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Items: 1 to 50 of 343

1.

Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.

Vandermeeren M, Borgers M, Van Kolen K, Theunis C, Vasconcelos B, Bottelbergs A, Wintmolders C, Daneels G, Willems R, Dockx K, Delbroek L, Marreiro A, Ver Donck L, Sousa C, Nanjunda R, Lacy E, Van De Casteele T, Van Dam D, De Deyn PP, Kemp JA, Malia TJ, Mercken MH.

J Alzheimers Dis. 2018;65(1):265-281. doi: 10.3233/JAD-180404.

PMID:
30040731
2.

Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422 containing epitope on pathological tau.

van Ameijde J, Crespo R, Janson R, Juraszek J, Siregar B, Verveen H, Sprengers I, Nahar T, Hoozemans JJ, Steinbacher S, Willems R, Delbroek L, Borgers M, Dockx K, Van Kolen K, Mercken M, Pascual G, Koudstaal W, Apetri A.

Acta Neuropathol Commun. 2018 Jul 12;6(1):59. doi: 10.1186/s40478-018-0562-9.

3.

A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.

Apetri A, Crespo R, Juraszek J, Pascual G, Janson R, Zhu X, Zhang H, Keogh E, Holland T, Wadia J, Verveen H, Siregar B, Mrosek M, Taggenbrock R, Ameijde J, Inganäs H, van Winsen M, Koldijk MH, Zuijdgeest D, Borgers M, Dockx K, Stoop EJM, Yu W, Brinkman-van der Linden EC, Ummenthum K, van Kolen K, Mercken M, Steinbacher S, de Marco D, Hoozemans JJ, Wilson IA, Koudstaal W, Goudsmit J.

Acta Neuropathol Commun. 2018 May 31;6(1):43. doi: 10.1186/s40478-018-0543-z.

4.

Clusterin signals via ApoER2/VLDLR and induces meiosis of male germ cells.

Riaz MA, Stammler A, Borgers M, Konrad L.

Am J Transl Res. 2017 Mar 15;9(3):1266-1276. eCollection 2017.

5.

Using Human iPSC-Derived Neurons to Model TAU Aggregation.

Verheyen A, Diels A, Dijkmans J, Oyelami T, Meneghello G, Mertens L, Versweyveld S, Borgers M, Buist A, Peeters P, Cik M.

PLoS One. 2015 Dec 31;10(12):e0146127. doi: 10.1371/journal.pone.0146127. eCollection 2015.

6.

Response to exercise and mechanical efficiency in non-ischaemic stunning, induced by short-term rapid pacing in dogs: a role for calcium?

De Pauw M, Mubagwa K, Hodeige D, Borgers M, Flameng W, Van de Voorde J, Heyndrickx GR.

Acta Physiol (Oxf). 2017 Apr;219(4):768-780. doi: 10.1111/apha.12629. Epub 2015 Dec 15.

PMID:
26560191
7.

Erratum to: Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity.

Hick M, Herrmann U, Weyer SW, Mallm JP, Tschäpe JA, Borgers M, Mercken M, Roth FC, Draguhn A, Slomianka L, Wolfer DP, Korte M, Müller UC.

Acta Neuropathol. 2015 Jan;129(1):161-2. doi: 10.1007/s00401-014-1374-z. No abstract available.

PMID:
25527084
8.

Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity.

Hick M, Herrmann U, Weyer SW, Mallm JP, Tschäpe JA, Borgers M, Mercken M, Roth FC, Draguhn A, Slomianka L, Wolfer DP, Korte M, Müller UC.

Acta Neuropathol. 2015 Jan;129(1):21-37. doi: 10.1007/s00401-014-1368-x. Epub 2014 Nov 29. Erratum in: Acta Neuropathol. 2015 Jan;129(1):161-2.

PMID:
25432317
9.

Role of compensatory meiosis mechanisms in human spermatogenesis.

Borgers M, Wolter M, Hentrich A, Bergmann M, Stammler A, Konrad L.

Reproduction. 2014 Sep;148(3):315-20. doi: 10.1530/REP-14-0279. Epub 2014 Jul 1.

PMID:
24987152
10.

Chronic hibernating myocardium in sheep can occur without degenerating events and is reversed after revascularization.

Verheyen F, Racz R, Borgers M, Driesen RB, Lenders MH, Flameng WJ.

Cardiovasc Pathol. 2014 May-Jun;23(3):160-8. doi: 10.1016/j.carpath.2014.01.003. Epub 2014 Jan 10.

PMID:
24529701
11.

Reconviction rates after suspended sentences: comparison of the effects of different types of suspended sentences on reconviction in the Netherlands.

Aarten PG, Denkers A, Borgers MJ, van der Laan PH.

Int J Offender Ther Comp Criminol. 2015 Feb;59(2):143-58. doi: 10.1177/0306624X13508929. Epub 2013 Oct 31.

PMID:
24178921
12.

Soluble amyloid-β precursor protein binds its cell surface receptor in a cooperative fashion with glypican and syndecan proteoglycans.

Reinhard C, Borgers M, David G, De Strooper B.

J Cell Sci. 2013 Nov 1;126(Pt 21):4856-61. doi: 10.1242/jcs.137919. Epub 2013 Aug 28.

13.

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Tesseur I, Lo AC, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M, Gijsen H, Moechars D, Mercken M, Kemp J, D'Hooge R, De Strooper B.

Science. 2013 May 24;340(6135):924-e. doi: 10.1126/science.1233937.

14.

The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo.

Zhou L, Barão S, Laga M, Bockstael K, Borgers M, Gijsen H, Annaert W, Moechars D, Mercken M, Gevaert K, De Strooper B.

J Biol Chem. 2012 Jul 27;287(31):25927-40. doi: 10.1074/jbc.M112.377465. Epub 2012 Jun 12. Erratum in: J Biol Chem. 2012 Sep 28;287(40):33719. Gevaer, Kris [corrected to Gevaert, Kris].

15.

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.

Chávez-Gutiérrez L, Bammens L, Benilova I, Vandersteen A, Benurwar M, Borgers M, Lismont S, Zhou L, Van Cleynenbreugel S, Esselmann H, Wiltfang J, Serneels L, Karran E, Gijsen H, Schymkowitz J, Rousseau F, Broersen K, De Strooper B.

EMBO J. 2012 May 16;31(10):2261-74. doi: 10.1038/emboj.2012.79. Epub 2012 Apr 13.

16.

Novel fungicidal benzylsulfanyl-phenylguanidines.

Thevissen K, Pellens K, De Brucker K, François IE, Chow KK, Meert EM, Meert W, Van Minnebruggen G, Borgers M, Vroome V, Levin J, De Vos D, Maes L, Cos P, Cammue BP.

Bioorg Med Chem Lett. 2011 Jun 15;21(12):3686-92. doi: 10.1016/j.bmcl.2011.04.075. Epub 2011 Apr 24.

PMID:
21576022
17.

The effect of antifungal treatment on the vaginal flora of women with vulvo-vaginal yeast infection with or without bacterial vaginosis.

Donders G, Bellen G, Ausma J, Verguts L, Vaneldere J, Hinoul P, Borgers M, Janssens D.

Eur J Clin Microbiol Infect Dis. 2011 Jan;30(1):59-63. doi: 10.1007/s10096-010-1052-6. Epub 2010 Sep 28.

PMID:
20878199
18.

A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast.

Bink A, Govaert G, François IE, Pellens K, Meerpoel L, Borgers M, Van Minnebruggen G, Vroome V, Cammue BP, Thevissen K.

FEMS Yeast Res. 2010 Nov;10(7):812-8. doi: 10.1111/j.1567-1364.2010.00663.x. Epub 2010 Aug 18.

19.

Membrane rafts are involved in intracellular miconazole accumulation in yeast cells.

François IE, Bink A, Vandercappellen J, Ayscough KR, Toulmay A, Schneiter R, van Gyseghem E, Van den Mooter G, Borgers M, Vandenbosch D, Coenye T, Cammue BP, Thevissen K.

J Biol Chem. 2009 Nov 20;284(47):32680-5. doi: 10.1074/jbc.M109.014571. Epub 2009 Sep 25.

20.

Design and synthesis of a series of piperazine-1-carboxamidine derivatives with antifungal activity resulting from accumulation of endogenous reactive oxygen species.

François IE, Thevissen K, Pellens K, Meert EM, Heeres J, Freyne E, Coesemans E, Viellevoye M, Deroose F, Martinez Gonzalez S, Pastor J, Corens D, Meerpoel L, Borgers M, Ausma J, Dispersyn GD, Cammue BP.

ChemMedChem. 2009 Oct;4(10):1714-21. doi: 10.1002/cmdc.200900249.

PMID:
19705386
21.

Re-expression of alpha skeletal actin as a marker for dedifferentiation in cardiac pathologies.

Driesen RB, Verheyen FK, Debie W, Blaauw E, Babiker FA, Cornelussen RN, Ausma J, Lenders MH, Borgers M, Chaponnier C, Ramaekers FC.

J Cell Mol Med. 2009 May;13(5):896-908. doi: 10.1111/j.1582-4934.2008.00523.x.

22.

Expression of retinoid-regulated genes in lamellar ichthyosis vs. healthy control epidermis: changes after oral treatment with liarozole.

Pavez Loriè E, Gånemo A, Borgers M, Wouters L, Blockhuys S, van de Plassche L, Törmä H, Vahlquist A.

Acta Derm Venereol. 2009;89(1):12-20. doi: 10.2340/00015555-0573.

23.

Topical treatment with CYP26 inhibitor talarozole (R115866) dose dependently alters the expression of retinoid-regulated genes in normal human epidermis.

Pavez Loriè E, Cools M, Borgers M, Wouters L, Shroot B, Hagforsen E, Törmä H, Vahlquist A.

Br J Dermatol. 2009 Jan;160(1):26-36. doi: 10.1111/j.1365-2133.2008.08895.x. Epub 2008 Oct 21.

PMID:
19016711
24.

Ultra stable ordered mesoporous phenol/formaldehyde polymers as a heterogeneous support for vanadium oxide.

Muylaert I, Borgers M, Bruneel E, Schaubroeck J, Verpoort F, Van Der Voort P.

Chem Commun (Camb). 2008 Oct 7;(37):4475-7. doi: 10.1039/b808566h. Epub 2008 Jul 29.

PMID:
18802595
25.

Efficacy of a single oral dose of 200 mg pramiconazole in vulvovaginal yeast infections: an exploratory phase IIa trial.

Donders G, Ausma J, Wouters L, Cauwenbergh G, Borgers M, Janssens D.

Acta Derm Venereol. 2008;88(5):462-6. doi: 10.2340/00015555-0494.

26.

Novelties in the multifaceted miconazole effects on skin disorders.

Quatresooz P, Vroome V, Borgers M, Cauwenbergh G, Piérard GE.

Expert Opin Pharmacother. 2008 Aug;9(11):1927-34. doi: 10.1517/14656566.9.11.1927 . Review.

PMID:
18627330
27.

Cardiotin localization in mitochondria of cardiomyocytes in vivo and in vitro and its down-regulation during dedifferentiation.

Driesen RB, Verheyen FK, Schaart G, de Mazière A, Viebahn C, Prinzen FW, Lenders MH, Debie W, Totzeck A, Borgers M, Ramaekers FC.

Cardiovasc Pathol. 2009 Jan-Feb;18(1):19-27. doi: 10.1016/j.carpath.2007.12.008. Epub 2008 Feb 20.

PMID:
18402829
28.

The efficacy of oral treatment with pramiconazole in tinea pedis and tinea cruris/corporis: two exploratory phase IIa trials.

Decroix J, Ausma J, Cauwenbergh G, Borgers M, Wouters L.

Br J Dermatol. 2008 Apr;158(4):854-6. doi: 10.1111/j.1365-2133.2007.08420.x. Epub 2008 Jan 30. No abstract available.

PMID:
18241269
29.

The role of ketoconazole in seborrheic dermatitis.

Borgers M, Degreef H.

Cutis. 2007 Oct;80(4):359-63. Review.

PMID:
18038701
30.

Retinoic acid metabolism blocking agents (RAMBAs): a new paradigm in the treatment of hyperkeratotic disorders.

Verfaille CJ, Borgers M, van Steensel MA.

J Dtsch Dermatol Ges. 2008 May;6(5):355-64. Epub 2007 Oct 16. Review. English, German. Erratum in: J Dtsch Dermatol Ges. 2008 Jul;6(7):610.

PMID:
17941881
31.

A new ketoconazole topical gel formulation in seborrhoeic dermatitis: an updated review of the mechanism.

Faergemann J, Borgers M, Degreef H.

Expert Opin Pharmacother. 2007 Jun;8(9):1365-71. Review.

PMID:
17563270
32.

Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast.

Thevissen K, Ayscough KR, Aerts AM, Du W, De Brucker K, Meert EM, Ausma J, Borgers M, Cammue BP, François IE.

J Biol Chem. 2007 Jul 27;282(30):21592-7. Epub 2007 Jun 6.

33.

The efficacy of oral treatment with pramiconazole in pityriasis versicolor: a phase II a trial.

Faergemann J, Ausma J, Vandeplassche L, Borgers M.

Br J Dermatol. 2007 Jun;156(6):1385-8. No abstract available.

PMID:
17535237
34.

Oral R115866 in the treatment of moderate to severe facial acne vulgaris: an exploratory study.

Verfaille CJ, Coel M, Boersma IH, Mertens J, Borgers M, Roseeuw D.

Br J Dermatol. 2007 Jul;157(1):122-6. Epub 2007 Apr 25.

PMID:
17459036
35.

Structural remodelling of cardiomyocytes in the border zone of infarcted rabbit heart.

Driesen RB, Verheyen FK, Dijkstra P, Thoné F, Cleutjens JP, Lenders MH, Ramaekers FC, Borgers M.

Mol Cell Biochem. 2007 Aug;302(1-2):225-32. Epub 2007 Mar 27.

PMID:
17387581
36.

A pilot study on seborrheic dermatitis using pramiconazole as a potent oral anti-Malassezia agent.

Piérard GE, Ausma J, Henry F, Vroome V, Wouters L, Borgers M, Cauwenbergh G, Piérard-Franchimont C.

Dermatology. 2007;214(2):162-9.

PMID:
17341867
37.

Absence of an active metabolite for the triazole antifungal pramiconazole.

Ausma J, Pennick G, Bohets H, van de Velde V, Borgers M, Fothergill A.

Acta Derm Venereol. 2007;87(1):22-6.

38.

In vitro activity of R126638 and ketoconazole against Malassezia species.

Faergemann J, Ausma J, Borgers M.

Acta Derm Venereol. 2006;86(4):312-5.

39.

Spatiotemporal pattern of neuroinflammation after impact-acceleration closed head injury in the rat.

Rooker S, Jander S, Van Reempts J, Stoll G, Jorens PG, Borgers M, Verlooy J.

Mediators Inflamm. 2006;2006(1):90123.

40.

Effect of a single overnight topical application of miconazole nitrate paste on acne papules.

Flagothier C, Vroome V, Borgers M, Wang X, Cauwenbergh G, Piérard GE.

Int J Dermatol. 2006 Mar;45(3):316-9.

PMID:
16533239
41.

Structural adaptation in adult rabbit ventricular myocytes: influence of dynamic physical interaction with fibroblasts.

Driesen RB, Verheyen FK, Dispersyn GD, Thoné F, Lenders MH, Ramaekers FC, Borgers M.

Cell Biochem Biophys. 2006;44(1):119-28.

PMID:
16456240
42.

Fungal infections of the skin: infection process and antimycotic therapy.

Borgers M, Degreef H, Cauwenbergh G.

Curr Drug Targets. 2005 Dec;6(8):849-62. Review.

PMID:
16375669
43.

Activity of the triazole antifungal r126638 as assessed by corneofungimetry.

Piérard-Franchimont C, Ausma J, Wouters L, Vroome V, Vandeplassche L, Borgers M, Cauwenbergh G, Piérard GE.

Skin Pharmacol Physiol. 2006;19(1):50-6. Epub 2005 Oct 20.

PMID:
16247249
44.

Pentobarbital fails to reduce cerebral oxygen consumption early after non-hemorrhagic closed head injury in rats.

De Visscher G, Rooker S, Jorens P, Verlooy J, Borgers M, Reneman RS, Van Rossem K, Flameng W.

J Neurotrauma. 2005 Jul;22(7):793-806.

PMID:
16004582
45.

Partial cell fusion: a newly recognized type of communication between dedifferentiating cardiomyocytes and fibroblasts.

Driesen RB, Dispersyn GD, Verheyen FK, van den Eijnde SM, Hofstra L, Thoné F, Dijkstra P, Debie W, Borgers M, Ramaekers FC.

Cardiovasc Res. 2005 Oct 1;68(1):37-46.

PMID:
15964558
46.

End-diastolic myofiber stress and ejection strain increase with ventricular volume overload--Serial in-vivo analyses in dogs with complete atrioventricular block.

Donker DW, Volders PG, Arts T, Bekkers BC, Hofstra L, Spätjens RL, Beekman JD, Borgers M, Crijns HJ, Vos MA.

Basic Res Cardiol. 2005 Jul;100(4):372-82. Epub 2005 Apr 1.

PMID:
15795796
47.

Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology.

Meerpoel L, Backx LJ, Van der Veken LJ, Heeres J, Corens D, De Groot A, Odds FC, Van Gerven F, Woestenborghs FA, Van Breda A, Oris M, van Dorsselaer P, Willemsens GH, Vermuyten KJ, Marichal PJ, Vanden Bossche HF, Ausma J, Borgers M.

J Med Chem. 2005 Mar 24;48(6):2184-93.

PMID:
15771461
48.

Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines.

Janssens F, Leenaerts J, Diels G, De Boeck B, Megens A, Langlois X, van Rossem K, Beetens J, Borgers M.

J Med Chem. 2005 Mar 24;48(6):2154-66.

PMID:
15771458
49.

Temporal and spatial variations in structural protein expression during the progression from stunned to hibernating myocardium.

Thijssen VL, Borgers M, Lenders MH, Ramaekers FC, Suzuki G, Palka B, Fallavollita JA, Thomas SA, Canty JM Jr.

Circulation. 2004 Nov 23;110(21):3313-21. Epub 2004 Nov 15.

PMID:
15545518
50.

The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis.

Vanden Bossche H, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, Meerpoel L, Odds F, Borgers M.

Antimicrob Agents Chemother. 2004 Sep;48(9):3272-8.

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