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Items: 1 to 50 of 255

1.

Nomenclature report 2019: major histocompatibility complex genes and alleles of Great and Small Ape and Old and New World monkey species.

de Groot NG, Otting N, Maccari G, Robinson J, Hammond JA, Blancher A, Lafont BAP, Guethlein LA, Wroblewski EE, Marsh SGE, Shiina T, Walter L, Vigilant L, Parham P, O'Connor DH, Bontrop RE.

Immunogenetics. 2019 Oct 17. doi: 10.1007/s00251-019-01132-x. [Epub ahead of print] Review.

PMID:
31624862
2.

Analysis of macaque BTN3A genes and transcripts in the extended MHC: conserved orthologs of human γδ T cell modulators.

de Groot N, Groen R, Orie V, Bruijnesteijn J, de Groot NG, Doxiadis GGM, Bontrop RE.

Immunogenetics. 2019 Sep;71(8-9):545-559. doi: 10.1007/s00251-019-01126-9. Epub 2019 Aug 5.

3.

Extensive Alternative Splicing of KIR Transcripts.

Bruijnesteijn J, van der Wiel MKH, de Groot N, Otting N, de Vos-Rouweler AJM, Lardy NM, de Groot NG, Bontrop RE.

Front Immunol. 2018 Dec 4;9:2846. doi: 10.3389/fimmu.2018.02846. eCollection 2018.

4.

Author Correction: Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous system.

Francescatto M, Lizio M, Philippens I, Pardo LM, Bontrop R, Sakai M, Watanabe S, Itoh M, Hasegawa A, Lassmann T, Severin J, Harshbarger J, Abugessaisa I, Kasukawa T, Carninci P, Hayashizaki Y, Forrest ARR, Kawaji H, Rizzu P, Heutink P.

Sci Data. 2018 Dec 11;5(1):2. doi: 10.1038/s41597-018-0003-4.

5.

Determining Mhc-DRB profiles in wild populations of three congeneric true lemur species by noninvasive methods.

de Winter II, Qurkhuli T, de Groot N, de Vos-Rouweler AJM, van Hooft P, Heitkönig IMA, Prins HHT, Bontrop RE, Doxiadis GGM.

Immunogenetics. 2019 Feb;71(2):97-107. doi: 10.1007/s00251-018-1085-z. Epub 2018 Oct 15.

6.

Correction to: Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity.

Otting N, de Groot NG, Bontrop RE.

Immunogenetics. 2018 Nov;70(10):689-691. doi: 10.1007/s00251-018-1089-8.

PMID:
30283990
7.

Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity.

Otting N, de Groot NG, Bontrop RE.

Immunogenetics. 2019 Jan;71(1):13-23. doi: 10.1007/s00251-018-1080-4. Epub 2018 Aug 29. Erratum in: Immunogenetics. 2018 Nov;70(10):689-691.

PMID:
30159708
8.

Does the MHC Confer Protection against Malaria in Bonobos?

de Groot NG, Stevens JMG, Bontrop RE.

Trends Immunol. 2018 Oct;39(10):768-771. doi: 10.1016/j.it.2018.07.004. Epub 2018 Aug 17.

PMID:
30126696
9.

Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices.

Böck J, Remmele CW, Dittrich M, Müller T, Kondova I, Persengiev S, Bontrop RE, Ade CP, Kraus TFJ, Giese A, El Hajj N, Schneider E, Haaf T.

Cereb Cortex. 2018 Oct 1;28(10):3724-3739. doi: 10.1093/cercor/bhy180.

10.

Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018.

Ballingall KT, Bontrop RE, Ellis SA, Grimholt U, Hammond JA, Ho CS, Kaufman J, Kennedy LJ, Maccari G, Miller D, Robinson J, Marsh SGE.

Immunogenetics. 2018 Nov;70(10):625-632. doi: 10.1007/s00251-018-1073-3. Epub 2018 Jul 24.

PMID:
30039257
11.

IPD-MHC: nomenclature requirements for the non-human major histocompatibility complex in the next-generation sequencing era.

Maccari G, Robinson J, Bontrop RE, Otting N, de Groot NG, Ho CS, Ballingall KT, Marsh SGE, Hammond JA.

Immunogenetics. 2018 Nov;70(10):619-623. doi: 10.1007/s00251-018-1072-4. Epub 2018 Jul 19.

12.

Nomenclature for the KIR of non-human species.

Robinson J, Guethlein LA, Maccari G, Blokhuis J, Bimber BN, de Groot NG, Sanderson ND, Abi-Rached L, Walter L, Bontrop RE, Hammond JA, Marsh SGE, Parham P.

Immunogenetics. 2018 Sep;70(9):571-583. doi: 10.1007/s00251-018-1064-4. Epub 2018 Jun 4.

13.

MHC class I diversity of olive baboons (Papio anubis) unravelled by next-generation sequencing.

van der Wiel MKH, Doxiadis GGM, de Groot N, Otting N, de Groot NG, Poirier N, Blancho G, Bontrop RE.

Immunogenetics. 2018 Jul;70(7):439-448. doi: 10.1007/s00251-018-1053-7. Epub 2018 Feb 24.

14.

Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes.

Bruijnesteijn J, van der Wiel MKH, Swelsen WTN, Otting N, de Vos-Rouweler AJM, Elferink D, Doxiadis GG, Claas FHJ, Lardy NM, de Groot NG, Bontrop RE.

J Immunol. 2018 Mar 1;200(5):1692-1701. doi: 10.4049/jimmunol.1701480. Epub 2018 Jan 22.

15.

Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous system.

Francescatto M, Lizio M, Philippens I, Pardo LM, Bontrop R, Sakai M, Watanabe S, Itoh M, Hasegawa A, Lassmann T, Severin J, Harshbarger J, Abugessaisa I, Kasukawa T, Carninci P, Hayashizaki Y, Forrest ARR, Kawaji H, Rizzu P, Heutink P.

Sci Data. 2017 Oct 31;4:170163. doi: 10.1038/sdata.2017.163. Erratum in: Sci Data. 2018 Dec 11;5(1):2.

16.

A Specialist Macaque MHC Class I Molecule with HLA-B*27-like Peptide-Binding Characteristics.

de Groot NG, Heijmans CMC, de Ru AH, Janssen GMC, Drijfhout JW, Otting N, Vangenot C, Doxiadis GGM, Koning F, van Veelen PA, Bontrop RE.

J Immunol. 2017 Nov 15;199(10):3679-3690. doi: 10.4049/jimmunol.1700502. Epub 2017 Oct 11.

17.

RNA editing independently occurs at three mir-376a-1 sites and may compromise the stability of the microRNA hairpin.

Gallego A, Hartasánchez DA, Brasó-Vives M, Garcia-Ramallo E, Lopez-Valenzuela M, Baena N, Guitart M, Fernández-Bellon H, Kondova I, Bontrop R, Kawahara Y, Espinosa-Parrilla Y.

Gene. 2017 Sep 10;628:109-116. doi: 10.1016/j.gene.2017.07.032. Epub 2017 Jul 12.

PMID:
28710037
18.

AIDS in chimpanzees: the role of MHC genes.

de Groot NG, Heijmans CMC, Bontrop RE.

Immunogenetics. 2017 Aug;69(8-9):499-509. doi: 10.1007/s00251-017-1006-6. Epub 2017 Jul 10. Review.

PMID:
28695283
19.

Foreword: Immunogenetics special issue 2017.

Bontrop RE.

Immunogenetics. 2017 Aug;69(8-9):479-480. doi: 10.1007/s00251-017-1012-8. No abstract available.

PMID:
28695281
20.

Limited MHC class I intron 2 repertoire variation in bonobos.

de Groot NG, Heijmans CMC, Helsen P, Otting N, Pereboom Z, Stevens JMG, Bontrop RE.

Immunogenetics. 2017 Oct;69(10):677-688. doi: 10.1007/s00251-017-1010-x. Epub 2017 Jun 16.

PMID:
28623393
21.

No postcopulatory selection against MHC-homozygous offspring: Evidence from a pedigreed captive rhesus macaque colony.

Sterck EHM, Bontrop RE, de Groot N, de Vos-Rouweler AJM, Doxiadis GGM.

Mol Ecol. 2017 Jul;26(14):3785-3793. doi: 10.1111/mec.14153. Epub 2017 Jun 21.

PMID:
28437562
22.

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

Guethlein LA, Norman PJ, Heijmans CM, de Groot NG, Hilton HG, Babrzadeh F, Abi-Rached L, Bontrop RE, Parham P.

J Immunol. 2017 Apr 15;198(8):3157-3169. doi: 10.4049/jimmunol.1602163. Epub 2017 Mar 6.

23.

A quick and robust MHC typing method for free-ranging and captive primate species.

de Groot N, Stanbury K, de Vos-Rouweler AJ, de Groot NG, Poirier N, Blancho G, de Luna C, Doxiadis GG, Bontrop RE.

Immunogenetics. 2017 Apr;69(4):231-240. doi: 10.1007/s00251-016-0968-0. Epub 2017 Jan 13.

24.

Major histocompatibility complex haplotyping and long-amplicon allele discovery in cynomolgus macaques from Chinese breeding facilities.

Karl JA, Graham ME, Wiseman RW, Heimbruch KE, Gieger SM, Doxiadis GG, Bontrop RE, O'Connor DH.

Immunogenetics. 2017 Apr;69(4):211-229. doi: 10.1007/s00251-017-0969-7. Epub 2017 Jan 11.

25.

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex.

Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, de Groot NG, Flicek P, Bontrop RE, Hammond JA, Marsh SG.

Nucleic Acids Res. 2017 Jan 4;45(D1):D860-D864. doi: 10.1093/nar/gkw1050. Epub 2016 Nov 28.

26.

Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting.

Sanchez-Delgado M, Court F, Vidal E, Medrano J, Monteagudo-Sánchez A, Martin-Trujillo A, Tayama C, Iglesias-Platas I, Kondova I, Bontrop R, Poo-Llanillo ME, Marques-Bonet T, Nakabayashi K, Simón C, Monk D.

PLoS Genet. 2016 Nov 11;12(11):e1006427. doi: 10.1371/journal.pgen.1006427. eCollection 2016 Nov.

27.

The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species.

Otting N, van der Wiel MK, de Groot N, de Vos-Rouweler AJ, de Groot NG, Doxiadis GG, Wiseman RW, O'Connor DH, Bontrop RE.

Immunogenetics. 2017 Feb;69(2):87-99. doi: 10.1007/s00251-016-0954-6. Epub 2016 Oct 22.

PMID:
27771735
28.

Fifty-one full-length major histocompatibility complex class II alleles in the olive baboon (Papio anubis).

Otting N, van der Wiel MK, Doxiadis GG, Bontrop RE.

HLA. 2016 Nov;88(5):270-271. doi: 10.1111/tan.12906. Epub 2016 Oct 2.

PMID:
27696785
29.

Functional Implications of Human-Specific Changes in Great Ape microRNAs.

Gallego A, Melé M, Balcells I, García-Ramallo E, Torruella-Loran I, Fernández-Bellon H, Abelló T, Kondova I, Bontrop R, Hvilsom C, Navarro A, Marquès-Bonet T, Espinosa-Parrilla Y.

PLoS One. 2016 Apr 22;11(4):e0154194. doi: 10.1371/journal.pone.0154194. eCollection 2016.

30.

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain.

Vermunt MW, Tan SC, Castelijns B, Geeven G, Reinink P, de Bruijn E, Kondova I, Persengiev S; Netherlands Brain Bank, Bontrop R, Cuppen E, de Laat W, Creyghton MP.

Nat Neurosci. 2016 Mar;19(3):494-503. doi: 10.1038/nn.4229. Epub 2016 Jan 25.

PMID:
26807951
31.

Origins of De Novo Genes in Human and Chimpanzee.

Ruiz-Orera J, Hernandez-Rodriguez J, Chiva C, Sabidó E, Kondova I, Bontrop R, Marqués-Bonet T, Albà MM.

PLoS Genet. 2015 Dec 31;11(12):e1005721. doi: 10.1371/journal.pgen.1005721. eCollection 2015 Dec.

32.

Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans.

de Groot NG, Heijmans CM, van der Wiel MK, Blokhuis JH, Mulder A, Guethlein LA, Doxiadis GG, Claas FH, Parham P, Bontrop RE.

J Immunol. 2016 Jan 15;196(2):750-8. doi: 10.4049/jimmunol.1500820. Epub 2015 Dec 18.

33.

Co-evolution of the MHC class I and KIR gene families in rhesus macaques: ancestry and plasticity.

de Groot NG, Blokhuis JH, Otting N, Doxiadis GG, Bontrop RE.

Immunol Rev. 2015 Sep;267(1):228-45. doi: 10.1111/imr.12313. Review.

34.

Novel DRA alleles extracted from seven macaque cohorts.

van der Wiel MK, Otting N, Zeijdel LM, Doxiadis GG, Bontrop RE.

Tissue Antigens. 2015 Feb;85(2):146-8. doi: 10.1111/tan.12510.

35.

High diversity of MIC genes in non-human primates.

Meyer A, Carapito R, Ott L, Radosavljevic M, Georgel P, Adams EJ, Parham P, Bontrop RE, Blancher A, Bahram S.

Immunogenetics. 2014 Oct;66(9-10):581-7. doi: 10.1007/s00251-014-0791-4. Epub 2014 Jul 31.

PMID:
25073428
36.

Differential recombination dynamics within the MHC of macaque species.

de Groot N, Doxiadis GG, Otting N, de Vos-Rouweler AJ, Bontrop RE.

Immunogenetics. 2014 Oct;66(9-10):535-44. doi: 10.1007/s00251-014-0783-4. Epub 2014 Jun 17.

37.

Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees.

Venn O, Turner I, Mathieson I, de Groot N, Bontrop R, McVean G.

Science. 2014 Jun 13;344(6189):1272-5. doi: 10.1126/science.344.6189.1272. Epub 2014 Jun 12.

38.

Strong vaccine-induced CD8 T-cell responses have cytolytic function in a chimpanzee clearing HCV infection.

Verstrepen BE, Verschoor EJ, Fagrouch ZC, Mooij P, de Groot NG, Bontrop RE, Bogers WM, Heeney JL, Koopman G.

PLoS One. 2014 Apr 16;9(4):e95103. doi: 10.1371/journal.pone.0095103. eCollection 2014.

39.

Widespread differences in cortex DNA methylation of the "language gene" CNTNAP2 between humans and chimpanzees.

Schneider E, El Hajj N, Richter S, Roche-Santiago J, Nanda I, Schempp W, Riederer P, Navarro B, Bontrop RE, Kondova I, Scholz CJ, Haaf T.

Epigenetics. 2014 Apr;9(4):533-45. doi: 10.4161/epi.27689. Epub 2014 Jan 16.

40.

Insights on the functional interactions between miRNAs and copy number variations in the aging brain.

Persengiev S, Kondova I, Bontrop R.

Front Mol Neurosci. 2013 Oct 2;6:32. doi: 10.3389/fnmol.2013.00032. Review.

41.

DNA/long peptide vaccination against conserved regions of SIV induces partial protection against SIVmac251 challenge.

Koopman G, Beenhakker N, Nieuwenhuis I, Doxiadis G, Mooij P, Drijfhout JW, Koestler J, Hanke T, Fagrouch Z, Verschoor EJ, Bontrop RE, Wagner R, Bogers WM, Melief CJ.

AIDS. 2013 Nov 28;27(18):2841-51. doi: 10.1097/QAD.0000000000000047.

PMID:
24105029
42.

Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.

de Groot NG, Heijmans CM, de Ru AH, Hassan C, Otting N, Doxiadis GG, Koning F, van Veelen PA, Bontrop RE.

Immunogenetics. 2013 Dec;65(12):897-900. doi: 10.1007/s00251-013-0734-5. Epub 2013 Sep 17.

PMID:
24042460
43.

The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity.

van der Wiel MK, Otting N, de Groot NG, Doxiadis GG, Bontrop RE.

Immunogenetics. 2013 Dec;65(12):841-9. doi: 10.1007/s00251-013-0732-7. Epub 2013 Sep 10.

PMID:
24018468
44.

Evolution and diversity of copy number variation in the great ape lineage.

Sudmant PH, Huddleston J, Catacchio CR, Malig M, Hillier LW, Baker C, Mohajeri K, Kondova I, Bontrop RE, Persengiev S, Antonacci F, Ventura M, Prado-Martinez J; Great Ape Genome Project, Marques-Bonet T, Eichler EE.

Genome Res. 2013 Sep;23(9):1373-82. doi: 10.1101/gr.158543.113. Epub 2013 Jul 3.

45.

Great ape genetic diversity and population history.

Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, Hobolth A, Halager AE, Malig M, Hernandez-Rodriguez J, Hernando-Herraez I, Prüfer K, Pybus M, Johnstone L, Lachmann M, Alkan C, Twigg D, Petit N, Baker C, Hormozdiari F, Fernandez-Callejo M, Dabad M, Wilson ML, Stevison L, Camprubí C, Carvalho T, Ruiz-Herrera A, Vives L, Mele M, Abello T, Kondova I, Bontrop RE, Pusey A, Lankester F, Kiyang JA, Bergl RA, Lonsdorf E, Myers S, Ventura M, Gagneux P, Comas D, Siegismund H, Blanc J, Agueda-Calpena L, Gut M, Fulton L, Tishkoff SA, Mullikin JC, Wilson RK, Gut IG, Gonder MK, Ryder OA, Hahn BH, Navarro A, Akey JM, Bertranpetit J, Reich D, Mailund T, Schierup MH, Hvilsom C, Andrés AM, Wall JD, Bustamante CD, Hammer MF, Eichler EE, Marques-Bonet T.

Nature. 2013 Jul 25;499(7459):471-5. doi: 10.1038/nature12228. Epub 2013 Jul 3.

46.

Haplotype diversity generated by ancient recombination-like events in the MHC of Indian rhesus macaques.

Doxiadis GG, de Groot N, Otting N, de Vos-Rouweler AJ, Bolijn MJ, Heijmans CM, de Groot NG, van der Wiel MK, Remarque EJ, Vangenot C, Nunes JM, Sanchez-Mazas A, Bontrop RE.

Immunogenetics. 2013 Aug;65(8):569-84. doi: 10.1007/s00251-013-0707-8. Epub 2013 May 29.

47.

The HIV-1 pandemic: does the selective sweep in chimpanzees mirror humankind's future?

de Groot NG, Bontrop RE.

Retrovirology. 2013 May 24;10:53. doi: 10.1186/1742-4690-10-53. Review.

48.

Multiple instances of ancient balancing selection shared between humans and chimpanzees.

Leffler EM, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M.

Science. 2013 Mar 29;339(6127):1578-82. doi: 10.1126/science.1234070. Epub 2013 Feb 14.

49.

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

Verstrepen BE, de Groot NG, Groothuismink ZM, Verschoor EJ, de Groen RA, Bogers WM, Janssen HL, Mooij P, Bontrop RE, Koopman G, Boonstra A.

PLoS One. 2012;7(10):e46645. doi: 10.1371/journal.pone.0046645. Epub 2012 Oct 30.

50.

Functional Annotation of Small Noncoding RNAs Target Genes Provides Evidence for a Deregulated Ubiquitin-Proteasome Pathway in Spinocerebellar Ataxia Type 1.

Persengiev S, Kondova I, Bontrop RE.

J Nucleic Acids. 2012;2012:672536. doi: 10.1155/2012/672536. Epub 2012 Oct 3.

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