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Items: 12


The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.

Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC.

Nature. 2018 Jul;559(7713):264-268. doi: 10.1038/s41586-018-0282-0. Epub 2018 Jul 4.


Programmed Cell Death Protein 1-PDL1 Interaction Prevents Heart Damage in Chronic Trypanosoma cruzi Infection.

Fonseca R, Salgado RM, Borges da Silva H, do Nascimento RS, D'Império-Lima MR, Alvarez JM.

Front Immunol. 2018 May 7;9:997. doi: 10.3389/fimmu.2018.00997. eCollection 2018.


P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria.

Salles ÉM, Menezes MN, Siqueira R, Borges da Silva H, Amaral EP, Castillo-Méndez SI, Cunha I, Cassado ADA, Vieira FS, Olivieri DN, Tadokoro CE, Alvarez JM, Coutinho-Silva R, D'Império-Lima MR.

PLoS Pathog. 2017 Aug 31;13(8):e1006595. doi: 10.1371/journal.ppat.1006595. eCollection 2017 Aug.


Retrieving short-term memories of flu.

Borges da Silva H, Jameson SC.

Sci Immunol. 2017 Jan 6;2(7). pii: eaam5330. doi: 10.1126/sciimmunol.aam5330. Epub 2017 Jan 6. Review.


The role of TLR2 in the acute inflammatory response induced by Bothrops atrox snake venom.

Moreira V, Teixeira C, Borges da Silva H, D'Império Lima MR, Dos-Santos MC.

Toxicon. 2016 Aug;118:121-8. doi: 10.1016/j.toxicon.2016.04.042. Epub 2016 Apr 21.


IFN-γ Priming Effects on the Maintenance of Effector Memory CD4(+) T Cells and on Phagocyte Function: Evidences from Infectious Diseases.

Borges da Silva H, Fonseca R, Alvarez JM, D'Império Lima MR.

J Immunol Res. 2015;2015:202816. doi: 10.1155/2015/202816. Epub 2015 Oct 5. Review.


Splenic Macrophage Subsets and Their Function during Blood-Borne Infections.

Borges da Silva H, Fonseca R, Pereira RM, Cassado Ados A, Álvarez JM, D'Império Lima MR.

Front Immunol. 2015 Sep 22;6:480. doi: 10.3389/fimmu.2015.00480. eCollection 2015. Review.


In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria.

Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE.

PLoS Pathog. 2015 Feb 6;11(2):e1004598. doi: 10.1371/journal.ppat.1004598. eCollection 2015 Feb.


Chagas disease: still many unsolved issues.

Álvarez JM, Fonseca R, Borges da Silva H, Marinho CR, Bortoluci KR, Sardinha LR, Epiphanio S, D'Império Lima MR.

Mediators Inflamm. 2014;2014:912965. doi: 10.1155/2014/912965. Epub 2014 Jun 29. Review.


The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom.

Moreira V, Teixeira C, Borges da Silva H, D'Império Lima MR, Dos-Santos MC.

Toxicon. 2013 Jun 1;67:37-46. doi: 10.1016/j.toxicon.2013.02.010. Epub 2013 Mar 5.


Local inflammatory events induced by Bothrops atrox snake venom and the release of distinct classes of inflammatory mediators.

Moreira V, Dos-Santos MC, Nascimento NG, Borges da Silva H, Fernandes CM, D'Império Lima MR, Teixeira C.

Toxicon. 2012 Jul;60(1):12-20. doi: 10.1016/j.toxicon.2012.03.004. Epub 2012 Mar 20.


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