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Items: 1 to 50 of 73

1.

The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells.

Sáez JJ, Diaz J, Ibañez J, Bozo JP, Cabrera Reyes F, Alamo M, Gobert FX, Obino D, Bono MR, Lennon-Duménil AM, Yeaman C, Yuseff MI.

J Cell Biol. 2019 Jul 1;218(7):2247-2264. doi: 10.1083/jcb.201811131. Epub 2019 Jun 13.

PMID:
31197029
2.

In Vitro-Generated Tc17 Cells Present a Memory Phenotype and Serve As a Reservoir of Tc1 Cells In Vivo.

Flores-Santibáñez F, Cuadra B, Fernández D, Rosemblatt MV, Núñez S, Cruz P, Gálvez-Cancino F, Cárdenas JC, Lladser A, Rosemblatt M, Bono MR, Sauma D.

Front Immunol. 2018 Feb 8;9:209. doi: 10.3389/fimmu.2018.00209. eCollection 2018.

3.

Adoptive transfer of autoimmune splenic dendritic cells to lupus-prone mice triggers a B lymphocyte humoral response.

Sauma D, Crisóstomo N, Fuentes C, Gleisner MA, Hidalgo Y, Fuenzalida MJ, Rosemblatt M, Bono MR.

Immunol Res. 2017 Aug;65(4):957-968. doi: 10.1007/s12026-017-8936-9.

4.

The human thymus perivascular space is a functional niche for viral-specific plasma cells.

Nuñez S, Moore C, Gao B, Rogers K, Hidalgo Y, Del Nido PJ, Restaino S, Naka Y, Bhagat G, Madsen JC, Bono MR, Zorn E.

Sci Immunol. 2016 Dec;1(6). pii: eaah4447. doi: 10.1126/sciimmunol.aah4447. Epub 2016 Dec 23.

5.

The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype on DCs.

Doñas C, Carrasco M, Fritz M, Prado C, Tejón G, Osorio-Barrios F, Manríquez V, Reyes P, Pacheco R, Bono MR, Loyola A, Rosemblatt M.

J Autoimmun. 2016 Dec;75:105-117. doi: 10.1016/j.jaut.2016.07.011. Epub 2016 Aug 12.

6.

Purinergic Signaling as a Regulator of Th17 Cell Plasticity.

Fernández D, Flores-Santibáñez F, Neira J, Osorio-Barrios F, Tejón G, Nuñez S, Hidalgo Y, Fuenzalida MJ, Meza D, Ureta G, Lladser A, Pacheco R, Acuña-Castillo C, Guixé V, Quintana FJ, Bono MR, Rosemblatt M, Sauma D.

PLoS One. 2016 Jun 20;11(6):e0157889. doi: 10.1371/journal.pone.0157889. eCollection 2016.

7.

Retinoic Acid as a Modulator of T Cell Immunity.

Bono MR, Tejon G, Flores-Santibañez F, Fernandez D, Rosemblatt M, Sauma D.

Nutrients. 2016 Jun 13;8(6). pii: E349. doi: 10.3390/nu8060349. Review.

8.

Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance.

Ruiz P, Maldonado P, Hidalgo Y, Sauma D, Rosemblatt M, Bono MR.

Front Immunol. 2015 Nov 23;6:596. doi: 10.3389/fimmu.2015.00596. eCollection 2015.

9.

Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation.

Tejón G, Manríquez V, De Calisto J, Flores-Santibáñez F, Hidalgo Y, Crisóstomo N, Fernández D, Sauma D, Mora JR, Bono MR, Rosemblatt M.

Biomed Res Int. 2015;2015:137893. doi: 10.1155/2015/137893. Epub 2015 Oct 25.

10.

Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration.

Chávez MN, Schenck TL, Hopfner U, Centeno-Cerdas C, Somlai-Schweiger I, Schwarz C, Machens HG, Heikenwalder M, Bono MR, Allende ML, Nickelsen J, Egaña JT.

Biomaterials. 2016 Jan;75:25-36. doi: 10.1016/j.biomaterials.2015.10.014. Epub 2015 Oct 8.

PMID:
26474040
11.

Pro-Inflammatory Cytokines in Nasopharyngeal Aspirate From Hospitalized Children With Respiratory Syncytial Virus Infection With or Without Rhinovirus Bronchiolitis, and Use of the Cytokines as Predictors of Illness Severity.

Díaz PV, Valdivia G, Gaggero AA, Bono MR, Zepeda G, Rivas M, Uasapud P, Pinto RA, Boza ML, Guerrero J.

Medicine (Baltimore). 2015 Sep;94(39):e1512. doi: 10.1097/MD.0000000000001512.

12.

CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells.

Flores-Santibáñez F, Fernández D, Meza D, Tejón G, Vargas L, Varela-Nallar L, Arredondo S, Guixé V, Rosemblatt M, Bono MR, Sauma D.

Immunology. 2015 Dec;146(4):582-94. doi: 10.1111/imm.12529. Epub 2015 Sep 29.

13.

CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression.

Bono MR, Fernández D, Flores-Santibáñez F, Rosemblatt M, Sauma D.

FEBS Lett. 2015 Nov 14;589(22):3454-60. doi: 10.1016/j.febslet.2015.07.027. Epub 2015 Jul 29. Review.

14.

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.

Moore C, Tejon G, Fuentes C, Hidalgo Y, Bono MR, Maldonado P, Fernandez R, Wood KJ, Fierro JA, Rosemblatt M, Sauma D, Bushell A.

Eur J Immunol. 2015 Feb;45(2):452-63. doi: 10.1002/eji.201444743. Epub 2014 Dec 2.

15.

Functional analysis reveals angiogenic potential of human mesenchymal stem cells from Wharton's jelly in dermal regeneration.

Edwards SS, Zavala G, Prieto CP, Elliott M, Martínez S, Egaña JT, Bono MR, Palma V.

Angiogenesis. 2014 Oct;17(4):851-66. doi: 10.1007/s10456-014-9432-7. Epub 2014 Apr 13.

PMID:
24728929
16.

[Levels of inflammatory cytokines and plasma cortisol in respiratory syncytial virus bronchiolitis].

Díaz PV, Gaggero AA, Pinto RA, Mamani R, Uasapud PA, Bono MR.

Rev Med Chil. 2013 May;141(5):574-81. doi: 10.4067/S0034-98872013000500004. Spanish.

17.

Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons.

Gonzalez-Silva C, Vera J, Bono MR, González-Billault C, Baxter B, Hansen A, Lopez R, Gibson EA, Restrepo D, Bacigalupo J.

PLoS One. 2013 Jul 9;8(7):e69295. doi: 10.1371/journal.pone.0069295. Print 2013.

18.

Transplant tolerance: new insights and strategies for long-term allograft acceptance.

Ruiz P, Maldonado P, Hidalgo Y, Gleisner A, Sauma D, Silva C, Saez JJ, Nuñez S, Rosemblatt M, Bono MR.

Clin Dev Immunol. 2013;2013:210506. doi: 10.1155/2013/210506. Epub 2013 May 12. Review.

19.

Trichostatin A promotes the generation and suppressive functions of regulatory T cells.

Doñas C, Fritz M, Manríquez V, Tejón G, Bono MR, Loyola A, Rosemblatt M.

Clin Dev Immunol. 2013;2013:679804. doi: 10.1155/2013/679804. Epub 2013 May 8.

20.

Epithelial control of the human pDC response to extracellular bacteria.

Michea P, Vargas P, Donnadieu MH, Rosemblatt M, Bono MR, Duménil G, Soumelis V.

Eur J Immunol. 2013 May;43(5):1264-73. doi: 10.1002/eji.201242990. Epub 2013 Mar 6.

21.

Dendritic and stromal cells from the spleen of lupic mice present phenotypic and functional abnormalities.

Gleisner MA, Reyes P, Alfaro J, Solanes P, Simon V, Crisostomo N, Sauma D, Rosemblatt M, Bono MR.

Mol Immunol. 2013 Jul;54(3-4):423-34. doi: 10.1016/j.molimm.2013.01.011. Epub 2013 Feb 21.

PMID:
23428837
22.

T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour.

Nuñez S, Saez JJ, Fernandez D, Flores-Santibañez F, Alvarez K, Tejon G, Ruiz P, Maldonado P, Hidalgo Y, Manriquez V, Bono MR, Rosemblatt M, Sauma D.

Immunology. 2013 May;139(1):61-71. doi: 10.1111/imm.12055.

23.

Increased expression of the glucocorticoid receptor β in infants with RSV bronchiolitis.

Diaz PV, Pinto RA, Mamani R, Uasapud PA, Bono MR, Gaggero AA, Guerrero J, Goecke A.

Pediatrics. 2012 Oct;130(4):e804-11. doi: 10.1542/peds.2012-0160. Epub 2012 Sep 24.

PMID:
23008453
24.

Notch signalling regulates cytokine production by CD8+ and CD4+ T cells.

Sauma D, Ramirez A, Alvarez K, Rosemblatt M, Bono MR.

Scand J Immunol. 2012 Apr;75(4):389-400. doi: 10.1111/j.1365-3083.2012.02673.x.

25.

T-cell homing to the gut mucosa: general concepts and methodological considerations.

De Calisto J, Villablanca EJ, Wang S, Bono MR, Rosemblatt M, Mora JR.

Methods Mol Biol. 2012;757:411-34. doi: 10.1007/978-1-61779-166-6_24.

PMID:
21909925
26.

Retinoic acid generates regulatory T cells in experimental transplantation.

Moore C, Fuentes C, Sauma D, Morales J, Bono MR, Rosemblatt M, Fierro JA.

Transplant Proc. 2011 Jul-Aug;43(6):2334-7. doi: 10.1016/j.transproceed.2011.06.057. Review.

PMID:
21839265
27.

Delivery of alloantigens via apoptotic cells generates dendritic cells with an immature tolerogenic phenotype.

Gleisner MA, Rosemblatt M, Fierro JA, Bono MR.

Transplant Proc. 2011 Jul-Aug;43(6):2325-33. doi: 10.1016/j.transproceed.2011.06.007.

PMID:
21839264
28.

MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells.

Villablanca EJ, Wang S, de Calisto J, Gomes DC, Kane MA, Napoli JL, Blaner WS, Kagechika H, Blomhoff R, Rosemblatt M, Bono MR, von Andrian UH, Mora JR.

Gastroenterology. 2011 Jul;141(1):176-85. doi: 10.1053/j.gastro.2011.04.010. Epub 2011 Apr 16.

29.

Differential regulation of Notch ligands in dendritic cells upon interaction with T helper cells.

Sauma D, Espejo P, Ramirez A, Fierro A, Rosemblatt M, Bono MR.

Scand J Immunol. 2011 Jul;74(1):62-70. doi: 10.1111/j.1365-3083.2011.02541.x.

30.

Cyclosporin A-treated dendritic cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation.

Pino-Lagos K, Michea P, Sauma D, Alba A, Morales J, Bono MR, Fierro A, Rosemblatt M.

Biol Res. 2010;43(3):333-7. doi: /S0716-97602010000300010. Epub 2010 Nov 30.

31.

Dendritic cells and B cells cooperate in the generation of CD4(+)CD25(+)FOXP3(+) allogeneic T cells.

Moore C, Sauma D, Reyes PA, Morales J, Rosemblatt M, Bono MR, Fierro JA.

Transplant Proc. 2010 Jan-Feb;42(1):371-5. doi: 10.1016/j.transproceed.2009.12.044.

PMID:
20172352
32.

Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.

Jørgensen TN, Alfaro J, Enriquez HL, Jiang C, Loo WM, Atencio S, Bupp MR, Mailloux CM, Metzger T, Flannery S, Rozzo SJ, Kotzin BL, Rosemblatt M, Bono MR, Erickson LD.

J Immunol. 2010 Jan 15;184(2):775-86. doi: 10.4049/jimmunol.0901322. Epub 2009 Dec 16.

33.

Transforming growth factor-beta and all-trans retinoic acid generate ex vivo transgenic regulatory T cells with intestinal homing receptors.

Moore C, Sauma D, Morales J, Bono MR, Rosemblatt M, Fierro JA.

Transplant Proc. 2009 Jul-Aug;41(6):2670-2. doi: 10.1016/j.transproceed.2009.06.130.

PMID:
19715998
34.

Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation.

Elgueta R, Tobar JA, Shoji KF, De Calisto J, Kalergis AM, Bono MR, Rosemblatt M, Sáez JC.

J Immunol. 2009 Jul 1;183(1):277-84. doi: 10.4049/jimmunol.0801854.

35.

Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain.

Faure-André G, Vargas P, Yuseff MI, Heuzé M, Diaz J, Lankar D, Steri V, Manry J, Hugues S, Vascotto F, Boulanger J, Raposo G, Bono MR, Rosemblatt M, Piel M, Lennon-Duménil AM.

Science. 2008 Dec 12;322(5908):1705-10. doi: 10.1126/science.1159894.

36.

Alemtuzumab induction in kidney transplantation: clinical results and impact on T-regulatory cells.

Morales J, Bono MR, Fierro A, Iñiguez R, Zehnder C, Rosemblatt M, Calabran L, Herzog C, Benavente D, Aguiló J, Pefaur J, Alba A, Ferrario M, Simon W, Contreras L, Buckel E.

Transplant Proc. 2008 Nov;40(9):3223-8. doi: 10.1016/j.transproceed.2008.03.066.

PMID:
19010240
37.

Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells.

Elgueta R, Sepulveda FE, Vilches F, Vargas L, Mora JR, Bono MR, Rosemblatt M.

J Immunol. 2008 May 15;180(10):6501-7.

38.

Generation of dendritic cells with regulatory properties.

Ureta G, Osorio F, Morales J, Rosemblatt M, Bono MR, Fierro JA.

Transplant Proc. 2007 Apr;39(3):633-7.

PMID:
17445563
39.

Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione.

Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, van Zundert B, Bono MR, Oñate SA, Bustamante M, Cárcamo JG, Rivas CI, Vera JC.

J Biol Chem. 2007 May 25;282(21):15506-15. Epub 2007 Apr 2.

40.

The essential role of chemokines in the selective regulation of lymphocyte homing.

Bono MR, Elgueta R, Sauma D, Pino K, Osorio F, Michea P, Fierro A, Rosemblatt M.

Cytokine Growth Factor Rev. 2007 Feb-Apr;18(1-2):33-43. Epub 2007 Feb 26. Review.

PMID:
17324605
41.

T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol.

Pinto RA, Arredondo SM, Bono MR, Gaggero AA, Díaz PV.

Pediatrics. 2006 May;117(5):e878-86. Epub 2006 Apr 17.

PMID:
16618789
42.

Immunization with antigen-pulsed dendritic cells significantly improves the immune response to weak self-antigens.

Vargas P, Cortés C, Vargas L, Rosemblatt M, Bono MR.

Immunobiology. 2006;211(1-2):29-36. Epub 2006 Jan 18.

PMID:
16446168
43.

Lymphoid B cells induce NF-kappaB activation in high endothelial cells from human tonsils.

Naves R, Reyes LI, Rosemblatt M, Jacobelli S, González A, Bono MR.

Int Immunol. 2006 Feb;18(2):259-67. Epub 2005 Dec 22.

PMID:
16373365
44.

Interleukin-4 selectively inhibits interleukin-2 secretion by lipopolysaccharide-activated dendritic cells.

Sauma D, Michea P, Lennon-Duménil AM, Fierro A, Morales J, Rosemblatt M, Bono MR.

Scand J Immunol. 2004 Feb;59(2):183-9.

45.

Functional consequences of immune cell adhesion to endothelial cells.

Rosemblatt M, Bono MR.

Curr Pharm Des. 2004;10(2):109-20. Review.

PMID:
14754391
46.

Cyclosporine preconditions dendritic cells during differentiation and reduces IL-2 and IL-12 production following activation: a potential tolerogenic effect.

Sauma D, Fierro A, Mora JR, Lennon-Duménil AM, Bono MR, Rosemblatt M, Morales J.

Transplant Proc. 2003 Nov;35(7):2515-7.

PMID:
14611999
47.

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells.

Mora JR, Bono MR, Manjunath N, Weninger W, Cavanagh LL, Rosemblatt M, Von Andrian UH.

Nature. 2003 Jul 3;424(6944):88-93.

PMID:
12840763
49.

Dendritic cells and the mode of action of anticalcineurinic drugs: an integrating hypothesis.

Fierro A, Mora JR, Bono MR, Morales J, Buckel E, Sauma D, Rosemblatt M.

Nephrol Dial Transplant. 2003 Mar;18(3):467-8; discussion 469-70. Review. No abstract available.

PMID:
12584263
50.

Low-dose prednisone accounts for a transient reduction on CD4+ and CD8+ T cells in renal transplant patients under triple therapy.

Sauma D, Mora JR, Fierro A, Morales J, Herzog C, Buckel E, Rosemblatt M, Bono MR.

Transplant Proc. 2002 Dec;34(8):3183-4. No abstract available.

PMID:
12493413

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