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Items: 1 to 50 of 71

1.

Recent advances in the genetics of frontotemporal dementia.

Sirkis DW, Geier EG, Bonham LW, Karch CM, Yokoyama JS.

Curr Genet Med Rep. 2019 Mar;7(1):41-52. doi: 10.1007/s40142-019-0160-6. Epub 2019 Jan 30.

PMID:
31687268
2.

Evidence-Based Criteria for Determining Peripapillary OCT Reliability.

Yohannan J, Cheng M, Da J, Chapagain S, Sotimehin A, Bonham LW, Mihailovic A, Boland M, Ramulu P.

Ophthalmology. 2019 Aug 29. pii: S0161-6420(19)31958-X. doi: 10.1016/j.ophtha.2019.08.027. [Epub ahead of print]

PMID:
31648802
3.

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.

Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS; International FTD-Genomics Consortium (IFGC).

Sci Rep. 2019 Jul 26;9(1):10854. doi: 10.1038/s41598-019-46415-1.

4.

The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.

Bonham LW, Sirkis DW, Yokoyama JS.

Front Immunol. 2019 Jun 4;10:1170. doi: 10.3389/fimmu.2019.01170. eCollection 2019.

5.

Alzheimer Disease-associated Cortical Atrophy Does not Differ Between Chinese and Whites.

Fan J, Tse M, Carr JS, Miller BL, Kramer JH, Rosen HJ, Bonham LW, Yokoyama JS.

Alzheimer Dis Assoc Disord. 2019 Jul-Sep;33(3):186-193. doi: 10.1097/WAD.0000000000000315.

PMID:
31094707
6.

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.

Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, Kukull WA, Tosun D, Weiner MW, Sperling RA, Bennett DA, Hyman BT, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative.

Brain. 2019 Feb 1;142(2):460-470. doi: 10.1093/brain/awy327.

PMID:
30689776
7.

Immunological signatures in frontotemporal lobar degeneration.

Sirkis DW, Bonham LW, Karch CM, Yokoyama JS.

Curr Opin Neurol. 2019 Apr;32(2):272-278. doi: 10.1097/WCO.0000000000000665.

PMID:
30672824
8.

Does Phase-Contrast Imaging through the Cerebral Aqueduct Predict the Outcome of Lumbar CSF Drainage or Shunt Surgery in Patients with Suspected Adult Hydrocephalus?

Blitz AM, Shin J, Balédent O, Pagé G, Bonham LW, Herzka DA, Moghekar AR, Rigamonti D.

AJNR Am J Neuroradiol. 2018 Dec;39(12):2224-2230. doi: 10.3174/ajnr.A5857. Epub 2018 Nov 22.

PMID:
30467214
9.

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.

Geier EG, Bourdenx M, Storm NJ, Cochran JN, Sirkis DW, Hwang JH, Bonham LW, Ramos EM, Diaz A, Van Berlo V, Dokuru D, Nana AL, Karydas A, Balestra ME, Huang Y, Russo SP, Spina S, Grinberg LT, Seeley WW, Myers RM, Miller BL, Coppola G, Lee SE, Cuervo AM, Yokoyama JS.

Acta Neuropathol. 2019 Jan;137(1):71-88. doi: 10.1007/s00401-018-1925-9. Epub 2018 Oct 31.

PMID:
30382371
10.

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.

Bonham LW, Steele NZR, Karch CM, Manzoni C, Geier EG, Wen N, Ofori-Kuragu A, Momeni P, Hardy J, Miller ZA, Hess CP, Lewis P, Miller BL, Seeley WW, Baranzini SE, Desikan RS, Ferrari R, Yokoyama JS; International FTD-Genomics Consortium (IFGC).

Neurol Genet. 2018 Oct 1;4(5):e266. doi: 10.1212/NXG.0000000000000266. eCollection 2018 Oct.

11.

MR Imaging-Guided Cryoneurolysis of the Sural Nerve.

Bonham LW, Phelps A, Rosson GD, Fritz J.

J Vasc Interv Radiol. 2018 Nov;29(11):1622-1624. doi: 10.1016/j.jvir.2018.06.004. Epub 2018 Sep 28. No abstract available.

PMID:
30274861
12.

Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex.

Li Y, Barkovich MJ, Karch CM, Nillo RM, Fan CC, Broce IJ, Tan CH, Cuneo D, Hess CP, Dillon WP, Glenn OA, Glastonbury CM, Olney N, Yokoyama JS, Bonham LW, Miller B, Kao A, Schmansky N, Fischl B, Andreassen OA, Jernigan T, Dale A, Barkovich AJ, Desikan RS, Sugrue LP.

Sci Rep. 2018 Sep 6;8(1):13373. doi: 10.1038/s41598-018-31075-4.

13.

Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease.

Carr JS, Bonham LW, Morgans AK, Ryan CJ, Yokoyama JS, Geier EG; Alzheimer’s Disease Neuroimaging Initiative.

Front Neurosci. 2018 Aug 7;12:529. doi: 10.3389/fnins.2018.00529. eCollection 2018.

14.

Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice.

Bonham LW, Geier EG, Steele NZR, Holland D, Miller BL, Dale AM, Desikan RS, Yokoyama JS; Alzheimer’s Disease Neuroimaging Initiative.

Front Neurosci. 2018 Jul 16;12:476. doi: 10.3389/fnins.2018.00476. eCollection 2018.

15.

Comparative Analysis of Body Radiologist to Neuroradiologist Evaluation of the Spine in Trauma Settings.

Zhou AL, Bonham LW, Verde F.

J Am Coll Radiol. 2018 Dec;15(12):1687-1691. doi: 10.1016/j.jacr.2018.03.002. Epub 2018 May 24.

PMID:
29804826
16.

CXCR4 involvement in neurodegenerative diseases.

Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess CP, Sugrue LP, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP).

Transl Psychiatry. 2018 Apr 11;8(1):73. doi: 10.1038/s41398-017-0049-7.

17.

Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.

Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J; International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS, Miller BL, Andreassen OA, Dale AM, Desikan RS, Sugrue LP.

PLoS Med. 2018 Jan 29;15(1):e1002504. doi: 10.1371/journal.pmed.1002504. eCollection 2018 Jan.

18.

Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.

Bonham LW, Evans DS, Liu Y, Cummings SR, Yaffe K, Yokoyama JS.

Am J Alzheimers Dis Other Demen. 2018 May;33(3):153-165. doi: 10.1177/1533317517739384. Epub 2018 Jan 16.

19.

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.

Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J; International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS, Miller BL, Andreassen OA, Dale AM, Desikan RS, Sugrue LP.

PLoS Med. 2018 Jan 9;15(1):e1002487. doi: 10.1371/journal.pmed.1002487. eCollection 2018 Jan. Erratum in: PLoS Med. 2018 Jan 29;15(1):e1002504.

20.

Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts.

Steele NZ, Bright AR, Lee SE, Fong JC, Bonham LW, Karydas A, Karbassi ID, Pribadi M, Meservey MA, Gallen MC, Ramos EM, Liaquat K, Hoffman CC, Krasner MR, Dodge W, L Miller B, Coppola G, Rankin KP, Yokoyama JS, Higgins JJ.

Adv Genomics Genet. 2018;8:23-33. doi: 10.2147/AGG.S164047. Epub 2018 Oct 25.

21.

Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.

Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative.

Acta Neuropathol. 2018 Jan;135(1):85-93. doi: 10.1007/s00401-017-1789-4. Epub 2017 Nov 24.

22.

High environmental ammonia exposure has developmental-stage specific and long-term consequences on the cortisol stress response in zebrafish.

Williams TA, Bonham LA, Bernier NJ.

Gen Comp Endocrinol. 2017 Dec 1;254:97-106. doi: 10.1016/j.ygcen.2017.09.024. Epub 2017 Sep 25.

PMID:
28958860
23.

Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.

Bonham LW, Sirkis DW, Fan J, Aparicio RE, Tse M, Ramos EM, Wang Q, Coppola G, Rosen HJ, Miller BL, Yokoyama JS.

Neurocase. 2017 Feb;23(1):65-69. doi: 10.1080/13554794.2017.1294182.

24.

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.

Steele NZ, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS.

PLoS Med. 2017 Mar 28;14(3):e1002272. doi: 10.1371/journal.pmed.1002272. eCollection 2017 Mar.

25.

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.

Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM.

PLoS Med. 2017 Mar 21;14(3):e1002258. doi: 10.1371/journal.pmed.1002258. eCollection 2017 Mar. Erratum in: PLoS Med. 2017 Mar 28;14 (3):e1002289.

26.

Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.

Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J; International FTD-Genomics Consortium (IFGC), Momeni P, Sugrue LP, Hess CP, James Barkovich A, Boxer AL, Seeley WW, Rabinovici GD, Rosen HJ, Miller BL, Schmansky NJ, Fischl B, Hyman BT, Dickson DW, Schellenberg GD, Andreassen OA, Dale AM, Desikan RS.

Acta Neuropathol. 2017 May;133(5):825-837. doi: 10.1007/s00401-017-1693-y. Epub 2017 Mar 7.

27.

Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.

Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB; International FTD-Genomics Consortium (IFGC),; International Parkinson's Disease Genomics Consortium (IPDGC),; International Genomics of Alzheimer's Project (IGAP),, Momeni P, Schellenberg GD, Dillon WP, Sugrue LP, Hess CP, Yokoyama JS, Bonham LW, Rabinovici GD, Miller BL, Andreassen OA, Dale AM, Hardy J, Desikan RS.

J Neurol Neurosurg Psychiatry. 2017 Feb;88(2):152-164. doi: 10.1136/jnnp-2016-314411. Epub 2016 Nov 29.

28.

Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.

Yokoyama JS, Marx G, Brown JA, Bonham LW, Wang D, Coppola G, Seeley WW, Rosen HJ, Miller BL, Kramer JH, Dubal DB.

Brain Imaging Behav. 2017 Apr;11(2):391-400. doi: 10.1007/s11682-016-9598-2.

29.

Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.

Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS.

Ann Clin Transl Neurol. 2016 Aug 26;3(9):668-77. doi: 10.1002/acn3.333. eCollection 2016 Sep.

30.

Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.

Sirkis DW, Bonham LW, Aparicio RE, Geier EG, Ramos EM, Wang Q, Karydas A, Miller ZA, Miller BL, Coppola G, Yokoyama JS.

Acta Neuropathol Commun. 2016 Sep 2;4(1):98. doi: 10.1186/s40478-016-0367-7.

31.

The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer's disease.

Bonham LW, Desikan RS, Yokoyama JS; Alzheimer’s Disease Neuroimaging Initiative.

Acta Neuropathol Commun. 2016 Jun 29;4(1):65. doi: 10.1186/s40478-016-0339-y.

32.

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.

Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2016 Jun 1;73(6):691-7. doi: 10.1001/jamaneurol.2016.0150.

33.

The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia.

Yokoyama JS, Bonham LW, Sturm VE, Adhimoolam B, Karydas A, Coppola G, Miller BL, Rankin KP.

Neuroimage Clin. 2015 Aug 18;9:283-90. doi: 10.1016/j.nicl.2015.07.017. eCollection 2015.

34.

APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals.

Feng W, Yokoyama JS, Yu S, Chen Y, Cheng Y, Bonham LW, Wang D, Shen Y, Wu W, Li C.

J Alzheimers Dis. 2015;47(4):1035-46. doi: 10.3233/JAD-150039.

35.

Design of a Dissolving Microneedle Platform for Transdermal Delivery of a Fixed-Dose Combination of Cardiovascular Drugs.

Quinn HL, Bonham L, Hughes CM, Donnelly RF.

J Pharm Sci. 2015 Oct;104(10):3490-500. doi: 10.1002/jps.24563. Epub 2015 Jul 6.

PMID:
26149914
36.

Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease.

Yokoyama JS, Bonham LW, Sears RL, Klein E, Karydas A, Kramer JH, Miller BL, Coppola G.

BMC Neurol. 2015 Mar 28;15:47. doi: 10.1186/s12883-015-0304-6.

37.

Variation in longevity gene KLOTHO is associated with greater cortical volumes.

Yokoyama JS, Sturm VE, Bonham LW, Klein E, Arfanakis K, Yu L, Coppola G, Kramer JH, Bennett DA, Miller BL, Dubal DB.

Ann Clin Transl Neurol. 2015 Mar;2(3):215-30. doi: 10.1002/acn3.161. Epub 2015 Jan 26.

38.

Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.

Yokoyama JS, Lee AK, Takada LT, Busovaca E, Bonham LW, Chao SZ, Tse M, He J, Schwarz CG, Carmichael OT, Matthews BR, Karydas A, Weiner MW, Coppola G, DeCarli CS, Miller BL, Rosen HJ.

PLoS One. 2015 Mar 4;10(3):e0118338. doi: 10.1371/journal.pone.0118338. eCollection 2015.

39.

Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations.

Lohela M, Casbon AJ, Olow A, Bonham L, Branstetter D, Weng N, Smith J, Werb Z.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5086-95. doi: 10.1073/pnas.1419899111. Epub 2014 Nov 10.

40.

Are temporal artery temperatures accurate enough to replace rectal temperature measurement in pediatric ED patients?

Reynolds M, Bonham L, Gueck M, Hammond K, Lowery J, Redel C, Rodriguez C, Smith S, Stanton A, Sukosd S, Craft M.

J Emerg Nurs. 2014 Jan;40(1):46-50. doi: 10.1016/j.jen.2012.07.007. Epub 2012 Nov 8.

PMID:
23142099
41.

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation.

MacDonald KP, Palmer JS, Cronau S, Seppanen E, Olver S, Raffelt NC, Kuns R, Pettit AR, Clouston A, Wainwright B, Branstetter D, Smith J, Paxton RJ, Cerretti DP, Bonham L, Hill GR, Hume DA.

Blood. 2010 Nov 11;116(19):3955-63. doi: 10.1182/blood-2010-02-266296. Epub 2010 Aug 3.

PMID:
20682855
42.

Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib.

La Rosée P, Jia T, Demehri S, Härtel N, de Vries P, Bonham L, Hollenback D, Singer JW, Melo JV, Druker BJ, Deininger MW.

Clin Cancer Res. 2006 Nov 1;12(21):6540-6.

43.

Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival.

Diefenbach CS, Soslow RA, Iasonos A, Linkov I, Hedvat C, Bonham L, Singer J, Barakat RR, Aghajanian C, Dupont J.

Cancer. 2006 Oct 1;107(7):1511-9.

44.

Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia.

Douvas MG, Hogan KN, Ji Y, Hollenback D, Bonham L, Singer JW, Mitchell BS.

Leuk Res. 2006 Aug;30(8):1027-36. Epub 2006 Feb 20.

PMID:
16488473
45.

Substrate specificity of lysophosphatidic acid acyltransferase beta -- evidence from membrane and whole cell assays.

Hollenback D, Bonham L, Law L, Rossnagle E, Romero L, Carew H, Tompkins CK, Leung DW, Singer JW, White T.

J Lipid Res. 2006 Mar;47(3):593-604. Epub 2005 Dec 20.

46.

Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies.

Springett GM, Bonham L, Hummer A, Linkov I, Misra D, Ma C, Pezzoni G, Di Giovine S, Singer J, Kawasaki H, Spriggs D, Soslow R, Dupont J.

Cancer Res. 2005 Oct 15;65(20):9415-25. Erratum in: Cancer Res. 2005 Dec 15;65(24):11785.

47.

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.

Clin Cancer Res. 2005 Jul 1;11(13):4857-66.

48.

Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.

Hideshima T, Chauhan D, Ishitsuka K, Yasui H, Raje N, Kumar S, Podar K, Mitsiades C, Hideshima H, Bonham L, Munshi NC, Richardson PG, Singer JW, Anderson KC.

Oncogene. 2005 Apr 28;24(19):3121-9.

PMID:
15735676
49.

Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta.

Gong B, Hong F, Kohm C, Bonham L, Klein P.

Bioorg Med Chem Lett. 2004 Mar 22;14(6):1455-9.

PMID:
15006381
50.

Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma.

Hideshima T, Chauhan D, Hayashi T, Podar K, Akiyama M, Mitsiades C, MItsiades N, Gong B, Bonham L, de Vries P, Munshi N, Richardson PG, Singer JW, Anderson KC.

Cancer Res. 2003 Dec 1;63(23):8428-36.

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