornheim LM, Correia MA, Smith KM.

Biochem Biophys Res Commun. 1984 May 31;121(1):95-101.

PMID:
6732820
34.

The induction of multiple forms of cytochrome P-450 by SKF 525-A.

Bornheim LM, Peters PG, Franklin MR.

Chem Biol Interact. 1983 Oct 15;47(1):45-55.

PMID:
6640785
36.

Effect of cannabidiol on cytochrome P-450 and hexobarbital sleep time.

Bornheim LM, Borys HK, Karler R.

Biochem Pharmacol. 1981 Mar 1;30(5):503-7. No abstract available.

PMID:
7225146

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