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Chronic kidney disease in patients with obstructive sleep apnea. A narrative review.

Voulgaris A, Marrone O, Bonsignore MR, Steiropoulos P.

Sleep Med Rev. 2019 Jul 5;47:74-89. doi: 10.1016/j.smrv.2019.07.001. [Epub ahead of print] Review.


Obstructive sleep apnoea in acute coronary syndrome.

Randerath W, Bonsignore MR, Herkenrath S.

Eur Respir Rev. 2019 Jul 31;28(153). pii: 180114. doi: 10.1183/16000617.0114-2018. Print 2019 Sep 30.


Unique sleep-stage transitions determined by obstructive sleep apnea severity, age and gender.

Wächter M, Kantelhardt JW, Bonsignore MR, Bouloukaki I, Escourrou P, Fietze I, Grote L, Korzybski D, Lombardi C, Marrone O, Paranicova I, Pataka A, Ryan S, Schiza SE, Sliwinski P, Steiropoulos P, Verbraecken J, Penzel T; ESADA Study Group.

J Sleep Res. 2019 Jul 25:e12895. doi: 10.1111/jsr.12895. [Epub ahead of print]


Decrease in blood pressure during continuous positive airway pressure treatment for obstructive sleep apnoea: still searching for predictive factors.

Marrone O, Bonsignore MR.

Eur Respir J. 2019 Jul 25;54(1). pii: 1901219. doi: 10.1183/13993003.01219-2019. Print 2019 Jul. No abstract available.


Hyperlipidaemia prevalence and cholesterol control in obstructive sleep apnoea: Data from the European sleep apnea database (ESADA).

Gunduz C, Kacmaz Basoglu O, Hedner J, Bonsignore MR, Hein H, Staats R, Bouloukaki I, Roisman G, Pataka A, Sliwinski P, Ludka O, Pepin JL, Grote L; European Sleep Apnoea Database collaborators.

J Intern Med. 2019 Jul 1. doi: 10.1111/joim.12952. [Epub ahead of print]


Beneficial Effects of CPAP Treatment in High-risk Subgroups of OSA Patients: Some Evidence, at Last.

Bonsignore MR.

EClinicalMedicine. 2018 Sep 15;2-3:9-10. doi: 10.1016/j.eclinm.2018.09.004. eCollection 2018 Aug-Sep. No abstract available.


Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study.

Pataka A, Bonsignore MR, Ryan S, Riha RL, Pepin JL, Schiza S, Basoglu OK, Sliwinski P, Ludka O, Steiropoulos P, Anttalainen U, McNicholas WT, Hedner J, Grote L; ESADA study group.

Eur Respir J. 2019 Jun 20;53(6). pii: 1900091. doi: 10.1183/13993003.00091-2019. Print 2019 Jun. No abstract available.


Comment to the Editorial by KS Park and EW Kang "Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?"

Marrone O, Cibella F, Pépin JL, Grote L, Verbraecken J, Saaresranta T, Kvamme JA, Basoglu OK, Lombardi C, McNicholas WT, Hedner J, Bonsignore MR.

J Thorac Dis. 2019 Mar;11(Suppl 3):S480-S482. doi: 10.21037/jtd.2019.01.93. No abstract available.


Obstructive sleep apnea and comorbidities: a dangerous liaison.

Bonsignore MR, Baiamonte P, Mazzuca E, Castrogiovanni A, Marrone O.

Multidiscip Respir Med. 2019 Feb 14;14:8. doi: 10.1186/s40248-019-0172-9. eCollection 2019. Review.


The European Sleep Apnoea Database (ESADA) ERS Clinical Research Collaboration: past, present and future.

Bonsignore MR, Hedner J; ESADA study group.

Eur Respir J. 2018 Oct 10;52(4). pii: 1801666. doi: 10.1183/13993003.01666-2018. Print 2018 Oct. No abstract available.


Blood-pressure variability in patients with obstructive sleep apnea: current perspectives.

Marrone O, Bonsignore MR.

Nat Sci Sleep. 2018 Aug 21;10:229-242. doi: 10.2147/NSS.S148543. eCollection 2018. Review.


Obstructive sleep apnoea independently predicts lipid levels: Data from the European Sleep Apnea Database.

Gündüz C, Basoglu OK, Hedner J, Zou D, Bonsignore MR, Hein H, Staats R, Pataka A, Barbe F, Sliwinski P, Kent BD, Pepin JL, Grote L; European Sleep Apnea Database Collaborators.

Respirology. 2018 Dec;23(12):1180-1189. doi: 10.1111/resp.13372. Epub 2018 Aug 21.


Clinical presentation of patients with suspected obstructive sleep apnea and self-reported physician-diagnosed asthma in the ESADA cohort.

Bonsignore MR, Pepin JL, Anttalainen U, Schiza SE, Basoglu OK, Pataka A, Steiropoulos P, Dogas Z, Grote L, Hedner J, McNicholas WT, Marrone O; ESADA Study Group.

J Sleep Res. 2018 Dec;27(6):e12729. doi: 10.1111/jsr.12729. Epub 2018 Jul 11.


Challenges and perspectives in obstructive sleep apnoea: Report by an ad hoc working group of the Sleep Disordered Breathing Group of the European Respiratory Society and the European Sleep Research Society.

Randerath W, Bassetti CL, Bonsignore MR, Farre R, Ferini-Strambi L, Grote L, Hedner J, Kohler M, Martinez-Garcia MA, Mihaicuta S, Montserrat J, Pepin JL, Pevernagie D, Pizza F, Polo O, Riha R, Ryan S, Verbraecken J, McNicholas WT.

Eur Respir J. 2018 Sep 16;52(3). pii: 1702616. doi: 10.1183/13993003.02616-2017. Print 2018 Sep. Review.


Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA cohort.

Basoglu OK, Zou D, Tasbakan MS, Hedner J, Ryan S, Verbraecken J, Escourrou P, Antalainen U, Kvamme JA, Bonsignore MR, Schiza S, Grote L; ESADA Study Group.

J Sleep Res. 2018 Dec;27(6):e12705. doi: 10.1111/jsr.12705. Epub 2018 May 24.


Fixed But Not Autoadjusting Positive Airway Pressure Attenuates the Time-dependent Decline in Glomerular Filtration Rate in Patients With OSA.

Marrone O, Cibella F, Pépin JL, Grote L, Verbraecken J, Saaresranta T, Kvamme JA, Basoglu OK, Lombardi C, McNicholas WT, Hedner J, Bonsignore MR; ESADA Network.

Chest. 2018 Aug;154(2):326-334. doi: 10.1016/j.chest.2018.04.020. Epub 2018 Apr 24.


Sleep breathing disorders: have we reached the tipping point?

Suarez-Giron MC, Isetta V, Masa JF, Egea C, Riha RL, Bonsignore MR, Montserrat JM.

ERJ Open Res. 2018 Apr 16;4(2). pii: 00172-2017. doi: 10.1183/23120541.00172-2017. eCollection 2018 Apr.


Obstructive sleep apnea and chronic kidney disease: open questions on a potential public health problem.

Marrone O, Bonsignore MR.

J Thorac Dis. 2018 Jan;10(1):45-48. doi: 10.21037/jtd.2017.12.12. No abstract available.


Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases: Highlights from basic research to therapy.

Huertas A, Guignabert C, Barberà JA, Bärtsch P, Bhattacharya J, Bhattacharya S, Bonsignore MR, Dewachter L, Dinh-Xuan AT, Dorfmüller P, Gladwin MT, Humbert M, Kotsimbos T, Vassilakopoulos T, Sanchez O, Savale L, Testa U, Wilkins MR.

Eur Respir J. 2018 Apr 4;51(4). pii: 1700745. doi: 10.1183/13993003.00745-2017. Print 2018 Apr. Review.


Use of autobilevel ventilation in patients with obstructive sleep apnea: An observational study.

Baiamonte P, Mazzuca E, Gruttad'Auria CI, Castrogiovanni A, Marino C, Lo Nardo D, Basile M, Algeri M, Battaglia S, Marrone O, Gagliardo A, Bonsignore MR.

J Sleep Res. 2018 Dec;27(6):e12680. doi: 10.1111/jsr.12680. Epub 2018 Mar 12.


Clinical physiology and sleep: insights from the European Respiratory Society Congress 2017.

Almendros I, Crespo A, Tura-Ceide O, Bonsignore MR.

J Thorac Dis. 2017 Nov;9(Suppl 16):S1532-S1536. doi: 10.21037/jtd.2017.11.44. Review. No abstract available.


Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment.

Bonsignore MR, Suarez Giron MC, Marrone O, Castrogiovanni A, Montserrat JM.

Eur Respir Rev. 2017 Oct 25;26(146). pii: 170069. doi: 10.1183/16000617.0069-2017. Print 2017 Dec 31. Review.


Oropharyngeal dysphagia: when swallowing disorders meet respiratory diseases.

Verin E, Clavé P, Bonsignore MR, Marie JP, Bertolus C, Similowski T, Laveneziana P.

Eur Respir J. 2017 Apr 12;49(4). pii: 1602530. doi: 10.1183/13993003.02530-2016. Print 2017 Apr. No abstract available.


Editorial commentary: Sleep disordered breathing and cardiovascular outcomes: Is it time to change our thinking?

Bonsignore MR.

Trends Cardiovasc Med. 2017 May;27(4):290-292. doi: 10.1016/j.tcm.2017.01.001. Epub 2017 Jan 6. No abstract available.


Cardiovascular Events in Moderately to Severely Obese Obstructive Sleep Apnea Patients on Positive Airway Pressure Therapy.

Marotta AM, Borel JC, Galerneau LM, Tamisier R, Bonsignore MR, Pépin JL.

Respiration. 2017;93(3):179-188. doi: 10.1159/000454988. Epub 2017 Jan 13.


Clinical Phenotypes and Comorbidity in European Sleep Apnoea Patients.

Saaresranta T, Hedner J, Bonsignore MR, Riha RL, McNicholas WT, Penzel T, Anttalainen U, Kvamme JA, Pretl M, Sliwinski P, Verbraecken J, Grote L; ESADA Study Group.

PLoS One. 2016 Oct 4;11(10):e0163439. doi: 10.1371/journal.pone.0163439. eCollection 2016.


Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment.

Petrone A, Mormile F, Bruni G, Quartieri M, Bonsignore MR, Marrone O.

Sleep Med. 2016 Jul;23:21-25. doi: 10.1016/j.sleep.2016.07.002. Epub 2016 Jul 25.


Mild Aerobic Exercise Training Hardly Affects the Diaphragm of mdx Mice.

Morici G, Frinchi M, Pitruzzella A, Di Liberto V, Barone R, Pace A, Di Felice V, Belluardo N, Cappello F, Mudò G, Bonsignore MR.

J Cell Physiol. 2017 Aug;232(8):2044-2052. doi: 10.1002/jcp.25573. Epub 2017 Mar 24.


Endurance training: is it bad for you?

Morici G, Gruttad'Auria CI, Baiamonte P, Mazzuca E, Castrogiovanni A, Bonsignore MR.

Breathe (Sheff). 2016 Jun;12(2):140-7. doi: 10.1183/20734735.007016. Review.


Mild obstructive sleep apnoea: clinical relevance and approaches to management.

McNicholas WT, Bonsignore MR, Lévy P, Ryan S.

Lancet Respir Med. 2016 Oct;4(10):826-834. doi: 10.1016/S2213-2600(16)30146-1. Epub 2016 May 27. Review.


Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells.

Pace E, Di Vincenzo S, Ferraro M, Bruno A, Dino P, Bonsignore MR, Battaglia S, Saibene F, Lanata L, Gjomarkaj M.

Exp Gerontol. 2016 Aug;81:119-28. doi: 10.1016/j.exger.2016.05.013. Epub 2016 May 26.


Chronic kidney disease in European patients with obstructive sleep apnea: the ESADA cohort study.

Marrone O, Battaglia S, Steiropoulos P, Basoglu OK, Kvamme JA, Ryan S, Pepin JL, Verbraecken J, Grote L, Hedner J, Bonsignore MR; ESADA study group.

J Sleep Res. 2016 Dec;25(6):739-745. doi: 10.1111/jsr.12426. Epub 2016 May 18.


The puzzle of metabolic effects of obstructive sleep apnoea in children.

Marrone O, Bonsignore MR.

Eur Respir J. 2016 Apr;47(4):1050-3. doi: 10.1183/13993003.00115-2016. No abstract available.


New rules on driver licensing for patients with obstructive sleep apnea: European Union Directive 2014/85/EU.

Bonsignore MR, Randerath W, Riha R, Smyth D, Gratziou C, Gonçalves M, McNicholas WT.

J Sleep Res. 2016 Feb;25(1):3-4. doi: 10.1111/jsr.12379. No abstract available.


Lack of Dystrophin Affects Bronchial Epithelium in mdx Mice.

Morici G, Rappa F, Cappello F, Pace E, Pace A, Mudò G, Crescimanno G, Belluardo N, Bonsignore MR.

J Cell Physiol. 2016 Oct;231(10):2218-23. doi: 10.1002/jcp.25339. Epub 2016 Mar 10.


Sleep disorders in menopause: results from an Italian Multicentric Study.

Fabbrini M, Aricà I, Tramonti F, Condurso R, Carnicelli L, De Rosa A, Di Perri C, Bonsignore MR, Zito A, Russo G, Pagliarulo MG, Guarnieri B, Cerroni G, Mennuni G, Della Marca G, Bonanni E, Silvestri R.

Arch Ital Biol. 2015 Jun-Sep;153(2-3):204-13. doi: 10.12871/0003982920152345.


Relaxin in Obstructive Sleep Apnea: Relationship with Blood Pressure and Inflammatory Mediators.

Bonanno A, Riccobono L, Bonsignore MR, Lo Bue A, Salvaggio A, Insalaco G, Marrone O.

Respiration. 2016;91(1):56-62. doi: 10.1159/000443182. Epub 2016 Jan 6.


New rules on driver licensing for patients with obstructive sleep apnoea: EU Directive 2014/85/EU.

Bonsignore MR, Randerath W, Riha R, Smyth D, Gratziou C, Goncalves M, McNicholas WT.

Eur Respir J. 2016 Jan;47(1):39-41. doi: 10.1183/13993003.01894-2015. No abstract available.


Obstructive Sleep Apnea Is Associated with Liver Damage and Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease.

Petta S, Marrone O, Torres D, Buttacavoli M, Cammà C, Di Marco V, Licata A, Lo Bue A, Parrinello G, Pinto A, Salvaggio A, Tuttolomondo A, Craxì A, Bonsignore MR.

PLoS One. 2015 Dec 16;10(12):e0142210. doi: 10.1371/journal.pone.0142210. eCollection 2015.


Liver Steatosis and Fibrosis in OSA patients After Long-term CPAP Treatment: A Preliminary Ultrasound Study.

Buttacavoli M, Gruttad'Auria CI, Olivo M, Virdone R, Castrogiovanni A, Mazzuca E, Marotta AM, Marrone O, Madonia S, Bonsignore MR.

Ultrasound Med Biol. 2016 Jan;42(1):104-9. doi: 10.1016/j.ultrasmedbio.2015.08.009. Epub 2015 Sep 15.


A Randomized Controlled Trial of Continuous Positive Airway Pressure on Glucose Tolerance in Obese Patients with Obstructive Sleep Apnea.

Salord N, Fortuna AM, Monasterio C, Gasa M, Pérez A, Bonsignore MR, Vilarrasa N, Montserrat JM, Mayos M.

Sleep. 2016 Jan 1;39(1):35-41. doi: 10.5665/sleep.5312.


Introducing a core curriculum for respiratory sleep practitioners.

Mitchell S, Simonds A, Andreas S, Bonsignore MR, Cooper B, Donic V, McNicholas WT, Morrell M, Palange P, Prest G, Riha R, Trang H, Randerath W, van der Grinten C, Verbraecken J, de Backer W.

Breathe (Sheff). 2015 Mar;11(1):50-6. doi: 10.1183/20734735.020414. Review.


Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience.

Bonsignore MR, Profita M, Gagliardo R, Riccobono L, Chiappara G, Pace E, Gjomarkaj M.

Eur Respir Rev. 2015 Mar;24(135):30-9. doi: 10.1183/09059180.10011114. Review.


Diabetes mellitus prevalence and control in sleep-disordered breathing: the European Sleep Apnea Cohort (ESADA) study.

Kent BD, Grote L, Ryan S, Pépin JL, Bonsignore MR, Tkacova R, Saaresranta T, Verbraecken J, Lévy P, Hedner J, McNicholas WT.

Chest. 2014 Oct;146(4):982-990. doi: 10.1378/chest.13-2403.


Sleep apnoea severity independently predicts glycaemic health in nondiabetic subjects: the ESADA study.

Kent BD, Grote L, Bonsignore MR, Saaresranta T, Verbraecken J, Lévy P, Sliwinski P, Tkacova R, Kvamme JA, Fietze I, Hedner J, McNicholas WT; European Sleep Apnoea Database collaborators.

Eur Respir J. 2014 Jul;44(1):130-9. doi: 10.1183/09031936.00162713. Epub 2014 Apr 2.


Hyperuricemia and non-dipping blood pressure.

Marrone O, Bonsignore MR.

Int J Nephrol Renovasc Dis. 2013 Dec 4;6:269-70. doi: 10.2147/IJNRD.S55750. eCollection 2013. No abstract available.


Gender-specific anthropometric markers of adiposity, metabolic syndrome and visceral adiposity index (VAI) in patients with obstructive sleep apnea.

Mazzuca E, Battaglia S, Marrone O, Marotta AM, Castrogiovanni A, Esquinas C, Barcelò A, Barbé F, Bonsignore MR.

J Sleep Res. 2014 Feb;23(1):13-21. doi: 10.1111/jsr.12088. Epub 2013 Oct 9.


Sleep apnoea and metabolic dysfunction.

Bonsignore MR, Borel AL, Machan E, Grunstein R.

Eur Respir Rev. 2013 Sep 1;22(129):353-64. doi: 10.1183/09059180.00003413. Review.


Plasma leptin and vascular endothelial growth factor (VEGF) in normal subjects at high altitude (5050 m).

Morici G, Bonanno A, Licciardi A, Valli G, Passino C, Bonardi D, Locorotondo N, Profita M, Palange P, Cogo A, Bonsignore MR.

Arch Physiol Biochem. 2013 Dec;119(5):219-24. doi: 10.3109/13813455.2013.814679. Epub 2013 Jul 17.


Recommendations for the management of patients with obstructive sleep apnoea and hypertension.

Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Lévy P, Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT; EU COST Action B26 members.

Eur Respir J. 2013 Mar;41(3):523-38. doi: 10.1183/09031936.00226711. Epub 2013 Feb 8.

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