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Items: 1 to 50 of 315

1.

Novel minor HLA DR associated antigens in type 1 diabetes.

Müller D, Telieps T, Eugster A, Weinzierl C, Jolink M, Ziegler AG, Bonifacio E.

Clin Immunol. 2018 Jul 7;194:87-91. doi: 10.1016/j.clim.2018.07.001. [Epub ahead of print]

2.

Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing.

Hippich M, Oleynik A, Jain K, Winkler C, Ferreira RC, Bonifacio E, Ziegler AG, Briese T.

Acta Diabetol. 2018 Aug;55(8):881-884. doi: 10.1007/s00592-018-1138-7. Epub 2018 Apr 23. No abstract available.

PMID:
29687279
3.

Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.

Achenbach P, Hawa MI, Krause S, Lampasona V, Jerram ST, Williams AJK, Bonifacio E, Ziegler AG, Leslie RD; Action LADA consortium.

Diabetologia. 2018 Jul;61(7):1644-1649. doi: 10.1007/s00125-018-4605-3. Epub 2018 Apr 4.

PMID:
29619531
4.

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.

Bonifacio E, Beyerlein A, Hippich M, Winkler C, Vehik K, Weedon MN, Laimighofer M, Hattersley AT, Krumsiek J, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Oram RA, Rich SS, Ziegler AG; TEDDY Study Group.

PLoS Med. 2018 Apr 3;15(4):e1002548. doi: 10.1371/journal.pmed.1002548. eCollection 2018 Apr.

5.

A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.

Mehdi AM, Hamilton-Williams EE, Cristino A, Ziegler A, Bonifacio E, Le Cao KA, Harris M, Thomas R.

JCI Insight. 2018 Mar 8;3(5). pii: 98212. doi: 10.1172/jci.insight.98212. [Epub ahead of print]

6.

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.

Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group, Carel JC, Tubiana-Rufi N, Martinerie L, Poidvin A, JacqzAigrain E, Corvez L, Berruer V, Gautier JF, Baz B, Haddadi N, Andreelli F, Amouyal C, Jaqueminet S, Bourron O, Dasque E, Hartemann A, Lemoine-Yazigi A, Dubois-Laforgue D, Travert F, Feron M, Rolland P, Vignali V, Marre M, Chanson P, Briet C, Guillausseau PJ, Ait-Bachir L, Collet C, Beziaud F, Desforges-Bullet V, Petit-Aubert G, Christin-Maitre S, Fève B, Vatier C, Bourcigaux N, Lautridou C, Lahlou N, Bakouboula P, Elie C, Morel H, Treluyer JM, Gagnerault MC, Maillard C, Jones A.

Sci Immunol. 2018 Feb 2;3(20). pii: eaao4013. doi: 10.1126/sciimmunol.aao4013.

PMID:
29429978
7.

GM-CSF producing autoreactive CD4+ T cells in type 1 diabetes.

Knoop J, Gavrisan A, Kuehn D, Reinhardt J, Heinrich M, Hippich M, Eugster A, Ockert C, Ziegler AG, Bonifacio E.

Clin Immunol. 2018 Mar;188:23-30. doi: 10.1016/j.clim.2017.12.002. Epub 2017 Dec 8.

8.

Allele-specific methylation of type 1 diabetes susceptibility genes.

Kindt ASD, Fuerst RW, Knoop J, Laimighofer M, Telieps T, Hippich M, Woerheide MA, Wahl S, Wilson R, Sedlmeier EM, Hommel A, Todd JA, Krumsiek J, Ziegler AG, Bonifacio E.

J Autoimmun. 2018 May;89:63-74. doi: 10.1016/j.jaut.2017.11.008. Epub 2017 Dec 8.

9.

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.

Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P.

Diabetologia. 2018 Mar;61(3):641-657. doi: 10.1007/s00125-017-4500-3. Epub 2017 Nov 28.

10.

Thymus Growth and Fetal Immune Responses in Diabetic Pregnancies.

Warncke K, Lickert R, Eitel S, Gloning KP, Bonifacio E, Sedlmeier EM, Becker P, Knoop J, Beyerlein A, Ziegler AG.

Horm Metab Res. 2017 Nov;49(11):892-898. doi: 10.1055/s-0043-120671. Epub 2017 Nov 14.

PMID:
29136677
11.

Screening for Type 1 Diabetes Risk in Newborns: The Freder1k Pilot Study in Saxony.

Hommel A, Haupt F, Delivani P, Winkler C, Stopsack M, Wimberger P, Nitzsche K, Heinke S, Naeke A, Ceglarek U, Thiery J, Bergert R, Stadthaus D, Groeger K, Heubner G, Schramm U, Dziambor U, Zirkel A, Kiess W, Mueller I, Lange K, Berner R, Bonifacio E, Ziegler AG; and the Freder1k Study Group.

Horm Metab Res. 2018 Jan;50(1):44-49. doi: 10.1055/s-0043-120921. Epub 2017 Nov 9.

PMID:
29121687
12.

Gian Franco Bottazzo, 1946-2017.

Bonifacio E, Bosi E, Leslie RD.

Diabetologia. 2018 Jan;61(1):3-5. doi: 10.1007/s00125-017-4486-x. No abstract available.

PMID:
29085989
13.

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes.

Ludwig B, Ludwig S, Steffen A, Knauf Y, Zimerman B, Heinke S, Lehmann S, Schubert U, Schmid J, Bleyer M, Schönmann U, Colton CK, Bonifacio E, Solimena M, Reichel A, Schally AV, Rotem A, Barkai U, Grinberg-Rashi H, Kaup FJ, Avni Y, Jones P, Bornstein SR.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11745-11750. doi: 10.1073/pnas.1708420114. Epub 2017 Oct 16.

14.

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies.

Lynch KF, Lee HS, Törn C, Vehik K, Krischer JP, Larsson HE, Haller MJ, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Hyöty H, Bonifacio E, Lernmark Å; TEDDY Study Group.

J Autoimmun. 2018 Jan;86:93-103. doi: 10.1016/j.jaut.2017.09.005. Epub 2017 Sep 21.

PMID:
28941965
15.

Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.

Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M.

Cell Metab. 2017 Sep 5;26(3):568-575.e3. doi: 10.1016/j.cmet.2017.08.013.

PMID:
28877460
16.

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells.

Bandoła J, Richter C, Ryser M, Jamal A, Ashton MP, von Bonin M, Kuhn M, Dorschner B, Alexopoulou D, Navratiel K, Roeder I, Dahl A, Hedrich CM, Bonifacio E, Brenner S, Thieme S.

Front Immunol. 2017 Aug 17;8:981. doi: 10.3389/fimmu.2017.00981. eCollection 2017.

17.

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study.

Köhler M, Beyerlein A, Vehik K, Greven S, Umlauf N, Lernmark Å, Hagopian WA, Rewers M, She JX, Toppari J, Akolkar B, Krischer JP, Bonifacio E, Ziegler AG; TEDDY study group.

Acta Diabetol. 2017 Nov;54(11):1009-1017. doi: 10.1007/s00592-017-1033-7. Epub 2017 Aug 30.

PMID:
28856522
18.

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells.

Heidenreich F, Rücker-Braun E, Walz JS, Eugster A, Kühn D, Dietz S, Nelde A, Tunger A, Wehner R, Link CS, Middeke JM, Stölzel F, Tonn T, Stevanovic S, Rammensee HG, Bonifacio E, Bachmann M, Zeis M, Ehninger G, Bornhäuser M, Schetelig J, Schmitz M.

Haematologica. 2017 Nov;102(11):e460-e464. doi: 10.3324/haematol.2017.167312. Epub 2017 Aug 24. No abstract available.

19.

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

van den Bruck R, Weil PP, Ziegenhals T, Schreiner P, Juranek S, Gödde D, Vogel S, Schuster F, Orth V, Dörner J, Pembaur D, Röper M, Störkel S, Zirngibl H, Wirth S, Jenke ACW, Postberg J, Boy N, Heringer J, Haege G, Glahn EM, Hoffmann GF, Garbade SF, Burgard P, Kölker S, Chao CM, Yahya F, Moiseenko A, Shrestha A, Ahmadvand N, Quantius J, Wilhelm J, El-Agha E, Zimmer KP, Bellusci S, Staufner C, Kölker S, Prokisch H, Hoffmann GF, Seeliger S, Müller M, Hippe A, Steinkraus H, Wauer R, Lachmann B, Hofmann SR, Hedrich CM, Zierk J, Arzideh F, Haeckel R, Rascher W, Rauh M, Metzler M, Thieme S, Bandoła J, Richter C, Ryser M, Jamal A, Ashton MP, von Bonin M, Kuhn M, Hedrich CM, Bonifacio E, Berner R, Brenner S, Hammersen J, Has C, Naumann-Bartsch N, Stachel D, Kiritsi D, Söder S, Tardieu M, Metzler M, Bruckner-Tuderman L, Schneider H, Bohne F, Langer D, Cencic R, Eggermann T, Zechner U, Pelletier J, Zepp F, Enklaar T, Prawitt D, Pech M, Weckmann M, Heinsen FA, Franke A, Happle C, Dittrich AM, Hansen G, Fuchs O, von Mutius E, Oliver BG, Kopp MV, Paret C, Russo A, Theruvath J, Keller B, El Malki K, Lehmann N, Wingerter A, Neu MA, Aslihan GA, Wagner W, Sommer C, Pietsch T, Seidmann L, Faber J, Schreiner F, Ackermann M, Michalik M, Rother E, Bilkei-Gorzo A, Racz I, Bindila L, Lutz B, Dötsch J, Zimmer A, Woelfle J, Fischer HS, Ullrich TL, Bührer C, Czernik C, Schmalisch G, Stein R, Hofmann SR, Hagenbuchner J, Kiechl-Kohlendorfer U, Obexer P, Ausserlechner MJ, Loges NT, Frommer AT, Wallmeier J, Omran H, Öner-Sieben S, Gimpfl M, Rozman J, Irmler M, Beckers J, De Angelis MH, Roscher A, Wolf E, Ensenauer R, Nemes K, Frühwald M, Hasselblatt M, Siebert R, Kordes U, Kool M, Wang H, Hardy H, Refai O, Barwick KES, Zimmerman HH, Weis J, Baple EL, Crosby AH, Cirak S, Hellmuth C, Uhl O, Standl M, Heinrich J, Thiering E, Koletzko B, Blümel L, Kerl K, Picard D, Frühwald MC, Liebau MC, Reifenberger G, Borkhardt A, Hasselblatt M, Remke M, Tews D, Wabitsch M, Fischer-Posovszky P, Westhoff MA, Nonnenmacher L, Langhans J, Schneele L, Trenkler N, Debatin KM.

Mol Cell Pediatr. 2017 May;4(Suppl 1):5. doi: 10.1186/s40348-017-0071-0. No abstract available.

20.

Type 1 diabetes mellitus.

Katsarou A, Gudbjörnsdottir S, Rawshani A, Dabelea D, Bonifacio E, Anderson BJ, Jacobsen LM, Schatz DA, Lernmark Å.

Nat Rev Dis Primers. 2017 Mar 30;3:17016. doi: 10.1038/nrdp.2017.16. Review.

PMID:
28358037
21.

CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.

Fuchs YF, Eugster A, Dietz S, Sebelefsky C, Kühn D, Wilhelm C, Lindner A, Gavrisan A, Knoop J, Dahl A, Ziegler AG, Bonifacio E.

Sci Rep. 2017 Mar 16;7:44661. doi: 10.1038/srep44661.

22.

Assessment of the T cell receptor repertoire in long-term platelet donors by next generation sequencing.

Link CS, Hölig K, Rücker-Braun E, Lang K, Kuhn M, Eugster A, Klesse C, Schmiedgen M, Heidenreich F, Oelschlägel U, Dahl A, Bornhäuser M, Bonifacio E, Schetelig J.

Br J Haematol. 2018 May;181(3):389-391. doi: 10.1111/bjh.14576. Epub 2017 Mar 8. No abstract available.

PMID:
28272738
23.

A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.

Heninger AK, Eugster A, Kuehn D, Buettner F, Kuhn M, Lindner A, Dietz S, Jergens S, Wilhelm C, Beyerlein A, Ziegler AG, Bonifacio E.

Sci Transl Med. 2017 Feb 22;9(378). pii: eaaf8848. doi: 10.1126/scitranslmed.aaf8848.

PMID:
28228602
24.

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.

Cerdá-Esteban N, Naumann H, Ruzittu S, Mah N, Pongrac IM, Cozzitorto C, Hommel A, Andrade-Navarro MA, Bonifacio E, Spagnoli FM.

Nat Commun. 2017 Feb 13;8:14127. doi: 10.1038/ncomms14127.

25.

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.

Skyler JS, Bakris GL, Bonifacio E, Darsow T, Eckel RH, Groop L, Groop PH, Handelsman Y, Insel RA, Mathieu C, McElvaine AT, Palmer JP, Pugliese A, Schatz DA, Sosenko JM, Wilding JP, Ratner RE.

Diabetes. 2017 Feb;66(2):241-255. doi: 10.2337/db16-0806. Epub 2016 Dec 15. Review.

26.

Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.

Ziegler AG, Bonifacio E, Powers AC, Todd JA, Harrison LC, Atkinson MA.

Diabetes. 2016 Nov;65(11):3233-3239.

27.

Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.

Tunger A, Wehner R, von Bonin M, Kühn D, Heidenreich F, Matko S, Nauerth M, Rücker-Braun E, Dietz S, Link CS, Eugster A, Odendahl M, Busch DH, Tonn T, Bonifacio E, Germeroth L, Schetelig J, Bachmann MP, Bornhäuser M, Schmitz M.

Leuk Lymphoma. 2017 May;58(5):1246-1249. doi: 10.1080/10428194.2016.1233538. Epub 2016 Nov 16. No abstract available.

PMID:
27852136
28.

Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity.

Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA.

Diabetologia. 2017 Jan;60(1):35-38. Epub 2016 Oct 26.

29.

T cell receptor repertoires after adoptive transfer of expanded allogeneic regulatory T cells.

Theil A, Wilhelm C, Kuhn M, Petzold A, Tuve S, Oelschlägel U, Dahl A, Bornhäuser M, Bonifacio E, Eugster A.

Clin Exp Immunol. 2017 Feb;187(2):316-324. doi: 10.1111/cei.12887. Epub 2016 Nov 27.

30.

Sources of errors and uncertainties in the assessment of forest soil carbon stocks at different scales-review and recommendations.

Vanguelova EI, Bonifacio E, De Vos B, Hoosbeek MR, Berger TW, Vesterdal L, Armolaitis K, Celi L, Dinca L, Kjønaas OJ, Pavlenda P, Pumpanen J, Püttsepp Ü, Reidy B, Simončič P, Tobin B, Zhiyanski M.

Environ Monit Assess. 2016 Nov;188(11):630. Epub 2016 Oct 21. Review.

PMID:
27770347
31.

3 Screen islet cell autoantibody ELISA: A sensitive and specific ELISA for the combined measurement of autoantibodies to GAD65, to IA-2 and to ZnT8.

Amoroso M, Achenbach P, Powell M, Coles R, Chlebowska M, Carr L, Furmaniak J, Scholz M, Bonifacio E, Ziegler AG, Rees Smith B.

Clin Chim Acta. 2016 Nov 1;462:60-64. doi: 10.1016/j.cca.2016.08.013. Epub 2016 Aug 26.

PMID:
27570064
32.

Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin.

Ashton MP, Eugster A, Walther D, Daehling N, Riethausen S, Kuehn D, Klingel K, Beyerlein A, Zillmer S, Ziegler AG, Bonifacio E.

Sci Rep. 2016 Sep 8;6:32899. doi: 10.1038/srep32899.

33.

3 Screen ELISA for High-Throughput Detection of Beta Cell Autoantibodies in Capillary Blood.

Ziegler AG, Haupt F, Scholz M, Weininger K, Wittich S, Löbner S, Matzke C, Gezginci C, Riethausen S, Beyerlein A, Zillmer S, Amoroso M, Coles R, Powell M, Furmaniak J, Smith BR, Winkler C, Bonifacio E, Achenbach P.

Diabetes Technol Ther. 2016 Nov;18(11):687-693. Epub 2016 Aug 23.

PMID:
27552135
34.

Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells.

Borg DJ, Welzel PB, Grimmer M, Friedrichs J, Weigelt M, Wilhelm C, Prewitz M, Stißel A, Hommel A, Kurth T, Freudenberg U, Bonifacio E, Werner C.

Acta Biomater. 2016 Oct 15;44:178-87. doi: 10.1016/j.actbio.2016.08.007. Epub 2016 Aug 6.

PMID:
27506126
35.

A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.

Endesfelder D, Hagen M, Winkler C, Haupt F, Zillmer S, Knopff A, Bonifacio E, Ziegler AG, Zu Castell W, Achenbach P.

Diabetologia. 2016 Oct;59(10):2172-80. doi: 10.1007/s00125-016-4050-0. Epub 2016 Jul 11.

PMID:
27400691
36.

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.

Vehik K, Lynch KF, Schatz DA, Akolkar B, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Lernmark Å, Bonifacio E, Krischer JP; TEDDY Study Group.

Diabetes Care. 2016 Sep;39(9):1535-42. doi: 10.2337/dc16-0181. Epub 2016 Jun 16.

37.

Tetraspanin 7 autoantibodies in type 1 diabetes.

Walther D, Eugster A, Jergens S, Gavrisan A, Weinzierl C, Telieps T, Winkler C, Ziegler AG, Bonifacio E.

Diabetologia. 2016 Sep;59(9):1973-6. doi: 10.1007/s00125-016-3997-1. Epub 2016 May 25.

PMID:
27221092
38.

Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study.

Raab J, Haupt F, Scholz M, Matzke C, Warncke K, Lange K, Assfalg R, Weininger K, Wittich S, Löbner S, Beyerlein A, Nennstiel-Ratzel U, Lang M, Laub O, Dunstheimer D, Bonifacio E, Achenbach P, Winkler C, Ziegler AG; Fr1da Study Group.

BMJ Open. 2016 May 18;6(5):e011144. doi: 10.1136/bmjopen-2016-011144.

39.

Primary prevention of beta-cell autoimmunity and type 1 diabetes - The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.

Ziegler AG, Danne T, Dunger DB, Berner R, Puff R, Kiess W, Agiostratidou G, Todd JA, Bonifacio E.

Mol Metab. 2016 Feb 22;5(4):255-262. doi: 10.1016/j.molmet.2016.02.003. eCollection 2016 Apr. Review.

40.

Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the disease.

Wasserfall C, Montgomery E, Yu L, Michels A, Gianani R, Pugliese A, Nierras C, Kaddis JS, Schatz DA, Bonifacio E, Atkinson MA.

Clin Exp Immunol. 2016 Jul;185(1):33-41. doi: 10.1111/cei.12797. Epub 2016 May 4.

41.

Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice.

Telieps T, Köhler M, Treise I, Foertsch K, Adler T, Busch DH, Hrabě de Angelis M, Verschoor A, Adler K, Bonifacio E, Ziegler AG.

J Diabetes Res. 2016;2016:4208156. doi: 10.1155/2016/4208156. Epub 2016 Feb 4.

42.

Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8(+) T cell receptor alpha repertoire following allogeneic transplantation.

Link CS, Eugster A, Heidenreich F, Rücker-Braun E, Schmiedgen M, Oelschlägel U, Kühn D, Dietz S, Fuchs Y, Dahl A, Domingues AM, Klesse C, Schmitz M, Ehninger G, Bornhäuser M, Schetelig J, Bonifacio E.

Clin Exp Immunol. 2016 Jun;184(3):389-402. doi: 10.1111/cei.12770. Epub 2016 Mar 8.

43.

Isolation of human monoclonal autoantibodies derived from pancreatic lymph node and peripheral blood B cells of islet autoantibody-positive patients.

Catani M, Walther D, Christie MR, McLaughlin KA, Bonifacio E, Eugster A.

Diabetologia. 2016 Feb;59(2):294-8.

PMID:
26493188
44.

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.

Giannopoulou EZ, Winkler C, Chmiel R, Matzke C, Scholz M, Beyerlein A, Achenbach P, Bonifacio E, Ziegler AG.

Diabetologia. 2015 Oct;58(10):2317-23. doi: 10.1007/s00125-015-3672-y. Epub 2015 Jul 3.

PMID:
26138334
45.

Compromised immune response in infants at risk for type 1 diabetes born by Caesarean Section.

Puff R, D'Orlando O, Heninger AK, Kühn D, Krause S, Winkler C, Beyerlein A, Bonifacio E, Ziegler AG.

Clin Immunol. 2015 Oct;160(2):282-5. doi: 10.1016/j.clim.2015.06.008. Epub 2015 Jun 23.

PMID:
26111479
46.

Relationships between major epitopes of the IA-2 autoantigen in Type 1 diabetes: Implications for determinant spreading.

McLaughlin KA, Richardson CC, Williams S, Bonifacio E, Morgan D, Feltbower RG, Powell M, Rees Smith B, Furmaniak J, Christie MR.

Clin Immunol. 2015 Oct;160(2):226-36. doi: 10.1016/j.clim.2015.06.002. Epub 2015 Jun 9.

47.

Predicting type 1 diabetes using biomarkers.

Bonifacio E.

Diabetes Care. 2015 Jun;38(6):989-96. doi: 10.2337/dc15-0101.

PMID:
25998291
48.

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Dopico XC, Evangelou M, Ferreira RC, Guo H, Pekalski ML, Smyth DJ, Cooper N, Burren OS, Fulford AJ, Hennig BJ, Prentice AM, Ziegler AG, Bonifacio E, Wallace C, Todd JA.

Nat Commun. 2015 May 12;6:7000. doi: 10.1038/ncomms8000.

49.

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.

Bonifacio E, Ziegler AG, Klingensmith G, Schober E, Bingley PJ, Rottenkolber M, Theil A, Eugster A, Puff R, Peplow C, Buettner F, Lange K, Hasford J, Achenbach P; Pre-POINT Study Group.

JAMA. 2015 Apr 21;313(15):1541-9. doi: 10.1001/jama.2015.2928.

PMID:
25898052
50.

Vagaries of the ELISpot assay: specific detection of antigen responsive cells requires purified CD8(+) T cells and MHC class I expressing antigen presenting cell lines.

Fuchs YF, Jainta GW, Kühn D, Wilhelm C, Weigelt M, Karasinsky A, Upadhyaya B, Ziegler AG, Bonifacio E.

Clin Immunol. 2015 Apr;157(2):216-25. doi: 10.1016/j.clim.2015.02.012. Epub 2015 Feb 27.

PMID:
25728493

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