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Items: 1 to 50 of 79

1.

Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies.

Perrot I, Michaud HA, Giraudon-Paoli M, Augier S, Docquier A, Gros L, Courtois R, Déjou C, Jecko D, Becquart O, Rispaud-Blanc H, Gauthier L, Rossi B, Chanteux S, Gourdin N, Amigues B, Roussel A, Bensussan A, Eliaou JF, Bastid J, Romagné F, Morel Y, Narni-Mancinelli E, Vivier E, Paturel C, Bonnefoy N.

Cell Rep. 2019 May 21;27(8):2411-2425.e9. doi: 10.1016/j.celrep.2019.04.091.

2.

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer.

Combès E, Andrade AF, Tosi D, Michaud HA, Coquel F, Garambois V, Desigaud D, Jarlier M, Coquelle A, Pasero P, Bonnefoy N, Moreaux J, Martineau P, Del Rio M, Beijersbergen RL, Vezzio-Vie N, Gongora C.

Cancer Res. 2019 Jun 1;79(11):2933-2946. doi: 10.1158/0008-5472.CAN-18-2807. Epub 2019 Apr 15.

PMID:
30987998
3.

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies.

Ashraf Y, Mansouri H, Laurent-Matha V, Alcaraz LB, Roger P, Guiu S, Derocq D, Robin G, Michaud HA, Delpech H, Jarlier M, Pugnière M, Robert B, Puel A, Martin L, Landomiel F, Bourquard T, Achour O, Fruitier-Arnaudin I, Pichard A, Deshayes E, Turtoi A, Poupon A, Simony-Lafontaine J, Boissière-Michot F, Pirot N, Bernex F, Jacot W, du Manoir S, Theillet C, Pouget JP, Navarro-Teulon I, Bonnefoy N, Pèlegrin A, Chardès T, Martineau P, Liaudet-Coopman E.

J Immunother Cancer. 2019 Feb 4;7(1):29. doi: 10.1186/s40425-019-0498-z.

4.

Personal history of infections and immunotherapy: Unexpected links and possible therapeutic opportunities.

Jacqueline C, Bonnefoy N, Charrière GM, Thomas F, Roche B.

Oncoimmunology. 2018 Jun 11;7(8):e1466019. doi: 10.1080/2162402X.2018.1466019. eCollection 2018. Review.

5.

Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance.

Durand M, Dubois F, Dejou C, Durand E, Danger R, Chesneau M, Brosseau C, Guerif P, Soulillou JP, Degauque N, Eliaou JF, Giral M, Bonnefoy N, Brouard S.

Kidney Int. 2018 May;93(5):1154-1164. doi: 10.1016/j.kint.2017.12.004. Epub 2018 Feb 15.

PMID:
29455908
6.

The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway.

Laprevotte E, Cochaud S, du Manoir S, Lapierre M, Dejou C, Philippe M, Giustiniani J, Frewer KA, Sanders AJ, Jiang WG, Michaud HA, Colombo PE, Bensussan A, Alberici G, Bastid J, Eliaou JF, Bonnefoy N.

Oncotarget. 2017 Dec 6;8(69):113360-113372. doi: 10.18632/oncotarget.23008. eCollection 2017 Dec 26.

7.

IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population.

Barjon C, Michaud HA, Fages A, Dejou C, Zampieri A, They L, Gennetier A, Sanchez F, Gros L, Eliaou JF, Bonnefoy N, Lafont V.

Oncoimmunology. 2017 Oct 4;7(1):e1379642. doi: 10.1080/2162402X.2017.1379642. eCollection 2017.

8.

PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody.

They L, Michaud HA, Becquart O, Lafont V, Guillot B, Boissière-Michot F, Jarlier M, Mollevi C, Eliaou JF, Bonnefoy N, Gros L.

Oncoimmunology. 2017 Jul 20;6(10):e1353857. doi: 10.1080/2162402X.2017.1353857. eCollection 2017.

9.

Immune signatures of protective spleen memory CD8 T cells.

Brinza L, Djebali S, Tomkowiak M, Mafille J, Loiseau C, Jouve PE, de Bernard S, Buffat L, Lina B, Ottmann M, Rosa-Calatrava M, Schicklin S, Bonnefoy N, Lauvau G, Grau M, Wencker M, Arpin C, Walzer T, Leverrier Y, Marvel J.

Sci Rep. 2016 Nov 24;6:37651. doi: 10.1038/srep37651.

10.

Loss of Msp1p in Schizosaccharomyces pombe induces a ROS-dependent nuclear mutator phenotype that affects mitochondrial fission genes.

Delerue T, Khosrobakhsh F, Daloyau M, Emorine LJ, Dedieu A, Herbert CJ, Bonnefoy N, Arnauné-Pelloquin L, Belenguer P.

FEBS Lett. 2016 Oct;590(20):3544-3558. doi: 10.1002/1873-3468.12432. Epub 2016 Oct 11.

11.

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen.

Limagne E, Euvrard R, Thibaudin M, Rébé C, Derangère V, Chevriaux A, Boidot R, Végran F, Bonnefoy N, Vincent J, Bengrine-Lefevre L, Ladoire S, Delmas D, Apetoh L, Ghiringhelli F.

Cancer Res. 2016 Sep 15;76(18):5241-52. doi: 10.1158/0008-5472.CAN-15-3164. Epub 2016 Aug 5.

12.

Ribosome recycling defects modify the balance between the synthesis and assembly of specific subunits of the oxidative phosphorylation complexes in yeast mitochondria.

Ostojić J, Panozzo C, Bourand-Plantefol A, Herbert CJ, Dujardin G, Bonnefoy N.

Nucleic Acids Res. 2016 Jul 8;44(12):5785-97. doi: 10.1093/nar/gkw490. Epub 2016 Jun 1.

13.

CD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression.

Bonnefoy N, Bastid J, Alberici G, Bensussan A, Eliaou JF.

Oncoimmunology. 2015 Feb 3;4(5):e1003015. eCollection 2015 May.

14.

IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells.

Mombelli S, Cochaud S, Merrouche Y, Garbar C, Antonicelli F, Laprevotte E, Alberici G, Bonnefoy N, Eliaou JF, Bastid J, Bensussan A, Giustiniani J.

Sci Rep. 2015 Jul 8;5:11874. doi: 10.1038/srep11874.

15.

Tumor antigen-targeting monoclonal antibody-based immunotherapy: Orchestrating combined strategies for the development of long-term antitumor immunity.

Michaud HA, Eliaou JF, Lafont V, Bonnefoy N, Gros L.

Oncoimmunology. 2014 Dec 13;3(9):e955684. eCollection 2014 Oct. Review.

16.

Plasticity of γδ T Cells: Impact on the Anti-Tumor Response.

Lafont V, Sanchez F, Laprevotte E, Michaud HA, Gros L, Eliaou JF, Bonnefoy N.

Front Immunol. 2014 Dec 8;5:622. doi: 10.3389/fimmu.2014.00622. eCollection 2014. Review.

17.

Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity.

Bastid J, Regairaz A, Bonnefoy N, Déjou C, Giustiniani J, Laheurte C, Cochaud S, Laprevotte E, Funck-Brentano E, Hemon P, Gros L, Bec N, Larroque C, Alberici G, Bensussan A, Eliaou JF.

Cancer Immunol Res. 2015 Mar;3(3):254-65. doi: 10.1158/2326-6066.CIR-14-0018. Epub 2014 Nov 17.

18.

Lymphocyte-derived interleukin-17A adds another brick in the wall of inflammation-induced breast carcinogenesis.

Bastid J, Bonnefoy N, Eliaou JF, Bensussan A.

Oncoimmunology. 2014 Mar 27;3:e28273. eCollection 2014.

19.

Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737.

Mathieu AL, Sperandio O, Pottiez V, Balzarin S, Herlédan A, Elkaïm JO, Fogeron ML, Piveteau C, Dassonneville S, Deprez B, Villoutreix BO, Bonnefoy N, Leroux F.

J Biomol Screen. 2014 Aug;19(7):1035-46. doi: 10.1177/1087057114534070. Epub 2014 May 8.

PMID:
24809353
20.

The emerging role of Twist proteins in hematopoietic cells and hematological malignancies.

Merindol N, Riquet A, Szablewski V, Eliaou JF, Puisieux A, Bonnefoy N.

Blood Cancer J. 2014 Apr 25;4:e206. doi: 10.1038/bcj.2014.22. Review. Erratum in: Blood Cancer J. 2014 Oct;4:e254.

21.

Reply: To PMID 23666743.

Belot A, Brognard J, Crow YJ, Bonnefoy N.

Arthritis Rheumatol. 2014 Jan;66(1):229-30. doi: 10.1002/art.38234. No abstract available.

22.

IL-17A is produced by breast cancer TILs and promotes chemoresistance and proliferation through ERK1/2.

Cochaud S, Giustiniani J, Thomas C, Laprevotte E, Garbar C, Savoye AM, Curé H, Mascaux C, Alberici G, Bonnefoy N, Eliaou JF, Bensussan A, Bastid J.

Sci Rep. 2013 Dec 9;3:3456. doi: 10.1038/srep03456.

23.

Does the study of genetic interactions help predict the function of mitochondrial proteins in Saccharomyces cerevisiae?

Ostojić J, Glatigny A, Herbert CJ, Dujardin G, Bonnefoy N.

Biochimie. 2014 May;100:27-37. doi: 10.1016/j.biochi.2013.11.004. Epub 2013 Nov 19. Review.

PMID:
24262604
24.

Yeast PPR proteins, watchdogs of mitochondrial gene expression.

Herbert CJ, Golik P, Bonnefoy N.

RNA Biol. 2013;10(9):1477-94. doi: 10.4161/rna.25392. Epub 2013 Jun 18.

25.

Dynamo threshold detection in the von Kármán sodium experiment.

Miralles S, Bonnefoy N, Bourgoin M, Odier P, Pinton JF, Plihon N, Verhille G, Boisson J, Daviaud F, Dubrulle B.

Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Jul;88(1):013002. Epub 2013 Jul 8.

PMID:
23944544
26.

Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria.

Dujeancourt L, Richter R, Chrzanowska-Lightowlers ZM, Bonnefoy N, Herbert CJ.

Mitochondrion. 2013 Nov;13(6):871-80. doi: 10.1016/j.mito.2013.07.115. Epub 2013 Jul 24.

27.

Protein kinase cδ deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation.

Belot A, Kasher PR, Trotter EW, Foray AP, Debaud AL, Rice GI, Szynkiewicz M, Zabot MT, Rouvet I, Bhaskar SS, Daly SB, Dickerson JE, Mayer J, O'Sullivan J, Juillard L, Urquhart JE, Fawdar S, Marusiak AA, Stephenson N, Waszkowycz B, W Beresford M, Biesecker LG, C M Black G, René C, Eliaou JF, Fabien N, Ranchin B, Cochat P, Gaffney PM, Rozenberg F, Lebon P, Malcus C, Crow YJ, Brognard J, Bonnefoy N.

Arthritis Rheum. 2013 Aug;65(8):2161-71. doi: 10.1002/art.38008.

28.

Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle provides insights into the evolution of the cotranslational insertion systems.

Funes S, Westerburg H, Jaimes-Miranda F, Woellhaf MW, Aguilar-Lopez JL, Janßen L, Bonnefoy N, Kauff F, Herrmann JM.

FEBS J. 2013 Feb;280(3):904-15. doi: 10.1111/febs.12082. Epub 2013 Jan 2.

29.

Mitochondrial protein synthesis: efficiency and accuracy.

Kehrein K, Bonnefoy N, Ott M.

Antioxid Redox Signal. 2013 Dec 1;19(16):1928-39. doi: 10.1089/ars.2012.4896. Epub 2013 Jan 22. Review.

PMID:
23088322
30.

Synthesis and biological activities of polyquinoline derivatives: new Bcl-2 family protein modulators.

Saugues E, Debaud AL, Anizon F, Bonnefoy N, Moreau P.

Eur J Med Chem. 2012 Nov;57:112-25. doi: 10.1016/j.ejmech.2012.09.012. Epub 2012 Sep 17.

PMID:
23047228
31.

Co-evolution of mitochondrial tRNA import and codon usage determines translational efficiency in the green alga Chlamydomonas.

Salinas T, Duby F, Larosa V, Coosemans N, Bonnefoy N, Motte P, Maréchal-Drouard L, Remacle C.

PLoS Genet. 2012 Sep;8(9):e1002946. doi: 10.1371/journal.pgen.1002946. Epub 2012 Sep 20.

32.

The Cbp3-Cbp6 complex coordinates cytochrome b synthesis with bc(1) complex assembly in yeast mitochondria.

Gruschke S, Römpler K, Hildenbeutel M, Kehrein K, Kühl I, Bonnefoy N, Ott M.

J Cell Biol. 2012 Oct 1;199(1):137-50. doi: 10.1083/jcb.201206040. Epub 2012 Sep 24.

33.

NOD1 cooperates with TLR2 to enhance T cell receptor-mediated activation in CD8 T cells.

Mercier BC, Ventre E, Fogeron ML, Debaud AL, Tomkowiak M, Marvel J, Bonnefoy N.

PLoS One. 2012;7(7):e42170. doi: 10.1371/journal.pone.0042170. Epub 2012 Jul 27.

34.

ENTPD1/CD39 is a promising therapeutic target in oncology.

Bastid J, Cottalorda-Regairaz A, Alberici G, Bonnefoy N, Eliaou JF, Bensussan A.

Oncogene. 2013 Apr 4;32(14):1743-51. doi: 10.1038/onc.2012.269. Epub 2012 Jul 2. Review.

PMID:
22751118
35.

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

Macaire H, Riquet A, Moncollin V, Biémont-Trescol MC, Duc Dodon M, Hermine O, Debaud AL, Mahieux R, Mesnard JM, Pierre M, Gazzolo L, Bonnefoy N, Valentin H.

J Biol Chem. 2012 Jun 15;287(25):21357-70. doi: 10.1074/jbc.M112.340992. Epub 2012 May 2.

36.

Experimental observation of spatially localized dynamo magnetic fields.

Gallet B, Aumaître S, Boisson J, Daviaud F, Dubrulle B, Bonnefoy N, Bourgoin M, Odier P, Pinton JF, Plihon N, Verhille G, Fauve S, Pétrélis F.

Phys Rev Lett. 2012 Apr 6;108(14):144501. Epub 2012 Apr 2.

PMID:
22540795
37.

Control of protein synthesis in yeast mitochondria: the concept of translational activators.

Herrmann JM, Woellhaf MW, Bonnefoy N.

Biochim Biophys Acta. 2013 Feb;1833(2):286-94. doi: 10.1016/j.bbamcr.2012.03.007. Epub 2012 Mar 16. Review.

38.
39.

Reconstruction of a human mitochondrial complex I mutation in the unicellular green alga Chlamydomonas.

Larosa V, Coosemans N, Motte P, Bonnefoy N, Remacle C.

Plant J. 2012 Jun;70(5):759-68. doi: 10.1111/j.1365-313X.2012.04912.x. Epub 2012 Mar 8.

40.

A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression.

Kühl I, Dujeancourt L, Gaisne M, Herbert CJ, Bonnefoy N.

Nucleic Acids Res. 2011 Oct;39(18):8029-41. doi: 10.1093/nar/gkr511. Epub 2011 Jul 3.

41.

Genetic and functional interactions between the mitochondrial outer membrane proteins Tom6 and Sam37.

Dukanovic J, Dimmer KS, Bonnefoy N, Krumpe K, Rapaport D.

Mol Cell Biol. 2009 Nov;29(22):5975-88. doi: 10.1128/MCB.00069-09. Epub 2009 Sep 21.

42.

The human mitochondrial ribosome recycling factor is essential for cell viability.

Rorbach J, Richter R, Wessels HJ, Wydro M, Pekalski M, Farhoud M, Kühl I, Gaisne M, Bonnefoy N, Smeitink JA, Lightowlers RN, Chrzanowska-Lightowlers ZM.

Nucleic Acids Res. 2008 Oct;36(18):5787-99. doi: 10.1093/nar/gkn576. Epub 2008 Sep 9.

43.

Roles of Oxa1-related inner-membrane translocases in assembly of respiratory chain complexes.

Bonnefoy N, Fiumera HL, Dujardin G, Fox TD.

Biochim Biophys Acta. 2009 Jan;1793(1):60-70. doi: 10.1016/j.bbamcr.2008.05.004. Epub 2008 May 15. Review.

44.

Directed alteration of Saccharomyces cerevisiae mitochondrial DNA by biolistic transformation and homologous recombination.

Bonnefoy N, Fox TD.

Methods Mol Biol. 2007;372:153-66. doi: 10.1007/978-1-59745-365-3_11.

45.

Studying mitochondria in an attractive model: Schizosaccharomyces pombe.

Chiron S, Gaisne M, Guillou E, Belenguer P, Clark-Walker GD, Bonnefoy N.

Methods Mol Biol. 2007;372:91-105. doi: 10.1007/978-1-59745-365-3_7.

PMID:
18314720
46.

mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG.

Soleimanpour-Lichaei HR, Kühl I, Gaisne M, Passos JF, Wydro M, Rorbach J, Temperley R, Bonnefoy N, Tate W, Lightowlers R, Chrzanowska-Lightowlers Z.

Mol Cell. 2007 Sep 7;27(5):745-57.

47.

Genetic transformation of Saccharomyces cerevisiae and Chlamydomonas reinhardtii mitochondria.

Bonnefoy N, Remacle C, Fox TD.

Methods Cell Biol. 2007;80:525-48. Review. No abstract available.

PMID:
17445712
48.

RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.

Wiesenberger G, Speer F, Haller G, Bonnefoy N, Schleiffer A, Schafer B.

J Mol Biol. 2007 Mar 30;367(3):681-91. Epub 2007 Jan 10.

PMID:
17292401

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