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Items: 48

1.

Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic AKI.

Wang Z, Salih E, Igwebuike C, Mulhern R, Bonegio RG, Havasi A, Borkan SC.

J Am Soc Nephrol. 2019 Jan;30(1):50-62. doi: 10.1681/ASN.2018040401.

PMID:
30573638
2.

Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death".

Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC.

Mol Cell Biol. 2017 Sep 12;37(19). pii: e00258-17. doi: 10.1128/MCB.00258-17. Print 2017 Oct 1. No abstract available.

3.

Sodium-Glucose Cotransporter 2 Inhibitors and Euglycemic Diabetic Ketoacidosis: Metabolic Acidosis With a Twist.

Jaberi A, Seth B, Steenkamp D, Alexanian S, Borkan SC.

Clin Diabetes. 2016 Oct;34(4):214-216. No abstract available.

4.

Blocking peptides and molecular mimicry as treatment for kidney disease.

Havasi A, Lu W, Cohen HT, Beck L, Wang Z, Igwebuike C, Borkan SC.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1016-F1025. doi: 10.1152/ajprenal.00601.2015. Epub 2016 Sep 21. Review.

5.

Proteinuria causes dysfunctional autophagy in the proximal tubule.

Nolin AC, Mulhern RM, Panchenko MV, Pisarek-Horowitz A, Wang Z, Shirihai O, Borkan SC, Havasi A.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1271-F1279. doi: 10.1152/ajprenal.00125.2016. Epub 2016 Aug 31.

6.

The Role of BCL-2 Family Members in Acute Kidney Injury.

Borkan SC.

Semin Nephrol. 2016 May;36(3):237-50. doi: 10.1016/j.semnephrol.2016.04.001. Review.

PMID:
27339388
7.

Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia.

Gall JM, Wang Z, Bonegio RG, Havasi A, Liesa M, Vemula P, Borkan SC.

J Am Soc Nephrol. 2015 May;26(5):1092-102. doi: 10.1681/ASN.2014010126. Epub 2014 Sep 8.

8.

Recapturing time: a practical approach to time management for physicians.

Gordon CE, Borkan SC.

Postgrad Med J. 2014 May;90(1063):267-72. doi: 10.1136/postgradmedj-2013-132012. Epub 2014 Mar 5. Review.

PMID:
24599633
9.

Nucleophosmin, a critical Bax cofactor in ischemia-induced cell death.

Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC.

Mol Cell Biol. 2013 May;33(10):1916-24. doi: 10.1128/MCB.00015-13. Epub 2013 Mar 4. Erratum in: Mol Cell Biol. 2017 Sep 12;37(19):.

10.

Role of mitofusin 2 in the renal stress response.

Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RG.

PLoS One. 2012;7(1):e31074. doi: 10.1371/journal.pone.0031074. Epub 2012 Jan 26.

11.

Apoptosis and acute kidney injury.

Havasi A, Borkan SC.

Kidney Int. 2011 Jul;80(1):29-40. doi: 10.1038/ki.2011.120. Epub 2011 May 11. Review.

12.

Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress.

Gall JM, Wong V, Pimental DR, Havasi A, Wang Z, Pastorino JG, Bonegio RG, Schwartz JH, Borkan SC.

Kidney Int. 2011 Jun;79(11):1207-16. doi: 10.1038/ki.2010.532. Epub 2011 Mar 23.

13.

Induction of heat shock protein 70 inhibits ischemic renal injury.

Wang Z, Gall JM, Bonegio RG, Havasi A, Hunt CR, Sherman MY, Schwartz JH, Borkan SC.

Kidney Int. 2011 Apr;79(8):861-70. doi: 10.1038/ki.2010.527. Epub 2011 Jan 26.

14.

HSP72 inhibits Smad3 activation and nuclear translocation in renal epithelial-to-mesenchymal transition.

Zhou Y, Mao H, Li S, Cao S, Li Z, Zhuang S, Fan J, Dong X, Borkan SC, Wang Y, Yu X.

J Am Soc Nephrol. 2010 Apr;21(4):598-609. doi: 10.1681/ASN.2009050552. Epub 2010 Feb 4.

15.

GSK3beta promotes apoptosis after renal ischemic injury.

Wang Z, Havasi A, Gall J, Bonegio R, Li Z, Mao H, Schwartz JH, Borkan SC.

J Am Soc Nephrol. 2010 Feb;21(2):284-94. doi: 10.1681/ASN.2009080828. Epub 2010 Jan 21.

16.

Beta-catenin promotes survival of renal epithelial cells by inhibiting Bax.

Wang Z, Havasi A, Gall JM, Mao H, Schwartz JH, Borkan SC.

J Am Soc Nephrol. 2009 Sep;20(9):1919-28. doi: 10.1681/ASN.2009030253. Epub 2009 Aug 20.

17.

Hsp27 inhibits sublethal, Src-mediated renal epithelial cell injury.

Havasi A, Wang Z, Gall JM, Spaderna M, Suri V, Canlas E, Martin JL, Schwartz JH, Borkan SC.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F760-8. doi: 10.1152/ajprenal.00052.2009. Epub 2009 Jun 24.

18.

Palmitate alters neuregulin signaling and biology in cardiac myocytes.

Miller TA, Icli B, Cote GM, Lebrasseur NK, Borkan SC, Pimentel DR, Peng X, Sawyer DB.

Biochem Biophys Res Commun. 2009 Jan 30;379(1):32-7. doi: 10.1016/j.bbrc.2008.11.150. Epub 2008 Dec 12.

19.

HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy.

Mao H, Li Z, Zhou Y, Li Z, Zhuang S, An X, Zhang B, Chen W, Nie J, Wang Z, Borkan SC, Wang Y, Yu X.

Am J Physiol Renal Physiol. 2008 Jul;295(1):F202-14. doi: 10.1152/ajprenal.00468.2007. Epub 2008 Apr 16.

20.

Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism.

Havasi A, Li Z, Wang Z, Martin JL, Botla V, Ruchalski K, Schwartz JH, Borkan SC.

J Biol Chem. 2008 May 2;283(18):12305-13. doi: 10.1074/jbc.M801291200. Epub 2008 Feb 25.

21.

Michael Reese's Mission Commander.

Borkan SC.

Acad Med. 2006 Jun;81(6):556. No abstract available.

PMID:
16728805
22.

A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis.

Li G, Yang Q, Krishnan S, Alexander EA, Borkan SC, Schwartz JH.

Cell Death Differ. 2006 Dec;13(12):2109-17. Epub 2006 May 19.

23.

Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation.

Ruchalski K, Mao H, Li Z, Wang Z, Gillers S, Wang Y, Mosser DD, Gabai V, Schwartz JH, Borkan SC.

J Biol Chem. 2006 Mar 24;281(12):7873-80. Epub 2006 Jan 4.

24.

Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells.

Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner JR, Nakajima A, Borkan SC, Saubermann LJ.

Cancer Res. 2005 Mar 15;65(6):2251-9.

25.

Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes.

Peng X, Guo X, Borkan SC, Bharti A, Kuramochi Y, Calderwood S, Sawyer DB.

J Biol Chem. 2005 Apr 1;280(13):13148-52. Epub 2005 Jan 25.

26.

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.

Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.

Am J Physiol Renal Physiol. 2005 Apr;288(4):F703-13. Epub 2004 Nov 30.

27.

Hsp72 interacts with paxillin and facilitates the reassembly of focal adhesions during recovery from ATP depletion.

Mao H, Wang Y, Li Z, Ruchalski KL, Yu X, Schwartz JH, Borkan SC.

J Biol Chem. 2004 Apr 9;279(15):15472-80. Epub 2004 Jan 12.

28.

HSP72 inhibits apoptosis-inducing factor release in ATP-depleted renal epithelial cells.

Ruchalski K, Mao H, Singh SK, Wang Y, Mosser DD, Li F, Schwartz JH, Borkan SC.

Am J Physiol Cell Physiol. 2003 Dec;285(6):C1483-93. Epub 2003 Aug 20.

29.

hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells.

Mao H, Li F, Ruchalski K, Mosser DD, Schwartz JH, Wang Y, Borkan SC.

J Biol Chem. 2003 May 16;278(20):18214-20. Epub 2003 Feb 28.

30.

Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells.

Wang YH, Knowlton AA, Li FH, Borkan SC.

Cell Stress Chaperones. 2002 Apr;7(2):137-45.

31.

Heat stress prevents mitochondrial injury in ATP-depleted renal epithelial cells.

Li F, Mao HP, Ruchalski KL, Wang YH, Choy W, Schwartz JH, Borkan SC.

Am J Physiol Cell Physiol. 2002 Sep;283(3):C917-26.

32.

Extracorporeal therapies for acute intoxications.

Borkan SC.

Crit Care Clin. 2002 Apr;18(2):393-420, vii. Review.

PMID:
12053840
33.

Molecular chaperones in the kidney.

Borkan SC, Gullans SR.

Annu Rev Physiol. 2002;64:503-27. Review.

PMID:
11826277
34.

c-Src and HSP72 interact in ATP-depleted renal epithelial cells.

Wang YH, Li F, Schwartz JH, Flint PJ, Borkan SC.

Am J Physiol Cell Physiol. 2001 Nov;281(5):C1667-75.

35.

Hepatic alpha 2 mu-globulin localizes to the cytosol of rat proximal tubule cells.

Wang Y, Shia MA, Christensen TG, Borkan SC.

Kidney Int. 2000 Mar;57(3):1015-26.

36.

cAMP-activated anion conductance is associated with expression of CFTR in neonatal mouse cardiac myocytes.

Lader AS, Wang Y, Jackson GR Jr, Borkan SC, Cantiello HF.

Am J Physiol Cell Physiol. 2000 Feb;278(2):C436-50.

37.

Actin filament organization is required for proper cAMP-dependent activation of CFTR.

Prat AG, Cunningham CC, Jackson GR Jr, Borkan SC, Wang Y, Ausiello DA, Cantiello HF.

Am J Physiol. 1999 Dec;277(6):C1160-9. doi: 10.1152/ajpcell.1999.277.6.C1160.

PMID:
10600767
38.

Prior heat stress inhibits apoptosis in adenosine triphosphate-depleted renal tubular cells.

Wang Y, Knowlton AA, Christensen TG, Shih T, Borkan SC.

Kidney Int. 1999 Jun;55(6):2224-35.

39.

Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator.

Cantiello HF, Jackson GR Jr, Grosman CF, Prat AG, Borkan SC, Wang Y, Reisin IL, O'Riordan CR, Ausiello DA.

Am J Physiol. 1998 Mar;274(3):C799-809. doi: 10.1152/ajpcell.1998.274.3.C799.

PMID:
9530112
40.

Heat stress ameliorates ATP depletion-induced sublethal injury in mouse proximal tubule cells.

Borkan SC, Wang YH, Lieberthal W, Burke PR, Schwartz JH.

Am J Physiol. 1997 Mar;272(3 Pt 2):F347-55.

PMID:
9087678
41.

Hepatic alpha 2 mu-globulin: a potential metabolic role in the rat proximal tubule.

Borkan SC, Wang YH, Lam KT, Brecher P, Schwartz JH.

Am J Physiol. 1996 Sep;271(3 Pt 2):F527-38.

PMID:
8853414
42.

Prior heat stress enhances survival of renal epithelial cells after ATP depletion.

Wang YH, Borkan SC.

Am J Physiol. 1996 Jun;270(6 Pt 2):F1057-65.

PMID:
8764325
43.

Heat stress protein-associated cytoprotection of inner medullary collecting duct cells from rat kidney.

Borkan SC, Emami A, Schwartz JH.

Am J Physiol. 1993 Sep;265(3 Pt 2):F333-41.

PMID:
8214091
44.

Transient ischemia or heat stress induces a cytoprotectant protein in rat kidney.

Emami A, Schwartz JH, Borkan SC.

Am J Physiol. 1991 Apr;260(4 Pt 2):F479-85.

PMID:
2012203
45.

Strategies to improve teaching in the ambulatory medicine setting.

Lesky LG, Borkan SC.

Arch Intern Med. 1990 Oct;150(10):2133-7.

PMID:
2222098
46.

Role of oxygen free radical species in in vitro models of proximal tubular ischemia.

Borkan SC, Schwartz JH.

Am J Physiol. 1989 Jul;257(1 Pt 2):F114-25.

PMID:
2750916
47.

Hemoperfusion for N-acetylprocainamide intoxication.

Borkan SC.

Ann Intern Med. 1986 Dec;105(6):965-6. No abstract available.

PMID:
2430494
48.

Uterine lysosomal enzyme activity during ovum implantation and early decidualization.

Moulton BC, Koenig BB, Borkan SC.

Biol Reprod. 1978 Aug;19(1):167-70. No abstract available.

PMID:
687703

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