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Items: 20


A high-throughput screening for inhibitors of riboflavin synthase identifies novel antimicrobial compounds to treat brucellosis.

Serer MI, Carrica MDC, Trappe J, López Romero S, Bonomi HR, Klinke S, Cerutti ML, Goldbaum FA.

FEBS J. 2019 Jul;286(13):2522-2535. doi: 10.1111/febs.14829. Epub 2019 Apr 10.


Characterization of folding-sensitive nanobodies as tools to study the expression and quality of protein particle immunogens.

Alzogaray V, Urrutia M, Berguer P, Rossi A, Zylberman V, Pardo R, Bonomi HR, Goldbaum FA.

J Biotechnol. 2019 Mar 10;293:17-23. doi: 10.1016/j.jbiotec.2019.01.001. Epub 2019 Jan 26.


Draft Genome Sequence of Methylobacterium sp. Strain V23, Isolated from Accretion Ice of the Antarctic Subglacial Lake Vostok.

Sapp A, Huguet-Tapia JC, Sánchez-Lamas M, Antelo GT, Primo ED, Rinaldi J, Klinke S, Goldbaum FA, Bonomi HR, Christner BC, Otero LH.

Genome Announc. 2018 Mar 8;6(10). pii: e00145-18. doi: 10.1128/genomeA.00145-18.


Time-Resolved Energetics of Photoprocesses in Prokaryotic Phytochrome-Related Photoreceptors.

Losi A, Bonomi HR, Michael N, Tang K, Zhao KH.

Photochem Photobiol. 2017 May;93(3):733-740. doi: 10.1111/php.12728.


The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists.

Balcazar DE, Vanrell MC, Romano PS, Pereira CA, Goldbaum FA, Bonomi HR, Carrillo C.

PLoS Negl Trop Dis. 2017 Apr 13;11(4):e0005513. doi: 10.1371/journal.pntd.0005513. eCollection 2017 Apr.


ChIP-seq analysis of the LuxR-type regulator VjbR reveals novel insights into the Brucella virulence gene expression network.

Kleinman CL, Sycz G, Bonomi HR, Rodríguez RM, Zorreguieta A, Sieira R.

Nucleic Acids Res. 2017 Jun 2;45(10):5757-5769. doi: 10.1093/nar/gkx165.


Xanthomonas campestris attenuates virulence by sensing light through a bacteriophytochrome photoreceptor.

Bonomi HR, Toum L, Sycz G, Sieira R, Toscani AM, Gudesblat GE, Leskow FC, Goldbaum FA, Vojnov AA, Malamud F.

EMBO Rep. 2016 Nov;17(11):1565-1577. Epub 2016 Sep 12.


Structure of the Full-Length Bacteriophytochrome from the Plant Pathogen Xanthomonas campestris Provides Clues to its Long-Range Signaling Mechanism.

Otero LH, Klinke S, Rinaldi J, Velázquez-Escobar F, Mroginski MA, Fernández López M, Malamud F, Vojnov AA, Hildebrandt P, Goldbaum FA, Bonomi HR.

J Mol Biol. 2016 Sep 25;428(19):3702-20. doi: 10.1016/j.jmb.2016.04.012. Epub 2016 Apr 20.


Brucella spp. Lumazine Synthase Induces a TLR4-Mediated Protective Response against B16 Melanoma in Mice.

Rossi AH, Farias A, Fernández JE, Bonomi HR, Goldbaum FA, Berguer PM.

PLoS One. 2015 May 14;10(5):e0126827. doi: 10.1371/journal.pone.0126827. eCollection 2015.


Extensive Identification of Bacterial Riboflavin Transporters and Their Distribution across Bacterial Species.

Gutiérrez-Preciado A, Torres AG, Merino E, Bonomi HR, Goldbaum FA, García-Angulo VA.

PLoS One. 2015 May 4;10(5):e0126124. doi: 10.1371/journal.pone.0126124. eCollection 2015.


Crystallization and preliminary X-ray characterization of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris pv. campestris.

Klinke S, Otero LH, Rinaldi J, Sosa S, Guimarães BG, Shepard WE, Goldbaum FA, Bonomi HR.

Acta Crystallogr F Struct Biol Commun. 2014 Dec 1;70(Pt 12):1636-9. doi: 10.1107/S2053230X14023243. Epub 2014 Nov 14.


Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility.

Serer MI, Bonomi HR, Guimarães BG, Rossi RC, Goldbaum FA, Klinke S.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1419-34. doi: 10.1107/S1399004714005161. Epub 2014 Apr 30.


Identification and characterization of RibN, a novel family of riboflavin transporters from Rhizobium leguminosarum and other proteobacteria.

García Angulo VA, Bonomi HR, Posadas DM, Serer MI, Torres AG, Zorreguieta Á, Goldbaum FA.

J Bacteriol. 2013 Oct;195(20):4611-9. doi: 10.1128/JB.00644-13. Epub 2013 Aug 9.


Light regulates attachment, exopolysaccharide production, and nodulation in Rhizobium leguminosarum through a LOV-histidine kinase photoreceptor.

Bonomi HR, Posadas DM, Paris G, Carrica Mdel C, Frederickson M, Pietrasanta LI, Bogomolni RA, Zorreguieta A, Goldbaum FA.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12135-40. doi: 10.1073/pnas.1121292109. Epub 2012 Jul 5.


The β-scaffold of the LOV domain of the Brucella light-activated histidine kinase is a key element for signal transduction.

Rinaldi J, Gallo M, Klinke S, Paris G, Bonomi HR, Bogomolni RA, Cicero DO, Goldbaum FA.

J Mol Biol. 2012 Jun 29;420(1-2):112-27. doi: 10.1016/j.jmb.2012.04.006. Epub 2012 Apr 11.


BmaC, a novel autotransporter of Brucella suis, is involved in bacterial adhesion to host cells.

Posadas DM, Ruiz-Ranwez V, Bonomi HR, Martín FA, Zorreguieta A.

Cell Microbiol. 2012 Jun;14(6):965-82. doi: 10.1111/j.1462-5822.2012.01771.x. Epub 2012 Mar 8.


Sensing the dissociation of a polymeric enzyme by means of an engineered intrinsic probe.

Ainciart N, Zylberman V, Craig PO, Nygaard D, Bonomi HR, Cauerhff AA, Goldbaum FA.

Proteins. 2011 Apr;79(4):1079-88. doi: 10.1002/prot.22945. Epub 2011 Jan 18.


The Xanthomonas axonopodis pv. citri flagellum is required for mature biofilm and canker development.

Malamud F, Torres PS, Roeschlin R, Rigano LA, Enrique R, Bonomi HR, Castagnaro AP, Marano MR, Vojnov AA.

Microbiology. 2011 Mar;157(Pt 3):819-829. doi: 10.1099/mic.0.044255-0. Epub 2010 Nov 25.


An atypical riboflavin pathway is essential for Brucella abortus virulence.

Bonomi HR, Marchesini MI, Klinke S, Ugalde JE, Zylberman V, Ugalde RA, Comerci DJ, Goldbaum FA.

PLoS One. 2010 Feb 25;5(2):e9435. doi: 10.1371/journal.pone.0009435.


Structural and kinetic properties of lumazine synthase isoenzymes in the order Rhizobiales.

Klinke S, Zylberman V, Bonomi HR, Haase I, Guimarães BG, Braden BC, Bacher A, Fischer M, Goldbaum FA.

J Mol Biol. 2007 Oct 26;373(3):664-80. Epub 2007 Aug 21.


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