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Items: 20


Complement-mediated Damage to the Glycocalyx Plays a Role in Renal Ischemia-reperfusion Injury in Mice.

Bongoni AK, Lu B, McRae JL, Salvaris EJ, Toonen EJM, Vikstrom I, Baz Morelli A, Pearse MJ, Cowan PJ.

Transplant Direct. 2019 Mar 25;5(4):e341. doi: 10.1097/TXD.0000000000000881. eCollection 2019 Apr.


Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model.

Zhang S, Shaw-Boden J, Banz Y, Bongoni AK, Taddeo A, Spirig R, Nolte MW, Cowan PJ, Rieben R.

J Vasc Surg. 2018 Dec;68(6S):209S-221S.e2. doi: 10.1016/j.jvs.2017.10.072. Epub 2018 Feb 1.


Release of pig leukocytes and reduced human NK cell recruitment during ex vivo perfusion of HLA-E/human CD46 double-transgenic pig limbs with human blood.

Puga Yung G, Bongoni AK, Pradier A, Madelon N, Papaserafeim M, Sfriso R, Ayares DL, Wolf E, Klymiuk N, Bähr A, Constantinescu MA, Voegelin E, Kiermeir D, Jenni H, Rieben R, Seebach JD.

Xenotransplantation. 2018 Jan;25(1). doi: 10.1111/xen.12357. Epub 2017 Oct 22.


Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood.

Bongoni AK, Salvaris E, Nordling S, Klymiuk N, Wolf E, Ayares DL, Rieben R, Magnusson PU, Cowan PJ.

Sci Rep. 2017 Jun 30;7(1):4450. doi: 10.1038/s41598-017-04898-w.


Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice.

Bongoni AK, Lu B, Salvaris EJ, Roberts V, Fang D, McRae JL, Fisicaro N, Dwyer KM, Cowan PJ.

J Immunol. 2017 Jun 15;198(12):4837-4845. doi: 10.4049/jimmunol.1601943. Epub 2017 May 12.


Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.

Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE.

Basic Res Cardiol. 2017 May;112(3):20. doi: 10.1007/s00395-017-0610-9. Epub 2017 Mar 3.


Role of the plasma cascade systems in ischemia/reperfusion injury of bone.

Zhang S, Wotzkow C, Bongoni AK, Shaw-Boden J, Siegrist M, Taddeo A, Blank F, Hofstetter W, Rieben R.

Bone. 2017 Apr;97:278-286. doi: 10.1016/j.bone.2016.12.007. Epub 2017 Jan 31.


Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs.

Kamat P, Vandenberghe S, Christen S, Bongoni AK, Meier B, Rieben R, Khattab AA.

PLoS One. 2016 Dec 21;11(12):e0168541. doi: 10.1371/journal.pone.0168541. eCollection 2016.


Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation.

Bongoni AK, Klymiuk N, Wolf E, Ayares D, Rieben R, Cowan PJ.

Transplantation. 2016 Sep;100(9):1871-9. doi: 10.1097/TP.0000000000001188.


Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions.

Bongoni AK, Kiermeir D, Schnider J, Jenni H, Garimella P, Bähr A, Klymiuk N, Wolf E, Ayares D, Voegelin E, Constantinescu MA, Seebach JD, Rieben R.

Transplantation. 2015 Oct;99(10):2061-9. doi: 10.1097/TP.0000000000000746.


Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14.

Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE.

Immunobiology. 2015 Aug;220(8):999-1005. doi: 10.1016/j.imbio.2015.04.002. Epub 2015 Apr 27.


siRNA mediated knockdown of tissue factor expression in pigs for xenotransplantation.

Ahrens HE, Petersen B, Herrmann D, Lucas-Hahn A, Hassel P, Ziegler M, Kues WA, Baulain U, Baars W, Schwinzer R, Denner J, Rataj D, Werwitzke S, Tiede A, Bongoni AK, Garimella PS, Despont A, Rieben R, Niemann H.

Am J Transplant. 2015 May;15(5):1407-14. doi: 10.1111/ajt.13120. Epub 2015 Mar 23.


Porcine extrahepatic vascular endothelial asialoglycoprotein receptor 1 mediates xenogeneic platelet phagocytosis in vitro and in human-to-pig ex vivo xenoperfusion.

Bongoni AK, Kiermeir D, Denoyelle J, Jenni H, Burlak C, Seebach JD, Vögelin E, Constantinescu MA, Rieben R.

Transplantation. 2015 Apr;99(4):693-701. doi: 10.1097/TP.0000000000000553.


A single localized dose of enzyme-responsive hydrogel improves long-term survival of a vascularized composite allograft.

Gajanayake T, Olariu R, Leclère FM, Dhayani A, Yang Z, Bongoni AK, Banz Y, Constantinescu MA, Karp JM, Vemula PK, Rieben R, Vögelin E.

Sci Transl Med. 2014 Aug 13;6(249):249ra110. doi: 10.1126/scitranslmed.3008778.


Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

Bongoni AK, Kiermeir D, Jenni H, Bähr A, Ayares D, Klymiuk N, Wolf E, Voegelin E, Constantinescu MA, Seebach JD, Rieben R.

Xenotransplantation. 2014 May-Jun;21(3):230-43. doi: 10.1111/xen.12090. Epub 2014 Mar 17.


Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.

Wuensch A, Baehr A, Bongoni AK, Kemter E, Blutke A, Baars W, Haertle S, Zakhartchenko V, Kurome M, Kessler B, Faber C, Abicht JM, Reichart B, Wanke R, Schwinzer R, Nagashima H, Rieben R, Ayares D, Wolf E, Klymiuk N.

Transplantation. 2014 Jan 27;97(2):138-47. doi: 10.1097/TP.0b013e3182a95cbc.


Activation of the lectin pathway of complement in pig-to-human xenotransplantation models.

Bongoni AK, Kiermeir D, Jenni H, Wünsch A, Bähr A, Ayares D, Seebach JD, Wolf E, Klymiuk N, Constantinescu MA, Vögelin E, Rieben R.

Transplantation. 2013 Nov 15;96(9):791-9. doi: 10.1097/TP.0b013e3182a3a52b.


Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis.

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE.

J Immunol. 2013 Jul 15;191(2):819-27. doi: 10.4049/jimmunol.1201909. Epub 2013 Jun 12.


Development of a bead-based multiplex assay for the simultaneous detection of porcine inflammation markers using xMAP technology.

Bongoni AK, Lanz J, Rieben R, Banz Y.

Cytometry A. 2013 Jul;83(7):636-47. doi: 10.1002/cyto.a.22287. Epub 2013 Apr 10.


Ischemia/reperfusion injury of porcine limbs after extracorporeal perfusion.

Müller S, Constantinescu MA, Kiermeir DM, Gajanayake T, Bongoni AK, Vollbach FH, Meoli M, Plock J, Jenni H, Banic A, Rieben R, Vögelin E.

J Surg Res. 2013 May 1;181(1):170-82. doi: 10.1016/j.jss.2012.05.088. Epub 2012 Jun 17.


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