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Items: 7

1.

Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration.

Preising MN, Görg B, Friedburg C, Qvartskhava N, Budde BS, Bonus M, Toliat MR, Pfleger C, Altmüller J, Herebian D, Beyer M, Zöllner HJ, Wittsack HJ, Schaper J, Klee D, Zechner U, Nürnberg P, Schipper J, Schnitzler A, Gohlke H, Lorenz B, Häussinger D, Bolz HJ.

FASEB J. 2019 Jul 25:fj201900914RR. doi: 10.1096/fj.201900914RR. [Epub ahead of print]

PMID:
31345061
2.

Isoform-specific Inhibition of N-methyl-D-aspartate Receptors by Bile Salts.

Koch A, Bonus M, Gohlke H, Klöcker N.

Sci Rep. 2019 Jul 11;9(1):10068. doi: 10.1038/s41598-019-46496-y.

3.

Novel Fluorescent Cyclic Nucleotide Derivatives to Study CNG and HCN Channel Function.

Otte M, Schweinitz A, Lelle M, Thon S, Enke U, Yüksel S, Schmauder R, Bonus M, Gohlke H, Benndorf K.

Biophys J. 2019 Jun 18;116(12):2411-2422. doi: 10.1016/j.bpj.2019.05.006. Epub 2019 May 10.

PMID:
31130235
4.

Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5.

Sachs J, Döhl K, Weber A, Bonus M, Ehlers F, Fleischer E, Klinger A, Gohlke H, Pietruszka J, Schmitt L, Teusch N.

Front Pharmacol. 2019 Apr 16;10:400. doi: 10.3389/fphar.2019.00400. eCollection 2019.

5.

FK506 Resistance of Saccharomyces cerevisiae Pdr5 and Candida albicans Cdr1 Involves Mutations in the Transmembrane Domains and Extracellular Loops.

Tanabe K, Bonus M, Tomiyama S, Miyoshi K, Nagi M, Niimi K, Chindamporn A, Gohlke H, Schmitt L, Cannon RD, Niimi M, Lamping E.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01146-18. doi: 10.1128/AAC.01146-18. Print 2019 Jan.

6.

Hydrophobic alkyl chains substituted to the 8-position of cyclic nucleotides enhance activation of CNG and HCN channels by an intricate enthalpy - entropy compensation.

Otte M, Schweinitz A, Bonus M, Enke U, Schumann C, Gohlke H, Benndorf K.

Sci Rep. 2018 Oct 8;8(1):14960. doi: 10.1038/s41598-018-33050-5.

7.

Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants.

Dröge C, Bonus M, Baumann U, Klindt C, Lainka E, Kathemann S, Brinkert F, Grabhorn E, Pfister ED, Wenning D, Fichtner A, Gotthardt DN, Weiss KH, McKiernan P, Puri RD, Verma IC, Kluge S, Gohlke H, Schmitt L, Kubitz R, Häussinger D, Keitel V.

J Hepatol. 2017 Dec;67(6):1253-1264. doi: 10.1016/j.jhep.2017.07.004. Epub 2017 Jul 19.

PMID:
28733223

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