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Delivery of biologically active miR-34a in normal and cancer mammary epithelial cells by synthetic nanoparticles.

Panebianco F, Climent M, Malvindi MA, Pompa PP, Bonetti P, Nicassio F.

Nanomedicine. 2019 Jul;19:95-105. doi: 10.1016/j.nano.2019.03.013. Epub 2019 Apr 25.


p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.

Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabò A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG.

Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071.


Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer.

Bonetti P, Climent M, Panebianco F, Tordonato C, Santoro A, Marzi MJ, Pelicci PG, Ventura A, Nicassio F.

Oncogene. 2019 Jan;38(3):360-374. doi: 10.1038/s41388-018-0445-3. Epub 2018 Aug 9.


Insc:LGN tetramers promote asymmetric divisions of mammary stem cells.

Culurgioni S, Mari S, Bonetti P, Gallini S, Bonetto G, Brennich M, Round A, Nicassio F, Mapelli M.

Nat Commun. 2018 Mar 9;9(1):1025. doi: 10.1038/s41467-018-03343-4.


Can the optimal type of stent be predicted based on clinical risk factors? A subgroup analysis of the randomized BASKET-PROVE trial.

Vassalli G, Klersy C, De Servi S, Galatius S, Erne P, Eberli F, Rickli H, Hornig B, Bertel O, Bonetti P, Moccetti T, Kaiser C, Pfisterer M, Pedrazzini G; BASKET-PROVE Investigators.

Am Heart J. 2016 Mar;173:1-7. doi: 10.1016/j.ahj.2015.11.007. Epub 2015 Dec 1.


Degradation dynamics of microRNAs revealed by a novel pulse-chase approach.

Marzi MJ, Ghini F, Cerruti B, de Pretis S, Bonetti P, Giacomelli C, Gorski MM, Kress T, Pelizzola M, Muller H, Amati B, Nicassio F.

Genome Res. 2016 Apr;26(4):554-65. doi: 10.1101/gr.198788.115. Epub 2016 Jan 28.


The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs.

Boi M, Gaudio E, Bonetti P, Kwee I, Bernasconi E, Tarantelli C, Rinaldi A, Testoni M, Cascione L, Ponzoni M, Mensah AA, Stathis A, Stussi G, Riveiro ME, Herait P, Inghirami G, Cvitkovic E, Zucca E, Bertoni F.

Clin Cancer Res. 2015 Apr 1;21(7):1628-38. doi: 10.1158/1078-0432.CCR-14-1561. Epub 2015 Jan 26.


Tradeoff between bleeding and stent thrombosis in different dual antiplatelet therapy regimes: Importance of case fatality rates and effective treatment durations.

Jeger RV, Pfisterer ME, Sørensen R, von Felten S, Alber H, Bonetti PO, Eberli F, Erne P, Pedrazzini G, Rickli H, Galatius S, Kaiser CA; BASKET and BASKET-PROVE investigators.

Am Heart J. 2014 Nov;168(5):698-705. doi: 10.1016/j.ahj.2014.07.019. Epub 2014 Jul 30.


[Important classifications and scores in cardiology].

Bonetti PO.

Ther Umsch. 2013 Oct;70(10):581-8. doi: 10.1024/0040-5930/a000451. Review. German.


PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma.

Boi M, Rinaldi A, Kwee I, Bonetti P, Todaro M, Tabbò F, Piva R, Rancoita PM, Matolcsy A, Timar B, Tousseyn T, Rodríguez-Pinilla SM, Piris MA, Beà S, Campo E, Bhagat G, Swerdlow SH, Rosenwald A, Ponzoni M, Young KH, Piccaluga PP, Dummer R, Pileri S, Zucca E, Inghirami G, Bertoni F.

Blood. 2013 Oct 10;122(15):2683-93. doi: 10.1182/blood-2013-04-497933. Epub 2013 Sep 4.


Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma.

Bonetti P, Testoni M, Scandurra M, Ponzoni M, Piva R, Mensah AA, Rinaldi A, Kwee I, Tibiletti MG, Iqbal J, Greiner TC, Chan WC, Gaidano G, Piris MA, Cavalli F, Zucca E, Inghirami G, Bertoni F.

Blood. 2013 Sep 26;122(13):2233-41. doi: 10.1182/blood-2013-01-475772. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 8;123(19):3056.


Cancer risk among tetrafluoroethylene synthesis and polymerization workers.

Consonni D, Straif K, Symons JM, Tomenson JA, van Amelsvoort LG, Sleeuwenhoek A, Cherrie JW, Bonetti P, Colombo I, Farrar DG, Bertazzi PA.

Am J Epidemiol. 2013 Aug 1;178(3):350-8. doi: 10.1093/aje/kws588. Epub 2013 Jul 4.


Studies on metabolically depleted erythrocytes.

Reinhart SA, Schulzki T, Bonetti PO, Reinhart WH.

Clin Hemorheol Microcirc. 2014;56(2):161-73. doi: 10.3233/CH-131682.


Intracellular drug release from curcumin-loaded PLGA nanoparticles induces G2/M block in breast cancer cells.

Verderio P, Bonetti P, Colombo M, Pandolfi L, Prosperi D.

Biomacromolecules. 2013 Mar 11;14(3):672-82. doi: 10.1021/bm3017324. Epub 2013 Feb 15.


Botulinum toxin type A injection into the gastrocnemius muscle for spastic equinus in adults with stroke: a randomized controlled trial comparing manual needle placement, electrical stimulation and ultrasonography-guided injection techniques.

Picelli A, Tamburin S, Bonetti P, Fontana C, Barausse M, Dambruoso F, Gajofatto F, Santilli V, Smania N.

Am J Phys Med Rehabil. 2012 Nov;91(11):957-64. doi: 10.1097/PHM.0b013e318269d7f3.


Exogenous surfactant replacement: how to deliver it?

Biban P, Chini L, Bonetti P, Sacco F, Zaglia F, Santuz P.

Acta Biomed. 2012;83 Suppl 1:27-32. Review.


Lutein and zeaxanthin supplementation in preterm very low-birth-weight neonates in neonatal intensive care units: a multicenter randomized controlled trial.

Manzoni P, Guardione R, Bonetti P, Priolo C, Maestri A, Mansoldo C, Mostert M, Anselmetti G, Sardei D, Bellettato M, Biban P, Farina D.

Am J Perinatol. 2013 Jan;30(1):25-32. doi: 10.1055/s-0032-1321494. Epub 2012 Jul 6.


A patient with pulmonary embolism and a mass in the left atrium.

Nägele R, Bonetti PO, Mayer KA.

Heart. 2012 Aug;98(16):1260. doi: 10.1136/heartjnl-2011-301445. Epub 2012 Jun 15. No abstract available.


Incidence and time frame of life-threatening arrhythmias in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.

Cricri P, Trachsel LD, Müller P, Wäckerlin A, Reinhart WH, Bonetti PO.

Swiss Med Wkly. 2012 Jun 8;142:w13604. doi: 10.4414/smw.2012.13604. eCollection 2012.


Accuracy of botulinum toxin type A injection into the gastrocnemius muscle of adults with spastic equinus: manual needle placement and electrical stimulation guidance compared using ultrasonography.

Picelli A, Bonetti P, Fontana C, Barausse M, Dambruoso F, Gajofatto F, Tamburin S, Girardi P, Gimigliano R, Smania N.

J Rehabil Med. 2012 May;44(5):450-2. doi: 10.2340/16501977-0970.


Applicability of a new robotic walking aid in a patient with cerebral palsy. Case report.

Smania N, Gandolfi M, Marconi V, Calanca A, Geroin C, Piazza S, Bonetti P, Fiorini P, Cosentino A, Capelli C, Conte D, Bendinelli M, Munari D, Ianes P, Fiaschi A, Picelli A.

Eur J Phys Rehabil Med. 2012 Mar;48(1):147-53.


Is spastic muscle echo intensity related to the response to botulinum toxin type A in patients with stroke? A cohort study.

Picelli A, Bonetti P, Fontana C, Barausse M, Dambruoso F, Gajofatto F, Girardi P, Manca M, Gimigliano R, Smania N.

Arch Phys Med Rehabil. 2012 Jul;93(7):1253-8. doi: 10.1016/j.apmr.2012.02.005. Epub 2012 Apr 12.


Incidence of acute myocardial infarction after implementation of a public smoking ban in Graubünden, Switzerland: two year follow-up.

Bonetti PO, Trachsel LD, Kuhn MU, Schulzki T, Erne P, Radovanovic D, Reinhart WH.

Swiss Med Wkly. 2011 May 27;141:w13206. doi: 10.4414/smw.2011.13206. eCollection 2011.


The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway.

Martinelli P, Bonetti P, Sironi C, Pruneri G, Fumagalli C, Raviele PR, Volorio S, Pileri S, Chiarle R, McDuff FK, Tusi BK, Turner SD, Inghirami G, Pelicci PG, Colombo E.

Blood. 2011 Jun 16;117(24):6617-26. doi: 10.1182/blood-2010-08-301135. Epub 2011 Apr 25.


Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect.

Mannheim D, Herrmann J, Bonetti PO, Lavi R, Lerman LO, Lerman A.

Atherosclerosis. 2011 Jun;216(2):283-91. doi: 10.1016/j.atherosclerosis.2011.02.036. Epub 2011 Feb 24.


Improved gait after repetitive locomotor training in children with cerebral palsy.

Smania N, Bonetti P, Gandolfi M, Cosentino A, Waldner A, Hesse S, Werner C, Bisoffi G, Geroin C, Munari D.

Am J Phys Med Rehabil. 2011 Feb;90(2):137-49. doi: 10.1097/PHM.0b013e318201741e.


Effect of brief secondhand smoke exposure on endothelial function and circulating markers of inflammation.

Bonetti PO, Lardi E, Geissmann C, Kuhn MU, Brüesch H, Reinhart WH.

Atherosclerosis. 2011 Mar;215(1):218-22. doi: 10.1016/j.atherosclerosis.2010.12.011. Epub 2010 Dec 22. Erratum in: Atherosclerosis. 2011 Aug;217(2):549.


Complement inhibition to treat myocardial infarction?

Gerber B, Kyburz T, Reinhart WH, Bonetti PO, Stussi G.

BMJ Case Rep. 2011 Apr 26;2011. pii: bcr0120113701. doi: 10.1136/bcr.01.2011.3701.


Microenvironmental control of malignancy exerted by RNASET2, a widely conserved extracellular RNase.

Acquati F, Bertilaccio S, Grimaldi A, Monti L, Cinquetti R, Bonetti P, Lualdi M, Vidalino L, Fabbri M, Sacco MG, van Rooijen N, Campomenosi P, Vigetti D, Passi A, Riva C, Capella C, Sanvito F, Doglioni C, Gribaldo L, Macchi P, Sica A, Noonan DM, Ghia P, Taramelli R.

Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1104-9. doi: 10.1073/pnas.1013746108. Epub 2010 Dec 28.


[Pier Luigi Viola and vinyl chloride: notes that were never published].

Zocchetti C, Bonetti P.

Med Lav. 2010 Jul-Aug;101(4):303-13. Italian.


Drug-eluting versus bare-metal stents in large coronary arteries.

Kaiser C, Galatius S, Erne P, Eberli F, Alber H, Rickli H, Pedrazzini G, Hornig B, Bertel O, Bonetti P, De Servi S, Brunner-La Rocca HP, Ricard I, Pfisterer M; BASKET–PROVE Study Group.

N Engl J Med. 2010 Dec 9;363(24):2310-9. doi: 10.1056/NEJMoa1009406. Epub 2010 Nov 16.


Ultrasound-guided lung recruitment in a young infant with ARDS.

Santuz P, Bonetti P, Serra A, Biban P.

Paediatr Anaesth. 2010 Sep;20(9):895-6. doi: 10.1111/j.1460-9592.2010.03379.x. No abstract available.


Acute effects of short-term exposure to second-hand smoke on induced platelet aggregation.

Lardi E, Ott C, Schulzki T, Kuhn M, Bonetti PO, Reinhart WH.

Clin Hemorheol Microcirc. 2010;45(2-4):359-64. doi: 10.3233/CH-2010-1318.


Reduced incidence of acute myocardial infarction in the first year after implementation of a public smoking ban in Graubuenden, Switzerland.

Trachsel LD, Kuhn MU, Reinhart WH, Schulzki T, Bonetti PO.

Swiss Med Wkly. 2010;140(9-10):133-8. doi: smw-12955.


Right coronary artery to coronary sinus fistula.

Laske A, Ritter M, Bonetti PO.

Eur J Cardiothorac Surg. 2009 Dec;36(6):1079-80. doi: 10.1016/j.ejcts.2009.06.049. Epub 2009 Oct 22. No abstract available.


Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma.

Bonetti P, Davoli T, Sironi C, Amati B, Pelicci PG, Colombo E.

J Cell Biol. 2008 Jul 14;182(1):19-26. doi: 10.1083/jcb.200711040.


Drug-eluting stents compared with bare metal stents improve late outcome after saphenous vein graft but not after large native vessel interventions.

Jeger RV, Schneiter S, Kaiser C, Bonetti PO, Brunner-La Rocca H, Handke M, Osswald S, Buser PT, Pfisterer ME; BASKET Investigators.

Cardiology. 2009;112(1):49-55. doi: 10.1159/000137699. Epub 2008 Jun 26.


Drug-eluting or bare-metal stents for large coronary vessel stenting? The BASKET-PROVE (PROspective Validation Examination) trial: study protocol and design.

Pfisterer M, Bertel O, Bonetti PO, Brunner-La Rocca HP, Eberli FR, Erne P, Galatius S, Hornig B, Kiowski W, Pachinger O, Pedrazzini G, Rickli H, De Servi S, Kaiser C; BASKET-PROVE Investigators.

Am Heart J. 2008 Apr;155(4):609-14. doi: 10.1016/j.ahj.2007.11.011. Epub 2008 Feb 21.


Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit.

Cardinale S, Cisterna B, Bonetti P, Aringhieri C, Biggiogera M, Barabino SM.

Mol Biol Cell. 2007 Apr;18(4):1282-92. Epub 2007 Jan 31.


Endothelial function and cerebrovascular disease: implications for diagnosis and treatment.

Elesber AA, Bonetti PO, Lerman A.

Curr Treat Options Cardiovasc Med. 2006 May;8(3):213-9.


Watching football on TV may potentially be life-threatening.

Bonetti PO, Hunziker PR.

Swiss Med Wkly. 2006 Apr 1;136(13-14):228. No abstract available.


Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.

Colombo E, Martinelli P, Zamponi R, Shing DC, Bonetti P, Luzi L, Volorio S, Bernard L, Pruneri G, Alcalay M, Pelicci PG.

Cancer Res. 2006 Mar 15;66(6):3044-50.


Coronary stent infection: a rare but severe complication of percutaneous coronary intervention.

Kaufmann BA, Kaiser C, Pfisterer ME, Bonetti PO.

Swiss Med Wkly. 2005 Aug 20;135(33-34):483-7. Review.


Nucleophosmin is required for DNA integrity and p19Arf protein stability.

Colombo E, Bonetti P, Lazzerini Denchi E, Martinelli P, Zamponi R, Marine JC, Helin K, Falini B, Pelicci PG.

Mol Cell Biol. 2005 Oct;25(20):8874-86.


Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitäts Trial (BASKET).

Kaiser C, Brunner-La Rocca HP, Buser PT, Bonetti PO, Osswald S, Linka A, Bernheim A, Zutter A, Zellweger M, Grize L, Pfisterer ME; BASKET Investigators.

Lancet. 2005 Sep 10-16;366(9489):921-9. Erratum in: Lancet. 2005 Dec 17;366(9503):2086.


Influence of revascularization on long-term outcome in patients > or =75 years of age with diabetes mellitus and angina pectoris.

Jeger RV, Bonetti PO, Zellweger MJ, Tobler D, Kaiser CA, Osswald S, Buser PT, Pfisterer ME.

Am J Cardiol. 2005 Jul 15;96(2):193-8.


Bosentan preserves endothelial function in mice overexpressing APP.

Elesber AA, Bonetti PO, Woodrum JE, Zhu XY, Lerman LO, Younkin SG, Lerman A.

Neurobiol Aging. 2006 Mar;27(3):446-50.


Long-term benefits and limitations of combined antianginal drug therapy in elderly patients with symptomatic chronic coronary artery disease.

Bonetti PO, Kaiser C, Zellweger MJ, Grize L, Erne P, Schoenenberger RA, Pfisterer ME; TIME Investigators.

J Cardiovasc Pharmacol Ther. 2005 Mar;10(1):29-37.


Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia.

Bonetti PO, Pumper GM, Higano ST, Holmes DR Jr, Kuvin JT, Lerman A.

J Am Coll Cardiol. 2004 Dec 7;44(11):2137-41.


Successful treatment of symptomatic coronary endothelial dysfunction with enhanced external counterpulsation.

Bonetti PO, Gadasalli SN, Lerman A, Barsness GW.

Mayo Clin Proc. 2004 May;79(5):690-2.


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