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Items: 1 to 50 of 56

1.

Clonally related duodenal-type follicular lymphoma and in situ follicular neoplasia.

Nann D, Bonzheim I, Müller I, Mankel B, Quintanilla-Martínez L, Sipos B, Fend F.

Haematologica. 2019 Aug 1. pii: haematol.2019.226142. doi: 10.3324/haematol.2019.226142. [Epub ahead of print]

2.

Clonal evolution of chronic lymphocytic leukemia to Langerhans cell histiocytosis: a case report.

Frauenfeld L, Bonzheim I, Wirths S, Steinhilber J, Horger M, Mankel B, Bethge W, Fend F, Federmann B.

Virchows Arch. 2019 Jul 17. doi: 10.1007/s00428-019-02608-7. [Epub ahead of print]

PMID:
31317311
3.

Highly sensitive and specific in situ hybridization assay for quantification of SOX11 mRNA in mantle cell lymphoma reveals association of TP53 mutations with negative and low SOX11 expression.

Federmann B, Frauenfeld L, Pertsch H, Borgmann V, Steinhilber J, Bonzheim I, Fend F, Quintanilla-Martinez L.

Haematologica. 2019 Jul 11. pii: haematol.2019.219543. doi: 10.3324/haematol.2019.219543. [Epub ahead of print]

4.

Peripheral T-cell lymphoma NOS arising in patients with classical Hodgkin lymphoma of cytotoxic phenotype.

Huettl KS, Staiger AM, Stehle A, Bonzheim I, Horn H, Borgmann V, Ott M, Fend F, Ott G.

Leuk Lymphoma. 2019 Jul 10:1-4. doi: 10.1080/10428194.2019.1636987. [Epub ahead of print] No abstract available.

PMID:
31290373
5.

Variant classification in precision oncology.

Leichsenring J, Horak P, Kreutzfeldt S, Heining C, Christopoulos P, Volckmar AL, Neumann O, Kirchner M, Ploeger C, Budczies J, Heilig CE, Hutter B, Fröhlich M, Uhrig S, Kazdal D, Allgäuer M, Harms A, Rempel E, Lehmann U, Thomas M, Pfarr N, Azoitei N, Bonzheim I, Marienfeld R, Möller P, Werner M, Fend F, Boerries M, von Bubnoff N, Lassmann S, Longerich T, Bitzer M, Seufferlein T, Malek N, Weichert W, Schirmacher P, Penzel R, Endris V, Brors B, Klauschen F, Glimm H, Fröhling S, Stenzinger A.

Int J Cancer. 2019 Apr 22. doi: 10.1002/ijc.32358. [Epub ahead of print]

PMID:
31008532
6.

The pathological features of angioimmunoblastic T-cell lymphomas with IDH2R172 mutations.

Steinhilber J, Mederake M, Bonzheim I, Serinsöz-Linke E, Müller I, Fallier-Becker P, Lemonnier F, Gaulard P, Fend F, Quintanilla-Martinez L.

Mod Pathol. 2019 Jul;32(8):1123-1134. doi: 10.1038/s41379-019-0254-4. Epub 2019 Apr 5.

PMID:
30952970
7.

Pediatric Langerhans cell histiocytosis: the impact of mutational profile on clinical progression and late sequelae.

Nann D, Schneckenburger P, Steinhilber J, Metzler G, Beschorner R, Schwarze CP, Lang P, Handgretinger R, Fend F, Ebinger M, Bonzheim I.

Ann Hematol. 2019 Jul;98(7):1617-1626. doi: 10.1007/s00277-019-03678-y. Epub 2019 Mar 28.

PMID:
30923995
8.

CREBBP gene mutations are frequently detected in in situ follicular neoplasia.

Schmidt J, Ramis-Zaldivar JE, Bonzheim I, Steinhilber J, Müller I, Haake A, Yu SC, Raffeld M, Fend F, Salaverria I, Siebert R, Jaffe ES, Quintanilla-Martinez L.

Blood. 2018 Dec 20;132(25):2687-2690. doi: 10.1182/blood-2018-03-837039. Epub 2018 Nov 6. No abstract available.

PMID:
30401710
9.

First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications.

Löffler MW, Steinhilber J, Hilke FJ, Haen SP, Bösmüller H, Montes-Mojarro IA, Bonzheim I, Stäbler A, Faust U, Grasshoff U, Königsrainer I, Rammensee HG, Kanz L, Königsrainer A, Beckert S, Riess O, Schroeder C.

BMC Med Genet. 2018 Aug 15;19(1):144. doi: 10.1186/s12881-018-0651-4.

10.

The Pathological Spectrum of Systemic Anaplastic Large Cell Lymphoma (ALCL).

Montes-Mojarro IA, Steinhilber J, Bonzheim I, Quintanilla-Martinez L, Fend F.

Cancers (Basel). 2018 Apr 4;10(4). pii: E107. doi: 10.3390/cancers10040107. Review.

11.

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia.

Kampa-Schittenhelm KM, Vogel W, Bonzheim I, Fend F, Horger M, Kanz L, Soekler M, Schittenhelm MM.

Oncotarget. 2018 Jan 31;9(14):11876-11882. doi: 10.18632/oncotarget.24376. eCollection 2018 Feb 20.

12.

Multicenter validation of cancer gene panel-based next-generation sequencing for translational research and molecular diagnostics.

Hirsch B, Endris V, Lassmann S, Weichert W, Pfarr N, Schirmacher P, Kovaleva V, Werner M, Bonzheim I, Fend F, Sperveslage J, Kaulich K, Zacher A, Reifenberger G, Köhrer K, Stepanow S, Lerke S, Mayr T, Aust DE, Baretton G, Weidner S, Jung A, Kirchner T, Hansmann ML, Burbat L, von der Wall E, Dietel M, Hummel M.

Virchows Arch. 2018 Apr;472(4):557-565. doi: 10.1007/s00428-017-2288-7. Epub 2018 Jan 27.

13.

Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia.

Kosmidis P, Bonzheim I, Dufke C, Colak S, Hentrich T, Schroeder C, Bauer P, Adam P, Fend F.

PLoS One. 2017 Jun 22;12(6):e0178503. doi: 10.1371/journal.pone.0178503. eCollection 2017.

14.

EMMPRIN (CD147) is induced by C/EBPβ and is differentially expressed in ALK+ and ALK- anaplastic large-cell lymphoma.

Schmidt J, Bonzheim I, Steinhilber J, Montes-Mojarro IA, Ortiz-Hidalgo C, Klapper W, Fend F, Quintanilla-Martínez L.

Lab Invest. 2017 Sep;97(9):1095-1102. doi: 10.1038/labinvest.2017.54. Epub 2017 Jun 5.

15.

Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation.

Schmidt J, Ramis-Zaldivar JE, Nadeu F, Gonzalez-Farre B, Navarro A, Egan C, Montes-Mojarro IA, Marafioti T, Cabeçadas J, van der Walt J, Dojcinov S, Rosenwald A, Ott G, Bonzheim I, Fend F, Campo E, Jaffe ES, Salaverria I, Quintanilla-Martinez L.

Blood. 2017 Jul 20;130(3):323-327. doi: 10.1182/blood-2017-03-776278. Epub 2017 May 22.

16.

Generalized palisaded neutrophilic and granulomatous dermatitis-a cutaneous manifestation of chronic myelomonocytic leukemia? A clinical, histopathological, and molecular study of 3 cases.

Federmann B, Bonzheim I, Yazdi AS, Schmidt J, Fend F, Metzler G.

Hum Pathol. 2017 Jun;64:198-206. doi: 10.1016/j.humpath.2017.04.010. Epub 2017 Apr 22.

PMID:
28442268
17.

HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy.

Nelde A, Walz JS, Kowalewski DJ, Schuster H, Wolz OO, Peper JK, Cardona Gloria Y, Langerak AW, Muggen AF, Claus R, Bonzheim I, Fend F, Salih HR, Kanz L, Rammensee HG, Stevanović S, Weber AN.

Oncoimmunology. 2016 Dec 23;6(3):e1219825. doi: 10.1080/2162402X.2016.1219825. eCollection 2017.

18.

Erratum to "Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient".

Löffler MW, Chandran PA, Laske K, Schroeder C, Bonzheim I, Walzer M, Hilke FJ, Trautwein N, Kowalewski DJ, Schuster H, Günder M, Carcamo Yañez VA, Mohr C, Sturm M, Nguyen HP, Riess O, Bauer P, Nahnsen S, Nadalin S, Zieker D, Glatzle J, Thiel K, Schneiderhan-Marra N, Clasen S, Bösmüller H, Fend F, Kohlbacher O, Gouttefangeas C, Stevanović S, Königsrainer A, Rammensee HG.

J Hepatol. 2017 Jan;66(1):252-253. doi: 10.1016/j.jhep.2016.10.021. Epub 2016 Nov 15. No abstract available.

PMID:
27863814
19.

Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient.

Löffler MW, Chandran PA, Laske K, Schroeder C, Bonzheim I, Walzer M, Hilke FJ, Trautwein N, Kowalewski DJ, Schuster H, Günder M, Carcamo Yañez VA, Mohr C, Sturm M, Nguyen HP, Riess O, Bauer P, Nahnsen S, Nadalin S, Zieker D, Glatzle J, Thiel K, Schneiderhan-Marra N, Clasen S, Bösmüller H, Fend F, Kohlbacher O, Gouttefangeas C, Stevanović S, Königsrainer A, Rammensee HG.

J Hepatol. 2016 Oct;65(4):849-855. doi: 10.1016/j.jhep.2016.06.027. Epub 2016 Jul 7. Erratum in: J Hepatol. 2017 Jan;66(1):252-253.

20.

ATRX immunostaining predicts IDH and H3F3A status in gliomas.

Ebrahimi A, Skardelly M, Bonzheim I, Ott I, Mühleisen H, Eckert F, Tabatabai G, Schittenhelm J.

Acta Neuropathol Commun. 2016 Jun 16;4(1):60. doi: 10.1186/s40478-016-0331-6.

21.

Genome-wide analysis of pediatric-type follicular lymphoma reveals low genetic complexity and recurrent alterations of TNFRSF14 gene.

Schmidt J, Gong S, Marafioti T, Mankel B, Gonzalez-Farre B, Balagué O, Mozos A, Cabeçadas J, van der Walt J, Hoehn D, Rosenwald A, Ott G, Dojcinov S, Egan C, Nadeu F, Ramis-Zaldívar JE, Clot G, Bárcena C, Pérez-Alonso V, Endris V, Penzel R, Lome-Maldonado C, Bonzheim I, Fend F, Campo E, Jaffe ES, Salaverria I, Quintanilla-Martinez L.

Blood. 2016 Aug 25;128(8):1101-11. doi: 10.1182/blood-2016-03-703819. Epub 2016 Jun 2.

22.

EBV-negative aggressive B-cell lymphomas of donor origin after allogeneic hematopoietic stem cell transplantation: a report of three cases.

Federmann B, Bonzheim I, Schittenhelm J, Quintanilla-Martínez L, Mankel B, Vogel W, Faul C, Bethge W, Fend F.

Leuk Lymphoma. 2016 Nov;57(11):2603-11. doi: 10.3109/10428194.2016.1160088. Epub 2016 Apr 6.

PMID:
27049896
23.

Cytokeratin-positive interstitial reticulum cell tumor: recognition of a potential "in situ" pattern.

Bösmüller H, Klenske J, Bonzheim I, Scharpf M, Rieger N, Quintanilla-Fend L, Fend F.

Hum Pathol. 2016 Mar;49:15-21. doi: 10.1016/j.humpath.2015.10.001. Epub 2015 Oct 26.

PMID:
26826404
24.

Neutrophilic leukocytosis in advanced stage polycythemia vera: hematopathologic features and prognostic implications.

Boiocchi L, Gianelli U, Iurlo A, Fend F, Bonzheim I, Cattaneo D, Knowles DM, Orazi A.

Mod Pathol. 2015 Nov;28(11):1448-57. doi: 10.1038/modpathol.2015.100. Epub 2015 Sep 4.

25.

[Differential diagnostic specific skin infiltrates in chronic myelomonocytic leukemia].

Federmann B, Metzler G, Bonzheim I, Fend F.

Pathologe. 2015 Sep;36(5):494-7. doi: 10.1007/s00292-015-0058-3. German.

PMID:
26292933
26.

ALK-positive anaplastic large cell lymphoma: an evolving story.

Bonzheim I, Steinhilber J, Fend F, Lamant L, Quintanilla-Martinez L.

Front Biosci (Schol Ed). 2015 Jun 1;7:248-59. Review.

PMID:
25961700
27.

High frequency of MYD88 mutations in vitreoretinal B-cell lymphoma: a valuable tool to improve diagnostic yield of vitreous aspirates.

Bonzheim I, Giese S, Deuter C, Süsskind D, Zierhut M, Waizel M, Szurman P, Federmann B, Schmidt J, Quintanilla-Martinez L, Coupland SE, Bartz-Schmidt KU, Fend F.

Blood. 2015 Jul 2;126(1):76-9. doi: 10.1182/blood-2015-01-620518. Epub 2015 Apr 21.

28.

CALR-mutated essential thrombocythemia evolving to chronic myeloid leukemia with coexistent CALR mutation and BCR-ABL translocation.

Bonzheim I, Mankel B, Klapthor P, Schmidt J, Hinrichsen T, Wachter O, Fend F, Quintanilla-Martinez L.

Blood. 2015 Apr 2;125(14):2309-11. doi: 10.1182/blood-2014-12-616847. No abstract available.

29.

MYD88 L265P and CXCR4 mutations in lymphoplasmacytic lymphoma identify cases with high disease activity.

Schmidt J, Federmann B, Schindler N, Steinhilber J, Bonzheim I, Fend F, Quintanilla-Martinez L.

Br J Haematol. 2015 Jun;169(6):795-803. doi: 10.1111/bjh.13361. Epub 2015 Mar 29.

PMID:
25819228
30.

Next-generation sequencing identifies deregulation of microRNAs involved in both innate and adaptive immune response in ALK+ ALCL.

Steinhilber J, Bonin M, Walter M, Fend F, Bonzheim I, Quintanilla-Martinez L.

PLoS One. 2015 Feb 17;10(2):e0117780. doi: 10.1371/journal.pone.0117780. eCollection 2015.

31.

The detection of SRSF2 mutations in routinely processed bone marrow biopsies is useful in the diagnosis of chronic myelomonocytic leukemia.

Federmann B, Abele M, Rosero Cuesta DS, Vogel W, Boiocchi L, Kanz L, Quintanilla-Martinez L, Orazi A, Bonzheim I, Fend F.

Hum Pathol. 2014 Dec;45(12):2471-9. doi: 10.1016/j.humpath.2014.08.014. Epub 2014 Sep 7.

PMID:
25305095
32.

[Predictive biomarkers for tumor-relevant signaling pathways in molecular pathology].

Bonzheim I, Fend F.

Pathologe. 2014 Feb;35(1):93-105. doi: 10.1007/s00292-013-1798-6. Review. German.

PMID:
24496994
33.

Increasing genomic and epigenomic complexity in the clonal evolution from in situ to manifest t(14;18)-positive follicular lymphoma.

Schmidt J, Salaverria I, Haake A, Bonzheim I, Adam P, Montes-Moreno S, Piris MA, Fend F, Siebert R, Quintanilla-Martinez L.

Leukemia. 2014 May;28(5):1103-12. doi: 10.1038/leu.2013.307. Epub 2013 Oct 23.

PMID:
24153014
34.

Hydroa vacciniforme-like lymphoma: a chronic EBV+ lymphoproliferative disorder with risk to develop a systemic lymphoma.

Quintanilla-Martinez L, Ridaura C, Nagl F, Sáez-de-Ocariz M, Durán-McKinster C, Ruiz-Maldonado R, Alderete G, Grube P, Lome-Maldonado C, Bonzheim I, Fend F.

Blood. 2013 Oct 31;122(18):3101-10. doi: 10.1182/blood-2013-05-502203. Epub 2013 Aug 27.

35.

Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation.

Bonzheim I, Irmler M, Klier-Richter M, Steinhilber J, Anastasov N, Schäfer S, Adam P, Beckers J, Raffeld M, Fend F, Quintanilla-Martinez L.

PLoS One. 2013 May 31;8(5):e64544. doi: 10.1371/journal.pone.0064544. Print 2013.

36.

The BCL2 E17 and SP66 antibodies discriminate 2 immunophenotypically and genetically distinct subgroups of conventionally BCL2-"negative" grade 1/2 follicular lymphomas.

Adam P, Baumann R, Schmidt J, Bettio S, Weisel K, Bonzheim I, Fend F, Quintanilla-Martínez L.

Hum Pathol. 2013 Sep;44(9):1817-26. doi: 10.1016/j.humpath.2013.02.004. Epub 2013 May 2.

PMID:
23642737
37.

Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR.

Bösmüller H, Fischer A, Pham DL, Fehm T, Capper D, von Deimling A, Bonzheim I, Staebler A, Fend F.

Hum Pathol. 2013 Mar;44(3):329-35. doi: 10.1016/j.humpath.2012.07.010. Epub 2012 Oct 22.

PMID:
23089489
38.

[Bone marrow biopsy: processing and use of molecular techniques].

Quintanilla-Martinez L, Tinguely M, Bonzheim I, Fend F.

Pathologe. 2012 Nov;33(6):481-9. doi: 10.1007/s00292-012-1647-z. Review. German.

PMID:
23085692
39.

Development of monocytosis in patients with primary myelofibrosis indicates an accelerated phase of the disease.

Boiocchi L, Espinal-Witter R, Geyer JT, Steinhilber J, Bonzheim I, Knowles DM, Fend F, Orazi A.

Mod Pathol. 2013 Feb;26(2):204-12. doi: 10.1038/modpathol.2012.165. Epub 2012 Sep 28.

40.

A unique case of follicular lymphoma provides insights to the clonal evolution from follicular lymphoma in situ to manifest follicular lymphoma.

Bonzheim I, Salaverria I, Haake A, Gastl G, Adam P, Siebert R, Fend F, Quintanilla-Martinez L.

Blood. 2011 Sep 22;118(12):3442-4. doi: 10.1182/blood-2011-07-368944. No abstract available.

41.

Epstein-Barr virus-positive diffuse large B-cell lymphomas of the elderly.

Adam P, Bonzheim I, Fend F, Quintanilla-Martínez L.

Adv Anat Pathol. 2011 Sep;18(5):349-55. doi: 10.1097/PAP.0b013e318229bf08. Review.

PMID:
21841405
42.

Intratumoral lymphocyte density in serous ovarian carcinoma is superior to ERCC1 expression for predicting response to platinum-based therapy.

Bösmüller H, Haitchi-Petnehazy S, Webersinke G, Marschon R, Roithmeier F, Stummvoll W, Fehm T, Klier-Richter M, Bonzheim I, Staebler A, Fend F.

Virchows Arch. 2011 Aug;459(2):183-91. doi: 10.1007/s00428-011-1110-1. Epub 2011 Jun 29.

PMID:
21713364
43.

Geographic variation in the prevalence of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly: a comparative analysis of a Mexican and a German population.

Hofscheier A, Ponciano A, Bonzheim I, Adam P, Lome-Maldonado C, Vela T, Cortes E, Ortiz-Hidalgo C, Fend F, Quintanilla-Martinez L.

Mod Pathol. 2011 Aug;24(8):1046-54. doi: 10.1038/modpathol.2011.62. Epub 2011 Apr 15.

44.

Disturbed expression of the T-cell receptor/CD3 complex and associated signaling molecules in CD30+ T-cell lymphoproliferations.

Geissinger E, Sadler P, Roth S, Grieb T, Puppe B, Müller N, Reimer P, Vetter-Kauczok CS, Wenzel J, Bonzheim I, Rüdiger T, Müller-Hermelink HK, Rosenwald A.

Haematologica. 2010 Oct;95(10):1697-704. doi: 10.3324/haematol.2009.021428. Epub 2010 May 29.

45.

C/EBPβ expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway.

Anastasov N, Bonzheim I, Rudelius M, Klier M, Dau T, Angermeier D, Duyster J, Pittaluga S, Fend F, Raffeld M, Quintanilla-Martinez L.

Haematologica. 2010 May;95(5):760-7. doi: 10.3324/haematol.2009.014050. Epub 2009 Dec 16.

46.

Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.

Bonzheim I, Geissinger E, Chuang WY, Roth S, Ströbel P, Marx A, Reimer P, Wilhelm M, Puppe B, Rosenwald A, Müller-Hermelink HK, Rüdiger T.

J Hematop. 2008 Jul;1(1):11-21. doi: 10.1007/s12308-008-0003-y. Epub 2008 Apr 24.

47.

CD52 expression in peripheral T-cell lymphomas determined by combined immunophenotyping using tumor cell specific T-cell receptor antibodies.

Geissinger E, Bonzheim I, Roth S, Rosenwald A, Müller-Hermelink HK, Rüdiger T.

Leuk Lymphoma. 2009 Jun;50(6):1010-6. doi: 10.1080/10428190902926981.

PMID:
19479612
48.

Evaluation of FoxP3 expression in peripheral T-cell lymphoma.

Bonzheim I, Geissinger E, Tinguely M, Roth S, Grieb T, Reimer P, Wilhelm M, Rosenwald A, Müller-Hermelink HK, Rüdiger T.

Am J Clin Pathol. 2008 Oct;130(4):613-9. doi: 10.1309/L65GWEQ803PP6VX1.

49.

[Anaplastic large cell lymphomas lack the expression of T-cell receptor molecules].

Rüdiger T, Bonzheim I, Geissinger E, Roth S, Zettl A, Marx A, Rosenwald A, Müller-Hermelink HK.

Verh Dtsch Ges Pathol. 2005;89:261-6. German.

PMID:
18035700
50.

[Peripheral NK/T-cell lymphoma].

Rüdiger T, Zettl A, Adam P, Bonzheim I, Geissinger E, Müller-Hermelink HK.

Pathologe. 2007 Feb;28(1):55-8. German.

PMID:
17195040

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