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Items: 1 to 50 of 92

1.

Sevoflurane Promotes Bactericidal Properties of Macrophages through Enhanced Inducible Nitric Oxide Synthase Expression in Male Mice.

Gerber TJ, Fehr VCO, Oliveira SDS, Hu G, Dull R, Bonini MG, Beck-Schimmer B, Minshall RD.

Anesthesiology. 2019 Oct 24. doi: 10.1097/ALN.0000000000002992. [Epub ahead of print]

PMID:
31658116
2.

SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.

He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG.

Proc Natl Acad Sci U S A. 2019 Oct 7. pii: 201902308. doi: 10.1073/pnas.1902308116. [Epub ahead of print]

PMID:
31591207
3.

Depletion of Caveolin-1 in Type 2 Diabetes Model Induces Alzheimer's Disease Pathology Precursors.

Bonds JA, Shetti A, Bheri A, Chen Z, Disouky A, Tai L, Mao M, Head BP, Bonini MG, Haus JM, Minshall RD, Lazarov O.

J Neurosci. 2019 Oct 23;39(43):8576-8583. doi: 10.1523/JNEUROSCI.0730-19.2019. Epub 2019 Sep 16.

PMID:
31527120
4.

Cancer therapy-induced cardiovascular toxicity: old/new problems and old drugs.

Beyer AM, Bonini MG, Moslehi J.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H164-H167. doi: 10.1152/ajpheart.00277.2019. Epub 2019 Jun 7.

PMID:
31172808
5.

Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension.

Oliveira SDS, Chen J, Castellon M, Mao M, Raj JU, Comhair S, Erzurum S, Silva CLM, Machado RF, Bonini MG, Minshall RD.

Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1191-1202. doi: 10.1161/ATVBAHA.118.312038.

PMID:
30943774
6.

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.

Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR.

Nature. 2019 Apr;568(7751):254-258. doi: 10.1038/s41586-019-1005-x. Epub 2019 Mar 6.

7.

Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells.

Chen Z, D S Oliveira S, Zimnicka AM, Jiang Y, Sharma T, Chen S, Lazarov O, Bonini MG, Haus JM, Minshall RD.

Mol Biol Cell. 2018 May 15;29(10):1190-1202. doi: 10.1091/mbc.E17-01-0049. Epub 2018 Mar 22.

8.

Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.

Ganini D, Santos JH, Bonini MG, Mason RP.

Cell Chem Biol. 2018 Apr 19;25(4):413-425.e6. doi: 10.1016/j.chembiol.2018.01.007.

9.

Environmental Toxicant Exposures and Type 2 Diabetes Mellitus: Two Interrelated Public Health Problems on the Rise.

Bonini MG, Sargis RM.

Curr Opin Toxicol. 2018 Feb;7:52-59. doi: 10.1016/j.cotox.2017.09.003. Epub 2017 Oct 12.

10.

Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle.

Mey JT, Blackburn BK, Miranda ER, Chaves AB, Briller J, Bonini MG, Haus JM.

Am J Physiol Regul Integr Comp Physiol. 2018 Feb 1;314(2):R181-R190. doi: 10.1152/ajpregu.00159.2017. Epub 2017 Oct 18.

11.

Nitric oxide donor [Ru(terpy)(bdq)NO]3+ induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting oxidant production.

Potje SR, Chen Z, Oliveira SDS, Bendhack LM, da Silva RS, Bonini MG, Antoniali C, Minshall RD.

Free Radic Biol Med. 2017 Nov;112:587-596. doi: 10.1016/j.freeradbiomed.2017.09.004. Epub 2017 Sep 9.

12.

Mitochondria targeting by environmental stressors: Implications for redox cellular signaling.

Blajszczak C, Bonini MG.

Toxicology. 2017 Nov 1;391:84-89. doi: 10.1016/j.tox.2017.07.013. Epub 2017 Jul 24. Review.

13.

Manganese superoxide dismutase (SOD2): is there a center in the universe of mitochondrial redox signaling?

Zou X, Ratti BA, O'Brien JG, Lautenschlager SO, Gius DR, Bonini MG, Zhu Y.

J Bioenerg Biomembr. 2017 Aug;49(4):325-333. doi: 10.1007/s10863-017-9718-8. Epub 2017 Jun 14. Review.

PMID:
28616679
14.

Allele-specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-cadherin.

Ekoue DN, Bera S, Ansong E, Hart PC, Zaichick S, Domann FE, Bonini MG, Diamond AM.

Free Radic Res. 2017 Jun;51(6):582-590. doi: 10.1080/10715762.2017.1339303. Epub 2017 Jul 4.

15.

Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis.

Kenny TC, Hart P, Ragazzi M, Sersinghe M, Chipuk J, Sagar MAK, Eliceiri KW, LaFramboise T, Grandhi S, Santos J, Riar AK, Papa L, D'Aurello M, Manfredi G, Bonini MG, Germain D.

Oncogene. 2017 Aug;36(31):4393-4404. doi: 10.1038/onc.2017.52. Epub 2017 Apr 3.

16.

Racial disparity in survival from estrogen and progesterone receptor-positive breast cancer: implications for reducing breast cancer mortality disparities.

Rauscher GH, Silva A, Pauls H, Frasor J, Bonini MG, Hoskins K.

Breast Cancer Res Treat. 2017 Jun;163(2):321-330. doi: 10.1007/s10549-017-4166-z. Epub 2017 Mar 1.

17.

Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling.

Oliveira SDS, Castellon M, Chen J, Bonini MG, Gu X, Elliott MH, Machado RF, Minshall RD.

Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L760-L771. doi: 10.1152/ajplung.00484.2016. Epub 2017 Feb 10.

18.

Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis.

Ekoue DN, He C, Diamond AM, Bonini MG.

Biochim Biophys Acta Bioenerg. 2017 Aug;1858(8):628-632. doi: 10.1016/j.bbabio.2017.01.006. Epub 2017 Jan 11. Review.

19.

Selenium levels in human breast carcinoma tissue are associated with a common polymorphism in the gene for SELENOP (Selenoprotein P).

Ekoue DN, Zaichick S, Valyi-Nagy K, Picklo M, Lacher C, Hoskins K, Warso MA, Bonini MG, Diamond AM.

J Trace Elem Med Biol. 2017 Jan;39:227-233. doi: 10.1016/j.jtemb.2016.11.003. Epub 2016 Nov 11.

20.

Association of human papillomavirus, Neisseria gonorrhoeae and Chlamydia trachomatis co-infections on the risk of high-grade squamous intraepithelial cervical lesion.

de Abreu AL, Malaguti N, Souza RP, Uchimura NS, Ferreira ÉC, Pereira MW, Carvalho MD, Pelloso SM, Bonini MG, Gimenes F, Consolaro ME.

Am J Cancer Res. 2016 Jun 1;6(6):1371-83. eCollection 2016.

21.

SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions.

He C, Hart PC, Germain D, Bonini MG.

Trends Biochem Sci. 2016 Jul;41(7):568-577. doi: 10.1016/j.tibs.2016.04.004. Epub 2016 May 11.

22.

Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis.

Hart PC, Ratti BA, Mao M, Ansenberger-Fricano K, Shajahan-Haq AN, Tyner AL, Minshall RD, Bonini MG.

Oncotarget. 2016 Jan 5;7(1):308-22. doi: 10.18632/oncotarget.5687.

23.

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG.

J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31.

24.

Propofol increases morbidity and mortality in a rat model of sepsis.

Schläpfer M, Piegeler T, Dull RO, Schwartz DE, Mao M, Bonini MG, Z'Graggen BR, Beck-Schimmer B, Minshall RD.

Crit Care. 2015 Feb 19;19:45. doi: 10.1186/s13054-015-0751-x.

25.

MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.

Hart PC, Mao M, de Abreu AL, Ansenberger-Fricano K, Ekoue DN, Ganini D, Kajdacsy-Balla A, Diamond AM, Minshall RD, Consolaro ME, Santos JH, Bonini MG.

Nat Commun. 2015 Feb 5;6:6053. doi: 10.1038/ncomms7053.

26.

Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: a candidate molecule for therapeutic intervention and prognostic biomarker?

Gimenes F, Teixeira JJ, de Abreu AL, Souza RP, Pereira MW, da Silva VR, Bôer CG, Maria-Engler SS, Bonini MG, Borelli SD, Consolaro ME.

Biochim Biophys Acta. 2014 Dec;1846(2):576-89. doi: 10.1016/j.bbcan.2014.10.004. Epub 2014 Oct 23. Review.

PMID:
25453366
27.

Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.

Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L208-20. doi: 10.1152/ajplung.00242.2014. Epub 2014 Nov 21.

28.

Redox regulation of NF-κB p50 and M1 polarization in microglia.

Taetzsch T, Levesque S, McGraw C, Brookins S, Luqa R, Bonini MG, Mason RP, Oh U, Block ML.

Glia. 2015 Mar;63(3):423-40. doi: 10.1002/glia.22762. Epub 2014 Oct 21.

29.

Male infertility: a public health issue caused by sexually transmitted pathogens.

Gimenes F, Souza RP, Bento JC, Teixeira JJ, Maria-Engler SS, Bonini MG, Consolaro ME.

Nat Rev Urol. 2014 Dec;11(12):672-87. doi: 10.1038/nrurol.2014.285. Epub 2014 Oct 21. Review.

PMID:
25330794
30.

Nitroglycerin tolerance in caveolin-1 deficient mice.

Mao M, Varadarajan S, Fukai T, Bakhshi FR, Chernaya O, Dudley SC Jr, Minshall RD, Bonini MG.

PLoS One. 2014 Aug 26;9(8):e104101. doi: 10.1371/journal.pone.0104101. eCollection 2014.

31.

Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.

Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM.

Cancer Res. 2014 Sep 15;74(18):5118-26. doi: 10.1158/0008-5472.CAN-14-0660. Epub 2014 Jul 21.

32.

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase.

Yang KC, Rutledge CA, Mao M, Bakhshi FR, Xie A, Liu H, Bonini MG, Patel HH, Minshall RD, Dudley SC Jr.

Circ Arrhythm Electrophysiol. 2014 Aug;7(4):701-10. doi: 10.1161/CIRCEP.113.001394. Epub 2014 Jul 13.

33.

Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension.

Bakhshi FR, Mao M, Shajahan AN, Piegeler T, Chen Z, Chernaya O, Sharma T, Elliott WM, Szulcek R, Bogaard HJ, Comhair S, Erzurum S, van Nieuw Amerongen GP, Bonini MG, Minshall RD.

Pulm Circ. 2013 Dec;3(4):816-30. doi: 10.1086/674753.

34.

Sensitive simultaneous detection of seven sexually transmitted agents in semen by multiplex-PCR and of HPV by single PCR.

Gimenes F, Medina FS, Abreu AL, Irie MM, Esquiçati IB, Malagutti N, Vasconcellos VR, Discacciati MG, Bonini MG, Maria-Engler SS, Consolaro ME.

PLoS One. 2014 Jun 12;9(6):e98862. doi: 10.1371/journal.pone.0098862. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e112864.

35.

Regulating the regulator of ROS production.

Bonini MG, Malik AB.

Cell Res. 2014 Aug;24(8):908-9. doi: 10.1038/cr.2014.66. Epub 2014 May 20.

36.

Mitochondria and arrhythmias.

Yang KC, Bonini MG, Dudley SC Jr.

Free Radic Biol Med. 2014 Jun;71:351-61. doi: 10.1016/j.freeradbiomed.2014.03.033. Epub 2014 Apr 5. Review.

37.

Redox control of enzymatic functions: The electronics of life's circuitry.

Bonini MG, Consolaro MEL, Hart PC, Mao M, de Abreu ALP, Master AM.

IUBMB Life. 2014 Mar;66(3):167-181. doi: 10.1002/iub.1258. Epub 2014 Mar 26. Review.

38.

Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin.

Gong H, Gao X, Feng S, Siddiqui MR, Garcia A, Bonini MG, Komarova Y, Vogel SM, Mehta D, Malik AB.

J Exp Med. 2014 Mar 10;211(3):579-91. doi: 10.1084/jem.20131190. Epub 2014 Mar 3.

39.

Endothelial barrier protection by local anesthetics: ropivacaine and lidocaine block tumor necrosis factor-α-induced endothelial cell Src activation.

Piegeler T, Votta-Velis EG, Bakhshi FR, Mao M, Carnegie G, Bonini MG, Schwartz DE, Borgeat A, Beck-Schimmer B, Minshall RD.

Anesthesiology. 2014 Jun;120(6):1414-28. doi: 10.1097/ALN.0000000000000174.

40.

Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis.

Hecquet CM, Zhang M, Mittal M, Vogel SM, Di A, Gao X, Bonini MG, Malik AB.

Circ Res. 2014 Jan 31;114(3):469-79. doi: 10.1161/CIRCRESAHA.114.302414. Epub 2013 Dec 11.

41.

The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all?

Bonini MG, Gantner BN.

IUBMB Life. 2013 Nov;65(11):889-96. doi: 10.1002/iub.1213. Review.

42.

Differences in the mutation of the p53 gene in exons 6 and 7 in cervical samples from HIV- and HPV-infected women.

Souza RP, Gimenes F, de Abreu AL, Rocha-Brischiliari SC, de Carvalho MD, Ferreira EC, Bonini MG, Pelloso SM, Consolaro ME.

Infect Agent Cancer. 2013 Oct 7;8(1):38. doi: 10.1186/1750-9378-8-38.

43.

Simultaneous detection of seven sexually transmitted agents in human immunodeficiency virus-infected Brazilian women by multiplex polymerase chain reaction.

Souza RP, de Abreu AL, Ferreira ÉC, Rocha-Brischiliari SC, de B Carvalho MD, Pelloso SM, Bonini MG, Gimenes F, Consolaro ME.

Am J Trop Med Hyg. 2013 Dec;89(6):1199-202. doi: 10.4269/ajtmh.13-0315. Epub 2013 Sep 30.

44.

Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.

Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D.

Am J Physiol Lung Cell Mol Physiol. 2013 Aug 15;305(4):L291-300. doi: 10.1152/ajplung.00094.2013. Epub 2013 Jun 14.

45.

In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis.

Towner RA, Smith N, Saunders D, Lupu F, Silasi-Mansat R, West M, Ramirez DC, Gomez-Mejiba SE, Bonini MG, Mason RP, Ehrenshaft M, Hensley K.

Free Radic Biol Med. 2013 Oct;63:351-60. doi: 10.1016/j.freeradbiomed.2013.05.026. Epub 2013 May 28.

PMID:
23722162
46.

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.

Dallas S, Block ML, Thompson DM, Bonini MG, Ronaldson PT, Bendayan R, Miller DS.

J Neuroinflammation. 2013 May 4;10:58. doi: 10.1186/1742-2094-10-58.

47.

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death.

Sovari AA, Rutledge CA, Jeong EM, Dolmatova E, Arasu D, Liu H, Vahdani N, Gu L, Zandieh S, Xiao L, Bonini MG, Duffy HS, Dudley SC Jr.

Circ Arrhythm Electrophysiol. 2013 Jun;6(3):623-31. doi: 10.1161/CIRCEP.112.976787. Epub 2013 Apr 4.

48.

Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin.

Sieracki NA, Gantner BN, Mao M, Horner JH, Ye RD, Malik AB, Newcomb ME, Bonini MG.

Free Radic Biol Med. 2013 Aug;61:40-50. doi: 10.1016/j.freeradbiomed.2013.02.020. Epub 2013 Mar 7.

49.

Two hypotheses for the oxidation of SOD1-Cu(I).

Mason RP, Ganini D, Bonini MG, Ranguelova K.

Free Radic Biol Med. 2012 Nov 15;53(10):1991-2. doi: 10.1016/j.freeradbiomed.2012.10.524. No abstract available.

PMID:
23137624
50.

Glutathiolated Ras: characterization and implications for Ras activation.

Hobbs GA, Bonini MG, Gunawardena HP, Chen X, Campbell SL.

Free Radic Biol Med. 2013 Apr;57:221-9. doi: 10.1016/j.freeradbiomed.2012.10.531. Epub 2012 Oct 30.

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