Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 69

1.

Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.

Liu J, Kuipers EN, Sips HCM, Dorleijn JC, van Dam AD, Christodoulides C, Karpe F, Zhou G, Boon MR, Rensen PCN, de Vries AAF, Kooijman S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug 26:158511. doi: 10.1016/j.bbalip.2019.08.007. [Epub ahead of print]

2.

Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes.

Janssen LGM, Jauhiainen M, Olkkonen VM, Haridas PAN, Nahon KJ, Rensen PCN, Boon MR.

J Clin Med. 2019 Aug 14;8(8). pii: E1214. doi: 10.3390/jcm8081214.

3.

A single day of high fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice.

Kuipers EN, Held NM, In Het Panhuis W, Modder M, Ruppert PMM, Kersten S, Kooijman S, Guigas B, Houtkooper RH, Rensen PCN, Boon MR.

Am J Physiol Endocrinol Metab. 2019 Aug 6. doi: 10.1152/ajpendo.00123.2019. [Epub ahead of print]

PMID:
31386566
4.

Distribution of Brown Adipose Tissue Radiodensity in Young Adults: Implications for Cold [18F]FDG-PET/CT Analyses.

Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Mol Imaging Biol. 2019 May 30. doi: 10.1007/s11307-019-01381-y. [Epub ahead of print]

PMID:
31147900
5.

Supraclavicular skin temperature measured by iButtons and 18F-fluorodeoxyglucose uptake by brown adipose tissue in adults.

Martinez-Tellez B, Garcia-Rivero Y, Sanchez-Delgado G, Xu H, Amaro-Gahete FJ, Acosta FM, Rensen PCN, Boon MR, Llamas-Elvira JM, Ruiz JR.

J Therm Biol. 2019 May;82:178-185. doi: 10.1016/j.jtherbio.2019.04.006. Epub 2019 Apr 16.

6.

The Mediating Role of Brown Fat and Skeletal Muscle Measured by 18 F-Fluorodeoxyglucose in the Thermoregulatory System in Young Adults.

Martinez-Tellez B, Adelantado-Renau M, Acosta FM, Sanchez-Delgado G, Martinez-Nicolas A, Boon MR, Llamas-Elvira JM, Martinez-Vizcaino V, Ruiz JR.

Obesity (Silver Spring). 2019 Jun;27(6):963-970. doi: 10.1002/oby.22461. Epub 2019 Apr 21.

7.

High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.

Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR.

Front Physiol. 2019 Jan 10;9:1913. doi: 10.3389/fphys.2018.01913. eCollection 2018.

8.

Effect of L-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study.

Boon MR, Hanssen MJW, Brans B, Hülsman CJM, Hoeks J, Nahon KJ, Bakker C, van Klinken JB, Havekes B, Schaart G, Jazet IM, Rensen PCN, van Marken Lichtenbelt WD.

Diabetologia. 2019 Jan;62(1):112-122. doi: 10.1007/s00125-018-4752-6. Epub 2018 Oct 30.

9.

Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice.

Koorneef LL, van den Heuvel JK, Kroon J, Boon MR, 't Hoen PAC, Hettne KM, van de Velde NM, Kolenbrander KB, Streefland TCM, Mol IM, Sips HCM, Kielbasa SM, Mei H, Belanoff JK, Pereira AM, Oosterveer MH, Hunt H, Rensen PCN, Meijer OC.

Endocrinology. 2018 Dec 1;159(12):3925-3936. doi: 10.1210/en.2018-00671.

PMID:
30321321
10.

Effect of sitagliptin on energy metabolism and brown adipose tissue in overweight individuals with prediabetes: a randomised placebo-controlled trial.

Nahon KJ, Doornink F, Straat ME, Botani K, Martinez-Tellez B, Abreu-Vieira G, van Klinken JB, Voortman GJ, Friesema ECH, Ruiz JR, van Velden FHP, de Geus-Oei LF, Smit F, Pereira Arias-Bouda LM, Berbée JFP, Jazet IM, Boon MR, Rensen PCN.

Diabetologia. 2018 Nov;61(11):2386-2397. doi: 10.1007/s00125-018-4716-x. Epub 2018 Aug 25.

11.

IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.

Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2264. doi: 10.3390/ijms19082264.

12.

Gene Expression of Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight.

Nahon KJ, Kantae V, den Haan R, Hanssen MJW, Harms AC, van der Stelt M, Hankemeier T, Jazet IM, van Marken Lichtenbelt WD, Rensen PCN, Boon MR.

Obesity (Silver Spring). 2018 Aug;26(8):1332-1337. doi: 10.1002/oby.22245. Epub 2018 Aug 1.

13.

Role of Human Brown Fat in Obesity, Metabolism and Cardiovascular Disease: Strategies to Turn Up the Heat.

Ruiz JR, Martinez-Tellez B, Sanchez-Delgado G, Osuna-Prieto FJ, Rensen PCN, Boon MR.

Prog Cardiovasc Dis. 2018 Jul - Aug;61(2):232-245. doi: 10.1016/j.pcad.2018.07.002. Epub 2018 Jul 4. Review.

PMID:
29981351
14.

Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.

Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH.

Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3.

15.

Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice.

Kuipers EN, Dam ADV, Held NM, Mol IM, Houtkooper RH, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Jun 16;19(6). pii: E1786. doi: 10.3390/ijms19061786.

16.

The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults.

Martinez-Tellez B, Nahon KJ, Sanchez-Delgado G, Abreu-Vieira G, Llamas-Elvira JM, van Velden FHP, Pereira Arias-Bouda LM, Rensen PCN, Boon MR, Ruiz JR.

Sci Rep. 2018 Jun 4;8(1):8567. doi: 10.1038/s41598-018-26878-4.

17.

Short-term cooling increases serum angiopoietin-like 4 levels in healthy lean men.

Nahon KJ, Hoeke G, Bakker LEH, Jazet IM, Berbée JFP, Kersten S, Rensen PCN, Boon MR.

J Clin Lipidol. 2018 Jan - Feb;12(1):56-61. doi: 10.1016/j.jacl.2017.10.016. Epub 2017 Nov 1.

PMID:
29191670
18.

A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults.

Martinez-Tellez B, Sanchez-Delgado G, Garcia-Rivero Y, Alcantara JMA, Martinez-Avila WD, Muñoz-Hernandez MV, Olza J, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Front Physiol. 2017 Nov 2;8:863. doi: 10.3389/fphys.2017.00863. eCollection 2017.

19.

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.

Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR.

Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26.

PMID:
29121499
20.

Lower critical temperature and cold-induced thermogenesis of lean and overweight humans are inversely related to body mass and basal metabolic rate.

Nahon KJ, Boon MR, Doornink F, Jazet IM, Rensen PCN, Abreu-Vieira G.

J Therm Biol. 2017 Oct;69:238-248. doi: 10.1016/j.jtherbio.2017.08.006. Epub 2017 Aug 12.

PMID:
29037389
21.

South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men.

van Dam AD, Hanssen MJW, van Eenige R, Quinten E, Sips HC, Hülsman CJM, Jazet IM, van Marken Lichtenbelt WD, Ottenhoff THM, Haks MC, Rensen PCN, Boon MR.

Diabetologia. 2017 Dec;60(12):2525-2528. doi: 10.1007/s00125-017-4427-8. Epub 2017 Sep 8. No abstract available.

PMID:
28887664
22.

Differences between the most used equations in BAT-human studies to estimate parameters of skin temperature in young lean men.

Martinez-Tellez B, Sanchez-Delgado G, Acosta FM, Alcantara JMA, Boon MR, Rensen PCN, Ruiz JR.

Sci Rep. 2017 Sep 5;7(1):10530. doi: 10.1038/s41598-017-10444-5.

23.

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V.

Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30.

PMID:
28852207
24.

Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men.

Kantae V, Nahon KJ, Straat ME, Bakker LEH, Harms AC, van der Stelt M, Hankemeier T, Jazet IM, Boon MR, Rensen PCN.

Sci Rep. 2017 Aug 8;7(1):7558. doi: 10.1038/s41598-017-07980-5.

25.

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ.

J Mol Endocrinol. 2017 Oct;59(3):245-255. doi: 10.1530/JME-17-0112. Epub 2017 Jul 10.

PMID:
28694301
26.

Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans.

Hoeke G, Nahon KJ, Bakker LEH, Norkauer SSC, Dinnes DLM, Kockx M, Lichtenstein L, Drettwan D, Reifel-Miller A, Coskun T, Pagel P, Romijn FPHTM, Cobbaert CM, Jazet IM, Martinez LO, Kritharides L, Berbée JFP, Boon MR, Rensen PCN.

J Clin Lipidol. 2017 Jul - Aug;11(4):920-928.e2. doi: 10.1016/j.jacl.2017.04.117. Epub 2017 May 3.

PMID:
28625343
27.

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.

Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J.

Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010.

28.

Targeting white, brown and perivascular adipose tissue in atherosclerosis development.

van Dam AD, Boon MR, Berbée JFP, Rensen PCN, van Harmelen V.

Eur J Pharmacol. 2017 Dec 5;816:82-92. doi: 10.1016/j.ejphar.2017.03.051. Epub 2017 Mar 24. Review.

29.

LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men.

Boon MR, Bakker LEH, Prehn C, Adamski J, Vosselman MJ, Jazet IM, Arias-Bouda LMP, van Lichtenbelt WDM, van Dijk KW, Rensen PCN, Mook-Kanamori DO.

Metabolomics. 2017;13(5):48. doi: 10.1007/s11306-017-1185-z. Epub 2017 Mar 3.

30.

Activation and quantification of human brown adipose tissue: Methodological considerations for between studies comparisons: Comment on: Hot heads & cool bodies: The conundrums of human BAT activity research.

Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Ruiz JR.

Eur J Intern Med. 2017 May;40:e19-e21. doi: 10.1016/j.ejim.2017.02.006. Epub 2017 Feb 16. No abstract available.

PMID:
28215976
31.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

32.

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia.

Marsch E, Demandt JA, Theelen TL, Tullemans BM, Wouters K, Boon MR, van Dijk TH, Gijbels MJ, Dubois LJ, Meex SJ, Mazzone M, Hung G, Fisher EA, Biessen EA, Daemen MJ, Rensen PC, Carmeliet P, Groen AK, Sluimer JC.

Eur Heart J. 2016 Oct 14;37(39):2993-2997. Epub 2016 Apr 28.

33.

HDL functionality in South Asians as compared to white Caucasians.

Bakker LE, Boon MR, Annema W, Dikkers A, van Eyk HJ, Verhoeven A, Mayboroda OA, Jukema JW, Havekes LM, Meinders AE, Willems van Dijk K, Jazet IM, Tietge UJ, Rensen PC.

Nutr Metab Cardiovasc Dis. 2016 Aug;26(8):697-705. doi: 10.1016/j.numecd.2016.02.010. Epub 2016 Feb 19.

PMID:
27052926
34.

Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.

van den Heuvel JK, Boon MR, van Hengel I, Peschier-van der Put E, van Beek L, van Harmelen V, van Dijk KW, Pereira AM, Hunt H, Belanoff JK, Rensen PC, Meijer OC.

Br J Pharmacol. 2016 Jun;173(11):1793-804. doi: 10.1111/bph.13477. Epub 2016 Apr 24.

35.

Role of Brown Fat in Lipoprotein Metabolism and Atherosclerosis.

Hoeke G, Kooijman S, Boon MR, Rensen PC, Berbée JF.

Circ Res. 2016 Jan 8;118(1):173-82. doi: 10.1161/CIRCRESAHA.115.306647. Review.

PMID:
26837747
36.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
37.

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure.

Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S.

Elife. 2015 Oct 17;4. pii: e08428. doi: 10.7554/eLife.08428.

38.

Physiological changes due to mild cooling in healthy lean males of white Caucasian and South Asian descent: A metabolomics study.

Nahon KJ, Boon MR, Bakker LE, Prehn C, Adamski J, Jazet IM, van Dijk KW, Rensen PC, Mook-Kanamori DO.

Arch Biochem Biophys. 2016 Jan 1;589:152-7. doi: 10.1016/j.abb.2015.09.001. Epub 2015 Sep 16.

PMID:
26384768
39.

Cold Exposure Partially Corrects Disturbances in Lipid Metabolism in a Male Mouse Model of Glucocorticoid Excess.

van den Beukel JC, Boon MR, Steenbergen J, Rensen PC, Meijer OC, Themmen AP, Grefhorst A.

Endocrinology. 2015 Nov;156(11):4115-28. doi: 10.1210/en.2015-1092. Epub 2015 Sep 15.

PMID:
26372178
40.

Smoking is associated with increased resting energy expenditure in the general population: The NEO study.

Blauw LL, Boon MR, Rosendaal FR, de Mutsert R, Gast KB, van Dijk KW, Rensen PC, Dekkers OM; NEO study group.

Metabolism. 2015 Nov;64(11):1548-55. doi: 10.1016/j.metabol.2015.08.008. Epub 2015 Aug 18.

PMID:
26363529
41.

Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes.

Liang W, Verschuren L, Mulder P, van der Hoorn JW, Verheij J, van Dam AD, Boon MR, Princen HM, Havekes LM, Kleemann R, van den Hoek AM.

Br J Pharmacol. 2015 Nov;172(22):5293-305. doi: 10.1111/bph.13315. Epub 2015 Oct 22.

42.

Regulation of brown fat by AMP-activated protein kinase.

van Dam AD, Kooijman S, Schilperoort M, Rensen PC, Boon MR.

Trends Mol Med. 2015 Sep;21(9):571-9. doi: 10.1016/j.molmed.2015.07.003. Epub 2015 Aug 10. Review.

PMID:
26271143
43.

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice.

Kooijman S, Wang Y, Parlevliet ET, Boon MR, Edelschaap D, Snaterse G, Pijl H, Romijn JA, Rensen PC.

Diabetologia. 2015 Nov;58(11):2637-46. doi: 10.1007/s00125-015-3727-0. Epub 2015 Aug 9.

44.

Tracing human brown fat.

Boon MR, Nascimento EB, van Marken Lichtenbelt WD.

Nat Med. 2015 Jul;21(7):667-8. doi: 10.1038/nm.3900. No abstract available.

PMID:
26151326
45.

Cold acclimation affects immune composition in skeletal muscle of healthy lean subjects.

van der Lans AA, Boon MR, Haks MC, Quinten E, Schaart G, Ottenhoff TH, van Marken Lichtenbelt WD.

Physiol Rep. 2015 Jul;3(7). pii: e12394. doi: 10.14814/phy2.12394.

46.

Brown Adipose Tissue: A Human Perspective.

Boon MR, van Marken Lichtenbelt WD.

Handb Exp Pharmacol. 2016;233:301-19. doi: 10.1007/164_2015_11. Review.

PMID:
26003832
47.

Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity.

Kooijman S, van den Berg R, Ramkisoensing A, Boon MR, Kuipers EN, Loef M, Zonneveld TC, Lucassen EA, Sips HC, Chatzispyrou IA, Houtkooper RH, Meijer JH, Coomans CP, Biermasz NR, Rensen PC.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6748-53. doi: 10.1073/pnas.1504239112. Epub 2015 May 11.

48.

High prevalence of cardiovascular disease in South Asians: Central role for brown adipose tissue?

Boon MR, Bakker LE, van der Linden RA, van Ouwerkerk AF, de Goeje PL, Counotte J, Jazet IM, Rensen PC.

Crit Rev Clin Lab Sci. 2015;52(3):150-7. doi: 10.3109/10408363.2014.1003634. Epub 2015 May 8. Review.

PMID:
25955567
49.

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.

Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC.

Nat Commun. 2015 Mar 10;6:6356. doi: 10.1038/ncomms7356.

50.

Salsalate activates brown adipose tissue in mice.

van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR.

Diabetes. 2015 May;64(5):1544-54. doi: 10.2337/db14-1125. Epub 2014 Dec 4.

Supplemental Content

Support Center