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Items: 17


KAT5 promotes invasion and metastasis through C-MYC stabilization in ATC.

Wei X, Cai S, Boohaker RJ, Fried J, Li Y, Hu L, Pan Y, Cheng R, Zhang S, Tian Y, Gao M, Xu B.

Endocr Relat Cancer. 2019 Jan 1;26(1):141-151. doi: 10.1530/ERC-18-0193.


Rational design and development of a peptide inhibitor for the PD-1/PD-L1 interaction.

Boohaker RJ, Sambandam V, Segura I, Miller J, Suto M, Xu B.

Cancer Lett. 2018 Oct 10;434:11-21. doi: 10.1016/j.canlet.2018.04.031. Epub 2018 Jun 18.


Induction of Interleukin 10 by Borrelia burgdorferi Is Regulated by the Action of CD14-Dependent p38 Mitogen-Activated Protein Kinase and cAMP-Mediated Chromatin Remodeling.

Sahay B, Bashant K, Nelson NLJ, Patsey RL, Gadila SK, Boohaker R, Verma A, Strle K, Sellati TJ.

Infect Immun. 2018 Mar 22;86(4). pii: e00781-17. doi: 10.1128/IAI.00781-17. Print 2018 Apr.


DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage.

Wakeman TP, Yang A, Dalal NS, Boohaker RJ, Zeng Q, Ding Q, Xu B.

Oncotarget. 2017 Aug 10;8(48):83975-83985. doi: 10.18632/oncotarget.20150. eCollection 2017 Oct 13.


Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.

Zhang W, Zhai L, Lu W, Boohaker RJ, Padmalayam I, Li Y.

Chem Biol Drug Des. 2016 Aug;88(2):178-87. doi: 10.1111/cbdd.12744. Epub 2016 Mar 6.


Discovery of a novel inhibitor of kinesin-like protein KIFC1.

Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y.

Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4.


A radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas.

Liu N, Boohaker RJ, Jiang C, Boohaker JR, Xu B.

Oncotarget. 2015 Oct 27;6(33):34649-57. doi: 10.18632/oncotarget.5299.


KIFC1 is a novel potential therapeutic target for breast cancer.

Li Y, Lu W, Chen D, Boohaker RJ, Zhai L, Padmalayam I, Wennerberg K, Xu B, Zhang W.

Cancer Biol Ther. 2015;16(9):1316-22. doi: 10.1080/15384047.2015.1070980. Epub 2015 Jul 15.


A MicroRNA Expression Signature In Taxane-anthracycline-Based Neoadjuvant Chemotherapy Response.

Zheng Y, Li S, Boohaker RJ, Liu X, Zhu Y, Zhai L, Li H, Gu F, Fan Y, Lang R, Liu F, Qian X, Xu B, Fu L.

J Cancer. 2015 Jun 10;6(7):671-7. doi: 10.7150/jca.11616. eCollection 2015.


The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption.

Lee MW, Bassiouni R, Sparrow NA, Iketani A, Boohaker RJ, Moskowitz C, Vishnubhotla P, Khaled AS, Oyer J, Copik A, Fernandez-Valle C, Perez JM, Khaled AR.

Cell Death Dis. 2014 May 22;5:e1249. doi: 10.1038/cddis.2014.225.


The versatile functions of ATM kinase.

Boohaker RJ, Xu B.

Biomed J. 2014 Jan-Feb;37(1):3-9. doi: 10.4103/2319-4170.125655. Review.


ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity.

Boohaker RJ, Cui X, Stackhouse M, Xu B.

Radiother Oncol. 2013 Sep;108(3):403-8. doi: 10.1016/j.radonc.2013.06.017. Epub 2013 Jul 25.


The use of therapeutic peptides to target and to kill cancer cells.

Boohaker RJ, Lee MW, Vishnubhotla P, Perez JM, Khaled AR.

Curr Med Chem. 2012;19(22):3794-804. Review.


Rational development of a cytotoxic peptide to trigger cell death.

Boohaker RJ, Zhang G, Lee MW, Nemec KN, Santra S, Perez JM, Khaled AR.

Mol Pharm. 2012 Jul 2;9(7):2080-93. doi: 10.1021/mp300167e. Epub 2012 May 29.


BAX supports the mitochondrial network, promoting bioenergetics in nonapoptotic cells.

Boohaker RJ, Zhang G, Carlson AL, Nemec KN, Khaled AR.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1466-78. doi: 10.1152/ajpcell.00325.2010. Epub 2011 Feb 2.


Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729.

Grenier AL, Abu-ihweij K, Zhang G, Ruppert SM, Boohaker R, Slepkov ER, Pridemore K, Ren JJ, Fliegel L, Khaled AR.

Am J Physiol Cell Physiol. 2008 Oct;295(4):C883-96. doi: 10.1152/ajpcell.00574.2007. Epub 2008 Aug 13.


Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment.

Haga CL, Ehrhardt GR, Boohaker RJ, Davis RS, Cooper MD.

Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9770-5. Epub 2007 May 23.

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