Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66

1.

Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial.

Groeneveld GH, van der Reyden TJ, Joosten SA, Bootsma HJ, Cobbaert CM, de Vries JJC, Kuijper EJ, van Dissel JT.

J Antimicrob Chemother. 2019 May 18. pii: dkz207. doi: 10.1093/jac/dkz207. [Epub ahead of print]

PMID:
31106377
2.

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.

Lees JA, Ferwerda B, Kremer PHC, Wheeler NE, Serón MV, Croucher NJ, Gladstone RA, Bootsma HJ, Rots NY, Wijmega-Monsuur AJ, Sanders EAM, Trzciński K, Wyllie AL, Zwinderman AH, van den Berg LH, van Rheenen W, Veldink JH, Harboe ZB, Lundbo LF, de Groot LCPGM, van Schoor NM, van der Velde N, Ängquist LH, Sørensen TIA, Nohr EA, Mentzer AJ, Mills TC, Knight JC, du Plessis M, Nzenze S, Weiser JN, Parkhill J, Madhi S, Benfield T, von Gottberg A, van der Ende A, Brouwer MC, Barrett JC, Bentley SD, van de Beek D.

Nat Commun. 2019 May 15;10(1):2176. doi: 10.1038/s41467-019-09976-3.

3.

Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries.

Yahiaoui RY, Bootsma HJ, den Heijer CDJ, Pluister GN, John Paget W, Spreeuwenberg P, Trzcinski K, Stobberingh EE.

BMC Infect Dis. 2018 Aug 29;18(1):440. doi: 10.1186/s12879-018-3341-0.

4.

The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.

Cremers AJH, Mobegi FM, van der Gaast-de Jongh C, van Weert M, van Opzeeland FJ, Vehkala M, Knol MJ, Bootsma HJ, Välimäki N, Croucher NJ, Meis JF, Bentley S, van Hijum SAFT, Corander J, Zomer AL, Ferwerda G, de Jonge MI.

Clin Infect Dis. 2019 Jan 1;68(1):61-69. doi: 10.1093/cid/ciy417.

PMID:
29788414
5.

Adaptation of Bordetella pertussis to the Respiratory Tract.

van Beek LF, de Gouw D, Eleveld MJ, Bootsma HJ, de Jonge MI, Mooi FR, Zomer A, Diavatopoulos DA.

J Infect Dis. 2018 May 25;217(12):1987-1996. doi: 10.1093/infdis/jiy125.

PMID:
29528444
6.

Detection and epidemiology of carbapenemase producing Enterobacteriaceae in the Netherlands in 2013-2014.

Vlek AL, Frentz D, Haenen A, Bootsma HJ, Notermans DW, Frakking FN, de Greeff SC, Leenstra T; ISIS-AR study group.

Eur J Clin Microbiol Infect Dis. 2016 Jul;35(7):1089-96. doi: 10.1007/s10096-016-2636-6. Epub 2016 Apr 28.

PMID:
27126332
7.

Fine-tuning of choline metabolism is important for pneumococcal colonization.

Johnston C, Hauser C, Hermans PW, Martin B, Polard P, Bootsma HJ, Claverys JP.

Mol Microbiol. 2016 Jun;100(6):972-88. doi: 10.1111/mmi.13360. Epub 2016 Apr 6.

8.

Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution.

Earl JP, de Vries SP, Ahmed A, Powell E, Schultz MP, Hermans PW, Hill DJ, Zhou Z, Constantinidou CI, Hu FZ, Bootsma HJ, Ehrlich GD.

Genome Biol Evol. 2016 Apr 6;8(4):955-74. doi: 10.1093/gbe/evw039.

9.

Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice.

van der Maten E, van Selm S, Langereis JD, Bootsma HJ, van Opzeeland FJ, de Groot R, de Jonge MI, van der Flier M.

PLoS One. 2016 Feb 12;11(2):e0149307. doi: 10.1371/journal.pone.0149307. eCollection 2016.

10.

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

van der Maten E, Westra D, van Selm S, Langereis JD, Bootsma HJ, van Opzeeland FJ, de Groot R, Ruseva MM, Pickering MC, van den Heuvel LP, van de Kar NC, de Jonge MI, van der Flier M.

J Infect Dis. 2016 Jun 1;213(11):1820-7. doi: 10.1093/infdis/jiw029. Epub 2016 Jan 21.

11.

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

Hommes TJ, van Lieshout MH, van 't Veer C, Florquin S, Bootsma HJ, Hermans PW, de Vos AF, van der Poll T.

PLoS One. 2015 Dec 16;10(12):e0145138. doi: 10.1371/journal.pone.0145138. eCollection 2015.

12.

Differential gene expression of Moraxella catarrhalis upon exposure to human serum.

de Vries SP, Bootsma HJ.

Genom Data. 2014 Oct 2;2:312-3. doi: 10.1016/j.gdata.2014.09.008. eCollection 2014 Dec.

13.

Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.

Johnston C, Bootsma HJ, Aldridge C, Manuse S, Gisch N, Schwudke D, Hermans PW, Grangeasse C, Polard P, Vollmer W, Claverys JP.

PLoS One. 2015 Apr 22;10(4):e0123702. doi: 10.1371/journal.pone.0123702. eCollection 2015.

14.

Next-generation sequencing of carbapenem-resistant Gram-negative microorganisms: a key tool for surveillance and infection control.

Bootsma HJ, Schouls LM.

Future Microbiol. 2015;10(3):299-302. doi: 10.2217/fmb.14.134. No abstract available.

15.

The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.

van der Zwaluw K, de Haan A, Pluister GN, Bootsma HJ, de Neeling AJ, Schouls LM.

PLoS One. 2015 Mar 23;10(3):e0123690. doi: 10.1371/journal.pone.0123690. eCollection 2015.

16.

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

de Vos AF, Dessing MC, Lammers AJ, de Porto AP, Florquin S, de Boer OJ, de Beer R, Terpstra S, Bootsma HJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2015 Feb 20;10(2):e0118181. doi: 10.1371/journal.pone.0118181. eCollection 2015.

17.

From microbial gene essentiality to novel antimicrobial drug targets.

Mobegi FM, van Hijum SA, Burghout P, Bootsma HJ, de Vries SP, van der Gaast-de Jongh CE, Simonetti E, Langereis JD, Hermans PW, de Jonge MI, Zomer A.

BMC Genomics. 2014 Nov 5;15:958. doi: 10.1186/1471-2164-15-958.

18.

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

Tavares DA, Simões AS, Bootsma HJ, Hermans PW, de Lencastre H, Sá-Leão R.

BMC Genomics. 2014 Oct 6;15:863. doi: 10.1186/1471-2164-15-863.

19.

Genome-wide identification of genes essential for the survival of Streptococcus pneumoniae in human saliva.

Verhagen LM, de Jonge MI, Burghout P, Schraa K, Spagnuolo L, Mennens S, Eleveld MJ, van der Gaast-de Jongh CE, Zomer A, Hermans PW, Bootsma HJ.

PLoS One. 2014 Feb 25;9(2):e89541. doi: 10.1371/journal.pone.0089541. eCollection 2014.

20.

Differentially expressed genes in Bordetella pertussis strains belonging to a lineage which recently spread globally.

de Gouw D, Hermans PW, Bootsma HJ, Zomer A, Heuvelman K, Diavatopoulos DA, Mooi FR.

PLoS One. 2014 Jan 8;9(1):e84523. doi: 10.1371/journal.pone.0084523. eCollection 2014. Erratum in: PLoS One. 2014;9(1). doi: 10.1371/annotation/1b2cfe52-aaea-4148-aa72-a74c78550192.

21.

Deciphering the genetic basis of Moraxella catarrhalis complement resistance: a critical role for the disulphide bond formation system.

de Vries SP, Rademakers RJ, van der Gaast-de Jongh CE, Eleveld MJ, Hermans PW, Bootsma HJ.

Mol Microbiol. 2014 Feb;91(3):522-37. doi: 10.1111/mmi.12475. Epub 2013 Dec 18.

22.

Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.

de Stoppelaar SF, Bootsma HJ, Zomer A, Roelofs JJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2013 Nov 11;8(11):e80062. doi: 10.1371/journal.pone.0080062. eCollection 2013.

23.

Natural genetic transformation generates a population of merodiploids in Streptococcus pneumoniae.

Johnston C, Caymaris S, Zomer A, Bootsma HJ, Prudhomme M, Granadel C, Hermans PW, Polard P, Martin B, Claverys JP.

PLoS Genet. 2013;9(9):e1003819. doi: 10.1371/journal.pgen.1003819. Epub 2013 Sep 26.

24.

Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells.

de Vries SP, Eleveld MJ, Hermans PW, Bootsma HJ.

PLoS One. 2013 Aug 6;8(8):e72193. doi: 10.1371/journal.pone.0072193. Print 2013.

25.

Genome sequence of Moraxella catarrhalis RH4, an isolate of seroresistant lineage.

Zomer A, de Vries SP, Riesbeck K, Meinke AL, Hermans PW, Bootsma HJ.

J Bacteriol. 2012 Dec;194(24):6969. doi: 10.1128/JB.01833-12.

26.

Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.

de Vries SP, Burghout P, Langereis JD, Zomer A, Hermans PW, Bootsma HJ.

Mol Microbiol. 2013 Jan;87(1):14-29. doi: 10.1111/mmi.12081. Epub 2012 Nov 19.

27.

Nonencapsulated Streptococcus pneumoniae resists extracellular human neutrophil elastase- and cathepsin G-mediated killing.

van der Windt D, Bootsma HJ, Burghout P, van der Gaast-de Jongh CE, Hermans PW, van der Flier M.

FEMS Immunol Med Microbiol. 2012 Dec;66(3):445-8. doi: 10.1111/j.1574-695X.2012.01028.x. Epub 2012 Sep 24.

28.

ESSENTIALS: software for rapid analysis of high throughput transposon insertion sequencing data.

Zomer A, Burghout P, Bootsma HJ, Hermans PW, van Hijum SA.

PLoS One. 2012;7(8):e43012. doi: 10.1371/journal.pone.0043012. Epub 2012 Aug 10.

29.

Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media.

Langereis JD, Stol K, Schweda EK, Twelkmeyer B, Bootsma HJ, de Vries SP, Burghout P, Diavatopoulos DA, Hermans PW.

MBio. 2012 Jul 3;3(4):e00079-12. doi: 10.1128/mBio.00079-12. Print 2012.

30.

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates.

Salter SJ, Hinds J, Gould KA, Lambertsen L, Hanage WP, Antonio M, Turner P, Hermans PW, Bootsma HJ, O'Brien KL, Bentley SD.

Microbiology. 2012 Jun;158(Pt 6):1560-9. doi: 10.1099/mic.0.056580-0. Epub 2012 Mar 8.

31.

Two DHH subfamily 1 proteins contribute to pneumococcal virulence and confer protection against pneumococcal disease.

Cron LE, Stol K, Burghout P, van Selm S, Simonetti ER, Bootsma HJ, Hermans PW.

Infect Immun. 2011 Sep;79(9):3697-710. doi: 10.1128/IAI.01383-10. Epub 2011 Jul 18. Erratum in: Infect Immun. 2012 Aug;80(8):2974.

32.

Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule.

Lammers AJ, de Porto AP, Florquin S, de Boer OJ, Bootsma HJ, Hermans PW, van der Poll T.

Immunobiology. 2011 Aug;216(8):863-70. doi: 10.1016/j.imbio.2011.02.004. Epub 2011 Feb 22.

PMID:
21397979
33.

Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates.

Davie JJ, Earl J, de Vries SP, Ahmed A, Hu FZ, Bootsma HJ, Stol K, Hermans PW, Wadowsky RM, Ehrlich GD, Hays JP, Campagnari AA.

BMC Genomics. 2011 Jan 26;12:70. doi: 10.1186/1471-2164-12-70.

34.

Pertussis: a matter of immune modulation.

de Gouw D, Diavatopoulos DA, Bootsma HJ, Hermans PW, Mooi FR.

FEMS Microbiol Rev. 2011 May;35(3):441-74. doi: 10.1111/j.1574-6976.2010.00257.x. Epub 2011 Jan 5. Review.

35.

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells.

Schaar V, de Vries SP, Perez Vidakovics ML, Bootsma HJ, Larsson L, Hermans PW, Bjartell A, Mörgelin M, Riesbeck K.

Cell Microbiol. 2011 Mar;13(3):432-49. doi: 10.1111/j.1462-5822.2010.01546.x. Epub 2010 Nov 24.

PMID:
21044239
36.

Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis.

Molzen TE, Burghout P, Bootsma HJ, Brandt CT, van der Gaast-de Jongh CE, Eleveld MJ, Verbeek MM, Frimodt-Møller N, Østergaard C, Hermans PW.

Infect Immun. 2011 Jan;79(1):288-97. doi: 10.1128/IAI.00631-10. Epub 2010 Nov 1.

37.

The global nutritional regulator CodY is an essential protein in the human pathogen Streptococcus pneumoniae.

Caymaris S, Bootsma HJ, Martin B, Hermans PW, Prudhomme M, Claverys JP.

Mol Microbiol. 2010 Oct;78(2):344-60.

PMID:
20979332
38.

Carbonic anhydrase is essential for Streptococcus pneumoniae growth in environmental ambient air.

Burghout P, Cron LE, Gradstedt H, Quintero B, Simonetti E, Bijlsma JJ, Bootsma HJ, Hermans PW.

J Bacteriol. 2010 Aug;192(15):4054-62. doi: 10.1128/JB.00151-10. Epub 2010 Jun 4.

39.

Genome analysis of Moraxella catarrhalis strain BBH18, [corrected] a human respiratory tract pathogen.

de Vries SP, van Hijum SA, Schueler W, Riesbeck K, Hays JP, Hermans PW, Bootsma HJ.

J Bacteriol. 2010 Jul;192(14):3574-83. doi: 10.1128/JB.00121-10. Epub 2010 May 7. Erratum in: J Bacteriol. 2012 Dec;194(24):7021.

40.

Phenotypic and genomic characterization of pneumococcus-like streptococci isolated from HIV-seropositive patients.

Leegaard TM, Bootsma HJ, Caugant DA, Eleveld MJ, Mannsåker T, Frøholm LO, Gaustad P, Høiby EA, Hermans PW.

Microbiology. 2010 Mar;156(Pt 3):838-48. doi: 10.1099/mic.0.035345-0. Epub 2009 Dec 3.

PMID:
19959577
41.

Highly penicillin-resistant multidrug-resistant pneumococcus-like strains colonizing children in Oeiras, Portugal: genomic characteristics and implications for surveillance.

Simões AS, Sá-Leão R, Eleveld MJ, Tavares DA, Carriço JA, Bootsma HJ, Hermans PW.

J Clin Microbiol. 2010 Jan;48(1):238-46. doi: 10.1128/JCM.01313-09. Epub 2009 Nov 11.

42.

Development of a non-invasive murine infection model for acute otitis media.

Stol K, van Selm S, van den Berg S, Bootsma HJ, Blokx WA, Graamans K, Tonnaer EL, Hermans PW.

Microbiology. 2009 Dec;155(Pt 12):4135-44. doi: 10.1099/mic.0.033175-0. Epub 2009 Sep 17.

PMID:
19762437
43.

Molecular aspects of Moraxella catarrhalis pathogenesis.

de Vries SP, Bootsma HJ, Hays JP, Hermans PW.

Microbiol Mol Biol Rev. 2009 Sep;73(3):389-406, Table of Contents. doi: 10.1128/MMBR.00007-09. Review. Erratum in: Microbiol Mol Biol Rev. 2009 Dec;73(4):809.

44.

Surface-associated lipoprotein PpmA of Streptococcus pneumoniae is involved in colonization in a strain-specific manner.

Cron LE, Bootsma HJ, Noske N, Burghout P, Hammerschmidt S, Hermans PW.

Microbiology. 2009 Jul;155(Pt 7):2401-10. doi: 10.1099/mic.0.026765-0. Epub 2009 Apr 23.

PMID:
19389773
45.

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.

Hendriksen WT, Bootsma HJ, van Diepen A, Estevão S, Kuipers OP, de Groot R, Hermans PW.

Microbiology. 2009 May;155(Pt 5):1569-79. doi: 10.1099/mic.0.025072-0. Epub 2009 Apr 16.

PMID:
19372167
46.

Benzyl alcohol and ethanol can enhance the pathogenic potential of clinical Staphylococcus epidermidis strains.

Milisavljevic V, Tran LP, Batmalle C, Bootsma HJ.

Am J Infect Control. 2008 Oct;36(8):552-8. doi: 10.1016/j.ajic.2007.10.025.

PMID:
18926307
47.

Site-specific contributions of glutamine-dependent regulator GlnR and GlnR-regulated genes to virulence of Streptococcus pneumoniae.

Hendriksen WT, Kloosterman TG, Bootsma HJ, Estevão S, de Groot R, Kuipers OP, Hermans PW.

Infect Immun. 2008 Mar;76(3):1230-8. doi: 10.1128/IAI.01004-07. Epub 2008 Jan 3.

48.

CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization.

Hendriksen WT, Bootsma HJ, Estevão S, Hoogenboezem T, de Jong A, de Groot R, Kuipers OP, Hermans PW.

J Bacteriol. 2008 Jan;190(2):590-601. Epub 2007 Nov 16.

50.

Search for genes essential for pneumococcal transformation: the RADA DNA repair protein plays a role in genomic recombination of donor DNA.

Burghout P, Bootsma HJ, Kloosterman TG, Bijlsma JJ, de Jongh CE, Kuipers OP, Hermans PW.

J Bacteriol. 2007 Sep;189(18):6540-50. Epub 2007 Jul 13.

Supplemental Content

Loading ...
Support Center