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Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes.

Janssen LGM, Jauhiainen M, Olkkonen VM, Haridas PAN, Nahon KJ, Rensen PCN, Boon MR.

J Clin Med. 2019 Aug 14;8(8). pii: E1214. doi: 10.3390/jcm8081214.


A single day of high fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice.

Kuipers EN, Held NM, In Het Panhuis W, Modder M, Ruppert PMM, Kersten S, Kooijman S, Guigas B, Houtkooper RH, Rensen PCN, Boon MR.

Am J Physiol Endocrinol Metab. 2019 Aug 6. doi: 10.1152/ajpendo.00123.2019. [Epub ahead of print]


Safety of sugammadex for reversal of neuromuscular block.

Honing G, Martini CH, Bom A, van Velzen M, Niesters M, Aarts L, Dahan A, Boon M.

Expert Opin Drug Saf. 2019 Aug 7:1-9. doi: 10.1080/14740338.2019.1649393. [Epub ahead of print]


Does nociception monitor-guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials.

Meijer FS, Niesters M, van Velzen M, Martini CH, Olofsen E, Edry R, Sessler DI, van Dorp ELA, Dahan A, Boon M.

J Clin Monit Comput. 2019 Jul 20. doi: 10.1007/s10877-019-00362-4. [Epub ahead of print] Review.


Time trends in diagnostic testing for PCD in Europe.

Halbeisen FS, Shoemark A, Barbato A, Boon M, Carr S, Crowley S, Hirst R, Karadag B, Koerner-Rettberg C, Loebinger MR, Lucas JS, Maitre B, Mazurek H, Özçelik U, Martinů V, Schwerk N, Thouvenin G, Tschanz SA, Yiallouros P, Goutaki M, Kuehni CE.

Eur Respir J. 2019 Jul 18. pii: 1900528. doi: 10.1183/13993003.00528-2019. [Epub ahead of print] No abstract available.


Previous Surgery and Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea.

Kezirian EJ, Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose RJ, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen CG, Hsia J, Mehra R, Waters T, Strohl K.

Otolaryngol Head Neck Surg. 2019 Jun 25:194599819856339. doi: 10.1177/0194599819856339. [Epub ahead of print]


Distribution of Brown Adipose Tissue Radiodensity in Young Adults: Implications for Cold [18F]FDG-PET/CT Analyses.

Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Mol Imaging Biol. 2019 May 30. doi: 10.1007/s11307-019-01381-y. [Epub ahead of print]


The Impact of Upper Airway Stimulation on Swallowing Function.

Huntley C, Vasconcellos A, Mullen M, Chou DW, Geosits H, Doghramji K, Boon M.

Ear Nose Throat J. 2019 May 29:145561319853519. doi: 10.1177/0145561319853519. [Epub ahead of print]


Supraclavicular skin temperature measured by iButtons and 18F-fluorodeoxyglucose uptake by brown adipose tissue in adults.

Martinez-Tellez B, Garcia-Rivero Y, Sanchez-Delgado G, Xu H, Amaro-Gahete FJ, Acosta FM, Rensen PCN, Boon MR, Llamas-Elvira JM, Ruiz JR.

J Therm Biol. 2019 May;82:178-185. doi: 10.1016/j.jtherbio.2019.04.006. Epub 2019 Apr 16.


Reversal of Partial Neuromuscular Block and the Ventilatory Response to Hypoxia: A Randomized Controlled Trial in Healthy Volunteers.

Broens SJL, Boon M, Martini CH, Niesters M, van Velzen M, Aarts LPHJ, Dahan A.

Anesthesiology. 2019 Sep;131(3):467-476. doi: 10.1097/ALN.0000000000002711.


Electrophysiological and Psychophysical Studies of Meridional Anisotropies in Children With and Without Astigmatism.

Yap TP, Luu CD, Suttle CM, Chia A, Boon MY.

Invest Ophthalmol Vis Sci. 2019 May 1;60(6):1906-1913. doi: 10.1167/iovs.18-25924.


The Mediating Role of Brown Fat and Skeletal Muscle Measured by 18 F-Fluorodeoxyglucose in the Thermoregulatory System in Young Adults.

Martinez-Tellez B, Adelantado-Renau M, Acosta FM, Sanchez-Delgado G, Martinez-Nicolas A, Boon MR, Llamas-Elvira JM, Martinez-Vizcaino V, Ruiz JR.

Obesity (Silver Spring). 2019 Jun;27(6):963-970. doi: 10.1002/oby.22461. Epub 2019 Apr 21.


Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial.

Stessel B, Boon M, Pelckmans C, Joosten EA, Ory JP, Wyckmans W, Evers S, van Kuijk SMJ, Van de Velde M, Buhre WFFA.

Eur J Anaesthesiol. 2019 May;36(5):351-359. doi: 10.1097/EJA.0000000000000972.


Epistemology for interdisciplinary research - shifting philosophical paradigms of science.

Boon M, Van Baalen S.

Eur J Philos Sci. 2019;9(1):16. doi: 10.1007/s13194-018-0242-4. Epub 2018 Dec 12.


The Relative Contribution of Food Groups to Macronutrient Intake in Children with Cystic Fibrosis: A European Multicenter Assessment.

Calvo-Lerma J, Hulst J, Boon M, Martins T, Ruperto M, Colombo C, Fornés-Ferrer V, Woodcock S, Claes I, Asseiceira I, Garriga M, Bulfamante A, Masip E, Walet S, Crespo P, Valmarana L, Martínez-Barona S, Pereira L, de Boeck K, Ribes-Koninckx C.

J Acad Nutr Diet. 2019 Aug;119(8):1305-1319. doi: 10.1016/j.jand.2019.01.003. Epub 2019 Mar 9.


Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis.

Calvo-Lerma J, Hulst J, Boon M, Colombo C, Masip E, Ruperto M, Fornés-Ferrer V, van der Wiel E, Claes I, Garriga M, Roca M, Crespo-Escobar P, Bulfamante A, Woodcock S, Martínez-Barona S, Andrés A, de Boeck K, Ribes-Koninckx C; MyCyFAPP project.

PLoS One. 2019 Mar 12;14(3):e0213216. doi: 10.1371/journal.pone.0213216. eCollection 2019.


Nociception-guided versus Standard Care during Remifentanil-Propofol Anesthesia: A Randomized Controlled Trial.

Meijer FS, Martini CH, Broens S, Boon M, Niesters M, Aarts L, Olofsen E, van Velzen M, Dahan A.

Anesthesiology. 2019 May;130(5):745-755. doi: 10.1097/ALN.0000000000002634.


Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials.

Lucas JS, Gahleitner F, Amorim A, Boon M, Brown P, Constant C, Cook S, Crowley S, Destouches DMS, Eber E, Mussaffi H, Haarman E, Harris A, Koerner-Rettberg C, Kuehni CE, Latzin P, Loebinger MR, Lorent N, Maitre B, Moreno-Galdó A, Nielsen KG, Özçelik U, Philipsen LKD, Pohunek P, Polverino E, Rademacher J, Robinson P, Snijders D, Yiallouros P, Carr SB.

ERJ Open Res. 2019 Feb 1;5(1). pii: 00147-2018. doi: 10.1183/23120541.00147-2018. eCollection 2019 Feb.


High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.

Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR.

Front Physiol. 2019 Jan 10;9:1913. doi: 10.3389/fphys.2018.01913. eCollection 2018.


Comparison of the TOF-Cuff® monitor with electromyography and acceleromyography during recovery from neuromuscular block.

Krijtenburg P, Honing G, Martini C, Olofsen E, van Elst HJ, Scheffer GJ, Dahan A, Keijzer C, Boon M.

Br J Anaesth. 2019 Feb;122(2):e22-e24. doi: 10.1016/j.bja.2018.11.011. Epub 2018 Dec 10. No abstract available.


PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights.

Johnstone DL, Al-Shekaili HH, Tarailo-Graovac M, Wolf NI, Ivy AS, Demarest S, Roussel Y, Ciapaite J, van Roermund CWT, Kernohan KD, Kosuta C, Ban K, Ito Y, McBride S, Al-Thihli K, Abdelrahim RA, Koul R, Al Futaisi A, Haaxma CA, Olson H, Sigurdardottir LY, Arnold GL, Gerkes EH, Boon M, Heiner-Fokkema MR, Noble S, Bosma M, Jans J, Koolen DA, Kamsteeg EJ, Drögemöller B, Ross CJ, Majewski J, Cho MT, Begtrup A, Wasserman WW, Bui T, Brimble E, Violante S, Houten SM, Wevers RA, van Faassen M, Kema IP, Lepage N; Care4Rare Canada Consortium, Lines MA, Dyment DA, Wanders RJA, Verhoeven-Duif N, Ekker M, Boycott KM, Friedman JM, Pena IA, van Karnebeek CDM.

Brain. 2019 Mar 1;142(3):542-559. doi: 10.1093/brain/awy346.


Interdisciplinary expertise in medical practice: Challenges of using and producing knowledge in complex problem-solving.

Boon M, van Baalen S, Groenier M.

Med Teach. 2019 Jun;41(6):668-677. doi: 10.1080/0142159X.2018.1544417. Epub 2019 Jan 20.


Optimisation of children z-score calculation based on new statistical techniques.

Martinez-Millana A, Hulst JM, Boon M, Witters P, Fernandez-Llatas C, Asseiceira I, Calvo-Lerma J, Basagoiti I, Traver V, De Boeck K, Ribes-Koninckx C.

PLoS One. 2018 Dec 20;13(12):e0208362. doi: 10.1371/journal.pone.0208362. eCollection 2018.


Hypoglossal nerve stimulation in three adults with down syndrome and severe obstructive sleep apnea.

Li C, Boon M, Ishman SL, Suurna MV.

Laryngoscope. 2018 Dec 13. doi: 10.1002/lary.27723. [Epub ahead of print]


Comparing spectacle and toric contact lens prescribing trends for astigmatism.

Chu BS, Boon MY, Noh DH.

Clin Optom (Auckl). 2018 Nov 8;10:119-127. doi: 10.2147/OPTO.S167238. eCollection 2018.


Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ Jr, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R; ADHERE registry investigators.

Eur Respir J. 2019 Jan 3;53(1). pii: 1801405. doi: 10.1183/13993003.01405-2018. Print 2019 Jan.


Functional Analysis and Antivirulence Properties of a New Depolymerase from a Myovirus That Infects Acinetobacter baumannii Capsule K45.

Oliveira H, Costa AR, Ferreira A, Konstantinides N, Santos SB, Boon M, Noben JP, Lavigne R, Azeredo J.

J Virol. 2019 Feb 5;93(4). pii: e01163-18. doi: 10.1128/JVI.01163-18. Print 2019 Feb 15.


Dysfunctional hypoglossal nerve stimulator after electrical cardioversion: A case series.

Vasconcellos AP, Huntley CT, Schell AE, Soose RJ, Boon MS.

Laryngoscope. 2019 Aug;129(8):1949-1953. doi: 10.1002/lary.27488. Epub 2018 Nov 15.


Effect of L-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study.

Boon MR, Hanssen MJW, Brans B, Hülsman CJM, Hoeks J, Nahon KJ, Bakker C, van Klinken JB, Havekes B, Schaart G, Jazet IM, Rensen PCN, van Marken Lichtenbelt WD.

Diabetologia. 2019 Jan;62(1):112-122. doi: 10.1007/s00125-018-4752-6. Epub 2018 Oct 30.


Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice.

Koorneef LL, van den Heuvel JK, Kroon J, Boon MR, 't Hoen PAC, Hettne KM, van de Velde NM, Kolenbrander KB, Streefland TCM, Mol IM, Sips HCM, Kielbasa SM, Mei H, Belanoff JK, Pereira AM, Oosterveer MH, Hunt H, Rensen PCN, Meijer OC.

Endocrinology. 2018 Dec 1;159(12):3925-3936. doi: 10.1210/en.2018-00671.


Cutaneous diphtheria in a returned traveller.

Lim KH, Boon M.

J Paediatr Child Health. 2019 Mar;55(3):358-361. doi: 10.1111/jpc.14245. Epub 2018 Oct 4. No abstract available.


The use of surgical rating scales for the evaluation of surgical working conditions during laparoscopic surgery: a scoping review.

Boon M, Martini CH, Aarts LPHJ, Dahan A.

Surg Endosc. 2019 Jan;33(1):19-25. doi: 10.1007/s00464-018-6424-5. Epub 2018 Sep 14. Review.


Comparing Upper Airway Stimulation to Transoral Robotic Base of Tongue Resection for Treatment of Obstructive Sleep Apnea.

Huntley C, Topf MC, Christopher V, Doghramji K, Curry J, Boon M.

Laryngoscope. 2019 Apr;129(4):1010-1013. doi: 10.1002/lary.27484. Epub 2018 Sep 12.


Larger Than Life: Isolation and Genomic Characterization of a Jumbo Phage That Infects the Bacterial Plant Pathogen, Agrobacterium tumefaciens.

Attai H, Boon M, Phillips K, Noben JP, Lavigne R, Brown PJB.

Front Microbiol. 2018 Aug 14;9:1861. doi: 10.3389/fmicb.2018.01861. eCollection 2018.


Effect of sitagliptin on energy metabolism and brown adipose tissue in overweight individuals with prediabetes: a randomised placebo-controlled trial.

Nahon KJ, Doornink F, Straat ME, Botani K, Martinez-Tellez B, Abreu-Vieira G, van Klinken JB, Voortman GJ, Friesema ECH, Ruiz JR, van Velden FHP, de Geus-Oei LF, Smit F, Pereira Arias-Bouda LM, Berbée JFP, Jazet IM, Boon MR, Rensen PCN.

Diabetologia. 2018 Nov;61(11):2386-2397. doi: 10.1007/s00125-018-4716-x. Epub 2018 Aug 25.


Upper Airway Stimulation in Patients With Obstructive Sleep Apnea and an Elevated Body Mass Index: A Multi-institutional Review.

Huntley C, Steffen A, Doghramji K, Hofauer B, Heiser C, Boon M.

Laryngoscope. 2018 Oct;128(10):2425-2428. doi: 10.1002/lary.27426. Epub 2018 Aug 10.


Predicting Success of Oral Appliance Therapy in Treating Obstructive Sleep Apnea Using Drug-Induced Sleep Endoscopy.

Huntley C, Cooper J, Stiles M, Grewal R, Boon M.

J Clin Sleep Med. 2018 Aug 15;14(8):1333-1337. doi: 10.5664/jcsm.7266.


Upper Airway Stimulation in Patients Who Have Undergone Unsuccessful Prior Palate Surgery: An Initial Evaluation.

Huntley C, Vasconcellos A, Doghramji K, Hofauer B, Heiser C, Boon M.

Otolaryngol Head Neck Surg. 2018 Nov;159(5):938-940. doi: 10.1177/0194599818792191. Epub 2018 Aug 7.


IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.

Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2264. doi: 10.3390/ijms19082264.


Gene Expression of Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight.

Nahon KJ, Kantae V, den Haan R, Hanssen MJW, Harms AC, van der Stelt M, Hankemeier T, Jazet IM, van Marken Lichtenbelt WD, Rensen PCN, Boon MR.

Obesity (Silver Spring). 2018 Aug;26(8):1332-1337. doi: 10.1002/oby.22245. Epub 2018 Aug 1.


Lung function in patients with primary ciliary dyskinesia: an iPCD Cohort study.

Halbeisen FS, Goutaki M, Spycher BD, Amirav I, Behan L, Boon M, Hogg C, Casaulta C, Crowley S, Haarman EG, Karadag B, Koerner-Rettberg C, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Omran H, Santamaria F, Schwerk N, Thouvenin G, Yiallouros P, Lucas JS, Latzin P, Kuehni CE.

Eur Respir J. 2018 Aug 23;52(2). pii: 1801040. doi: 10.1183/13993003.01040-2018. Print 2018 Aug.


Role of Human Brown Fat in Obesity, Metabolism and Cardiovascular Disease: Strategies to Turn Up the Heat.

Ruiz JR, Martinez-Tellez B, Sanchez-Delgado G, Osuna-Prieto FJ, Rensen PCN, Boon MR.

Prog Cardiovasc Dis. 2018 Jul - Aug;61(2):232-245. doi: 10.1016/j.pcad.2018.07.002. Epub 2018 Jul 4. Review.


Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.

Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH.

Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3.


Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice.

Kuipers EN, Dam ADV, Held NM, Mol IM, Houtkooper RH, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Jun 16;19(6). pii: E1786. doi: 10.3390/ijms19061786.


The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults.

Martinez-Tellez B, Nahon KJ, Sanchez-Delgado G, Abreu-Vieira G, Llamas-Elvira JM, van Velden FHP, Pereira Arias-Bouda LM, Rensen PCN, Boon MR, Ruiz JR.

Sci Rep. 2018 Jun 4;8(1):8567. doi: 10.1038/s41598-018-26878-4.


Impact of high- versus low-dose neuromuscular blocking agent administration on unplanned 30-day readmission rates in retroperitoneal laparoscopic surgery.

Boon M, Martini C, Yang HK, Sen SS, Bevers R, Warlé M, Aarts L, Niesters M, Dahan A.

PLoS One. 2018 May 23;13(5):e0197036. doi: 10.1371/journal.pone.0197036. eCollection 2018.


Comparing Upper Airway Stimulation to Expansion Sphincter Pharyngoplasty: A Single University Experience.

Huntley C, Chou DW, Doghramji K, Boon M.

Ann Otol Rhinol Laryngol. 2018 Jun;127(6):379-383. doi: 10.1177/0003489418771395. Epub 2018 Apr 30.


Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium.

Mirabelli C, Jaspers M, Boon M, Jorissen M, Koukni M, Bardiot D, Chaltin P, Marchand A, Neyts J, Jochmans D.

J Antimicrob Chemother. 2018 Jul 1;73(7):1823-1829. doi: 10.1093/jac/dky089.


Incidence and outcome of acquired demyelinating syndromes in Dutch children: update of a nationwide and prospective study.

de Mol CL, Wong YYM, van Pelt ED, Ketelslegers IA, Bakker DP, Boon M, Braun KPJ, van Dijk KGJ, Eikelenboom MJ, Engelen M, Geleijns K, Haaxma CA, Niermeijer JMF, Niks EH, Peeters EAJ, Peeters-Scholte CMPCD, Poll-The BT, Portier RP, de Rijk-van Andel JF, Samijn JPA, Schippers HM, Snoeck IN, Stroink H, Vermeulen RJ, Verrips A, Visscher F, Vles JSH, Willemsen MAAP, Catsman-Berrevoets CE, Hintzen RQ, Neuteboom RF.

J Neurol. 2018 Jun;265(6):1310-1319. doi: 10.1007/s00415-018-8835-6. Epub 2018 Mar 22.


Upper Airway Stimulation for Obstructive Sleep Apnea: Results from the ADHERE Registry.

Boon M, Huntley C, Steffen A, Maurer JT, Sommer JU, Schwab R, Thaler E, Soose R, Chou C, Strollo P, Kezirian EJ, Chia S, Withrow K, Weidenbecher M, Strohl K, Doghramji K, Hofauer B, Heiser C; ADHERE Registry Investigators.

Otolaryngol Head Neck Surg. 2018 Aug;159(2):379-385. doi: 10.1177/0194599818764896. Epub 2018 Mar 20.


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