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Items: 1 to 50 of 312

1.

Acute Hepatic Porphyrias: Review and Recent Progress.

Wang B, Rudnick S, Cengia B, Bonkovsky HL.

Hepatol Commun. 2018 Dec 20;3(2):193-206. doi: 10.1002/hep4.1297. eCollection 2019 Feb. Review.

2.

Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.

Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PH, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J; US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group.

PLoS One. 2019 Feb 11;14(2):e0212394. doi: 10.1371/journal.pone.0212394. eCollection 2019.

3.

Benefits of prophylactic heme therapy in severe acute intermittent porphyria.

Yarra P, Faust D, Bennett M, Rudnick S, Bonkovsky HL.

Mol Genet Metab Rep. 2019 Jan 30;19:100450. doi: 10.1016/j.ymgmr.2019.01.002. eCollection 2019 Jun.

4.

Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.

Sardh E, Harper P, Balwani M, Stein P, Rees D, Bissell DM, Desnick R, Parker C, Phillips J, Bonkovsky HL, Vassiliou D, Penz C, Chan-Daniels A, He Q, Querbes W, Fitzgerald K, Kim JB, Garg P, Vaishnaw A, Simon AR, Anderson KE.

N Engl J Med. 2019 Feb 7;380(6):549-558. doi: 10.1056/NEJMoa1807838.

PMID:
30726693
5.

Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.

Pulgar VM, Yasuda M, Gan L, Desnick RJ, Bonkovsky HL.

Mol Genet Metab. 2019 Jan 7. pii: S1096-7192(18)30583-3. doi: 10.1016/j.ymgme.2019.01.005. [Epub ahead of print]

PMID:
30639047
6.

Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.

Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PJ, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J; US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group.

PLoS One. 2018 Oct 25;13(10):e0206389. doi: 10.1371/journal.pone.0206389. eCollection 2018. Erratum in: PLoS One. 2019 Feb 11;14(2):e0212394.

7.

miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling.

Sendi H, Mead I, Wan M, Mehrab-Mohseni M, Koch K, Atala A, Bonkovsky HL, Bishop CE.

PLoS One. 2018 Jul 19;13(7):e0200847. doi: 10.1371/journal.pone.0200847. eCollection 2018.

8.

Peripheral Neuropathy and the Ceruloplasmin Gene.

Hines MC Jr, Bonkovsky HL, Rudnick SR, Mhoon JT.

Ann Intern Med. 2018 Jun 19;168(12):894-895. doi: 10.7326/L17-0621. Epub 2018 Feb 27. No abstract available.

PMID:
29482220
9.

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort.

Church RJ, Kullak-Ublick GA, Aubrecht J, Bonkovsky HL, Chalasani N, Fontana RJ, Goepfert JC, Hackman F, King NMP, Kirby S, Kirby P, Marcinak J, Ormarsdottir S, Schomaker SJ, Schuppe-Koistinen I, Wolenski F, Arber N, Merz M, Sauer JM, Andrade RJ, van Bömmel F, Poynard T, Watkins PB.

Hepatology. 2019 Feb;69(2):760-773. doi: 10.1002/hep.29802. Epub 2018 Jun 27.

PMID:
29357190
10.

Porphyria.

Bissell DM, Anderson KE, Bonkovsky HL.

N Engl J Med. 2017 Nov 23;377(21):2101. doi: 10.1056/NEJMc1712682. No abstract available.

11.

Reply.

Wang B, Balwani M, Bonkovsky HL, Anderson KE, Bloomer JR, Bissell DM, Phillips JD, Desnick RJ; Porphyrias Consortium of the Rare Diseases Clinical Research Network.

Hepatology. 2017 Nov 21. doi: 10.1002/hep.29674. [Epub ahead of print] No abstract available.

PMID:
29159969
12.

BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma.

Ma J, Zeng S, Zhang Y, Deng G, Qu Y, Guo C, Yin L, Han Y, Cai C, Li Y, Wang G, Bonkovsky HL, Shen H.

Cancer Lett. 2017 Dec 28;411:117-129. doi: 10.1016/j.canlet.2017.09.041. Epub 2017 Oct 4.

PMID:
28987388
13.

Porphyria.

Bissell DM, Anderson KE, Bonkovsky HL.

N Engl J Med. 2017 Aug 31;377(9):862-872. doi: 10.1056/NEJMra1608634. Review. No abstract available.

PMID:
28854095
14.

Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria.

Balwani M, Naik H, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Overbey JR, Wang B, Singal AK, Liu LU, Desnick RJ.

JAMA Dermatol. 2017 Aug 1;153(8):789-796. doi: 10.1001/jamadermatol.2017.1557.

15.

Acute hepatic porphyrias: Recommendations for evaluation and long-term management.

Balwani M, Wang B, Anderson KE, Bloomer JR, Bissell DM, Bonkovsky HL, Phillips JD, Desnick RJ; Porphyrias Consortium of the Rare Diseases Clinical Research Network.

Hepatology. 2017 Oct;66(4):1314-1322. doi: 10.1002/hep.29313. Epub 2017 Sep 4. Review.

16.

Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury.

Suzuki A, Barnhart H, Gu J, Bonkovsky HL, Tillmann HL, Fontana RJ, Kleiner DE; Drug-induced Liver Injury Network (DILIN).

Liver Int. 2017 Nov;37(11):1723-1730. doi: 10.1111/liv.13380. Epub 2017 Mar 2.

17.

Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response.

Whritenour J, Ko M, Zong Q, Wang J, Tartaro K, Schneider P, Olson E, Van Volkenburg M, Serrano J, Hayashi P, Fontana R, Chalasani N, Bonkovsky HL.

J Immunotoxicol. 2017 Dec;14(1):31-38. doi: 10.1080/1547691X.2016.1254305.

18.

BMP4 promotes metastasis of hepatocellular carcinoma by an induction of epithelial-mesenchymal transition via upregulating ID2.

Zeng S, Zhang Y, Ma J, Deng G, Qu Y, Guo C, Han Y, Yin L, Cai C, Li Y, Wang G, Bonkovsky HL, Shen H.

Cancer Lett. 2017 Apr 1;390:67-76. doi: 10.1016/j.canlet.2016.12.042. Epub 2017 Jan 16.

PMID:
28093286
19.

Advances in the management of erythropoietic protoporphyria - role of afamelanotide.

Lane AM, McKay JT, Bonkovsky HL.

Appl Clin Genet. 2016 Dec 12;9:179-189. doi: 10.2147/TACG.S122030. eCollection 2016. Review.

20.

Clinical presentations and outcomes of bile duct loss caused by drugs and herbal and dietary supplements.

Bonkovsky HL, Kleiner DE, Gu J, Odin JA, Russo MW, Navarro VM, Fontana RJ, Ghabril MS, Barnhart H, Hoofnagle JH; U.S. Drug Induced Liver Injury Network Investigators.

Hepatology. 2017 Apr;65(4):1267-1277. doi: 10.1002/hep.28967. Epub 2017 Feb 7.

21.

Profiles of miRNAs in serum in severe acute drug induced liver injury and their prognostic significance.

Russo MW, Steuerwald N, Norton HJ, Anderson WE, Foureau D, Chalasani N, Fontana RJ, Watkins PB, Serrano J, Bonkovsky HL.

Liver Int. 2017 May;37(5):757-764. doi: 10.1111/liv.13312. Epub 2016 Nov 29.

22.

Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.

Severson TJ, Besur S, Bonkovsky HL.

World J Gastroenterol. 2016 Aug 7;22(29):6742-56. doi: 10.3748/wjg.v22.i29.6742. Review.

23.

Amoxicillin-Clavulanate-Induced Liver Injury.

deLemos AS, Ghabril M, Rockey DC, Gu J, Barnhart HX, Fontana RJ, Kleiner DE, Bonkovsky HL; Drug-Induced Liver Injury Network (DILIN).

Dig Dis Sci. 2016 Aug;61(8):2406-16. doi: 10.1007/s10620-016-4121-6. Epub 2016 Mar 22.

24.

Hepatotoxicity Associated with the Use of Anti-TNF-α Agents.

French JB, Bonacini M, Ghabril M, Foureau D, Bonkovsky HL.

Drug Saf. 2016 Mar;39(3):199-208. doi: 10.1007/s40264-015-0366-9. Review.

25.

Pitfalls in Erythrocyte Protoporphyrin Measurement for Diagnosis and Monitoring of Protoporphyrias.

Gou EW, Balwani M, Bissell DM, Bloomer JR, Bonkovsky HL, Desnick RJ, Naik H, Phillips JD, Singal AK, Wang B, Keel S, Anderson KE.

Clin Chem. 2015 Dec;61(12):1453-6. doi: 10.1373/clinchem.2015.245456. Epub 2015 Oct 19.

26.

Recent insights into the biological functions of liver fatty acid binding protein 1.

Wang G, Bonkovsky HL, de Lemos A, Burczynski FJ.

J Lipid Res. 2015 Dec;56(12):2238-47. doi: 10.1194/jlr.R056705. Epub 2015 Oct 6. Review.

27.

Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.

Vera T, D'Agostino RB Jr, Jordan JH, Whitlock MC, Meléndez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG.

Am J Cardiol. 2015 Dec 1;116(11):1752-5. doi: 10.1016/j.amjcard.2015.08.042. Epub 2015 Sep 10.

28.

Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.

Kline JA, Steuerwald NM, Watts JA, Courtney M, Bonkovsky HL.

Thromb Res. 2015 Oct;136(4):769-74. doi: 10.1016/j.thromres.2015.08.017. Epub 2015 Aug 28.

29.

Homeostasis of iron and hepcidin in erythropoietic protoporphyria.

Bossi K, Lee J, Schmeltzer P, Holburton E, Groseclose G, Besur S, Hwang S, Bonkovsky HL.

Eur J Clin Invest. 2015 Oct;45(10):1032-41. doi: 10.1111/eci.12503. Epub 2015 Sep 2.

PMID:
26199063
30.

Comparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance.

O'Brien TR, Pfeiffer RM, Paquin A, Lang Kuhs KA, Chen S, Bonkovsky HL, Edlin BR, Howell CD, Kirk GD, Kuniholm MH, Morgan TR, Strickler HD, Thomas DL, Prokunina-Olsson L.

J Hepatol. 2015 Nov;63(5):1103-10. doi: 10.1016/j.jhep.2015.06.035. Epub 2015 Jul 15.

31.

Acute Porphyrias.

Besur S, Schmeltzer P, Bonkovsky HL.

J Emerg Med. 2015 Sep;49(3):305-12. doi: 10.1016/j.jemermed.2015.04.034. Epub 2015 Jul 7. Review.

PMID:
26159905
32.

Afamelanotide for Erythropoietic Protoporphyria.

Langendonk JG, Balwani M, Anderson KE, Bonkovsky HL, Anstey AV, Bissell DM, Bloomer J, Edwards C, Neumann NJ, Parker C, Phillips JD, Lim HW, Hamzavi I, Deybach JC, Kauppinen R, Rhodes LE, Frank J, Murphy GM, Karstens FPJ, Sijbrands EJG, de Rooij FWM, Lebwohl M, Naik H, Goding CR, Wilson JHP, Desnick RJ.

N Engl J Med. 2015 Jul 2;373(1):48-59. doi: 10.1056/NEJMoa1411481.

33.

On stress and the liver: a chicken and egg conundrum.

Bonkovsky HL.

Gastroenterology. 2015 May;148(5):894-7. doi: 10.1053/j.gastro.2015.03.024. Epub 2015 Mar 21. No abstract available.

PMID:
25805419
34.

Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study.

Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J; United States Drug Induced Liver Injury Network.

Gastroenterology. 2015 Jun;148(7):1340-52.e7. doi: 10.1053/j.gastro.2015.03.006. Epub 2015 Mar 6.

35.

Herbal dietary supplement associated hepatotoxicity: an upcoming workshop and need for research.

Vuppalanchi R, Navarro V, Vega M, Bonkovsky HL, Seeff L, Serrano J; Drug-Induced Liver Injury Network (DILIN).

Gastroenterology. 2015 Mar;148(3):480-2. doi: 10.1053/j.gastro.2015.01.004. Epub 2015 Jan 8. No abstract available.

36.

Herbal products and the liver: a review of adverse effects and mechanisms.

Seeff LB, Bonkovsky HL, Navarro VJ, Wang G.

Gastroenterology. 2015 Mar;148(3):517-532.e3. doi: 10.1053/j.gastro.2014.12.004. Epub 2014 Dec 11. Review.

PMID:
25500423
37.

Comparative analysis of portal hepatic infiltrating leucocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis.

Foureau DM, Walling TL, Maddukuri V, Anderson W, Culbreath K, Kleiner DE, Ahrens WA, Jacobs C, Watkins PB, Fontana RJ, Chalasani N, Talwalkar J, Lee WM, Stolz A, Serrano J, Bonkovsky HL.

Clin Exp Immunol. 2015 Apr;180(1):40-51. doi: 10.1111/cei.12558.

38.

Clinically important features of porphyrin and heme metabolism and the porphyrias.

Besur S, Hou W, Schmeltzer P, Bonkovsky HL.

Metabolites. 2014 Nov 3;4(4):977-1006. doi: 10.3390/metabo4040977. Review.

39.

Hepatitis B and liver transplantation: molecular and clinical features that influence recurrence and outcome.

Ghaziani T, Sendi H, Shahraz S, Zamor P, Bonkovsky HL.

World J Gastroenterol. 2014 Oct 21;20(39):14142-55. doi: 10.3748/wjg.v20.i39.14142. Review.

40.

MiR-122 decreases HCV entry into hepatocytes through binding to the 3' UTR of OCLN mRNA.

Sendi H, Mehrab-Mohseni M, Foureau DM, Ghosh S, Walling TL, Steuerwald N, Zamor PJ, Kaplan KJ, Jacobs C, Ahrens WA, Russo MW, Clemens MG, Schrum LW, Bonkovsky HL.

Liver Int. 2015 Apr;35(4):1315-23. doi: 10.1111/liv.12698. Epub 2014 Oct 28.

PMID:
25302477
41.

Risk factors for severe or fatal drug-induced liver injury from amoxicillin-clavulanic acid.

Yazici C, Mutlu E, Bonkovsky HL, Russo MW.

Hepatol Res. 2015 Jun;45(6):676-82. doi: 10.1111/hepr.12410. Epub 2014 Oct 7.

PMID:
25163514
42.

Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network.

Navarro VJ, Barnhart H, Bonkovsky HL, Davern T, Fontana RJ, Grant L, Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R.

Hepatology. 2014 Oct;60(4):1399-408. doi: 10.1002/hep.27317. Epub 2014 Aug 25.

43.

Acute porphyrias in the USA: features of 108 subjects from porphyrias consortium.

Bonkovsky HL, Maddukuri VC, Yazici C, Anderson KE, Bissell DM, Bloomer JR, Phillips JD, Naik H, Peter I, Baillargeon G, Bossi K, Gandolfo L, Light C, Bishop D, Desnick RJ.

Am J Med. 2014 Dec;127(12):1233-41. doi: 10.1016/j.amjmed.2014.06.036. Epub 2014 Jul 10.

44.

ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury.

Chalasani NP, Hayashi PH, Bonkovsky HL, Navarro VJ, Lee WM, Fontana RJ; Practice Parameters Committee of the American College of Gastroenterology.

Am J Gastroenterol. 2014 Jul;109(7):950-66; quiz 967. doi: 10.1038/ajg.2014.131. Epub 2014 Jun 17.

PMID:
24935270
45.

Drug-induced liver injury with autoimmune features.

deLemos AS, Foureau DM, Jacobs C, Ahrens W, Russo MW, Bonkovsky HL.

Semin Liver Dis. 2014 May;34(2):194-204. doi: 10.1055/s-0034-1375959. Epub 2014 May 31. Review.

PMID:
24879983
46.

Indications for liver transplant and AASLD guidelines.

Thapar M, Bonkovsky HL.

Hepatology. 2015 Jan;61(1):408. doi: 10.1002/hep.27176. Epub 2014 Jun 26. No abstract available.

PMID:
24752818
47.

Statins and liver injury.

Thapar M, Russo MW, Bonkovsky HL.

Gastroenterol Hepatol (N Y). 2013 Sep;9(9):605-6. Review. No abstract available.

48.

Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network.

Russo MW, Hoofnagle JH, Gu J, Fontana RJ, Barnhart H, Kleiner DE, Chalasani N, Bonkovsky HL.

Hepatology. 2014 Aug;60(2):679-86. doi: 10.1002/hep.27157. Epub 2014 May 13.

49.

Hepatotoxicity of anti-TNF agents.

Bonacini M, Ghabril M, Bonkovsky HL.

Dig Dis Sci. 2014 May;59(5):1070-1. doi: 10.1007/s10620-014-3109-3. Epub 2014 Mar 21. No abstract available.

PMID:
24652111
50.

Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury.

Li T, Eheim AL, Klein S, Uschner FE, Smith AC, Brandon-Warner E, Ghosh S, Bonkovsky HL, Trebicka J, Schrum LW.

Hepatology. 2014 Jun;59(6):2383-96. doi: 10.1002/hep.27049. Epub 2014 Apr 29.

PMID:
24497272

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