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Items: 1 to 50 of 123

1.

Response by Fotakis et al to Letter Regarding Article, "Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques".

Fotakis P, Kothari V, Bornfeldt KE, Tall AR.

Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):e33-e34. doi: 10.1161/ATVBAHA.119.313737. Epub 2020 Jan 22. No abstract available.

PMID:
31967903
2.

Correction: Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.

Guo R, Hua Y, Ren J, Bornfeldt KE, Nair S.

Cell Death Dis. 2019 Dec 5;10(12):933. doi: 10.1038/s41419-019-2113-0.

3.

TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells.

Jung HS, Shimizu-Albergine M, Shen X, Kramer F, Shao D, Vivekanandan-Giri A, Pennathur S, Tian R, Kanter JE, Bornfeldt KE.

J Lipid Res. 2020 Jan;61(1):33-44. doi: 10.1194/jlr.RA119000256. Epub 2019 Nov 13.

PMID:
31722970
4.

High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.

Vaisar T, Kanter JE, Wimberger J, Irwin AD, Gauthier J, Wolfson E, Bahnam V, Wu IH, Shah H, Keenan HA, Greenbaum CJ, King GL, Heinecke JW, Bornfeldt KE.

Diabetes Care. 2020 Jan;43(1):178-186. doi: 10.2337/dc19-0772. Epub 2019 Oct 9.

PMID:
31597668
5.

Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.

Fotakis P, Kothari V, Thomas DG, Westerterp M, Molusky MM, Altin E, Abramowicz S, Wang N, He Y, Heinecke JW, Bornfeldt KE, Tall AR.

Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):e253-e272. doi: 10.1161/ATVBAHA.119.313253. Epub 2019 Oct 3.

PMID:
31578081
6.

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.

Kanter JE, Shao B, Kramer F, Barnhart S, Shimizu-Albergine M, Vaisar T, Graham MJ, Crooke RM, Manuel CR, Haeusler RA, Mar D, Bomsztyk K, Hokanson JE, Kinney GL, Snell-Bergeon JK, Heinecke JW, Bornfeldt KE.

J Clin Invest. 2019 Jul 11;130:4165-4179. doi: 10.1172/JCI127308.

7.

Growing evidence for a role for acyl-CoA synthetase 1 in immunometabolism.

Bornfeldt KE.

J Leukoc Biol. 2019 Oct;106(4):787-790. doi: 10.1002/JLB.3CE0519-154R. Epub 2019 Jul 3.

PMID:
31269272
8.

Albuminuria, the High-Density Lipoprotein Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus.

Shao B, Zelnick LR, Wimberger J, Himmelfarb J, Brunzell J, Davidson WS, Snell-Bergeon JK, Bornfeldt KE, de Boer IH, Heinecke JW.

Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1483-1491. doi: 10.1161/ATVBAHA.119.312556. Epub 2019 May 16.

PMID:
31092010
9.

Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density Lipoprotein.

He Y, Song HD, Anantharamaiah GM, Palgunachari MN, Bornfeldt KE, Segrest JP, Heinecke JW.

Mol Cell Proteomics. 2019 May;18(5):854-864. doi: 10.1074/mcp.RA118.000878. Epub 2019 Jan 18.

PMID:
30659061
10.

Highlighting Residual Atherosclerotic Cardiovascular Disease Risk.

Matsuura Y, Kanter JE, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2019 Jan;39(1):e1-e9. doi: 10.1161/ATVBAHA.118.311999. No abstract available.

11.

Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation.

Tang J, Frey JM, Wilson CL, Moncada-Pazos A, Levet C, Freeman M, Rosenfeld ME, Stanley ER, Raines EW, Bornfeldt KE.

Mol Cell Biol. 2018 Aug 15;38(17). pii: e00103-18. doi: 10.1128/MCB.00103-18. Print 2018 Sep 1.

12.

Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.

Guo R, Hua Y, Ren J, Bornfeldt KE, Nair S.

Cell Death Dis. 2018 Jun 7;9(6):692. doi: 10.1038/s41419-018-0727-2. Erratum in: Cell Death Dis. 2019 Dec 5;10(12):933.

13.

Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome.

Wall VZ, Barnhart S, Kanter JE, Kramer F, Shimizu-Albergine M, Adhikari N, Wight TN, Hall JL, Bornfeldt KE.

JCI Insight. 2018 Jun 7;3(11). pii: 96544. doi: 10.1172/jci.insight.96544. eCollection 2018 Jun 7.

14.

Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics.

Rune I, Rolin B, Lykkesfeldt J, Nielsen DS, Krych Ł, Kanter JE, Bornfeldt KE, Kihl P, Buschard K, Josefsen K, Fels JJ, Mortensen A, Christoffersen B, Kirk RK, Hansen AK.

Sci Rep. 2018 Apr 3;8(1):5416. doi: 10.1038/s41598-018-23835-z.

15.

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.

Kanter JE, Kramer F, Barnhart S, Duggan JM, Shimizu-Albergine M, Kothari V, Chait A, Bouman SD, Hamerman JA, Hansen BF, Olsen GS, Bornfeldt KE.

Diabetes. 2018 May;67(5):946-959. doi: 10.2337/db17-0744. Epub 2018 Feb 26.

16.

High-Density Lipoprotein Function in Cardiovascular Disease and Diabetes Mellitus.

He Y, Kothari V, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):e10-e16. doi: 10.1161/ATVBAHA.117.310222. Review. No abstract available.

17.

Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor.

Basu D, Hu Y, Huggins LA, Mullick AE, Graham MJ, Wietecha T, Barnhart S, Mogul A, Pfeiffer K, Zirlik A, Fisher EA, Bornfeldt KE, Willecke F, Goldberg IJ.

Circ Res. 2018 Feb 16;122(4):560-567. doi: 10.1161/CIRCRESAHA.117.311361. Epub 2018 Jan 10.

18.

A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis.

Bornfeldt KE, Kramer F, Batorsky A, Choi J, Hudkins KL, Tontonoz P, Alpers CE, Kanter JE.

Am J Pathol. 2018 Feb;188(2):343-352. doi: 10.1016/j.ajpath.2017.10.012. Epub 2017 Dec 15.

19.

Liver Kinase B1 Links Macrophage Metabolism Sensing and Atherosclerosis.

Kothari V, Bornfeldt KE.

Circ Res. 2017 Oct 13;121(9):1024-1026. doi: 10.1161/CIRCRESAHA.117.311923. No abstract available.

20.

A Long Road Ahead for Discovering New HDL Metrics That Reflect Cardiovascular Disease Risk.

Heinecke JW, Bornfeldt KE.

J Am Coll Cardiol. 2017 Jul 11;70(2):179-181. doi: 10.1016/j.jacc.2017.05.038. No abstract available.

21.

Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages.

Wall VZ, Barnhart S, Kramer F, Kanter JE, Vivekanandan-Giri A, Pennathur S, Bolego C, Ellis JM, Gijón MA, Wolfgang MJ, Bornfeldt KE.

J Lipid Res. 2017 Jun;58(6):1174-1185. doi: 10.1194/jlr.M076489. Epub 2017 Apr 17.

22.

SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP.

Shimizu-Albergine M, Van Yserloo B, Golkowski MG, Ong SE, Beavo JA, Bornfeldt KE.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5685-93. doi: 10.1073/pnas.1611424113. Epub 2016 Sep 6.

23.

Does Elevated Glucose Promote Atherosclerosis? Pros and Cons.

Bornfeldt KE.

Circ Res. 2016 Jul 8;119(2):190-3. doi: 10.1161/CIRCRESAHA.116.308873. Review. No abstract available.

24.

Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes.

Vallerie SN, Kramer F, Barnhart S, Kanter JE, Breyer RM, Andreasson KI, Bornfeldt KE.

PLoS One. 2016 Jun 28;11(6):e0158316. doi: 10.1371/journal.pone.0158316. eCollection 2016.

25.

Impact of Diabetes Mellitus.

Kanter JE, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1049-53. doi: 10.1161/ATVBAHA.116.307302. Review. No abstract available.

26.

Macrophage Phenotype and Function in Different Stages of Atherosclerosis.

Tabas I, Bornfeldt KE.

Circ Res. 2016 Feb 19;118(4):653-67. doi: 10.1161/CIRCRESAHA.115.306256. Review.

27.

Atherosclerosis: Successes, Surprises, and Future Challenges.

Libby P, Bornfeldt KE, Tall AR.

Circ Res. 2016 Feb 19;118(4):531-4. doi: 10.1161/CIRCRESAHA.116.308334. No abstract available.

28.

Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice.

Rune I, Rolin B, Larsen C, Nielsen DS, Kanter JE, Bornfeldt KE, Lykkesfeldt J, Buschard K, Kirk RK, Christoffersen B, Fels JJ, Josefsen K, Kihl P, Hansen AK.

PLoS One. 2016 Jan 22;11(1):e0146439. doi: 10.1371/journal.pone.0146439. eCollection 2016.

29.

Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis.

Manichaikul A, Wang XQ, Zhao W, Wojczynski MK, Siebenthall K, Stamatoyannopoulos JA, Saleheen D, Borecki IB, Reilly MP, Rich SS, Bornfeldt KE.

J Lipid Res. 2016 Mar;57(3):433-42. doi: 10.1194/jlr.M064592. Epub 2015 Dec 28.

30.

Metabolic Flexibility and Dysfunction in Cardiovascular Cells.

Vallerie SN, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):e37-42. doi: 10.1161/ATVBAHA.115.306226. Review. No abstract available.

31.

Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture.

Bornfeldt KE.

Diabetes. 2015 Aug;64(8):2689-97. doi: 10.2337/db14-1963.

32.

Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice.

Willecke F, Yuan C, Oka K, Chan L, Hu Y, Barnhart S, Bornfeldt KE, Goldberg IJ, Fisher EA.

PLoS One. 2015 Jun 5;10(6):e0128996. doi: 10.1371/journal.pone.0128996. eCollection 2015.

33.

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.

Pamir N, Liu NC, Irwin A, Becker L, Peng Y, Ronsein GE, Bornfeldt KE, Duffield JS, Heinecke JW.

J Biol Chem. 2015 Jun 5;290(23):14656-67. doi: 10.1074/jbc.M115.645820. Epub 2015 Apr 30.

34.

GPIHBP1: two get tangled.

Vallerie SN, Bornfeldt KE.

Circ Res. 2015 Feb 13;116(4):560-2. doi: 10.1161/CIRCRESAHA.115.305819. No abstract available.

35.

Arterial smooth muscle.

Wall VZ, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2175-9. doi: 10.1161/ATVBAHA.114.304441. No abstract available.

36.

Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase.

Lee JT, Pamir N, Liu NC, Kirk EA, Averill MM, Becker L, Larson I, Hagman DK, Foster-Schubert KE, van Yserloo B, Bornfeldt KE, LeBoeuf RC, Kratz M, Heinecke JW.

Endocrinology. 2014 Sep;155(9):3409-20. doi: 10.1210/en.2014-1037. Epub 2014 Jun 10.

37.

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.

Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, Tall AR, Goldberg IJ, Murphy AJ.

Cell Metab. 2014 May 6;19(5):821-35. doi: 10.1016/j.cmet.2014.03.029.

38.

Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.

Nishizawa T, Kanter JE, Kramer F, Barnhart S, Shen X, Vivekanandan-Giri A, Wall VZ, Kowitz J, Devaraj S, O'Brien KD, Pennathur S, Tang J, Miyaoka RS, Raines EW, Bornfeldt KE.

Cell Rep. 2014 Apr 24;7(2):356-365. doi: 10.1016/j.celrep.2014.03.028. Epub 2014 Apr 13.

39.

2013 Russell Ross memorial lecture in vascular biology: cellular and molecular mechanisms of diabetes mellitus-accelerated atherosclerosis.

Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):705-14. doi: 10.1161/ATVBAHA.113.301928.

40.

The p75 neurotrophin receptor is required for the major loss of sympathetic nerves from islets under autoimmune attack.

Taborsky GJ Jr, Mei Q, Bornfeldt KE, Hackney DJ, Mundinger TO.

Diabetes. 2014 Jul;63(7):2369-79. doi: 10.2337/db13-0778. Epub 2014 Mar 7.

41.

Lipids and the endothelium: bidirectional interactions.

Goldberg IJ, Bornfeldt KE.

Curr Atheroscler Rep. 2013 Nov;15(11):365. doi: 10.1007/s11883-013-0365-1. Review.

42.

Evidence stacks up that endothelial insulin resistance is a culprit in atherosclerosis.

Kanter JE, Bornfeldt KE.

Circ Res. 2013 Aug 2;113(4):352-4. doi: 10.1161/CIRCRESAHA.113.301998. No abstract available.

43.

Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.

Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MS, Vivekanandan-Giri A, Pennathur S, Albert CJ, Ford DA, Davis RJ, Bornfeldt KE.

J Biol Chem. 2013 Apr 5;288(14):9957-70. doi: 10.1074/jbc.M113.458372. Epub 2013 Feb 20.

44.

VASP increases hepatic fatty acid oxidation by activating AMPK in mice.

Tateya S, Rizzo-De Leon N, Handa P, Cheng AM, Morgan-Stevenson V, Ogimoto K, Kanter JE, Bornfeldt KE, Daum G, Clowes AW, Chait A, Kim F.

Diabetes. 2013 Jun;62(6):1913-22. doi: 10.2337/db12-0325. Epub 2013 Jan 24.

45.

Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment.

Li X, Gonzalez O, Shen X, Barnhart S, Kramer F, Kanter JE, Vivekanandan-Giri A, Tsuchiya K, Handa P, Pennathur S, Kim F, Coleman RA, Schaffer JE, Bornfeldt KE.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):232-40. doi: 10.1161/ATVBAHA.112.252239. Epub 2012 Dec 13.

46.

Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators.

Kanter JE, Bornfeldt KE.

Trends Endocrinol Metab. 2013 Mar;24(3):137-44. doi: 10.1016/j.tem.2012.10.002. Epub 2012 Nov 13. Review.

47.

Microvascular management of systemic insulin sensitivity.

Rubinow KB, Bornfeldt KE.

Circ Res. 2012 Sep 28;111(8):951-3. No abstract available.

48.

Novel insights into the role of S100A8/A9 in skin biology.

Kerkhoff C, Voss A, Scholzen TE, Averill MM, Zänker KS, Bornfeldt KE.

Exp Dermatol. 2012 Nov;21(11):822-6. doi: 10.1111/j.1600-0625.2012.01571.x. Epub 2012 Aug 9. Review.

49.

Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships.

Pathare PP, Lin A, Bornfeldt KE, Taubert S, Van Gilst MR.

PLoS Genet. 2012;8(4):e1002645. doi: 10.1371/journal.pgen.1002645. Epub 2012 Apr 12.

50.

Unique proteomic signatures distinguish macrophages and dendritic cells.

Becker L, Liu NC, Averill MM, Yuan W, Pamir N, Peng Y, Irwin AD, Fu X, Bornfeldt KE, Heinecke JW.

PLoS One. 2012;7(3):e33297. doi: 10.1371/journal.pone.0033297. Epub 2012 Mar 12.

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