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Items: 1 to 50 of 529

1.

Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae.

Kim TH, Tao X, Moya B, Jiao Y, Basso KB, Zhou J, Lang Y, Sutaria DS, Zavascki AP, Barth AL, Reeve SM, Schweizer HP, Deveson Lucas D, Boyce JD, Bonomo RA, Lee RE, Shin BS, Louie A, Drusano GL, Bulitta JB.

mBio. 2020 Feb 11;11(1). pii: e03189-19. doi: 10.1128/mBio.03189-19.

2.

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.

Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE, Bonomo RA, Yu EW.

mBio. 2020 Jan 21;11(1). pii: e03117-19. doi: 10.1128/mBio.03117-19.

3.

A multicenter randomized placebo controlled trial of rifampin to reduce pedal amputations for osteomyelitis in veterans with diabetes (VA INTREPID).

Bessesen MT, Doros G, Henrie AM, Harrington KM, Hermos JA, Bonomo RA, Ferguson RE, Huang GD, Brown ST.

BMC Infect Dis. 2020 Jan 8;20(1):23. doi: 10.1186/s12879-019-4751-3.

4.

Reply to Vena, et al.

Pogue JM, Kaye KS, Bonomo RA, Perez F.

Clin Infect Dis. 2020 Jan 6. pii: ciaa004. doi: 10.1093/cid/ciaa004. [Epub ahead of print] No abstract available.

PMID:
31904808
5.

Carbapenem susceptible Klebsiella pneumoniae and Escherichia coli carrying a truncated KPC carbapenemase: a challenge for rapid molecular diagnostics.

Salimnia H, Veltman J, Chandrasekar PH, Pogue J, Mynatt R, Salimnia T, Marshall SH, Hujer AM, Bonomo RA.

J Clin Microbiol. 2019 Dec 18. pii: JCM.01627-19. doi: 10.1128/JCM.01627-19. [Epub ahead of print]

PMID:
31852760
6.

Monitoring Ceftazidime-Avibactam (CAZ-AVI) and Aztreonam (ATM) Concentrations in the Treatment of a Bloodstream Infection Caused by a Multidrug-Resistant Enterobacter sp. Carrying both KPC-4 and NDM-1 Carbapenemases.

Yasmin M, Fouts DE, Jacobs MR, Haydar H, Marshall SH, White R, D'Souza R, Lodise TP, Rhoads DD, Hujer AM, Rojas LJ, Hoyen C, Perez F, Edwards A, Bonomo RA.

Clin Infect Dis. 2019 Dec 5. pii: ciz1155. doi: 10.1093/cid/ciz1155. [Epub ahead of print]

PMID:
31802119
7.

Association of Lymphopenia With Risk of Mortality Among Adults in the US General Population.

Zidar DA, Al-Kindi SG, Liu Y, Krieger NI, Perzynski AT, Osnard M, Nmai C, Anthony DD, Lederman MM, Freeman ML, Bonomo RA, Simon DI, Dalton JE.

JAMA Netw Open. 2019 Dec 2;2(12):e1916526. doi: 10.1001/jamanetworkopen.2019.16526.

8.

Adjunctive Rifampin Therapy For Diabetic Foot Osteomyelitis in the Veterans Health Administration.

Wilson BM, Bessesen MT, Doros G, Brown ST, Saade E, Hermos J, Perez F, Skalweit M, Spellberg B, Bonomo RA.

JAMA Netw Open. 2019 Nov 1;2(11):e1916003. doi: 10.1001/jamanetworkopen.2019.16003.

9.

Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress.

Martinez J, Fernandez JS, Liu C, Hoard A, Mendoza A, Nakanouchi J, Rodman N, Courville R, Tuttobene MR, Lopez C, Gonzalez LJ, Shahrestani P, Papp-Wallace KM, Vila AJ, Tolmasky ME, Bonomo RA, Sieira R, Ramirez MS.

Sci Rep. 2019 Nov 21;9(1):17251. doi: 10.1038/s41598-019-53847-2.

10.

A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.

Cheng Z, Shurina BA, Bethel CR, Thomas PW, Marshall SH, Thomas CA, Yang K, Kimble RL, Montgomery JS, Orischak MG, Miller CM, Tennenbaum JL, Nix JC, Tierney DL, Fast W, Bonomo RA, Page RC, Crowder MW.

mBio. 2019 Nov 19;10(6). pii: e02412-19. doi: 10.1128/mBio.02412-19.

11.

Precision Medicine and Mysteries in Clinical Microbiology: Rationalizing Epidemiology, Genotype, and Phenotype To Guide Therapeutics.

Perez F, Bonomo RA.

Antimicrob Agents Chemother. 2020 Jan 27;64(2). pii: e02264-19. doi: 10.1128/AAC.02264-19. Print 2020 Jan 27.

PMID:
31740555
12.

Acinetobacter infections.

Wilson BM, Perez F, Pan Q, Jiang Y, Evans S, Bonomo RA.

Clin Infect Dis. 2019 Nov 17. pii: ciz1099. doi: 10.1093/cid/ciz1099. [Epub ahead of print] No abstract available.

PMID:
31734703
13.

Cefiderocol: A Novel Siderophore Cephalosporin Defeating Carbapenem-resistant Pathogens.

Bonomo RA.

Clin Infect Dis. 2019 Nov 13;69(Supplement_7):S519-S520. doi: 10.1093/cid/ciz823.

14.

In vitro selection of aztreonam/avibactam resistance in dual-carbapenemase-producing Klebsiella pneumoniae.

Niu S, Wei J, Zou C, Chavda KD, Lv J, Zhang H, Du H, Tang YW, Pitout JDD, Bonomo RA, Kreiswirth BN, Chen L.

J Antimicrob Chemother. 2020 Mar 1;75(3):559-565. doi: 10.1093/jac/dkz468.

PMID:
31722380
15.

A standard numbering scheme for class C β-lactamases.

Mack AR, Barnes MD, Taracila MA, Hujer AM, Hujer KM, Cabot G, Feldgarden M, Haft DH, Klimke W, van den Akker F, Vila AJ, Smania A, Haider S, Papp-Wallace KM, Bradford PA, Rossolini GM, Docquier JD, Frère JM, Galleni M, Hanson ND, Oliver A, Plésiat P, Poirel L, Nordmann P, Palzkill TG, Jacoby GA, Bush K, Bonomo RA.

Antimicrob Agents Chemother. 2019 Nov 11. pii: AAC.01841-19. doi: 10.1128/AAC.01841-19. [Epub ahead of print]

PMID:
31712217
16.

Longitudinal Colonization With Streptococcus pneumoniae During the First Year of Life in a Healthy Newborn Cohort.

Meropol SB, Jacobs MR, Stange KC, Bajaksouzian S, Bonomo RA.

J Pediatric Infect Dis Soc. 2019 Oct 31. pii: piz068. doi: 10.1093/jpids/piz068. [Epub ahead of print]

PMID:
31670814
17.

Ceftolozane/Tazobactam vs Polymyxin or Aminoglycoside-based Regimens for the Treatment of Drug-resistant Pseudomonas Aeruginosa.

Pogue JM, Kaye KS, Veve MP, Patel TS, Gerlach AT, Davis SL, Puzniak LA, File TM, Olson S, Dhar S, Bonomo RA, Perez F.

Clin Infect Dis. 2019 Sep 23. pii: ciz816. doi: 10.1093/cid/ciz816. [Epub ahead of print]

PMID:
31545346
18.

Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection.

Khil PP, Dulanto Chiang A, Ho J, Youn JH, Lemon JK, Gea-Banacloche J, Frank KM, Parta M, Bonomo RA, Dekker JP.

mBio. 2019 Sep 17;10(5). pii: e01822-19. doi: 10.1128/mBio.01822-19.

19.

Evaluation of in vitro activity of ceftazidime/avibactam and ceftolozane/tazobactam against MDR Pseudomonas aeruginosa isolates from Qatar.

Sid Ahmed MA, Abdel Hadi H, Hassan AAI, Abu Jarir S, Al-Maslamani MA, Eltai NO, Dousa KM, Hujer AM, Sultan AA, Soderquist B, Bonomo RA, Ibrahim EB, Jass J, Omrani AS.

J Antimicrob Chemother. 2019 Dec 1;74(12):3497-3504. doi: 10.1093/jac/dkz379.

PMID:
31504587
20.

Protein determinants of dissemination and host specificity of metallo-β-lactamases.

López C, Ayala JA, Bonomo RA, González LJ, Vila AJ.

Nat Commun. 2019 Aug 9;10(1):3617. doi: 10.1038/s41467-019-11615-w.

21.

Identification of Potential Virulence Factors in the Model Strain Acinetobacter baumannii A118.

Ramirez MS, Penwell WF, Traglia GM, Zimbler DL, Gaddy JA, Nikolaidis N, Arivett BA, Adams MD, Bonomo RA, Actis LA, Tolmasky ME.

Front Microbiol. 2019 Jul 23;10:1599. doi: 10.3389/fmicb.2019.01599. eCollection 2019.

22.

Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.

Vázquez-Ucha JC, Martínez-Guitián M, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, González-Bello C, Poza M, Beceiro A.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e01092-19. doi: 10.1128/AAC.01092-19. Print 2019 Oct.

PMID:
31383666
23.

Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion.

Rodman N, Martinez J, Fung S, Nakanouchi J, Myers AL, Harris CM, Dang E, Fernandez JS, Liu C, Mendoza AM, Jimenez V, Nikolaidis N, Brennan CA, Bonomo RA, Sieira R, Ramirez MS.

Front Microbiol. 2019 Jul 17;10:1581. doi: 10.3389/fmicb.2019.01581. eCollection 2019.

24.

External validation of the INCREMENT-CPE mortality score in a carbapenem-resistant Klebsiella pneumoniae bacteraemia cohort: the prognostic significance of colistin resistance.

Machuca I, Gutiérrez-Gutiérrez B, Rivera-Espinar F, Cano A, Gracia-Ahufinger I, Guzman-Puche J, Marfil-Pérez E, Pérez-Nadales E, Castón JJ, Bonomo RA, Carmeli Y, Paterson D, Pascual Á, Martínez-Martínez L, Rodríguez-Baño J, Torre-Cisneros J; REIPI/ESGBIS/INCREMENT Group.

Int J Antimicrob Agents. 2019 Oct;54(4):442-448. doi: 10.1016/j.ijantimicag.2019.07.017. Epub 2019 Aug 1.

PMID:
31377343
25.

Multidrug-Resistant Gram-Negative Pathogens: The Urgent Need for 'Old' Polymyxins.

Paterson DL, Bonomo RA.

Adv Exp Med Biol. 2019;1145:9-13. doi: 10.1007/978-3-030-16373-0_2. Review.

PMID:
31364068
26.

Identification of four patients with colistin-resistant Escherichia coli containing the mobile colistin resistance mcr-1 gene from a single health system in Michigan.

Henig O, Rojas LJ, Bachman MA, Rudin SD, Brennan BM, Soehnlen MK, Jones KL, Mills JP, Dombecki CR, Valyko AM, Marshall SH, Bonomo RA, Kaye KS, Washer L.

Infect Control Hosp Epidemiol. 2019 Sep;40(9):1059-1062. doi: 10.1017/ice.2019.177. Epub 2019 Jul 15.

PMID:
31303191
27.

Corrigendum to: 1757. Using the Desirability of Outcome Ranking for Management of Antimicrobial Therapy (DOOR-MAT) to Assess Antibiotic Therapy Guided by Rapid Molecular Diagnostics (RMD) in Bloodstream Infection (BSI) Caused by Escherichia coli and Klebsiella pneumonia.

Wilson B, Viau R, Perez F, Jiang H, Fowler VG Jr, Chambers HF, Kreiswirth BN, Bonomo RA, Evans SR; ARLG.

Open Forum Infect Dis. 2019 Jul 3;6(7):ofz267. doi: 10.1093/ofid/ofz267. eCollection 2019 Jul.

28.

Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump.

Su CC, Morgan CE, Kambakam S, Rajavel M, Scott H, Huang W, Emerson CC, Taylor DJ, Stewart PL, Bonomo RA, Yu EW.

mBio. 2019 Jul 2;10(4). pii: e01295-19. doi: 10.1128/mBio.01295-19.

29.

Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States.

Mojica MF, Rutter JD, Taracila M, Abriata LA, Fouts DE, Papp-Wallace KM, Walsh TJ, LiPuma JJ, Vila AJ, Bonomo RA.

mBio. 2019 Jul 2;10(4). pii: e00405-19. doi: 10.1128/mBio.00405-19.

30.

Structural Insights into the Inhibition of the Extended-Spectrum β-Lactamase PER-2 by Avibactam.

Ruggiero M, Papp-Wallace KM, Brunetti F, Barnes MD, Bonomo RA, Gutkind G, Klinke S, Power P.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00487-19. doi: 10.1128/AAC.00487-19. Print 2019 Sep.

PMID:
31235626
31.

The Pitt Bacteremia Score Predicts Mortality in Non-Bacteremic Infections.

Henderson H, Luterbach CL, Cober E, Richter SS, Salata RA, Kalayjian RC, Watkins RR, Doi Y, Kaye KS, Evans S, Fowler VG, Bonomo RA, Harris A, Napravnik S, van Duin D.

Clin Infect Dis. 2019 Jun 19. pii: ciz528. doi: 10.1093/cid/ciz528. [Epub ahead of print]

PMID:
31219148
32.

Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC.

Barnes MD, Taracila MA, Good CE, Bajaksouzian S, Rojas LJ, van Duin D, Kreiswirth BN, Jacobs MR, Haldimann A, Papp-Wallace KM, Bonomo RA.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00432-19. doi: 10.1128/AAC.00432-19. Print 2019 Aug.

33.

Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria.

Luna BM, Ershova K, Yan J, Ulhaq A, Nielsen TB, Hsieh S, Pantapalangkoor P, Vanscoy B, Ambrose P, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar EP, Spellberg B.

J Antimicrob Chemother. 2019 Sep 1;74(9):2631-2639. doi: 10.1093/jac/dkz225.

34.

Ceftazidime-Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa.

Papp-Wallace KM, Zeiser ET, Becka SA, Park S, Wilson BM, Winkler ML, D'Souza R, Singh I, Sutton G, Fouts DE, Chen L, Kreiswirth BN, Ellis-Grosse EJ, Drusano GL, Perlin DS, Bonomo RA.

J Infect Dis. 2019 Jul 19;220(4):666-676. doi: 10.1093/infdis/jiz149.

PMID:
31099835
35.

Cardiac Devices Enveloped with an Ounce of Prevention.

Perez F, Bonomo RA.

N Engl J Med. 2019 May 16;380(20):1965-1966. doi: 10.1056/NEJMe1905678. No abstract available.

PMID:
31091379
36.

Patient-to-Patient Transmission of Acinetobacter baumannii Gastrointestinal Colonization in the Intensive Care Unit.

Harris AD, Johnson JK, Pineles L, O'Hara LM, Bonomo RA, Thom KA.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00392-19. doi: 10.1128/AAC.00392-19. Print 2019 Aug.

37.

Carbapenem-resistant Enterobacteriaceae: global action required.

Perez F, Bonomo RA.

Lancet Infect Dis. 2019 Jun;19(6):561-562. doi: 10.1016/S1473-3099(19)30210-5. Epub 2019 Apr 29. No abstract available.

PMID:
31047851
38.

Antibiotic Resistance in Enterobacteriaceae from Surface Waters in Urban Brazil Highlights the Risks of Poor Sanitation.

Bartley PS, Domitrovic TN, Moretto VT, Santos CS, Ponce-Terashima R, Reis MG, Barbosa LM, Blanton RE, Bonomo RA, Perez F.

Am J Trop Med Hyg. 2019 Jun;100(6):1369-1377. doi: 10.4269/ajtmh.18-0726.

PMID:
30994094
39.

Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.

Jiao Y, Moya B, Chen MJ, Zavascki AP, Tsai H, Tao X, Sutaria DS, Louie A, Boyce JD, Deveson Lucas D, Kim TH, Tsuji BT, Bonomo RA, Drusano GL, Bulitta JB.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00425-19. doi: 10.1128/AAC.00425-19. Print 2019 Jul.

40.

Polymyxins: To Combine or Not to Combine?

Perez F, El Chakhtoura NG, Yasmin M, Bonomo RA.

Antibiotics (Basel). 2019 Apr 10;8(2). pii: E38. doi: 10.3390/antibiotics8020038. Review.

41.

Reply to Humphrey and Spafford.

Bonomo RA, Evans SR.

Clin Infect Dis. 2019 Oct 30;69(10):1831-1832. doi: 10.1093/cid/ciz228. No abstract available.

PMID:
30953056
42.

Rapid Replacement of Acinetobacter baumannii Strains Accompanied by Changes in Lipooligosaccharide Loci and Resistance Gene Repertoire.

Adams MD, Wright MS, Karichu JK, Venepally P, Fouts DE, Chan AP, Richter SS, Jacobs MR, Bonomo RA.

mBio. 2019 Mar 26;10(2). pii: e00356-19. doi: 10.1128/mBio.00356-19.

43.

Epidemiology and genotypic characterisation of dissemination patterns of uropathogenic Escherichia coli in a community.

Matsukawa M, Igarashi M, Watanabe H, Qin L, Ohnishi M, Terajima J, Iyoda S, Morita-Ishihara T, Tateda K, Ishii Y, Saga T, Aoki K, Bonomo RA.

Epidemiol Infect. 2019 Jan;147:e148. doi: 10.1017/S0950268819000426.

44.

Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent.

Barnes MD, Kumar V, Bethel CR, Moussa SH, O'Donnell J, Rutter JD, Good CE, Hujer KM, Hujer AM, Marshall SH, Kreiswirth BN, Richter SS, Rather PN, Jacobs MR, Papp-Wallace KM, van den Akker F, Bonomo RA.

mBio. 2019 Mar 12;10(2). pii: e00159-19. doi: 10.1128/mBio.00159-19.

45.

Beyond Piperacillin-Tazobactam: Cefepime and AAI101 as a Potent β-Lactam-β-Lactamase Inhibitor Combination.

Papp-Wallace KM, Bethel CR, Caillon J, Barnes MD, Potel G, Bajaksouzian S, Rutter JD, Reghal A, Shapiro S, Taracila MA, Jacobs MR, Bonomo RA, Jacqueline C.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00105-19. doi: 10.1128/AAC.00105-19. Print 2019 May.

46.

A Primer on AmpC β-Lactamases: Necessary Knowledge for an Increasingly Multidrug-resistant World.

Tamma PD, Doi Y, Bonomo RA, Johnson JK, Simner PJ; Antibacterial Resistance Leadership Group .

Clin Infect Dis. 2019 Sep 27;69(8):1446-1455. doi: 10.1093/cid/ciz173.

PMID:
30838380
47.

Whole Genome Sequence Analysis of Burkholderia contaminans FFH2055 Strain Reveals the Presence of Putative β-Lactamases.

Degrossi JJ, Merino C, Isasmendi AM, Ibarra LM, Collins C, Bo NE, Papalia M, Fernandez JS, Hernandez CM, Papp-Wallace KM, Bonomo RA, Vazquez MS, Power P, Ramirez MS.

Curr Microbiol. 2019 Apr;76(4):485-494. doi: 10.1007/s00284-019-01653-4. Epub 2019 Feb 19.

48.

Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect.

Ambrose PG, VanScoy BD, Luna BM, Yan J, Ulhaq A, Nielsen TB, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar E, Spellberg B.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00112-19. doi: 10.1128/AAC.00112-19. Print 2019 May.

49.

Shedding of methicillin-resistant Staphylococcus aureus by colonized patients during procedures and patient care activities.

Alhmidi H, Cadnum JL, Koganti S, Jencson AL, Rutter JD, Bonomo RA, Wilson BM, Mayer J, Samore MH, Donskey CJ.

Infect Control Hosp Epidemiol. 2019 Mar;40(3):328-332. doi: 10.1017/ice.2018.342. Epub 2019 Feb 19.

PMID:
30777587
50.

The Clinical and Molecular Epidemiology of CTX-M-9 Group Producing Enterobacteriaceae Infections in Children.

Logan LK, Medernach RL, Domitrovic TN, Rispens JR, Hujer AM, Qureshi NK, Marshall SH, Nguyen DC, Rudin SD, Zheng X, Konda S, Weinstein RA, Bonomo RA.

Infect Dis Ther. 2019 Jun;8(2):243-254. doi: 10.1007/s40121-019-0237-2. Epub 2019 Feb 16.

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