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Items: 1 to 50 of 511

1.

Evaluation of in vitro activity of ceftazidime/avibactam and ceftolozane/tazobactam against MDR Pseudomonas aeruginosa isolates from Qatar.

Sid Ahmed MA, Abdel Hadi H, Hassan AAI, Abu Jarir S, Al-Maslamani MA, Eltai NO, Dousa KM, Hujer AM, Sultan AA, Soderquist B, Bonomo RA, Ibrahim EB, Jass J, Omrani AS.

J Antimicrob Chemother. 2019 Sep 3. pii: dkz379. doi: 10.1093/jac/dkz379. [Epub ahead of print]

PMID:
31504587
2.

Protein determinants of dissemination and host specificity of metallo-β-lactamases.

López C, Ayala JA, Bonomo RA, González LJ, Vila AJ.

Nat Commun. 2019 Aug 9;10(1):3617. doi: 10.1038/s41467-019-11615-w.

3.

Identification of Potential Virulence Factors in the Model Strain Acinetobacter baumannii A118.

Ramirez MS, Penwell WF, Traglia GM, Zimbler DL, Gaddy JA, Nikolaidis N, Arivett BA, Adams MD, Bonomo RA, Actis LA, Tolmasky ME.

Front Microbiol. 2019 Jul 23;10:1599. doi: 10.3389/fmicb.2019.01599. eCollection 2019.

4.

Therapeutic efficacy of LN-1-255 in combination with imipenem in severe infection caused by carbapenem-resistant Acinetobacter baumannii.

Vázquez-Ucha JC, Martínez-Guitián M, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, González-Bello C, Poza M, Beceiro A.

Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.01092-19. doi: 10.1128/AAC.01092-19. [Epub ahead of print]

PMID:
31383666
5.

Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion.

Rodman N, Martinez J, Fung S, Nakanouchi J, Myers AL, Harris CM, Dang E, Fernandez JS, Liu C, Mendoza AM, Jimenez V, Nikolaidis N, Brennan CA, Bonomo RA, Sieira R, Ramirez MS.

Front Microbiol. 2019 Jul 17;10:1581. doi: 10.3389/fmicb.2019.01581. eCollection 2019.

6.

External validation of the INCREMENT-CPE mortality score in a carbapenem-resistant Klebsiella pneumoniae bacteraemia cohort: the prognostic significance of colistin resistance.

Machuca I, Gutiérrez-Gutiérrez B, Rivera-Espinar F, Cano A, Gracia-Ahufinger I, Guzman-Puche J, Marfil-Pérez E, Pérez-Nadales E, Castón JJ, Bonomo RA, Carmeli Y, Paterson D, Pascual Á, Martínez-Martínez L, Rodríguez-Baño J, Torre-Cisneros J; REIPI/ESGBIS/INCREMENT Group.

Int J Antimicrob Agents. 2019 Aug 1. pii: S0924-8579(19)30206-7. doi: 10.1016/j.ijantimicag.2019.07.017. [Epub ahead of print]

PMID:
31377343
7.

Multidrug-Resistant Gram-Negative Pathogens: The Urgent Need for 'Old' Polymyxins.

Paterson DL, Bonomo RA.

Adv Exp Med Biol. 2019;1145:9-13. doi: 10.1007/978-3-030-16373-0_2. Review.

PMID:
31364068
8.

Identification of four patients with colistin-resistant Escherichia coli containing the mobile colistin resistance mcr-1 gene from a single health system in Michigan.

Henig O, Rojas LJ, Bachman MA, Rudin SD, Brennan BM, Soehnlen MK, Jones KL, Mills JP, Dombecki CR, Valyko AM, Marshall SH, Bonomo RA, Kaye KS, Washer L.

Infect Control Hosp Epidemiol. 2019 Sep;40(9):1059-1062. doi: 10.1017/ice.2019.177. Epub 2019 Jul 15.

PMID:
31303191
9.

Corrigendum to: 1757. Using the Desirability of Outcome Ranking for Management of Antimicrobial Therapy (DOOR-MAT) to Assess Antibiotic Therapy Guided by Rapid Molecular Diagnostics (RMD) in Bloodstream Infection (BSI) Caused by Escherichia coli and Klebsiella pneumonia.

Wilson B, Viau R, Perez F, Jiang H, Fowler VG Jr, Chambers HF, Kreiswirth BN, Bonomo RA, Evans SR; ARLG.

Open Forum Infect Dis. 2019 Jul 3;6(7):ofz267. doi: 10.1093/ofid/ofz267. eCollection 2019 Jul.

10.

Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump.

Su CC, Morgan CE, Kambakam S, Rajavel M, Scott H, Huang W, Emerson CC, Taylor DJ, Stewart PL, Bonomo RA, Yu EW.

MBio. 2019 Jul 2;10(4). pii: e01295-19. doi: 10.1128/mBio.01295-19.

11.

Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States.

Mojica MF, Rutter JD, Taracila M, Abriata LA, Fouts DE, Papp-Wallace KM, Walsh TJ, LiPuma JJ, Vila AJ, Bonomo RA.

MBio. 2019 Jul 2;10(4). pii: e00405-19. doi: 10.1128/mBio.00405-19.

12.

Structural Insights into the Inhibition of the Extended-Spectrum β-Lactamase PER-2 by Avibactam.

Ruggiero M, Papp-Wallace KM, Brunetti F, Barnes MD, Bonomo RA, Gutkind G, Klinke S, Power P.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00487-19. doi: 10.1128/AAC.00487-19. Print 2019 Sep.

PMID:
31235626
13.

The Pitt Bacteremia Score Predicts Mortality in Non-Bacteremic Infections.

Henderson H, Luterbach CL, Cober E, Richter SS, Salata RA, Kalayjian RC, Watkins RR, Doi Y, Kaye KS, Evans S, Fowler VG, Bonomo RA, Harris A, Napravnik S, van Duin D.

Clin Infect Dis. 2019 Jun 19. pii: ciz528. doi: 10.1093/cid/ciz528. [Epub ahead of print]

PMID:
31219148
14.

Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC.

Barnes MD, Taracila MA, Good CE, Bajaksouzian S, Rojas LJ, van Duin D, Kreiswirth BN, Jacobs MR, Haldimann A, Papp-Wallace KM, Bonomo RA.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00432-19. doi: 10.1128/AAC.00432-19. Print 2019 Aug.

PMID:
31182530
15.

Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria.

Luna BM, Ershova K, Yan J, Ulhaq A, Nielsen TB, Hsieh S, Pantapalangkoor P, Vanscoy B, Ambrose P, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar EP, Spellberg B.

J Antimicrob Chemother. 2019 Sep 1;74(9):2631-2639. doi: 10.1093/jac/dkz225.

PMID:
31170282
16.

Ceftazidime-Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa.

Papp-Wallace KM, Zeiser ET, Becka SA, Park S, Wilson BM, Winkler ML, D'Souza R, Singh I, Sutton G, Fouts DE, Chen L, Kreiswirth BN, Ellis-Grosse EJ, Drusano GL, Perlin DS, Bonomo RA.

J Infect Dis. 2019 May 17. pii: jiz149. doi: 10.1093/infdis/jiz149. [Epub ahead of print]

PMID:
31099835
17.

Cardiac Devices Enveloped with an Ounce of Prevention.

Perez F, Bonomo RA.

N Engl J Med. 2019 May 16;380(20):1965-1966. doi: 10.1056/NEJMe1905678. No abstract available.

PMID:
31091379
18.

Patient-to-Patient Transmission of Acinetobacter baumannii Gastrointestinal Colonization in the Intensive Care Unit.

Harris AD, Johnson JK, Pineles L, O'Hara LM, Bonomo RA, Thom KA.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00392-19. doi: 10.1128/AAC.00392-19. Print 2019 Aug.

PMID:
31085518
19.

Carbapenem-resistant Enterobacteriaceae: global action required.

Perez F, Bonomo RA.

Lancet Infect Dis. 2019 Jun;19(6):561-562. doi: 10.1016/S1473-3099(19)30210-5. Epub 2019 Apr 29. No abstract available.

PMID:
31047851
20.

Antibiotic Resistance in Enterobacteriaceae from Surface Waters in Urban Brazil Highlights the Risks of Poor Sanitation.

Bartley PS, Domitrovic TN, Moretto VT, Santos CS, Ponce-Terashima R, Reis MG, Barbosa LM, Blanton RE, Bonomo RA, Perez F.

Am J Trop Med Hyg. 2019 Jun;100(6):1369-1377. doi: 10.4269/ajtmh.18-0726.

PMID:
30994094
21.

Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.

Jiao Y, Moya B, Chen MJ, Zavascki AP, Tsai H, Tao X, Sutaria DS, Louie A, Boyce JD, Deveson Lucas D, Kim TH, Tsuji BT, Bonomo RA, Drusano GL, Bulitta JB.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00425-19. doi: 10.1128/AAC.00425-19. Print 2019 Jul.

PMID:
30988147
22.

Polymyxins: To Combine or Not to Combine?

Perez F, El Chakhtoura NG, Yasmin M, Bonomo RA.

Antibiotics (Basel). 2019 Apr 10;8(2). pii: E38. doi: 10.3390/antibiotics8020038. Review.

23.

Reply to Humphrey and Spafford.

Bonomo RA, Evans SR.

Clin Infect Dis. 2019 Apr 6. pii: ciz228. doi: 10.1093/cid/ciz228. [Epub ahead of print] No abstract available.

PMID:
30953056
24.

Rapid Replacement of Acinetobacter baumannii Strains Accompanied by Changes in Lipooligosaccharide Loci and Resistance Gene Repertoire.

Adams MD, Wright MS, Karichu JK, Venepally P, Fouts DE, Chan AP, Richter SS, Jacobs MR, Bonomo RA.

MBio. 2019 Mar 26;10(2). pii: e00356-19. doi: 10.1128/mBio.00356-19.

25.

Epidemiology and genotypic characterisation of dissemination patterns of uropathogenic Escherichia coli in a community.

Matsukawa M, Igarashi M, Watanabe H, Qin L, Ohnishi M, Terajima J, Iyoda S, Morita-Ishihara T, Tateda K, Ishii Y, Saga T, Aoki K, Bonomo RA.

Epidemiol Infect. 2019 Jan;147:e148. doi: 10.1017/S0950268819000426.

26.

Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent.

Barnes MD, Kumar V, Bethel CR, Moussa SH, O'Donnell J, Rutter JD, Good CE, Hujer KM, Hujer AM, Marshall SH, Kreiswirth BN, Richter SS, Rather PN, Jacobs MR, Papp-Wallace KM, van den Akker F, Bonomo RA.

MBio. 2019 Mar 12;10(2). pii: e00159-19. doi: 10.1128/mBio.00159-19.

27.

Beyond Piperacillin-Tazobactam: Cefepime and AAI101 as a Potent β-Lactam-β-Lactamase Inhibitor Combination.

Papp-Wallace KM, Bethel CR, Caillon J, Barnes MD, Potel G, Bajaksouzian S, Rutter JD, Reghal A, Shapiro S, Taracila MA, Jacobs MR, Bonomo RA, Jacqueline C.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00105-19. doi: 10.1128/AAC.00105-19. Print 2019 May.

PMID:
30858223
28.

A Primer on AmpC Beta-Lactamases: Necessary Knowledge for an Increasingly Multidrug-Resistant World.

Tamma PD, Doi Y, Bonomo RA, Johnson JK, Simner PJ; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2019 Mar 6. pii: ciz173. doi: 10.1093/cid/ciz173. [Epub ahead of print]

PMID:
30838380
29.

Whole Genome Sequence Analysis of Burkholderia contaminans FFH2055 Strain Reveals the Presence of Putative β-Lactamases.

Degrossi JJ, Merino C, Isasmendi AM, Ibarra LM, Collins C, Bo NE, Papalia M, Fernandez JS, Hernandez CM, Papp-Wallace KM, Bonomo RA, Vazquez MS, Power P, Ramirez MS.

Curr Microbiol. 2019 Apr;76(4):485-494. doi: 10.1007/s00284-019-01653-4. Epub 2019 Feb 19.

PMID:
30783798
30.

Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect.

Ambrose PG, VanScoy BD, Luna BM, Yan J, Ulhaq A, Nielsen TB, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar E, Spellberg B.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00112-19. doi: 10.1128/AAC.00112-19. Print 2019 May.

PMID:
30782989
31.

Shedding of methicillin-resistant Staphylococcus aureus by colonized patients during procedures and patient care activities.

Alhmidi H, Cadnum JL, Koganti S, Jencson AL, Rutter JD, Bonomo RA, Wilson BM, Mayer J, Samore MH, Donskey CJ.

Infect Control Hosp Epidemiol. 2019 Mar;40(3):328-332. doi: 10.1017/ice.2018.342. Epub 2019 Feb 19.

PMID:
30777587
32.

The Clinical and Molecular Epidemiology of CTX-M-9 Group Producing Enterobacteriaceae Infections in Children.

Logan LK, Medernach RL, Domitrovic TN, Rispens JR, Hujer AM, Qureshi NK, Marshall SH, Nguyen DC, Rudin SD, Zheng X, Konda S, Weinstein RA, Bonomo RA.

Infect Dis Ther. 2019 Jun;8(2):243-254. doi: 10.1007/s40121-019-0237-2. Epub 2019 Feb 16.

33.

Dual β-Lactam Combinations Highly Active against Mycobacterium abscessus Complex In Vitro.

Pandey R, Chen L, Manca C, Jenkins S, Glaser L, Vinnard C, Stone G, Lee J, Mathema B, Nuermberger EL, Bonomo RA, Kreiswirth BN.

MBio. 2019 Feb 12;10(1). pii: e02895-18. doi: 10.1128/mBio.02895-18.

34.

Antibiotic collateral sensitivity is contingent on the repeatability of evolution.

Nichol D, Rutter J, Bryant C, Hujer AM, Lek S, Adams MD, Jeavons P, Anderson ARA, Bonomo RA, Scott JG.

Nat Commun. 2019 Jan 18;10(1):334. doi: 10.1038/s41467-018-08098-6.

35.

The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae.

Luterbach CL, Boshe A, Henderson HI, Cober E, Richter SS, Salata RA, Kalayjian RC, Watkins RR, Hujer AM, Hujer KM, Rudin SD, Domitrovic TN, Doi Y, Kaye KS, Evans S, Fowler VG Jr, Bonomo RA, van Duin D.

Open Forum Infect Dis. 2018 Dec 14;6(1):ofy351. doi: 10.1093/ofid/ofy351. eCollection 2019 Jan.

36.

Interspecies DNA acquisition by a naturally competent Acinetobacter baumannii strain.

Traglia GM, Place K, Dotto C, Fernandez JS, Montaña S, Bahiense CDS, Soler-Bistue A, Iriarte A, Perez F, Tolmasky ME, Bonomo RA, Melano RG, Ramírez MS.

Int J Antimicrob Agents. 2019 Apr;53(4):483-490. doi: 10.1016/j.ijantimicag.2018.12.013. Epub 2019 Jan 3.

PMID:
30611868
37.

A Comparison of Cefazolin Versus Ceftriaxone for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia in a Tertiary Care VA Medical Center.

Carr DR, Stiefel U, Bonomo RA, Burant CJ, Sims SV.

Open Forum Infect Dis. 2018 May 18;5(5):ofy089. doi: 10.1093/ofid/ofy089. eCollection 2018 May.

38.

1H, 13C, and 15N backbone resonance assignments for KPC-2, a class A serine-β-lactamase.

VanPelt J, Shurina BA, Ramelot TA, Bonomo RA, Page RC.

Biomol NMR Assign. 2019 Apr;13(1):139-142. doi: 10.1007/s12104-018-9866-8. Epub 2018 Dec 14.

PMID:
30552637
39.

Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa.

Barnes MD, Taracila MA, Rutter JD, Bethel CR, Galdadas I, Hujer AM, Caselli E, Prati F, Dekker JP, Papp-Wallace KM, Haider S, Bonomo RA.

MBio. 2018 Dec 11;9(6). pii: e02085-18. doi: 10.1128/mBio.02085-18.

40.

Human fluids alter DNA-acquisition in Acinetobacter baumannii.

Martinez J, Liu C, Rodman N, Fernandez JS, Barberis C, Sieira R, Perez F, Bonomo RA, Ramirez MS.

Diagn Microbiol Infect Dis. 2019 Mar;93(3):183-187. doi: 10.1016/j.diagmicrobio.2018.10.010. Epub 2018 Oct 23.

PMID:
30420211
41.

Sequential, Multiple-Assignment, Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS).

Evans SR, Follmann D, Liu Y, Holland T, Doernberg SB, Rouphael N, Hamasaki T, Jiang Y, Lok JJ, Tran TTT, Harris AD, Fowler VG, Boucher H, Kreiswirth BN, Bonomo RA, Van Duin D, Paterson DL, Chambers H.

Clin Infect Dis. 2019 May 17;68(11):1961-1967. doi: 10.1093/cid/ciy912.

PMID:
30351426
42.

The Reaction Mechanism of Metallo-β-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop.

Palacios AR, Mojica MF, Giannini E, Taracila MA, Bethel CR, Alzari PM, Otero LH, Klinke S, Llarrull LI, Bonomo RA, Vila AJ.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01754-18. doi: 10.1128/AAC.01754-18. Print 2019 Jan.

43.

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases.

Jacobs MR, Abdelhamed AM, Good CE, Rhoads DD, Hujer KM, Hujer AM, Domitrovic TN, Rudin SD, Richter SS, van Duin D, Kreiswirth BN, Greco C, Fouts DE, Bonomo RA.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01801-18. doi: 10.1128/AAC.01801-18. Print 2019 Jan.

44.

New Treatment Options against Carbapenem-Resistant Acinetobacter baumannii Infections.

Isler B, Doi Y, Bonomo RA, Paterson DL.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01110-18. doi: 10.1128/AAC.01110-18. Print 2019 Jan. Review.

45.

Epidemiology of Carbapenem-Resistant Enterobacteriaceae at a Long-term Acute Care Hospital.

Chopra T, Rivard C, Awali RA, Krishna A, Bonomo RA, Perez F, Kaye KS.

Open Forum Infect Dis. 2018 Oct 3;5(10):ofy224. doi: 10.1093/ofid/ofy224. eCollection 2018 Oct.

46.

Human serum albumin alters specific genes that can play a role in survival and persistence in Acinetobacter baumannii.

Quinn B, Rodman N, Jara E, Fernandez JS, Martinez J, Traglia GM, Montaña S, Cantera V, Place K, Bonomo RA, Iriarte A, Ramírez MS.

Sci Rep. 2018 Oct 3;8(1):14741. doi: 10.1038/s41598-018-33072-z.

47.

Community Origins and Regional Differences Highlight Risk of Plasmid-mediated Fluoroquinolone Resistant Enterobacteriaceae Infections in Children.

Logan LK, Medernach RL, Rispens JR, Marshall SH, Hujer AM, Domitrovic TN, Rudin SD, Zheng X, Qureshi NK, Konda S, Hayden MK, Weinstein RA, Bonomo RA.

Pediatr Infect Dis J. 2019 Jun;38(6):595-599. doi: 10.1097/INF.0000000000002205.

PMID:
30281548
48.

Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV.

Evans SR, Tran TTT, Hujer AM, Hill CB, Hujer KM, Mediavilla JR, Manca C, Domitrovic TN, Perez F, Farmer M, Pitzer KM, Wilson BM, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Fowler VG, Chambers HF, Bonomo RA; Antibacterial Resistance Leadership Group (ARLG).

Clin Infect Dis. 2019 May 17;68(11):1823-1830. doi: 10.1093/cid/ciy801.

PMID:
30239599
49.

Acinetobacter nosocomialis: Defining the Role of Efflux Pumps in Resistance to Antimicrobial Therapy, Surface Motility, and Biofilm Formation.

Knight DB, Rudin SD, Bonomo RA, Rather PN.

Front Microbiol. 2018 Aug 21;9:1902. doi: 10.3389/fmicb.2018.01902. eCollection 2018.

50.

A Multi-Centered Case-Case-Control Study of Factors Associated With Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae Infections in Children and Young Adults.

Logan LK, Nguyen DC, Scaggs Huang FA, Qureshi NK, Charnot-Katsikas A, Bartlett AH, Zheng X, Hujer AM, Domitrovic TN, Marshall SH, Bonomo RA, Weinstein RA.

Pediatr Infect Dis J. 2019 May;38(5):490-495. doi: 10.1097/INF.0000000000002176.

PMID:
30169484

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