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Items: 1 to 50 of 259

1.

The autophagy protein ATG9A promotes HIV-1 infectivity.

Mailler E, Waheed AA, Park SY, Gershlick DC, Freed EO, Bonifacino JS.

Retrovirology. 2019 Jul 3;16(1):18. doi: 10.1186/s12977-019-0480-3.

2.

Lysosome Positioning Influences mTORC2 and AKT Signaling.

Jia R, Bonifacino JS.

Mol Cell. 2019 Jul 11;75(1):26-38.e3. doi: 10.1016/j.molcel.2019.05.009. Epub 2019 May 23.

PMID:
31130364
3.

Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning.

Guardia CM, De Pace R, Sen A, Saric A, Jarnik M, Kolin DA, Kunwar A, Bonifacino JS.

PLoS Biol. 2019 May 17;17(5):e3000279. doi: 10.1371/journal.pbio.3000279. eCollection 2019 May.

4.

A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.

Sharma G, Guardia CM, Roy A, Vassilev A, Saric A, Griner LN, Marugan J, Ferrer M, Bonifacino JS, DePamphilis ML.

Autophagy. 2019 Feb 26:1-25. doi: 10.1080/15548627.2019.1586257. [Epub ahead of print]

PMID:
30806145
5.

A neurodevelopmental disorder caused by mutations in the VPS51 subunit of the GARP and EARP complexes.

Gershlick DC, Ishida M, Jones JR, Bellomo A, Bonifacino JS, Everman DB.

Hum Mol Genet. 2019 May 1;28(9):1548-1560. doi: 10.1093/hmg/ddy423.

PMID:
30624672
6.

Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome.

De Pace R, Skirzewski M, Damme M, Mattera R, Mercurio J, Foster AM, Cuitino L, Jarnik M, Hoffmann V, Morris HD, Han TU, Mancini GMS, Buonanno A, Bonifacino JS.

PLoS Genet. 2018 Apr 26;14(4):e1007363. doi: 10.1371/journal.pgen.1007363. eCollection 2018 Apr.

7.

Neuronal functions of adaptor complexes involved in protein sorting.

Guardia CM, De Pace R, Mattera R, Bonifacino JS.

Curr Opin Neurobiol. 2018 Aug;51:103-110. doi: 10.1016/j.conb.2018.02.021. Epub 2018 Mar 17. Review.

PMID:
29558740
8.

Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.

Romano-Moreno M, Rojas AL, Williamson CD, Gershlick DC, Lucas M, Isupov MN, Bonifacino JS, Machner MP, Hierro A.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11151-E11160. doi: 10.1073/pnas.1715361115. Epub 2017 Dec 11.

9.

AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation.

Mattera R, Park SY, De Pace R, Guardia CM, Bonifacino JS.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10697-E10706. doi: 10.1073/pnas.1717327114. Epub 2017 Nov 27.

10.

A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability.

Pu J, Keren-Kaplan T, Bonifacino JS.

J Cell Biol. 2017 Dec 4;216(12):4183-4197. doi: 10.1083/jcb.201703094. Epub 2017 Oct 9.

11.

Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers.

Chen Y, Gershlick DC, Park SY, Bonifacino JS.

J Cell Biol. 2017 Dec 4;216(12):4141-4151. doi: 10.1083/jcb.201707172. Epub 2017 Oct 4.

12.

BORC coordinates encounter and fusion of lysosomes with autophagosomes.

Jia R, Guardia CM, Pu J, Chen Y, Bonifacino JS.

Autophagy. 2017 Oct 3;13(10):1648-1663. doi: 10.1080/15548627.2017.1343768. Epub 2017 Aug 21.

13.

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon.

Farías GG, Guardia CM, De Pace R, Britt DJ, Bonifacino JS.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2955-E2964. doi: 10.1073/pnas.1616363114. Epub 2017 Mar 20.

14.

Moving and positioning the endolysosomal system.

Bonifacino JS, Neefjes J.

Curr Opin Cell Biol. 2017 Aug;47:1-8. doi: 10.1016/j.ceb.2017.01.008. Epub 2017 Feb 21. Review.

15.

Structural Mechanism for Cargo Recognition by the Retromer Complex.

Lucas M, Gershlick DC, Vidaurrazaga A, Rojas AL, Bonifacino JS, Hierro A.

Cell. 2016 Dec 1;167(6):1623-1635.e14. doi: 10.1016/j.cell.2016.10.056. Epub 2016 Nov 23.

16.

BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.

Guardia CM, Farías GG, Jia R, Pu J, Bonifacino JS.

Cell Rep. 2016 Nov 15;17(8):1950-1961. doi: 10.1016/j.celrep.2016.10.062.

17.

Mechanisms and functions of lysosome positioning.

Pu J, Guardia CM, Keren-Kaplan T, Bonifacino JS.

J Cell Sci. 2016 Dec 1;129(23):4329-4339. Epub 2016 Oct 31. Review.

18.

Imaging the Polarized Sorting of Proteins from the Golgi Complex in Live Neurons.

Farías GG, Britt DJ, Bonifacino JS.

Methods Mol Biol. 2016;1496:13-30. doi: 10.1007/978-1-4939-6463-5_2.

PMID:
27631998
19.

Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon.

Guo X, Farías GG, Mattera R, Bonifacino JS.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5318-27. doi: 10.1073/pnas.1601844113. Epub 2016 Aug 24.

20.

TSSC1 is novel component of the endosomal retrieval machinery.

Gershlick DC, Schindler C, Chen Y, Bonifacino JS.

Mol Biol Cell. 2016 Sep 15;27(18):2867-78. doi: 10.1091/mbc.E16-04-0209. Epub 2016 Jul 20.

21.

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.

Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W.

Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9.

22.

Immunoprecipitation.

Bonifacino JS, Gershlick DC, Dell'Angelica EC.

Curr Protoc Cell Biol. 2016 Jun 1;71. doi: 10.1002/cpcb.3.

PMID:
27245424
23.

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells.

Klinger SC, Højland A, Jain S, Kjolby M, Madsen P, Svendsen AD, Olivecrona G, Bonifacino JS, Nielsen MS.

FEBS J. 2016 Jul;283(13):2476-93. doi: 10.1111/febs.13758. Epub 2016 Jun 6.

24.

Mechanisms of Polarized Organelle Distribution in Neurons.

Britt DJ, Farías GG, Guardia CM, Bonifacino JS.

Front Cell Neurosci. 2016 Mar 31;10:88. doi: 10.3389/fncel.2016.00088. eCollection 2016. Review.

25.

Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering.

Raza MH, Mattera R, Morell R, Sainz E, Rahn R, Gutierrez J, Paris E, Root J, Solomon B, Brewer C, Basra MA, Khan S, Riazuddin S, Braun A, Bonifacino JS, Drayna D.

Am J Hum Genet. 2015 Nov 5;97(5):715-25. doi: 10.1016/j.ajhg.2015.10.007.

26.

Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex.

Mattera R, Guardia CM, Sidhu SS, Bonifacino JS.

J Biol Chem. 2015 Dec 25;290(52):30736-49. doi: 10.1074/jbc.M115.683409. Epub 2015 Nov 5.

27.

Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone.

Farías GG, Guardia CM, Britt DJ, Guo X, Bonifacino JS.

Cell Rep. 2015 Nov 10;13(6):1221-1232. doi: 10.1016/j.celrep.2015.09.074. Epub 2015 Oct 29.

28.

Formation of Tubulovesicular Carriers from Endosomes and Their Fusion to the trans-Golgi Network.

Hierro A, Gershlick DC, Rojas AL, Bonifacino JS.

Int Rev Cell Mol Biol. 2015;318:159-202. doi: 10.1016/bs.ircmb.2015.05.005. Epub 2015 Jul 8. Review.

PMID:
26315886
29.

BORC, a multisubunit complex that regulates lysosome positioning.

Pu J, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS.

Dev Cell. 2015 Apr 20;33(2):176-88. doi: 10.1016/j.devcel.2015.02.011.

30.

EARP is a multisubunit tethering complex involved in endocytic recycling.

Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS.

Nat Cell Biol. 2015 May;17(5):639-50. doi: 10.1038/ncb3129. Epub 2015 Mar 23.

31.

Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1.

Jain S, Farías GG, Bonifacino JS.

Mol Biol Cell. 2015 Jan 15;26(2):218-28. doi: 10.1091/mbc.E14-07-1177. Epub 2014 Nov 5.

32.

HIV-1 Vpu accessory protein induces caspase-mediated cleavage of IRF3 transcription factor.

Park SY, Waheed AA, Zhang ZR, Freed EO, Bonifacino JS.

J Biol Chem. 2014 Dec 19;289(51):35102-10. doi: 10.1074/jbc.M114.597062. Epub 2014 Oct 28.

33.

Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.

Amorim NA, da Silva EM, de Castro RO, da Silva-Januário ME, Mendonça LM, Bonifacino JS, da Costa LJ, daSilva LL.

J Biol Chem. 2014 Oct 3;289(40):27744-56. doi: 10.1074/jbc.M114.560193. Epub 2014 Aug 12.

34.

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.

Bonnemaison M, Bäck N, Lin Y, Bonifacino JS, Mains R, Eipper B.

Traffic. 2014 Oct;15(10):1099-121. doi: 10.1111/tra.12194. Epub 2014 Aug 15.

35.

Co-assembly of viral envelope glycoproteins regulates their polarized sorting in neurons.

Mattera R, Farías GG, Mardones GA, Bonifacino JS.

PLoS Pathog. 2014 May 15;10(5):e1004107. doi: 10.1371/journal.ppat.1004107. eCollection 2014 May.

36.

Going forward with retromer.

Farias GG, Gershlick DC, Bonifacino JS.

Dev Cell. 2014 Apr 14;29(1):3-4. doi: 10.1016/j.devcel.2014.03.018.

37.

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.

Ren X, Park SY, Bonifacino JS, Hurley JH.

Elife. 2014;3:e01754. doi: 10.7554/eLife.01754. Epub 2014 Jan 28.

38.

Adaptor proteins involved in polarized sorting.

Bonifacino JS.

J Cell Biol. 2014 Jan 6;204(1):7-17. doi: 10.1083/jcb.201310021. Review.

39.

Vesicular transport earns a Nobel.

Bonifacino JS.

Trends Cell Biol. 2014 Jan;24(1):3-5. doi: 10.1016/j.tcb.2013.11.001.

40.

The adaptor protein-1 μ1B subunit expands the repertoire of basolateral sorting signal recognition in epithelial cells.

Guo X, Mattera R, Ren X, Chen Y, Retamal C, González A, Bonifacino JS.

Dev Cell. 2013 Nov 11;27(3):353-66. doi: 10.1016/j.devcel.2013.10.006.

41.

Cargo recognition in clathrin-mediated endocytosis.

Traub LM, Bonifacino JS.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a016790. doi: 10.1101/cshperspect.a016790. Review.

42.

Structural basis for the interaction of the Golgi-Associated Retrograde Protein Complex with the t-SNARE Syntaxin 6.

Abascal-Palacios G, Schindler C, Rojas AL, Bonifacino JS, Hierro A.

Structure. 2013 Sep 3;21(9):1698-706. doi: 10.1016/j.str.2013.06.025. Epub 2013 Aug 8.

43.

Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER.

Zhang ZR, Bonifacino JS, Hegde RS.

Cell. 2013 Aug 1;154(3):609-22. doi: 10.1016/j.cell.2013.06.038. Epub 2013 Jul 25.

44.

Anchors aweigh: protein localization and transport mediated by transmembrane domains.

Cosson P, Perrin J, Bonifacino JS.

Trends Cell Biol. 2013 Oct;23(10):511-7. doi: 10.1016/j.tcb.2013.05.005. Epub 2013 Jun 24. Review.

45.

The clathrin adaptor complexes as a paradigm for membrane-associated allostery.

Canagarajah BJ, Ren X, Bonifacino JS, Hurley JH.

Protein Sci. 2013 May;22(5):517-29. doi: 10.1002/pro.2235. Epub 2013 Mar 18. Review.

46.

Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1.

Ren X, Farías GG, Canagarajah BJ, Bonifacino JS, Hurley JH.

Cell. 2013 Feb 14;152(4):755-67. doi: 10.1016/j.cell.2012.12.042.

47.

Structural basis for the recognition of tyrosine-based sorting signals by the μ3A subunit of the AP-3 adaptor complex.

Mardones GA, Burgos PV, Lin Y, Kloer DP, Magadán JG, Hurley JH, Bonifacino JS.

J Biol Chem. 2013 Mar 29;288(13):9563-71. doi: 10.1074/jbc.M113.450775. Epub 2013 Feb 12.

48.

Signal-mediated, AP-1/clathrin-dependent sorting of transmembrane receptors to the somatodendritic domain of hippocampal neurons.

Farías GG, Cuitino L, Guo X, Ren X, Jarnik M, Mattera R, Bonifacino JS.

Neuron. 2012 Sep 6;75(5):810-23. doi: 10.1016/j.neuron.2012.07.007.

49.

Nef-arious goings-on at the Golgi.

Hurley JH, Bonifacino JS.

Nat Struct Mol Biol. 2012 Jul 5;19(7):661-2. doi: 10.1038/nsmb.2304. No abstract available.

PMID:
22767237
50.

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.

Sitaram A, Dennis MK, Chaudhuri R, De Jesus-Rojas W, Tenza D, Setty SR, Wood CS, Sviderskaya EV, Bennett DC, Raposo G, Bonifacino JS, Marks MS.

Mol Biol Cell. 2012 Aug;23(16):3178-92. Epub 2012 Jun 20.

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