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Items: 1 to 50 of 456

1.

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.

Galvani E, Mundra PA, Valpione S, Garcia-Martinez P, Smith M, Greenall J, Thakur R, Helmink B, Andrews MC, Boon L, Chester C, Gremel G, Hogan K, Mandal A, Zeng K, Banyard A, Ashton G, Cook M, Lorigan P, Wargo JA, Dhomen N, Marais R.

Nat Commun. 2020 Feb 12;11(1):853. doi: 10.1038/s41467-020-14632-2.

PMID:
32051401
2.

Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells.

McGinley AM, Sutton CE, Edwards SC, Leane CM, DeCourcey J, Teijeiro A, Hamilton JA, Boon L, Djouder N, Mills KHG.

Immunity. 2020 Jan 27. pii: S1074-7613(20)30029-7. doi: 10.1016/j.immuni.2020.01.002. [Epub ahead of print]

PMID:
32023490
3.

Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome.

Ma S, Chee J, Fear VS, Forbes CA, Boon L, Dick IM, Robinson BWS, Creaney J.

Oncoimmunology. 2019 Nov 7;9(1):1684714. doi: 10.1080/2162402X.2019.1684714. eCollection 2020.

4.

Inhibition of the SRC kinase HCK impairs STAT3-dependent gastric tumor growth in mice.

Poh AR, Dwyer AR, Eissmann MF, Chand AL, Baloyan D, Boon L, Murrey MW, Whitehead L, O'Brien M, Lowell CA, Putoczki TL, Pixley FJ, O'Donoghue RJ, Ernst M.

Cancer Immunol Res. 2020 Jan 28. pii: canimm.0623.2019. doi: 10.1158/2326-6066.CIR-19-0623. [Epub ahead of print]

PMID:
31992566
5.

Esthetic evaluation of single implant restorations, adjacent single implant restorations, and implant-supported fixed partial dentures: A 1-year prospective study.

Boon L, De Mars G, Favril C, Duyck J, Quirynen M, Vandamme K.

Clin Implant Dent Relat Res. 2020 Jan 7. doi: 10.1111/cid.12882. [Epub ahead of print]

PMID:
31912661
6.

Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.

Steen-Louws C, Boross P, Prado J, Meeldijk J, Langenhorst JB, Huitema ADR, den Hartog MT, Boon L, Lafeber FPJG, Hack CE, Eijkelkamp N, Popov-Celeketic J.

Pharm Res. 2019 Dec 26;37(2):17. doi: 10.1007/s11095-019-2744-y.

7.

An intrinsic role of IL-33 in Treg cell-mediated tumor immunoevasion.

Hatzioannou A, Banos A, Sakelaropoulos T, Fedonidis C, Vidali MS, Köhne M, Händler K, Boon L, Henriques A, Koliaraki V, Georgiadis P, Zoidakis J, Termentzi A, Beyer M, Chavakis T, Boumpas D, Tsirigos A, Verginis P.

Nat Immunol. 2020 Jan;21(1):75-85. doi: 10.1038/s41590-019-0555-2. Epub 2019 Dec 16.

PMID:
31844326
8.

Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation.

Hoste E, Maueröder C, van Hove L, Catrysse L, Vikkula HK, Sze M, Maes B, Karjosukarso D, Martens L, Gonçalves A, Parthoens E, Roelandt R, Declercq W, Fuentes I, Palisson F, Gonzalez S, Salas-Alanis JC, Boon L, Huebener P, Mulder KW, Ravichandran K, Saeys Y, Schwabe RF, van Loo G.

Cell Rep. 2019 Nov 26;29(9):2689-2701.e4. doi: 10.1016/j.celrep.2019.10.104.

9.

Regulatory Role for NK Cells in a Mouse Model of Systemic Juvenile Idiopathic Arthritis.

Vandenhaute J, Avau A, Filtjens J, Malengier-Devlies B, Imbrechts M, Van den Berghe N, Ahmadzadeh K, Mitera T, Boon L, Leclercq G, Wouters C, Matthys P.

J Immunol. 2019 Dec 15;203(12):3339-3348. doi: 10.4049/jimmunol.1900510. Epub 2019 Nov 1.

PMID:
31676671
10.

Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment.

Aston WJ, Hope DE, Cook AM, Boon L, Dick I, Nowak AK, Lake RA, Lesterhuis WJ.

Oncoimmunology. 2019 Jul 13;8(11):e1641390. doi: 10.1080/2162402X.2019.1641390. eCollection 2019.

11.

A Clinical Feasibility Study to Image Angiogenesis in Patients with Arteriovenous Malformations Using 68Ga-RGD PET/CT.

Lobeek D, Bouwman FCM, Aarntzen EHJG, Molkenboer-Kuenen JDM, Flucke UE, Nguyen HL, Vikkula M, Boon LM, Klein W, Laverman P, Oyen WJG, Boerman OC, Terry SYA, Schultze Kool LJ, Rijpkema M.

J Nucl Med. 2020 Feb;61(2):270-275. doi: 10.2967/jnumed.119.231167. Epub 2019 Sep 13.

PMID:
31519800
12.

A not so harmless mass: Kaposiform hemangioendothelioma complicated by a Kasabach-Merritt phenomenon.

Tribolet S, Hoyoux C, Boon LM, Cheruy C, Demarche M, Jamblin P, Roberti A, Willemaers V, Viellevoye R, Rigo V, Broux I.

Arch Pediatr. 2019 Sep;26(6):365-369. doi: 10.1016/j.arcped.2019.06.003. Epub 2019 Jul 25.

PMID:
31353149
13.

Distance to white matter tracts is associated with deep brain stimulation motor outcome in Parkinson's disease.

Prent N, Potters WV, Boon LI, Caan MWA, de Bie RMA, van den Munckhof P, Schuurman PR, van Rootselaar AF.

J Neurosurg. 2019 Jul 26:1-10. doi: 10.3171/2019.5.JNS1952. [Epub ahead of print]

PMID:
31349226
14.

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment.

Zemek RM, De Jong E, Chin WL, Schuster IS, Fear VS, Casey TH, Forbes C, Dart SJ, Leslie C, Zaitouny A, Small M, Boon L, Forrest ARR, Muiri DO, Degli-Esposti MA, Millward MJ, Nowak AK, Lassmann T, Bosco A, Lake RA, Lesterhuis WJ.

Sci Transl Med. 2019 Jul 17;11(501). pii: eaav7816. doi: 10.1126/scitranslmed.aav7816.

PMID:
31316010
15.

RASA1 mosaic mutations in patients with capillary malformation-arteriovenous malformation.

Revencu N, Fastre E, Ravoet M, Helaers R, Brouillard P, Bisdorff-Bresson A, Chung CWT, Gerard M, Dvorakova V, Irvine AD, Boon LM, Vikkula M.

J Med Genet. 2020 Jan;57(1):48-52. doi: 10.1136/jmedgenet-2019-106024. Epub 2019 Jul 12.

PMID:
31300548
16.

The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF.

Vetters J, van Helden MJ, Wahlen S, Tavernier SJ, Martens A, Fayazpour F, Vergote K, Vanheerswynghels M, Deswarte K, Van Moorleghem J, De Prijck S, Takahashi N, Vandenabeele P, Boon L, van Loo G, Vivier E, Lambrecht BN, Janssens S.

J Exp Med. 2019 Sep 2;216(9):2010-2023. doi: 10.1084/jem.20182164. Epub 2019 Jul 11.

PMID:
31296735
17.

Limitations of neutrophil depletion by anti-Ly6G antibodies in two heterogenic immunological models.

Pollenus E, Malengier-Devlies B, Vandermosten L, Pham TT, Mitera T, Possemiers H, Boon L, Opdenakker G, Matthys P, Van den Steen PE.

Immunol Lett. 2019 Aug;212:30-36. doi: 10.1016/j.imlet.2019.06.006. Epub 2019 Jun 18.

PMID:
31226358
18.

Drooping Eyelid After Vomiting.

de Haan W, Boon L, Foncke EM.

JAMA Neurol. 2019 Jul 1;76(7):862-863. doi: 10.1001/jamaneurol.2019.1417. No abstract available.

PMID:
31157830
19.

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner.

Royzman D, Andreev D, Stich L, Rauh M, Bäuerle T, Ellmann S, Boon L, Kindermann M, Peckert K, Bozec A, Schett G, Steinkasserer A, Zinser E.

Front Immunol. 2019 Apr 2;10:633. doi: 10.3389/fimmu.2019.00633. eCollection 2019.

20.

Non-digestible oligosaccharides scFOS/lcFOS facilitate safe subcutaneous immunotherapy for peanut allergy.

Wagenaar L, van Roest M, Kruijssen LJW, Simons PJ, Boon L, Vonk MM, van Esch BCAM, Knippels LMJ, Garssen J, Pieters RHH, Smit JJ.

Clin Mol Allergy. 2019 Apr 4;17:7. doi: 10.1186/s12948-019-0111-5. eCollection 2019.

21.

Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization.

Bhide Y, Dong W, Gribonika I, Voshart D, Meijerhof T, de Vries-Idema J, Norley S, Guilfoyle K, Skeldon S, Engelhardt OG, Boon L, Christensen D, Lycke N, Huckriede A.

Front Immunol. 2019 Mar 29;10:646. doi: 10.3389/fimmu.2019.00646. eCollection 2019.

22.

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus.

Ugarte-Berzal E, Boon L, Martens E, Rybakin V, Blockmans D, Vandooren J, Proost P, Opdenakker G.

Front Immunol. 2019 Mar 22;10:538. doi: 10.3389/fimmu.2019.00538. eCollection 2019.

23.

Combining conventional therapy with immunotherapy: A risky business?

Coosemans A, Vankerckhoven A, Baert T, Boon L, Ruts H, Riva M, Blagden S, Delforge M, Concin N, Mirza MR, Ledermann JA, du Bois A, Vergote I.

Eur J Cancer. 2019 May;113:41-44. doi: 10.1016/j.ejca.2019.02.014. Epub 2019 Apr 6.

PMID:
30965214
24.

Rapamycin and treatment of venous malformations.

Seront E, Van Damme A, Boon LM, Vikkula M.

Curr Opin Hematol. 2019 May;26(3):185-192. doi: 10.1097/MOH.0000000000000498.

PMID:
30855337
25.

A systematic review of MEG-based studies in Parkinson's disease: The motor system and beyond.

Boon LI, Geraedts VJ, Hillebrand A, Tannemaat MR, Contarino MF, Stam CJ, Berendse HW.

Hum Brain Mapp. 2019 Jun 15;40(9):2827-2848. doi: 10.1002/hbm.24562. Epub 2019 Mar 7. Review.

26.

Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2.

van den Bijgaart RJE, Kroesen M, Wassink M, Brok IC, Kers-Rebel ED, Boon L, Heise T, van Scherpenzeel M, Lefeber DJ, Boltje TJ, den Brok MH, Hoogerbrugge PM, Büll C, Adema GJ.

J Biol Chem. 2019 Mar 22;294(12):4437-4449. doi: 10.1074/jbc.RA118.002763. Epub 2019 Jan 22.

PMID:
30670592
27.

The pro-tumor effect of CD200 expression is not mimicked by agonistic CD200R antibodies.

Pilch Z, Tonecka K, Skorzynski M, Sas Z, Braniewska A, Kryczka T, Boon L, Golab J, Meyaard L, Rygiel TP.

PLoS One. 2019 Jan 17;14(1):e0210796. doi: 10.1371/journal.pone.0210796. eCollection 2019.

28.

Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells.

Van der Borght K, Scott CL, Martens L, Sichien D, Van Isterdael G, Nindl V, Saeys Y, Boon L, Ludewig B, Gillebert TC, Lambrecht BN.

Front Immunol. 2018 Nov 21;9:2714. doi: 10.3389/fimmu.2018.02714. eCollection 2018.

29.

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells.

Karrich JJ, Romera-Hernández M, Papazian N, Veenbergen S, Cornelissen F, Aparicio-Domingo P, Stenhouse FH, Peddie CD, Hoogenboezem RM, den Hollander CWJ, Gaskell T, Medley T, Boon L, Blackburn CC, Withers DR, Samsom JN, Cupedo T.

Eur J Immunol. 2019 Feb;49(2):290-301. doi: 10.1002/eji.201847671. Epub 2018 Dec 14.

30.

CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors.

Bar-Ephraim YE, Koning JJ, Burniol Ruiz E, Konijn T, Mourits VP, Lakeman KA, Boon L, Bögels M, van Maanen JP, Den Haan JMM, van Egmond M, Bouma G, Reijmers RM, Mebius RE.

J Immunol. 2019 Jan 1;202(1):171-182. doi: 10.4049/jimmunol.1701153. Epub 2018 Nov 30.

31.

Neutrophils mitigate the systemic host response during endotoxemia in mice.

van der Meer AJ, Ding C, Hoogendijk AJ, de Vos AF, Boon L, Zeerleder SS, van der Poll T.

Immunology. 2019 Mar;156(3):277-281. doi: 10.1111/imm.13026. Epub 2018 Dec 18.

32.

PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity.

Oldenhove G, Boucquey E, Taquin A, Acolty V, Bonetti L, Ryffel B, Le Bert M, Englebert K, Boon L, Moser M.

Cell Rep. 2018 Nov 20;25(8):2053-2060.e4. doi: 10.1016/j.celrep.2018.10.091.

33.

Gelatinase B/Matrix Metalloproteinase-9 as Innate Immune Effector Molecule in Achalasia.

Furuzawa-Carballeda J, Boon L, Torres-Villalobos G, Romero-Hernández F, Ugarte-Berzal E, Martens E, Vandooren J, Rybakin V, Coss-Adame E, Valdovinos M, Velazquez-Fernández D, Opdenakker G.

Clin Transl Gastroenterol. 2018 Nov 19;9(11):208. doi: 10.1038/s41424-018-0076-6.

34.

Propeptide glycosylation and galectin-3 binding decrease proteolytic activation of human proMMP-9/progelatinase B.

Boon L, Ugarte-Berzal E, Martens E, Vandooren J, Rybakin V, Colau D, Gordon-Alonso M, van der Bruggen P, Stöcker W, Becker-Pauly C, Witters P, Morava E, Jaeken J, Proost P, Opdenakker G.

FEBS J. 2019 Mar;286(5):930-945. doi: 10.1111/febs.14698. Epub 2018 Nov 30.

PMID:
30422384
35.

Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study.

Hammer J, Seront E, Duez S, Dupont S, Van Damme A, Schmitz S, Hoyoux C, Chopinet C, Clapuyt P, Hammer F, Vikkula M, Boon LM.

Orphanet J Rare Dis. 2018 Oct 29;13(1):191. doi: 10.1186/s13023-018-0934-z.

36.

EDTA/gelatin zymography method to identify C1s versus activated MMP-9 in plasma and immune complexes of patients with systemic lupus erythematosus.

Ugarte-Berzal E, Martens E, Boon L, Vandooren J, Blockmans D, Proost P, Opdenakker G.

J Cell Mol Med. 2019 Jan;23(1):576-585. doi: 10.1111/jcmm.13962. Epub 2018 Oct 24.

37.

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines.

Dong W, Bhide Y, Sicca F, Meijerhof T, Guilfoyle K, Engelhardt OG, Boon L, de Haan CAM, Carnell G, Temperton N, de Vries-Idema J, Kelvin D, Huckriede A.

Front Immunol. 2018 Oct 9;9:2312. doi: 10.3389/fimmu.2018.02312. eCollection 2018.

38.

Clinical correlates of quantitative EEG in Parkinson disease: A systematic review.

Geraedts VJ, Boon LI, Marinus J, Gouw AA, van Hilten JJ, Stam CJ, Tannemaat MR, Contarino MF.

Neurology. 2018 Nov 6;91(19):871-883. doi: 10.1212/WNL.0000000000006473. Epub 2018 Oct 5.

PMID:
30291182
39.

Chiral Control in Pentacoordinate Systems: The Case of Organosilicates.

van der Boon LJP, van Gelderen L, de Groot TR, Lutz M, Slootweg JC, Ehlers AW, Lammertsma K.

Inorg Chem. 2018 Oct 15;57(20):12697-12708. doi: 10.1021/acs.inorgchem.8b01861. Epub 2018 Oct 2.

40.

Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.

Ugarte-Berzal E, Berghmans N, Boon L, Martens E, Vandooren J, Cauwe B, Thijs G, Proost P, Van Damme J, Opdenakker G.

PLoS One. 2018 Oct 1;13(10):e0197944. doi: 10.1371/journal.pone.0197944. eCollection 2018.

41.

Angiosarcoma arising from congenital primary lymphedema.

Janssens P, Dekeuleneer V, Van Damme A, Brouillard P, Revencu N, Clapuyt P, Ferreira I, Ballieux F, Vikkula M, Marot L, Baeck M, Boon LM.

Pediatr Dermatol. 2018 Nov;35(6):e382-e388. doi: 10.1111/pde.13664. Epub 2018 Sep 14.

PMID:
30216524
42.

Absence of Surface IgD Does Not Impair Naive B Cell Homeostasis or Memory B Cell Formation in IGHD Haploinsufficient Humans.

Nechvatalova J, Bartol SJW, Chovancova Z, Boon L, Vlkova M, van Zelm MC.

J Immunol. 2018 Oct 1;201(7):1928-1935. doi: 10.4049/jimmunol.1800767. Epub 2018 Aug 24.

43.

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation.

Obieglo K, Schuijs MJ, Ozir-Fazalalikhan A, Otto F, van Wijck Y, Boon L, Lambrecht BN, Taube C, Smits HH.

Parasite Immunol. 2018 Oct;40(10):e12579. doi: 10.1111/pim.12579. Epub 2018 Sep 16.

44.

Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment.

Pilch Z, Tonecka K, Braniewska A, Sas Z, Skorzynski M, Boon L, Golab J, Meyaard L, Rygiel TP.

Cancer Immunol Res. 2018 Aug;6(8):930-940. doi: 10.1158/2326-6066.CIR-17-0454. Epub 2018 Jul 18.

45.

Role of Peptidylarginine Deiminase 4 in Neutrophil Extracellular Trap Formation and Host Defense during Klebsiella pneumoniae-Induced Pneumonia-Derived Sepsis.

Claushuis TAM, van der Donk LEH, Luitse AL, van Veen HA, van der Wel NN, van Vught LA, Roelofs JJTH, de Boer OJ, Lankelma JM, Boon L, de Vos AF, van 't Veer C, van der Poll T.

J Immunol. 2018 Aug 15;201(4):1241-1252. doi: 10.4049/jimmunol.1800314. Epub 2018 Jul 9.

46.

IL-10 Receptor or TGF-β Neutralization Abrogates the Protective Effect of a Specific Nondigestible Oligosaccharide Mixture in Cow-Milk-Allergic Mice.

Kerperien J, Veening-Griffioen D, Wehkamp T, van Esch BCAM, Hofman GA, Cornelissen P, Boon L, Jeurink PV, Garssen J, Knippels LMJ, Willemsen LEM.

J Nutr. 2018 Aug 1;148(8):1372-1379. doi: 10.1093/jn/nxy104.

47.

Mental health in primary care: Integration through in-service training in a South African rural clinic.

Maconick L, Jenkins LS, Fisher H, Petrie A, Boon L, Reuter H.

Afr J Prim Health Care Fam Med. 2018 May 24;10(1):e1-e7. doi: 10.4102/phcfm.v10i1.1660.

48.

Neutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase.

Vandooren J, Goeminne P, Boon L, Ugarte-Berzal E, Rybakin V, Proost P, Abu El-Asrar AM, Opdenakker G.

Front Immunol. 2018 May 28;9:1154. doi: 10.3389/fimmu.2018.01154. eCollection 2018.

49.

Multiple Cutaneous and Mucosal Venous Malformations.

Boon LM, Vikkula M.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020.
2008 Sep 18 [updated 2018 May 17].

50.

Stability of Chimerism in Non-Obese Diabetic Mice Achieved By Rapid T Cell Depletion Is Associated With High Levels of Donor Cells Very Early After Transplant.

Lin J, Chan WFN, Boon L, Anderson CC.

Front Immunol. 2018 Apr 24;9:837. doi: 10.3389/fimmu.2018.00837. eCollection 2018.

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