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Items: 1 to 50 of 323

1.

The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins.

Kashirina DN, Percy AJ, Pastushkova LK, Borchers CH, Kireev KS, Ivanisenko VA, Kononikhin AS, Nikolaev EN, Larina IM.

BMC Med Genomics. 2019 Mar 13;12(Suppl 2):45. doi: 10.1186/s12920-019-0490-y.

2.

Chaperone activation and client binding of a 2-cysteine peroxiredoxin.

Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U.

Nat Commun. 2019 Feb 8;10(1):659. doi: 10.1038/s41467-019-08565-8.

3.

Acute Ethanol Exposure Augments Low-Dose UVB-Mediated Systemic Immunosuppression via Enhanced Production of Platelet-Activating Factor Receptor Agonists.

Travers JB, Weyerbacher J, Ocana JA, Borchers C, Rapp CM, Sahu RP.

J Invest Dermatol. 2019 Jan 23. pii: S0022-202X(19)30009-0. doi: 10.1016/j.jid.2018.11.034. [Epub ahead of print] No abstract available.

PMID:
30682347
4.

Multiplexed LC-ESI-MRM-MS-based Assay for Identification of Coronary Artery Disease Biomarkers in Human Plasma.

Anwar MA, Dai DL, Wilson-McManus J, Smith D, Francis GA, Borchers CH, McManus BM, Hill JS, Cohen Freue GV.

Proteomics Clin Appl. 2019 Jan 11:e1700111. doi: 10.1002/prca.201700111. [Epub ahead of print]

PMID:
30632678
5.

Changing the Apoptosis Pathway through Evolutionary Protein Design.

Shultis D, Mitra P, Huang X, Johnson J, Khattak NA, Gray F, Piper C, Czajka J, Hansen L, Wan B, Chinnaswamy K, Liu L, Wang M, Pan J, Stuckey J, Cierpicki T, Borchers CH, Wang S, Lei M, Zhang Y.

J Mol Biol. 2019 Feb 15;431(4):825-841. doi: 10.1016/j.jmb.2018.12.016. Epub 2019 Jan 6.

PMID:
30625288
6.

Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.

Wang R, Sheps JA, Liu L, Han J, Chen PSK, Lamontagne J, Wilson PD, Welch I, Borchers CH, Ling V.

J Lipid Res. 2019 Jan;60(1):85-97. doi: 10.1194/jlr.M088070. Epub 2018 Nov 11.

PMID:
30416103
7.

Isotope-labeling derivatization with 3-nitrophenylhydrazine for LC/multiple-reaction monitoring-mass-spectrometry-based quantitation of carnitines in dried blood spots.

Han J, Higgins R, Lim MD, Atkinson K, Yang J, Lin K, Borchers CH.

Anal Chim Acta. 2018 Dec 11;1037:177-187. doi: 10.1016/j.aca.2018.01.045. Epub 2018 Feb 5.

8.

Molecular phenotyping of laboratory mouse strains using 500 multiple reaction monitoring mass spectrometry plasma assays.

Michaud SA, Sinclair NJ, Pětrošová H, Palmer AL, Pistawka AJ, Zhang S, Hardie DB, Mohammed Y, Eshghi A, Richard VR, Sickmann A, Borchers CH.

Commun Biol. 2018 Jun 27;1:78. doi: 10.1038/s42003-018-0087-6. eCollection 2018.

9.

Immuno-MALDI (iMALDI) mass spectrometry for the analysis of proteins in signaling pathways.

Popp R, Li H, Borchers CH.

Expert Rev Proteomics. 2018 Sep;15(9):701-708. doi: 10.1080/14789450.2018.1516147. Epub 2018 Sep 17.

PMID:
30169113
10.

Immuno-MALDI-TOF-MS in the Clinic.

Zahedi RP, Parker CE, Borchers CH.

Clin Chem. 2018 Sep;64(9):1271-1272. doi: 10.1373/clinchem.2018.292136. Epub 2018 Jul 17. No abstract available.

PMID:
30018057
11.

Validation of a proteomic biomarker panel to diagnose minor-stroke and transient ischaemic attack: phase 2 of SpecTRA, a large scale translational study.

Penn AM, Bibok MB, Saly VK, Coutts SB, Lesperance ML, Balshaw RF, Votova K, Croteau NS, Trivedi A, Jackson AM, Hegedus J, Klourfeld E, Yu AYX, Zerna C, Modi J, Barber PA, Hoag G, Borchers CH; SpecTRA study group.

Biomarkers. 2018 Dec;23(8):793-803. doi: 10.1080/1354750X.2018.1499130. Epub 2018 Aug 23.

PMID:
30010432
12.

Maternal Apolipoprotein B100 Serum Levels are Diminished in Pregnancies with Intrauterine Growth Restriction and Differentiate from Controls.

Wölter M, Okai CA, Smith DS, Ruß M, Rath W, Pecks U, Borchers CH, Glocker MO.

Proteomics Clin Appl. 2018 Nov;12(6):e1800017. doi: 10.1002/prca.201800017. Epub 2018 Jul 23.

PMID:
29956482
13.

Genetic Variation in 9p21 and the Plasma Proteome.

Mahdavi S, Jenkins DJA, Borchers CH, El-Sohemy A.

J Proteome Res. 2018 Aug 3;17(8):2649-2656. doi: 10.1021/acs.jproteome.8b00117. Epub 2018 Jul 19.

PMID:
29905076
14.

Detecting post-translational modification signatures as potential biomarkers in clinical mass spectrometry.

Mnatsakanyan R, Shema G, Basik M, Batist G, Borchers CH, Sickmann A, Zahedi RP.

Expert Rev Proteomics. 2018 Jun;15(6):515-535. doi: 10.1080/14789450.2018.1483340.

PMID:
29893147
15.

Enhanced Platelet-Activating Factor Synthesis Facilitates Acute and Delayed Effects of Ethanol-Intoxicated Thermal Burn Injury.

Harrison KA, Romer E, Weyerbacher J, Ocana JA, Sahu RP, Murphy RC, Kelly LE, Smith TA, Rapp CM, Borchers C, Cool DR, Li G, Simman R, Travers JB.

J Invest Dermatol. 2018 Nov;138(11):2461-2469. doi: 10.1016/j.jid.2018.04.039. Epub 2018 May 30.

PMID:
29857067
16.

MRMAssayDB: an integrated resource for validated targeted proteomics assays.

Bhowmick P, Mohammed Y, Borchers CH.

Bioinformatics. 2018 Oct 15;34(20):3566-3571. doi: 10.1093/bioinformatics/bty385.

17.

How iMALDI can improve clinical diagnostics.

Popp R, Basik M, Spatz A, Batist G, Zahedi RP, Borchers CH.

Analyst. 2018 May 15;143(10):2197-2203. doi: 10.1039/c8an00094h. Review.

PMID:
29713694
18.

The Special Issue: Clinical Proteomics for Precision Medicine.

Parker CE, Borchers CH.

Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201600144. No abstract available.

PMID:
29521035
19.

Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease.

Boczonadi V, King MS, Smith AC, Olahova M, Bansagi B, Roos A, Eyassu F, Borchers C, Ramesh V, Lochmüller H, Polvikoski T, Whittaker RG, Pyle A, Griffin H, Taylor RW, Chinnery PF, Robinson AJ, Kunji ERS, Horvath R.

Genet Med. 2018 Oct;20(10):1224-1235. doi: 10.1038/gim.2017.251. Epub 2018 Mar 8.

20.

Metabolomic insights into the effects of thyroid hormone on Rana [Lithobates] catesbeiana metamorphosis using whole-body Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI).

Luehr TC, Koide EM, Wang X, Han J, Borchers CH, Helbing CC.

Gen Comp Endocrinol. 2018 Sep 1;265:237-245. doi: 10.1016/j.ygcen.2018.02.012. Epub 2018 Feb 19.

PMID:
29470956
21.

Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations.

Liu T, Wang RX, Han J, Hao CZ, Qiu YL, Yan YY, Li LT, Wang NL, Gong JY, Lu Y, Zhang MH, Xie XB, Yang JC, You YJ, Li JQ, Knisely AS, Borchers CH, Ling V, Wang JS.

Liver Int. 2018 Sep;38(9):1676-1685. doi: 10.1111/liv.13714. Epub 2018 Mar 12.

PMID:
29412511
22.

Verification of a proteomic biomarker panel to diagnose minor stroke and transient ischaemic attack: phase 1 of SpecTRA, a large scale translational study.

Penn AM, Bibok MB, Saly VK, Coutts SB, Lesperance ML, Balshaw RF, Votova K, Croteau NS, Trivedi A, Jackson AM, Hegedus J, Klourfeld E, Yu AYX, Zerna C, Borchers CH; SpecTRA study group.

Biomarkers. 2018 May - Jun;23(4):392-405. doi: 10.1080/1354750X.2018.1434681. Epub 2018 Feb 12.

PMID:
29385837
23.

Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project.

Penn AM, Saly V, Trivedi A, Lesperance ML, Votova K, Jackson AM, Croteau NS, Balshaw RF, Bibok MB, Smith DS, Lam KK, Morrison J, Lu L, Coutts SB, Borchers CH.

Transl Stroke Res. 2018 Dec;9(6):590-599. doi: 10.1007/s12975-018-0609-z. Epub 2018 Jan 24.

24.

The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability.

Dilworth D, Gudavicius G, Xu X, Boyce AKJ, O'Sullivan C, Serpa JJ, Bilenky M, Petrochenko EV, Borchers CH, Hirst M, Swayne LA, Howard P, Nelson CJ.

Nucleic Acids Res. 2018 Mar 16;46(5):2459-2478. doi: 10.1093/nar/gky008.

25.

An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung Cancer Pleural Effusions.

Perzanowska A, Fatalska A, Wojtas G, Lewandowicz A, Michalak A, Krasowski G, Borchers CH, Dadlez M, Domanski D.

Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201700084. Epub 2018 Feb 7.

PMID:
29352525
26.

Top-Down Hydrogen-Deuterium Exchange Analysis of Protein Structures Using Ultraviolet Photodissociation.

Brodie NI, Huguet R, Zhang T, Viner R, Zabrouskov V, Pan J, Petrotchenko EV, Borchers CH.

Anal Chem. 2018 Mar 6;90(5):3079-3082. doi: 10.1021/acs.analchem.7b03655. Epub 2018 Feb 1.

PMID:
29336549
27.

Proteomic Profiling of Leishmania donovani Promastigote Subcellular Organelles.

Jardim A, Hardie DB, Boitz J, Borchers CH.

J Proteome Res. 2018 Mar 2;17(3):1194-1215. doi: 10.1021/acs.jproteome.7b00817. Epub 2018 Feb 5.

PMID:
29332401
28.

Multiplexed targeted proteomic assay to assess coagulation factor concentrations and thrombosis-associated cancer.

Mohammed Y, van Vlijmen BJ, Yang J, Percy AJ, Palmblad M, Borchers CH, Rosendaal FR.

Blood Adv. 2017 Jun 20;1(15):1080-1087. doi: 10.1182/bloodadvances.2017007955. eCollection 2017 Jun 27.

29.

Immunohistochemical comparative analysis of GFAP, MAP - 2, NOGO - A, OLIG - 2 and WT - 1 expression in WHO 2016 classified neuroepithelial tumours and their prognostic value.

Schwab DE, Lepski G, Borchers C, Trautmann K, Paulsen F, Schittenhelm J.

Pathol Res Pract. 2018 Jan;214(1):15-24. doi: 10.1016/j.prp.2017.12.009. Epub 2017 Dec 14.

PMID:
29258767
30.

Multiple Reaction Monitoring Using Double Isotopologue Peptide Standards for Protein Quantification.

Eshghi A, Borchers CH.

Methods Mol Biol. 2018;1788:193-214. doi: 10.1007/7651_2017_112.

PMID:
29256172
31.

Thrombospondin-1 and disease progression in dysferlinopathy.

Urao N, Mirza RE, Corbiere TF, Hollander Z, Borchers CH, Koh TJ.

Hum Mol Genet. 2017 Dec 15;26(24):4951-4960. doi: 10.1093/hmg/ddx378.

PMID:
29206970
32.

Short-Term Stabilities of 21 Amino Acids in Dried Blood Spots.

Han J, Higgins R, Lim MD, Lin K, Yang J, Borchers CH.

Clin Chem. 2018 Feb;64(2):400-402. doi: 10.1373/clinchem.2017.278457. Epub 2017 Nov 2. No abstract available.

33.

The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module.

Dilworth D, Upadhyay SK, Bonnafous P, Edoo AB, Bourbigot S, Pesek-Jardim F, Gudavicius G, Serpa JJ, Petrotchenko EV, Borchers CH, Nelson CJ, Mackereth CD.

Nucleic Acids Res. 2017 Nov 16;45(20):11989-12004. doi: 10.1093/nar/gkx852.

34.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.

35.

ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments.

Mohammed Y, Pan J, Zhang S, Han J, Borchers CH.

Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201600180. Epub 2017 Oct 25.

36.

Peptide and Protein Quantification Using Automated Immuno-MALDI (iMALDI).

Li H, Popp R, Frohlich B, Chen MX, Borchers CH.

J Vis Exp. 2017 Aug 18;(126). doi: 10.3791/55933.

PMID:
28872133
37.

Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors.

Popp R, Li H, LeBlanc A, Mohammed Y, Aguilar-Mahecha A, Chambers AG, Lan C, Poetz O, Basik M, Batist G, Borchers CH.

Anal Chem. 2017 Oct 3;89(19):10592-10600. doi: 10.1021/acs.analchem.7b02934. Epub 2017 Sep 20.

PMID:
28853539
38.

Peptide biomarkers used for the selective breeding of a complex polygenic trait in honey bees.

Guarna MM, Hoover SE, Huxter E, Higo H, Moon KM, Domanski D, Bixby MEF, Melathopoulos AP, Ibrahim A, Peirson M, Desai S, Micholson D, White R, Borchers CH, Currie RW, Pernal SF, Foster LJ.

Sci Rep. 2017 Aug 21;7(1):8381. doi: 10.1038/s41598-017-08464-2.

39.

Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts.

M Larina I, Percy AJ, Yang J, Borchers CH, M Nosovsky A, I Grigoriev A, N Nikolaev E.

Sci Rep. 2017 Aug 15;7(1):8142. doi: 10.1038/s41598-017-08432-w.

40.

An online 2D-reversed-phase - Reversed-phase chromatographic method for sensitive and robust plasma protein quantitation.

Richard VR, Domanski D, Percy AJ, Borchers CH.

J Proteomics. 2017 Sep 25;168:28-36. doi: 10.1016/j.jprot.2017.07.018. Epub 2017 Jul 28.

41.

Microfluidic-Mass Spectrometry Interfaces for Translational Proteomics.

Pedde RD, Li H, Borchers CH, Akbari M.

Trends Biotechnol. 2017 Oct;35(10):954-970. doi: 10.1016/j.tibtech.2017.06.006. Epub 2017 Jul 26. Review.

PMID:
28755975
42.

Repression of Salmonella host cell invasion by aromatic small molecules from the human fecal metabolome.

Peixoto RJM, Alves ES, Wang M, Ferreira RBR, Granato A, Han J, Gill H, Jacobson K, Lobo LA, Domingues RMCP, Borchers CH, Davies JE, Finlay BB, Antunes LCM.

Appl Environ Microbiol. 2017 Jul 28. pii: AEM.01148-17. doi: 10.1128/AEM.01148-17. [Epub ahead of print]

43.

Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations.

Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH.

Sci Adv. 2017 Jul 7;3(7):e1700479. doi: 10.1126/sciadv.1700479. eCollection 2017 Jul.

44.

Multiplexed MRM-Based Protein Quantitation Using Two Different Stable Isotope-Labeled Peptide Isotopologues for Calibration.

LeBlanc A, Michaud SA, Percy AJ, Hardie DB, Yang J, Sinclair NJ, Proudfoot JI, Pistawka A, Smith DS, Borchers CH.

J Proteome Res. 2017 Jul 7;16(7):2527-2536. doi: 10.1021/acs.jproteome.7b00094. Epub 2017 Jun 2.

PMID:
28516774
45.

Current trends in quantitative proteomics - an update.

Li H, Han J, Pan J, Liu T, Parker CE, Borchers CH.

J Mass Spectrom. 2017 May;52(5):319-341. doi: 10.1002/jms.3932. Review.

PMID:
28418607
46.

Enteric Helminths Promote Salmonella Coinfection by Altering the Intestinal Metabolome.

Reynolds LA, Redpath SA, Yurist-Doutsch S, Gill N, Brown EM, van der Heijden J, Brosschot TP, Han J, Marshall NC, Woodward SE, Valdez Y, Borchers CH, Perona-Wright G, Finlay BB.

J Infect Dis. 2017 Apr 15;215(8):1245-1254. doi: 10.1093/infdis/jix141.

47.

Prolonged Temozolomide Maintenance Therapy in Newly Diagnosed Glioblastoma.

Skardelly M, Dangel E, Gohde J, Noell S, Behling F, Lepski G, Borchers C, Koch M, Schittenhelm J, Bisdas S, Naumann A, Paulsen F, Zips D, von Hehn U, Ritz R, Tatagiba MS, Tabatabai G.

Oncologist. 2017 May;22(5):570-575. doi: 10.1634/theoncologist.2016-0347. Epub 2017 Mar 30.

48.

A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury.

Streijger F, Skinnider MA, Rogalski JC, Balshaw R, Shannon CP, Prudova A, Belanger L, Ritchie L, Tsang A, Christie S, Parent S, Mac-Thiong JM, Bailey C, Urquhart J, Ailon T, Paquette S, Boyd M, Street J, Fisher CG, Dvorak MF, Borchers CH, Foster LJ, Kwon BK.

J Neurotrauma. 2017 Jun 15;34(12):2054-2068. doi: 10.1089/neu.2016.4879. Epub 2017 Apr 7.

PMID:
28276985
49.

Bead-Extractor Assisted Ready-to-Use Reagent System (BEARS) for Immunoprecipitation Coupled to MALDI-MS.

Li H, Popp R, Chen M, MacNamara EM, Juncker D, Borchers CH.

Anal Chem. 2017 Apr 4;89(7):3834-3839. doi: 10.1021/acs.analchem.6b04169. Epub 2017 Mar 16.

PMID:
28257572
50.

New Guidelines for Publication of Manuscripts Describing Development and Application of Targeted Mass Spectrometry Measurements of Peptides and Proteins.

Abbatiello S, Ackermann BL, Borchers C, Bradshaw RA, Carr SA, Chalkley R, Choi M, Deutsch E, Domon B, Hoofnagle AN, Keshishian H, Kuhn E, Liebler DC, MacCoss M, MacLean B, Mani DR, Neubert H, Smith D, Vitek O, Zimmerman L.

Mol Cell Proteomics. 2017 Mar;16(3):327-328. doi: 10.1074/mcp.E117.067801. Epub 2017 Feb 9. No abstract available.

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